Objective:To investigate the impact of perceived barriers to cardiac rehabilitation on adherence to cardiac rehabilitation and the mediating effect of cardiac impact denial in elderly patients after percutaneous coronary intervention (PCI) .Methods:This study was a cross-sectional survey. From August 2023 to July 2024, 336 elderly patients with PCI who were discharged from the First Affiliated Hospital of Wenzhou Medical University and needed phaseⅡ cardiac rehabilitation were selected for the study. General Information Questionnaire, Adherence of Cardiac Rehabilitation Assessment Scale in Patients with Coronary Heart Disease (ACRAS-CHD) , Cardiac Rehabilitation Barriers Scale (CRBS) , and Cardiac Denial of Impact Scale (CDIS) were used to survey the patients. Bootstrap method was used to sample 5 000 for mediating effect tests.Results:A total of 336 questionnaires were distributed and 324 valid questionnaires were recovered, with a valid recovery rate of 96.43% (324/336) . Among 324 elderly patients after PCI, ACRAS-CHD score, CRBS score, and CDIS score were (73.19±5.46) , (79.35±6.60) , and (30.57±3.66) , respectively. The direct effect of perceived barriers to cardiac rehabilitation on adherence to cardiac rehabilitation in elderly patients after PCI was -0.368, which accounted for 74.49% (-0.368/-0.494) of the total effect. The mediating effect of cardiac impact denial between perceived barriers to cardiac rehabilitation and adherence to cardiac rehabilitation in elderly patients after PCI was -0.126, which accounted for 25.51% of the total effect (-0.126/-0.494) .Conclusions:Elderly patients after PCI have poor adherence to cardiac rehabilitation. Perceived cardiac rehabilitation barriers reduce cardiac rehabilitation adherence in elderly patients after PCI, and cardiac impact denial exerts a partial mediating effect between perceived cardiac rehabilitation barriers and cardiac rehabilitation adherence.

Objective:To investigate the impact of perceived barriers to cardiac rehabilitation on adherence to cardiac rehabilitation and the mediating effect of cardiac impact denial in elderly patients after percutaneous coronary intervention (PCI) .Methods:This study was a cross-sectional survey. From August 2023 to July 2024, 336 elderly patients with PCI who were discharged from the First Affiliated Hospital of Wenzhou Medical University and needed phaseⅡ cardiac rehabilitation were selected for the study. General Information Questionnaire, Adherence of Cardiac Rehabilitation Assessment Scale in Patients with Coronary Heart Disease (ACRAS-CHD) , Cardiac Rehabilitation Barriers Scale (CRBS) , and Cardiac Denial of Impact Scale (CDIS) were used to survey the patients. Bootstrap method was used to sample 5 000 for mediating effect tests.Results:A total of 336 questionnaires were distributed and 324 valid questionnaires were recovered, with a valid recovery rate of 96.43% (324/336) . Among 324 elderly patients after PCI, ACRAS-CHD score, CRBS score, and CDIS score were (73.19±5.46) , (79.35±6.60) , and (30.57±3.66) , respectively. The direct effect of perceived barriers to cardiac rehabilitation on adherence to cardiac rehabilitation in elderly patients after PCI was -0.368, which accounted for 74.49% (-0.368/-0.494) of the total effect. The mediating effect of cardiac impact denial between perceived barriers to cardiac rehabilitation and adherence to cardiac rehabilitation in elderly patients after PCI was -0.126, which accounted for 25.51% of the total effect (-0.126/-0.494) .Conclusions:Elderly patients after PCI have poor adherence to cardiac rehabilitation. Perceived cardiac rehabilitation barriers reduce cardiac rehabilitation adherence in elderly patients after PCI, and cardiac impact denial exerts a partial mediating effect between perceived cardiac rehabilitation barriers and cardiac rehabilitation adherence.

Objective To evaluate the quality and authenticity of Ophiopogon japonicus in Shengmaiyin,establish ultra performance liquid chromatography tandem mass spectrometry(UPLC-MS/MS)for the determination of three characteristic components(methylophiopogonanone A,liriopeside B and liriope muscari baily saponin C),and provide technical support for drug supervision.Methods Samples were analyzed on a Phenomenex Kinetex F5 C18 column(100 mm×3.0 mm,2.6 μm)in a gradient elution mode with 0.1％formic acid water and-0.1％formic acid acetonitrile as the mobile phase at a flow rate of 0.4 mL/min,the column temperature was 30 ℃,and the injection volume was 1 μL.Mass spectrometer detector,electro spray ion source of positive and negative ions,and multi-reaction monitoring mode were used.Results The linear ranges of methylophiopogonanone A,liriopeside B and liriope muscari baily saponin C were 0.016 7-1.666 0,0.039 7-15.872 0 and 0.022 5～8.988 0 ng(r＞0.999 9),respectively.The average recovery rates of these three components were 85.16％,86.95％and 95.07％,respectively,with RSSDs of 2.65％,1.45％and 1.14％(n=6).The content of methylophiopogonanone A in thirty-eight batches was quite different.Seven batches of liriopeside B or liriope muscari baily saponin C were detected.Conclusion The method is simple and sensitive,and suitable for determining of three characteristic components in Shengmaiyin,which provides references for the quality control of Ophiopogon japonicus in Shengmaiyin.

Objective:To summarize the hotspots and developmental status of non-suicidal self-injury research by clustering and co-occurrence to the literature on non-suicidal self-injury on the basis of Cite Space, and in order to provide references for future research and intervention.Methods:Non-suicidal self-injury literature included in the Web of science core collection from January 1975 to August 2020 was searched, and the included literature was visualized and analyzed using Cite Space 5.5.R2 knowledge mapping software.Results:A total of 974 articles were retrieved, and the number of articles published showed an increasing trend year by year, mostly in developed countries. The country with the highest cumulative number of articles was the United States, with a total of 412 articles, and the first organization was Katholieke Univ Leuven, with a total of 42 articles. Key words co-occurrence and clustering showed that the current research focus was on adolescents, suicidal behavior, dialectical behavior therapy, and borderline personality disorder. The most cited literature was by Muehlenkamp.Conclusions:Non-suicidal self-injury research has developed rapidly in recent years. At present, non-suicidal self-injury population, related intervention measures, screening and evaluation tools, Meta-analysis and risk factor analysis are its research frontiers and hot spots.