We describe 2 cases of patients with loss of hepatic arterial flow during surgery for pancreatic head cancer due to celiac stenosis caused by median arcuate ligament compression. The first case underwent pylorus-resecting pancreatoduodenectomy for pancreatic head cancer. After resection of the gastroduodenal artery, flow in the common hepatic artery disappeared, and celiac axis stenosis was identified. Interventional stent insertion was attempted, however, it failed due to the acute angle of the celiac orifice (os). This problem was resolved by arterial reconstruction. The second case underwent pylorus-preserving pancreatoduodenectomy for pancreatic head cancer and the same phenomenon occurred during the procedure. Interventional stent insertion was also tried; in this patient, however, it failed due to the acute angle of the celiac os. The problem was resolved by changing a femoral approach to a brachial approach, and the stent was inserted into the celiac os successfully.
Arteries ; Constriction, Pathologic* ; Head and Neck Neoplasms ; Hepatic Artery ; Humans ; Ligaments ; Pancreaticoduodenectomy* ; Stents

We describe 2 cases of patients with loss of hepatic arterial flow during surgery for pancreatic head cancer due to celiac stenosis caused by median arcuate ligament compression. The first case underwent pylorus-resecting pancreatoduodenectomy for pancreatic head cancer. After resection of the gastroduodenal artery, flow in the common hepatic artery disappeared, and celiac axis stenosis was identified. Interventional stent insertion was attempted, however, it failed due to the acute angle of the celiac orifice (os). This problem was resolved by arterial reconstruction. The second case underwent pylorus-preserving pancreatoduodenectomy for pancreatic head cancer and the same phenomenon occurred during the procedure. Interventional stent insertion was also tried; in this patient, however, it failed due to the acute angle of the celiac os. The problem was resolved by changing a femoral approach to a brachial approach, and the stent was inserted into the celiac os successfully.
Arteries ; Constriction, Pathologic* ; Head and Neck Neoplasms ; Hepatic Artery ; Humans ; Ligaments ; Pancreaticoduodenectomy* ; Stents

The present research was conducted through the research fund of Dankook University in 2006. Rectal recurrence of gastric cancer is uncommon. A few cases have been reported, with the majority of them associated with peritoneal recurrence. A 71-year-old man visited our hospital complaining of bowel habit changes and fecal incontinence. He had undergone radical subtotal gastrectomy and postoperative adjuvant chemotherapy for advanced gastric cancer 9 years earlier. Colonoscopy showed a rigidly constricted and erythematous rectum. Abdominopelvic CT showed diffuse rectal wall thickening with enhancement. PET-CT showed a hot uptake in the corresponding area on abdominopelvic CT scan, with no evidence of distant metastasis. We performed transanal full thickness biopsy and confirmed a diagnosis of adenocarcinoma pathologically similar to the former gastric cancer. The patient was diagnosed with solitary rectal recurrence simulating linitis plastica, without gastric remnant recurrence. We report this case with a review of the literature.
Adenocarcinoma ; Aged ; Biopsy ; Chemotherapy, Adjuvant ; Colonoscopy ; Fecal Incontinence ; Financial Management ; Gastrectomy ; Gastric Stump ; Humans ; Linitis Plastica ; Neoplasm Metastasis ; Rectum ; Recurrence ; Stomach Neoplasms

Since genetic abnormalities of human cancer are greatly geographically dependent, cultural and environmental backgrounds are thought to be closely related to the carcinogenic process. In the present study, eight human cell lines were established by culture from untreated carcinomas of the oral cancer, of which five were from primary oral squamous cell carcinomas (OSC), one from a mucoepidermoid carcinoma (MEC) and one each originating from metastatic OSC and MEC. All the studied tumor lines grew as monolayers, and showed: i) an epithelial origin by the presence of cytokeratin, and ii) tumorigenic potential in nude mice. Western blot analysis revealed i) over expression of EGFR in six of the cell lines ii) decreased expression of E- cadherin in six cell lines compared to normal human oral mucosa. A mutational analysis showed: point mutations of p53 at exon 7, with transversion, and at exon 8, with transition. These well-characterized human YD cell lines should serve as useful tools in the study of the molecular pathogenesis and biological characteristics of head and neck cancer cells, and in the future testing of new therapeutic reagents for oral cancer.
Adult ; Aged ; Animals ; Base Sequence ; Carcinoma, Mucoepidermoid/genetics/*metabolism/*pathology ; Carcinoma, Squamous Cell/genetics/*metabolism/*pathology ; *Cell Line, Tumor ; Epithelial Cells/metabolism ; Female ; Humans ; Male ; Mice ; Mice, Nude ; Middle Aged ; Mouth Neoplasms/genetics/*metabolism/*pathology ; Mutation/genetics ; Papillomavirus/physiology ; Receptor, Epidermal Growth Factor/genetics/metabolism ; Research Support, Non-U.S. Gov't ; Tumor Markers, Biological ; Tumor Suppressor Protein p53/genetics/metabolism ; Xenograft Model Antitumor Assays

