1.HPV vaccination status and effectiveness in Korean women with HPV16/18 infection (2010–2021):a retrospective study
Yoo Jin NA ; Oeuk JEONG ; Jaehyun SEONG ; JeongGyu LEE ; So Young LEE ; Sooyoung HUR ; Sangmi RYOU
Journal of Gynecologic Oncology 2024;35(5):e56-
Objective:
To evaluate human papillomavirus (HPV) vaccine effectiveness in a cohort of Korean women infected with HPV.
Methods:
From 2010 to 2021, Korean women aged 20–60 years who diagnosed HPV-positive atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion were recruited from 6 hospitals. HPV vaccine effectiveness was estimated by observing the differences in pathological and clinical information and experimental results— prevalence, viral load (VL), physical state (PS), and HPV16/18 infection duration—between the vaccinated and unvaccinated groups.
Results:
HPV16/18 prevalence declined from 18.5% to 11.8% as vaccination rates increased from 14.3% to 60.7% in the 1,757 registered cohort women. DNA analysis from 96 samples collected from the participants, indicated that HPV vaccination reduced HPV16 VL by 6 times and increased E2/E6 ratio for both HPV16 and HPV18 by 1.4 and 5 times, respectively. The HPV16 infection rate—lasting more than 18 months from 31.0% to 21.6%—and the HPV18 infection rate—lasting more than 12 and less than 24 months from 35.5% to 21.1%—were reduced by vaccination. We found VL and the infection duration to be directly proportional.Moreover, HPV vaccination reduced not only the VL to 1/4 in both the persistence and clearance groups but also the persistence rate from 90% (27/30) to 70.6% (12/17) in HPV16.
Conclusion
HPV vaccination reduced the prevalence and duration of infection and kept the PS in an episomal form for both HPV16 and HPV18. The tendency of persistence VL to be higher than clearance in the unvaccinated group implies that the vaccine’s effect of reducing VL in HPV16 may lower the risk of progression to cervical cancer by shortening the infection duration.
2.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
3.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
4.HPV vaccination status and effectiveness in Korean women with HPV16/18 infection (2010–2021):a retrospective study
Yoo Jin NA ; Oeuk JEONG ; Jaehyun SEONG ; JeongGyu LEE ; So Young LEE ; Sooyoung HUR ; Sangmi RYOU
Journal of Gynecologic Oncology 2024;35(5):e56-
Objective:
To evaluate human papillomavirus (HPV) vaccine effectiveness in a cohort of Korean women infected with HPV.
Methods:
From 2010 to 2021, Korean women aged 20–60 years who diagnosed HPV-positive atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion were recruited from 6 hospitals. HPV vaccine effectiveness was estimated by observing the differences in pathological and clinical information and experimental results— prevalence, viral load (VL), physical state (PS), and HPV16/18 infection duration—between the vaccinated and unvaccinated groups.
Results:
HPV16/18 prevalence declined from 18.5% to 11.8% as vaccination rates increased from 14.3% to 60.7% in the 1,757 registered cohort women. DNA analysis from 96 samples collected from the participants, indicated that HPV vaccination reduced HPV16 VL by 6 times and increased E2/E6 ratio for both HPV16 and HPV18 by 1.4 and 5 times, respectively. The HPV16 infection rate—lasting more than 18 months from 31.0% to 21.6%—and the HPV18 infection rate—lasting more than 12 and less than 24 months from 35.5% to 21.1%—were reduced by vaccination. We found VL and the infection duration to be directly proportional.Moreover, HPV vaccination reduced not only the VL to 1/4 in both the persistence and clearance groups but also the persistence rate from 90% (27/30) to 70.6% (12/17) in HPV16.
Conclusion
HPV vaccination reduced the prevalence and duration of infection and kept the PS in an episomal form for both HPV16 and HPV18. The tendency of persistence VL to be higher than clearance in the unvaccinated group implies that the vaccine’s effect of reducing VL in HPV16 may lower the risk of progression to cervical cancer by shortening the infection duration.
