Background: Workplace loneliness affects employees’ emotional distress and job performance yet validated measurement tools for Korean workers remain limited. This study aims to translate and validate the Loneliness at Work Scale (LAWS) into Korean. Methods: LAWS was translated according to international guidelines as follows: forward translation, reconciliation, back translation and review, and cognitive debriefing. For validation, 1,000 full-time Korean employees proportionally distributed across sex, age, and occupational type were surveyed in November 2024 with a four-week follow-up (N = 200). Internal consistency and test—retest reliability were examined. The validity of the measure was tested by correlational analyses and confirmatory factor analysis. Results: LAWS-K demonstrated excellent internal consistency (Cronbach α overall = 0.936, emotional deprivation = 0.933, social companionship = 0.902) and satisfactory test—retest reliability (r = 0.780).The confirmatory factor analysis revealed that the revised two-factor model provided the best fit (comparative fit index = 0.916, Tucker—Lewis index = 0.897, root mean square error of approximation = 0.126, standardized root mean square residual = 0.045). Correlations with the SingleItem Workplace Loneliness Question (r = 0.612) and the Three-Item Loneliness Scale at Work (r = 0.682) demonstrated strong criterion validity. Correlations with occupational stress (r = 0.531), psychological distress (r = 0.543), work performance (r = -0.337), engagement (r = -0.462), and wellbeing (r = -0.490) supported convergent validity. Conclusion LAWS-K adapted for the Republic of Korea demonstrated robust reliability and validity. It provides Korean researchers and practitioners with a validated tool for assessing workplace loneliness, enabling targeted interventions and research initiatives to address this occupational health concern.

Purpose: Nonneurogenic chronic urinary retention is an uncommon problem in young female individuals, and a well characterised causes is Fowler syndrome (primary disorder of urethral sphincter relaxation). Intermittent catheterisation is often challenging, and gold standard treatment sacral neuromodulation is not widely available. Urethral sphincter botulinum toxin injection has been shown to be effective cross-sectionally, however little is known about long-term outcomes. Methods: Female individuals presenting with urinary retention due to Fowler syndrome were reviewed retrospectively from a single tertiary referral centre over an 11-year period (2010–2021). One hundred units of onabotulinum toxin A (BoTX-A) was injected into the striated urethral sphincter in a divided dose by the periurethral approach. Efficacy and side effects were assessed 4 weeks after injection. Results: Thirty-three female individuals with a mean age of 40.1±14.1 years received 165 unique urethral sphincter BoTX-A injections over 11 years. Nineteen individuals (57.6%) presented in acute urinary retention, and 28 (84.8%) were reliant on catheterisation. Twenty-one individuals (64%) responded to BoTX-A injections and had a significantly raised baseline maximum urethral closure pressure (MUCP), compared to nonresponders (114.6 cm H2O, P=0.012). Side effects were reported following 19 injections (11.5%) however, were mild and transient. Fifteen individuals received more than 1 botulinum toxin injection (median, 3 injections), with a median interval of 112 days (interquartile range) and efficacy persisted following repeat injections and no safety concerns were seen. Conclusions Sphincter botulinum toxin through the periurethral approach is safe and effective following repeat injections, and offers a low-cost, minimally invasive alternative to managing female chronic urinary retention due to Fowler syndrome, particularly when there was a high baseline MUCP.

The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research(NIDCR). Discussion topics included model organisms, stem cells/cell lines, and tissues/3D cell culture/organoids. Scientists from a number of disciplines, representing institutions from across the United States, gathered to discuss advances in our understanding of enamel,as well as future directions for the field.