1.Efficacy of Topical Hemostatic Powder on Hemorrhagic Complications After Transrectal Prostate Biopsy: A Randomized Controlled Trial
Jung Hoon KIM ; Yong Seong LEE ; In Ho CHANG ; Tuan Thanh NGUYEN ; Se Young CHOI
Journal of Urologic Oncology 2026;24(1):13-20
Purpose:
Topical hemostatic powders may help limit blood loss when applied to a wound early in the course of bleeding. This study evaluated the effectiveness and safety of a hemostatic powder composed of carboxymethyl starch and calcium ions for reducing hemorrhagic complications (specifically hemoglobin loss) after transrectal prostate biopsy.
Materials and Methods:
In this randomized controlled trial, 95 patients undergoing transrectal prostate biopsy received either hemostatic powder with povidone-iodine–soaked gauze or povidone-iodine–soaked gauze alone. The primary outcome was hemoglobin level measured before biopsy and 1 day after biopsy. Secondary outcomes included the incidence of hematuria, hematochezia, infection, and other complications.
Results:
Postbiopsy hemoglobin levels did not differ significantly between the control (12.3±1.6 g/dL) and experimental (12.2±1.8 g/dL) groups (p=0.872). In both groups, hemoglobin level decreased significantly from 13.1±1.9 g/dL before biopsy to 12.2±1.8 g/dL after biopsy (p<0.001). Hematuria occurred in 95.1% of the experimental group and 87.2% of the control group (p=0.389). The incidence of hematochezia was significantly lower in the experimental group (18.8%) than in the control group (59.6%) (p<0.001). No significant differences were observed in other complications, including infection, urinary retention, and transfusion requirement. No severe adverse events were reported in either group.
Conclusion
Application of the hemostatic powder did not prevent postbiopsy hemoglobin decline; however, it significantly reduced the incidence of hematochezia. The procedure appeared safe in this trial, although further studies are needed to identify more effective strategies to prevent cumulative hemoglobin loss after transrectal prostate biopsy.
2.Characteristics and trends of severe/critical COVID-19cases in the Republic of Korea (January 2020 to August 2023)
Se-Jin JEONG ; Shin Young PARK ; Boyeong RYU ; Misuk AN ; Jin-Hwan JEON ; So Young CHOI ; Seong-Sun KIM
Osong Public Health and Research Perspectives 2025;16(1):81-88
Objectives:
We analyzed the demographic and clinical characteristics of patients diagnosedwith coronavirus disease 2019 (COVID-19), focusing specifically on severe/critical cases, andassessed the trends and rates of severity and fatality among these patients in the Republic of Korea.
Methods:
Clinical data on patients with COVID-19 from January 20, 2020 to August 30, 2023were collected from the Korea Disease Control and Prevention Agency’s database. We identified patients who progressed to severe/critical conditions and analyzed their demographic and clinical profiles. Severity and fatality rates were calculated and compared annually to track thedisease progression over time.
Results:
During the surveillance period, 34,572,554 COVID-19 cases were confirmed, among whom 38,112 (0.11%) progressed to severe/critical conditions. Most severe/critical cases occurred in individuals aged ≥60 years, with a notable increase in patients aged ≥80 years from 2022.The overall severity rate was 0.19%, with a fatality rate of 0.10%. However, the severity of cases gradually diminished during the study period. In 2022, the severity and fatality rates decreased to 0.14% and 0.09%, respectively. In 2023, while the severity rate remained stable at 0.15%, thefatality rate further decreased to 0.06%. Notably, throughout the study period, individuals aged ≥80 years had a significantly higher severity rate (2.44%), with a fatality rate of 1.75%.
Conclusion
These findings underscore the importance of prioritizing protection and management strategies for older adults and high-risk groups to mitigate the impact ofCOVID-19. Continued surveillance and analysis are essential to effectively control COVID-19 and minimize its burden on public health.
3.Erratum to "Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin" Biomol Ther 32(2), 249-260 (2024)
Hae Ran LEE ; Seong-Min HONG ; Kyohee CHO ; Seon Hyeok KIM ; Eunji KO ; Eunyoo LEE ; Hyun Jin KIM ; Se Yeong JEON ; Seon Gil DO ; Sun Yeou KIM
Biomolecules & Therapeutics 2025;33(2):415-415
4.Erratum to "Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin" Biomol Ther 32(2), 249-260 (2024)
Hae Ran LEE ; Seong-Min HONG ; Kyohee CHO ; Seon Hyeok KIM ; Eunji KO ; Eunyoo LEE ; Hyun Jin KIM ; Se Yeong JEON ; Seon Gil DO ; Sun Yeou KIM
Biomolecules & Therapeutics 2025;33(2):415-415
5.Characteristics and trends of severe/critical COVID-19cases in the Republic of Korea (January 2020 to August 2023)
Se-Jin JEONG ; Shin Young PARK ; Boyeong RYU ; Misuk AN ; Jin-Hwan JEON ; So Young CHOI ; Seong-Sun KIM
Osong Public Health and Research Perspectives 2025;16(1):81-88
Objectives:
We analyzed the demographic and clinical characteristics of patients diagnosedwith coronavirus disease 2019 (COVID-19), focusing specifically on severe/critical cases, andassessed the trends and rates of severity and fatality among these patients in the Republic of Korea.
