1.Correlation analysis of serum thyroglobulin antibody with the risk of thyroid cancer in patients with thyroid nodule
Shanglin HUANG ; Lijun FU ; Xinguang QIU
Chinese Journal of Endocrine Surgery 2019;13(1):9-12
Objective To study the association between serum thyroglobulin antibody(TgAb) and the risk of thyroid cancer (TC) in patients with thyroid nodule (TN).Methods The determination of benign and malignant TN was based on routine pathological biopsy of postoperative thyroid tissues.Serum TgAb level of 1257 patients with TN undergoing surgery from 1st Sep.2015 to 31st Dec.2016 was determined by electrochemiluminescence immunoassay.A retrospective cohort analysis was performed.The correlation between the serum TgAb level and the benign or malignant rate of thyroid nodule was determined by Pearson Chi-square test.Results Among the 1257 patients,there were 196 patients whose TgAb level was high.Among these 196 patients,there were 94 patients with benign TN,with the benign rate of 47.96% and there were 102 patients with malignant TN,with the malignant rate of 52.04%.There were also 1061 patients whose TgAb level was normal,among these 1061 patients,there were 654 patients with benign TN,with the benign rate of 61.64% and there were 407 patients with malignant TN,with the malignant rate of 38.36%.For papillary thyroid carcinoma(PTC)patients,x2=23.101 9,OR=1.7218,the 95% CI of OR was(1.382 9,2.375 4).For follicular thyroid carcinoma(FTC) patients,x2=0.287 5,P>0.01.For medullary thyroid carcinoma (MTC) patients,P=0.048 9>0.01.Conclusions Among patients with TN,PTC rate of the patients whose serun TgAb level is high is higher than patients whose serum TgAb level is normal.But among the patients with TN,we do not think that FTC and MTC rate of patients whose serun TgAb level is high is higher than patients whose serum TgAb level is normal.
2.Clinical Study of Influent Factors on Normal Intraabdominal Pressure
Xinping YANG ; Weimin HUANG ; Shanglin ZHU ; Hongchi JIANG ;
Chinese Journal of Bases and Clinics in General Surgery 2003;0(05):-
Objective To investigate the influent factors on normal intraabdominal pressure (IAP) and establish the IAP regressive equation. Methods The IAPs of 106 hospitalized patients were determined through monitoring the bladder pressures. The relationship between IAP and 14 factors including age, gender, height, weight, body mass index (BMI), previous and recent abdominal surgical history, reasons for admission,complications and their quantities were analyzed,respectively Results The mean IAP of the hospitalized patients was 5.5 mm Hg with a range from 0.4 mm Hg to 12.8 mm Hg. The difference among IAPs of different grades of BMIs had statistical significance ( F =5.550, P 0.05). Conclusion Normal IAP is possibly influenced by gender and BMI,and it is individually different.

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