BACKGROUND AND OBJECTIVES: Adenoidectomy is one of the most common procedures in the field of otolaryngology, and various hemostatic agents and techniques have been used for stanching the wound of adenoidectomy site. The aim of this study is to evaluate the hemostatic efficacy of topical application of cold hydrogen peroxide in adenoidectomy. MATERIALS AND METHOD: We randomly divided 120 candidates (aged 3-14 years) for adenoidectomy into 4 groups, and 3% hydrogen peroxide (3+/-2degrees C), 3% hydrogen peroxide (20+/-2degrees C), 0.05% epinephrine solution (3+/-2degrees C) and 0.05% epinephrine solution (20+/-2degrees C) were applied topically to each group respectively. The time consumed for bleeding control, and the hemostatic findings of adenoidectomy wound at 5 minutes after curretage, 6 hours after operation of each group were compared. RESULTS: The use of cold hydrogen peroxide significantly reduced intraoperative time when compared with uisng other hemostatic agents. And in the adenoidectomy site, it is found that the incidence of oozing and active bleeding decreased when cold hydrogen was applied. CONCLUSION: Cold hydrogen peroxide is a useful agent for hemostasis in adenoidectomy.
Adenoidectomy* ; Epinephrine ; Hemorrhage ; Hemostasis ; Hemostatics ; Hydrogen Peroxide* ; Hydrogen* ; Incidence ; Otolaryngology ; Wounds and Injuries

OBJECTIVE: To identify and evaluate the lateral border zone by comparing the size and distribution of the abnormal signal area demonstrated by MR imaging with the infarct area revealed by pathological examination in a reperfused myocardial infarction cat model. MATERIALS AND METHODS: In eight cats, the left anterior descending coronary artery was occluded for 90 minutes, and this was followed by 90 minutes of reper-fusion. ECG-triggered breath-hold turbo spin-echo T2-weighted MR images were initially obtained along the short axis of the heart before the administration of contrast media. After the injection of Gadomer-17 and Gadophrin-2, contrast-enhanced T1-weighted MR images were obtained for three hours. The size of the abnormal signal area seen on each image was compared with that of the infarct area after TTC staining. To assess ultrastructural changes in the myocardium at the infarct area, lateral border zone and normal myocardium, electron microscopic examination was performed. RESULTS: The high signal area seen on T2-weighted images and the enhanced area seen on Gadomer-17-enhanced T1WI were larger than the enhanced area on Gadophrin-2-enhanced T1WI and the infarct area revealed by TTC staining; the difference was expressed as a percentage of the size of the total left ventricle mass (T2= 39.2 %; Gadomer-17 =37.25 % vs Gadophrin-2 = 29.6 %; TTC staining = 28.2 %; p < 0.05). The ultrastructural changes seen at the lateral border zone were compatible with reversible myocardial damage. CONCLUSION: In a reperfused myocardial infarction cat model, the presence and size of the lateral border zone can be determined by means of Gadomer-17- and Gadophrin-2-enhanced MR imaging.
Animal ; Cats ; Contrast Media ; Gadolinium ; Magnetic Resonance Imaging/*methods ; Mesoporphyrins/diagnostic use ; Metalloporphyrins/diagnostic use ; Myocardial Infarction/*pathology ; Myocardial Reperfusion ; Myocardium/pathology ; Support, Non-U.S. Gov't

It is very important to collect information on the nutritional status of the Korean population for the development of health promotion programs including nutrition. The purpose of this study was to assess the nutritional status of various population living in selected areas for model nutritional work. Seven hundred eighty households(30 households per each area)from 26 areas participated in this study from November 1 to November 20, 1996. Dietary intake data for two consecutive days were collected at household level by a weighting method. The mean energy intake of the subjects(1,934 kcal) was higher than that resulted from the '95 Korean National Nutrition Survey(1,839 kcal). The proportion of energy derived from cereals was 60.1%. The proportion of total protein intake from animal sources was 49.4%. These results were similar to those found in the '95 Korean National Nutrition Survey. Most nutrients(except iron, thiamin, riboflavin, vitamin C, and crude fiber) were higher than the result of the '95 Korean National Nutrition Survey. However, the average iron intake was about 68% of the result of '95 Korean National Nutrition Survey. This may be due to the adjustment of iron content in rice(3.7mg/100g-->0.5mg/100g) included in nutrient database for calculating nutrient intakes. The mean energy contribution from carbohydrate, protein, and fat were 64.2%, 16.4% and 19.4%, respectively. Significant differences of nutrient intakes were noted among some areas, which may be due to different food intake patterns according to the needs of the particular area. Therefore, the result of this study indicates that there are significant differences in food and nutrient intakes among the areas, suggesting that nutritional improvement programs may need to be developed differently by areas.
Animals ; Ascorbic Acid ; Edible Grain ; Eating ; Energy Intake ; Family Characteristics ; Health Promotion ; Iron ; Korea* ; Nutrition Surveys ; Nutritional Status* ; Riboflavin

BACKGROUND: Various olfactory tests have already been proposed in order to clinically assess the olfactory function, for example, UPSIT, T & T olfactometer, CCCRC test, GITU, IV olfaction test. At recent, electro-olfactogram(EOG), olfactorhinometry, olfactory evoked potential, contingent negative variation was tried as the objective olfactory test. OBJECTIVES: We use the functional imaging of MRI which affords the potential for exploring regional pathophysiologic change in living brain as an olfactory function test. MATERIALS AND METHODS: Functional MRI scans of the brain were performed on 5 healthy subjects and 3 patients with olfactory dysfunction. 2 of the patients were diagnosed Parkinson's disease and the other one had basal skull fracture. Then, all subjects were performed CCCRC test. RESULT: 6 of 8 subjects showed significant region of activation in olfactory bulb and tract. Additional region of activation were also observed in amygdala and parahippocampus. Average activation ratio was 3.42+/-2.37%. CONCLUSION: These studies indicate that functional MRI have many limitations but it may be used to evaluate olfactory dysfunction and predict prognosis.
Amygdala ; Brain ; Contingent Negative Variation ; Echo-Planar Imaging* ; Evoked Potentials ; Humans ; Magnetic Resonance Imaging* ; Olfactory Bulb ; Parkinson Disease ; Prognosis ; Skull Fractures ; Smell