5.Effects of Information and Communication Technology Use on the Executive Function of Older Adults without Dementia: A Longitudinal Fixed-Effect Analysis
Hamin LEE ; Sangmi PARK ; Seungho HAN ; Hyeon Dong LEE ; Ickpyo HONG ; Hae Yean PARK
Annals of Geriatric Medicine and Research 2024;28(4):445-452
Background:
Impaired executive function is common in older adults. This study examined the causal relationship between the use of information and communication technology (ICT) and executive function in older adults over time.Method: This study performed a secondary analysis of data from four waves (2016–2019) of the National Health and Aging Trends Study. A fixed-effect analysis was conducted to examine the effects of ICT on the executive function of older adults without dementia aged ≥65 years. This study analyzed data from 3,334 respondents.
Results:
We observed significant positive effects of ICT use on executive function over time (standardized β=0.043–0.045; 95% confidence interval, 0.001–0.043; p<0.05).
Conclusion
The current findings support the use of ICT as a protective approach to prevent decline in executive function in community-dwelling older adults.
6.HPV vaccination status and effectiveness in Korean women with HPV16/18 infection (2010–2021):a retrospective study
Yoo Jin NA ; Oeuk JEONG ; Jaehyun SEONG ; JeongGyu LEE ; So Young LEE ; Sooyoung HUR ; Sangmi RYOU
Journal of Gynecologic Oncology 2024;35(5):e56-
Objective:
To evaluate human papillomavirus (HPV) vaccine effectiveness in a cohort of Korean women infected with HPV.
Methods:
From 2010 to 2021, Korean women aged 20–60 years who diagnosed HPV-positive atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion were recruited from 6 hospitals. HPV vaccine effectiveness was estimated by observing the differences in pathological and clinical information and experimental results— prevalence, viral load (VL), physical state (PS), and HPV16/18 infection duration—between the vaccinated and unvaccinated groups.
Results:
HPV16/18 prevalence declined from 18.5% to 11.8% as vaccination rates increased from 14.3% to 60.7% in the 1,757 registered cohort women. DNA analysis from 96 samples collected from the participants, indicated that HPV vaccination reduced HPV16 VL by 6 times and increased E2/E6 ratio for both HPV16 and HPV18 by 1.4 and 5 times, respectively. The HPV16 infection rate—lasting more than 18 months from 31.0% to 21.6%—and the HPV18 infection rate—lasting more than 12 and less than 24 months from 35.5% to 21.1%—were reduced by vaccination. We found VL and the infection duration to be directly proportional.Moreover, HPV vaccination reduced not only the VL to 1/4 in both the persistence and clearance groups but also the persistence rate from 90% (27/30) to 70.6% (12/17) in HPV16.
Conclusion
HPV vaccination reduced the prevalence and duration of infection and kept the PS in an episomal form for both HPV16 and HPV18. The tendency of persistence VL to be higher than clearance in the unvaccinated group implies that the vaccine’s effect of reducing VL in HPV16 may lower the risk of progression to cervical cancer by shortening the infection duration.
7.Exploring 40 years of Korean medical education conference themes
Do-Hwan KIM ; Sangmi Teresa LEE ; Young-Mee LEE ; Sanghee YEO
Korean Journal of Medical Education 2024;36(2):131-136
Purpose:
The Korean Society of Medical Education (KSME) was founded in 1983 and celebrated its 40th anniversary in 2023. This study examines the evolution of topics discussed at KSME conferences from 1971 through 2023, highlighting shifts in the focus of medical education.
Methods:
We analyzed 90 KSME conferences over 5 decades (1970s, 1980s, 1990s, 2000s, and 2010s), categorizing the topics into three eras based on emerging themes and continuity.
Results:
Consequently, 37 topics covered at the conference were categorized. Ten topics continuously appeared from the 1970s to the 2010s, including future directions of medical education, teaching methods, faculty development, and curriculum. The topics from the 1970s to the 1990s included 14 areas, such as medical education evaluation, non-undergraduate curriculum, community-related, and research. Thirteen new topics emerged after the 2000s, such as social accountability, student support, professionalism, and quality improvements. The most common topics under innovations in medical education, a case of curriculum innovation at universities that began after 2000, were clinical clerkship, curriculum development, and medical humanities.
Conclusion
KSME’s selection of conference topics has been strategically aligned with societal needs and the evolving landscape of medical education. Future topics should continue to address relevant societal and educational challenges.