Methods:
Clinical data on patients with COVID-19 from January 20, 2020 to August 30, 2023were collected from the Korea Disease Control and Prevention Agency’s database. We identified patients who progressed to severe/critical conditions and analyzed their demographic and clinical profiles. Severity and fatality rates were calculated and compared annually to track thedisease progression over time.
Results:
During the surveillance period, 34,572,554 COVID-19 cases were confirmed, among whom 38,112 (0.11%) progressed to severe/critical conditions. Most severe/critical cases occurred in individuals aged ≥60 years, with a notable increase in patients aged ≥80 years from 2022.The overall severity rate was 0.19%, with a fatality rate of 0.10%. However, the severity of cases gradually diminished during the study period. In 2022, the severity and fatality rates decreased to 0.14% and 0.09%, respectively. In 2023, while the severity rate remained stable at 0.15%, thefatality rate further decreased to 0.06%. Notably, throughout the study period, individuals aged ≥80 years had a significantly higher severity rate (2.44%), with a fatality rate of 1.75%.
Conclusion
These findings underscore the importance of prioritizing protection and management strategies for older adults and high-risk groups to mitigate the impact ofCOVID-19. Continued surveillance and analysis are essential to effectively control COVID-19 and minimize its burden on public health.
6.Erratum to "Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin" Biomol Ther 32(2), 249-260 (2024)
Hae Ran LEE ; Seong-Min HONG ; Kyohee CHO ; Seon Hyeok KIM ; Eunji KO ; Eunyoo LEE ; Hyun Jin KIM ; Se Yeong JEON ; Seon Gil DO ; Sun Yeou KIM
Biomolecules & Therapeutics 2025;33(2):415-415
7.Characteristics and trends of severe/critical COVID-19cases in the Republic of Korea (January 2020 to August 2023)
Se-Jin JEONG ; Shin Young PARK ; Boyeong RYU ; Misuk AN ; Jin-Hwan JEON ; So Young CHOI ; Seong-Sun KIM
Osong Public Health and Research Perspectives 2025;16(1):81-88
Objectives:
We analyzed the demographic and clinical characteristics of patients diagnosedwith coronavirus disease 2019 (COVID-19), focusing specifically on severe/critical cases, andassessed the trends and rates of severity and fatality among these patients in the Republic of Korea.
Methods:
Clinical data on patients with COVID-19 from January 20, 2020 to August 30, 2023were collected from the Korea Disease Control and Prevention Agency’s database. We identified patients who progressed to severe/critical conditions and analyzed their demographic and clinical profiles. Severity and fatality rates were calculated and compared annually to track thedisease progression over time.
Results:
During the surveillance period, 34,572,554 COVID-19 cases were confirmed, among whom 38,112 (0.11%) progressed to severe/critical conditions. Most severe/critical cases occurred in individuals aged ≥60 years, with a notable increase in patients aged ≥80 years from 2022.The overall severity rate was 0.19%, with a fatality rate of 0.10%. However, the severity of cases gradually diminished during the study period. In 2022, the severity and fatality rates decreased to 0.14% and 0.09%, respectively. In 2023, while the severity rate remained stable at 0.15%, thefatality rate further decreased to 0.06%. Notably, throughout the study period, individuals aged ≥80 years had a significantly higher severity rate (2.44%), with a fatality rate of 1.75%.
Conclusion
These findings underscore the importance of prioritizing protection and management strategies for older adults and high-risk groups to mitigate the impact ofCOVID-19. Continued surveillance and analysis are essential to effectively control COVID-19 and minimize its burden on public health.
8.Characteristics and trends of severe/critical COVID-19cases in the Republic of Korea (January 2020 to August 2023)
Se-Jin JEONG ; Shin Young PARK ; Boyeong RYU ; Misuk AN ; Jin-Hwan JEON ; So Young CHOI ; Seong-Sun KIM
Osong Public Health and Research Perspectives 2025;16(1):81-88
Objectives:
We analyzed the demographic and clinical characteristics of patients diagnosedwith coronavirus disease 2019 (COVID-19), focusing specifically on severe/critical cases, andassessed the trends and rates of severity and fatality among these patients in the Republic of Korea.