8.The Past, Present, and Future of Interprofessional Education in Medical Education in South Korea
Yon Chul PARK ; Sangmi T. LEE ; Kyung Hye PARK
Korean Medical Education Review 2024;26(2):83-92
Interprofessional education (IPE) fosters knowledge, skills, and attitudes related to interprofessional collaboration (IPC) for safe, quality patient care. In recent years, the importance of IPC has extended beyond the medical field to local community settings. However, IPE has only recently been introduced and has yet to become widespread. This study reviews the origin and development of IPE in Korean medical education by comparing it with established models in other countries that provide useful insights into future directions for IPE in Korea. Dedicated institutions led the IPE effort in other countries; however, IPE initiatives in Korea were mainly driven by individual professors’ and medical schools’ interest and commitment, without structural support systems. An important finding of this study is that the lack of awareness and organizational support within the medical education community resulted in the absence of a mandatory curriculum for IPE, as it was omitted from the accreditation standards. For more organized adoption and implementation of IPE in Korea, this study suggests the need to widely communicate the importance of IPE to the medical community and the public. It is also imperative to establish leadership capable of guiding IPE, share materials through trusted institutions with IPE experience, and include IPE in the accreditation standards. These steps are essential for actively implementing IPE and meeting societal healthcare needs in Korea.
9.Analysis of the degree of social accountability in accreditation standards for basic medical education
Korean Medical Education Review 2023;25(3):273-284
According to the World Health Organization, for medical schools to fulfill their obligation of social accountability, it is necessary for medical education, research, and service areas to ref lect the healthcare system’s relevance, quality, cost-effectiveness, and equity. This study utilized Boelen and Heck’s (1995) social accountability grid model to analyze the degree to which the Accreditation Standards of Korean Institute of Medical Education and Evaluation 2019 (ASK2019) standards apply the World Federation for Medical Education’s (WFME) standards. The social accountability characteristics of the former were compared to those of the WFME, the Liaison Committee on Medical Education, and the Australian Medical Council. Experts with experience and certification in medical education and evaluation classified the ASK2019 standards according to the grid model, evaluated social accountability perspectives, and categorized them according to the process, content, and outcome. Of the 92 standards, 61 (66.30%) were selected as social accountability standards; these encompassed all areas. There was a particular focus on outcome-related areas, such as “mission and outcomes,” “student assessment,” “educational evaluation,” and “continuous improvement.” Education and quality were the most common (33, 54.11%), followed by 18 standards related to education and relevance. However, the standards on cost effectiveness and equity corresponding to education, research, and service were significantly insufficient. As a result of classification using a logic model, many criteria were incorporated into the process, producing results similar to those of international accreditation institutions. Therefore, to fulfill medical schools’ social accountability, it is necessary to develop cost effectiveness and equity standards with reference to grid models and expand them beyond education to include research and service areas. Developing content and outcome standards is also required.
10.Instructional Design for Systems Thinking Education in Health Systems Science
Sejin KIM ; Sangmi T LEE ; Danbi LEE ; Bo Young YOON
Korean Medical Education Review 2023;25(3):212-228
Systems thinking, a linking domain of health systems science (HSS), is an approach that investigates specific problems from a holistic perspective. It supports improving patients’ health, fulfilling their health needs, and anticipating issues that threaten patient safety within the healthcare system. It also helps solve problems through critical thinking and reflection. This study aimed to develop an curriculum on systems thinking, explore the effectiveness of the course, and investigate the applicability of HSS education at individual universities. In this study, the ADDIE (Analysis, Design, Development, Implementation, and Evaluation) model was utilized to design, develop, implement, and evaluate an elective course on systems thinking. In the design process, learning outcomes and goals were developed, and educational content, teaching-learning methods, and student evaluation methods were linked. In the development process, class materials and evaluation materials were prepared. In the implementation process, the course was implemented, and the evaluation process analyzed the results of learning performance and curriculum assessments. The evaluation found the following results. First, the students in the study realized the importance of systems thinking and experienced the need for systems thinking through non-medical and medical situations. Second, the students were very satisfied with the learning activities in the course (mean=4.84), and the results of the self-competence evaluation, conducted before and after the course, also showed a significant improvement. This study confirmed the effectiveness of the elective course, and its results can serve as a reference for developing an HSS curriculum .

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