Methods:
Clinical data on patients with COVID-19 from January 20, 2020 to August 30, 2023were collected from the Korea Disease Control and Prevention Agency’s database. We identified patients who progressed to severe/critical conditions and analyzed their demographic and clinical profiles. Severity and fatality rates were calculated and compared annually to track thedisease progression over time.
Results:
During the surveillance period, 34,572,554 COVID-19 cases were confirmed, among whom 38,112 (0.11%) progressed to severe/critical conditions. Most severe/critical cases occurred in individuals aged ≥60 years, with a notable increase in patients aged ≥80 years from 2022.The overall severity rate was 0.19%, with a fatality rate of 0.10%. However, the severity of cases gradually diminished during the study period. In 2022, the severity and fatality rates decreased to 0.14% and 0.09%, respectively. In 2023, while the severity rate remained stable at 0.15%, thefatality rate further decreased to 0.06%. Notably, throughout the study period, individuals aged ≥80 years had a significantly higher severity rate (2.44%), with a fatality rate of 1.75%.
Conclusion
These findings underscore the importance of prioritizing protection and management strategies for older adults and high-risk groups to mitigate the impact ofCOVID-19. Continued surveillance and analysis are essential to effectively control COVID-19 and minimize its burden on public health.
9.Characteristics and trends of severe/critical COVID-19cases in the Republic of Korea (January 2020 to August 2023)
Se-Jin JEONG ; Shin Young PARK ; Boyeong RYU ; Misuk AN ; Jin-Hwan JEON ; So Young CHOI ; Seong-Sun KIM
Osong Public Health and Research Perspectives 2025;16(1):81-88
Objectives:
We analyzed the demographic and clinical characteristics of patients diagnosedwith coronavirus disease 2019 (COVID-19), focusing specifically on severe/critical cases, andassessed the trends and rates of severity and fatality among these patients in the Republic of Korea.
Methods:
Clinical data on patients with COVID-19 from January 20, 2020 to August 30, 2023were collected from the Korea Disease Control and Prevention Agency’s database. We identified patients who progressed to severe/critical conditions and analyzed their demographic and clinical profiles. Severity and fatality rates were calculated and compared annually to track thedisease progression over time.
Results:
During the surveillance period, 34,572,554 COVID-19 cases were confirmed, among whom 38,112 (0.11%) progressed to severe/critical conditions. Most severe/critical cases occurred in individuals aged ≥60 years, with a notable increase in patients aged ≥80 years from 2022.The overall severity rate was 0.19%, with a fatality rate of 0.10%. However, the severity of cases gradually diminished during the study period. In 2022, the severity and fatality rates decreased to 0.14% and 0.09%, respectively. In 2023, while the severity rate remained stable at 0.15%, thefatality rate further decreased to 0.06%. Notably, throughout the study period, individuals aged ≥80 years had a significantly higher severity rate (2.44%), with a fatality rate of 1.75%.
Conclusion
These findings underscore the importance of prioritizing protection and management strategies for older adults and high-risk groups to mitigate the impact ofCOVID-19. Continued surveillance and analysis are essential to effectively control COVID-19 and minimize its burden on public health.
10.Ghost Surgeries in South Korea: Variations in Practice and the Need for Clear Guidelines in Resident Surgical Training
Seong Joon CHO ; Se-Ran YANG ; Semin RYU ; Sung-Min PARK
Korean Journal of Medical Ethics 2025;28(2):103-123
This article examines the problem of ghost surgeries in South Korea, which gained national attention following the death of Kwon Dae-hee and led to revisions in the Medical Service Act, including a government mandate for video surveillance in operating rooms. While ghost surgeries have been discussed in legal and academic circles, there has been a lack of analysis from the perspective of actual clinical practice. In South Korea, ghost surgeries vary widely depending on the type of hospital, the person replacing the primary surgeon, and the underlying motivation. In teaching hospitals, surgeries performed by residents or fellows during training can be misinterpreted as ghost surgeries, creating a legal and ethical gray area. Despite stricter training regulations, there are still no clear, standardized guidelines for surgical education. Accordingly, this article argues that the relevant authorities—such as the Ministry of Health and Welfare, surgical societies, and medical education institutions—should examine international models and develop clear principles for resident and fellow participation in surgery. This would help ensure informed patient consent, protect medical trainees, promote ethical practices, and ultimately contribute to greater transparency, enhanced surgical education, and a safer healthcare environment for both patients and providers.

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