1.Clinical effect of non-transecting anastomotic lingual mucosal augmentation urethroplasty in the treatment of traumatic urethral stricture
Wenxiong SONG ; Jiemin SI ; Xuxiao YE ; Zuowei LI ; Jianwen HUANG ; Yinglong SA ; Yuemin XU
Chinese Journal of Urology 2025;46(2):119-124
Objective:To investigate the clinical effect of lingual mucosal augmentation urethroplasty with non-transecting urethral cavernous anastomosis in the treatment of traumatic urethral stricture.Methods:The clinical data of 39 patients with traumatic urethral stricture admitted to our clinical center from March 2023 to December 2023 were retrospectively analyzed. Their mean age was (49.7±2.0)years. The cause of urethral injury was pelvic fracture in 32 cases, riding injury in 5 cases, and iatrogenic injury in 2 cases. Suprapubic vesicostomy tube was indwelled before operation in 39 cases. There was 1 case with hypospadias and 1 case with urethral false passage. 9 patients had urethral dilatation before surgery, 5 had internal urethrotomy operation, 5 had urethroplasty, and 22 had no history of urethral surgery. The International Erectile Function Index (IIEF-5)score of 39 cases last 1 month before surgery was collected and classified.In which, the IIEF-5 score of 19 cases with no or mild erectile dysfunction was median 20 (18, 23)points, the MSHQ-Ejd score was median 16 (11, 19)points, and the number of effective erections was median 4(3, 5)times on the NPT. And in which, the IIEF-5 score of 20 cases with moderate to severe erectile dysfunction was median 10 (3, 14)points, the MSHQ-Ejd score was median 3(1, 7)points, and the number of effective erections was median 1(0, 2)times on the NPT. All 39 cases underwent non-transecting anastomotic lingual mucosal augmentation urethroplasty. The central tendon of the perineum and the ventral side of the bulbar urethra were preserved through perineal approach. The dorsal side of the urethra was mobilized and through the dorsal side of the urethra, the scar of the urethra was enucleated along the mucosa of the urethra. Then the ventral mucosa of the urethra was anastomosed end to end and the dorsal urethra was repaired by lingual mucosa transplantation. The Clavien-Dindo complication grading system was performed. The catheter was removed 4 weeks after operation, and urine flow rate was recorded 1 month after extubation. IIEF-5 score, MSHQ-Ejd score and NPT were recorded 6 months after operation.Results:The mean operation time of 39 cases was (118.0±18.3)min. 39 cases were followed up for median 8.0(6.0, 10.0)months. The Q max ≥15 ml/s in 24 cases. The Q max <15ml/s in 13 cases, of which, the Q max ≥15 ml/s after 1 internal urethrotomy operation in 10 cases and Q max≥15 ml/s after 2 internal urethrotomy operations in 3 cases. 2 cases were still failed to urinate and Q max≥15 ml/s after end-to-end urethral anastomosis. All 39 cases’ Clavien-Dindo complications were graded Ⅰ.Of the 19 cases with no or mild erectile dysfunction, the IIEF-5 score was median 20(17, 23)points, the MSHQ-Ejd score was median 16(11, 19)points, and the number of effective erections was median 4(3, 4)times on the NPT postoperatively, all were not significantly different from those before operation ( P> 0.05). Of the 20 cases with moderate and severe erectile dysfunction, the IIEF-5 score was median 9(4, 13)points, the MSHQ-Ejd score was median 4(2, 7)points, and the number of effective erections was median 1(0, 2)times on the NPT postoperatively, and all were not significantly different from those before operation ( P>0.05). Conclusions:Non-transecting anastomotic lingual mucosal augmentation urethroplasty is a reliable surgical method with few complications for traumatic urethral stricture. Moreover, the operation has little effect on the sexual function of patients.
2.Management strategies for vesicovaginal fistula following cervical cancer radiotherapy in women
Jiemin SI ; Weidong ZHU ; Ranxing YANG ; Lujie SONG ; Chongrui JIN ; Jianwen HUANG ; Xuxiao YE ; Zuowei LI ; Wenxiong SONG ; Qiang FU ; Yinglong SA
Chinese Journal of Urology 2025;46(8):587-592
Objective:To investigate the treatment strategies for vesicovaginal fistula(VVF)in women following cervical cancer radiotherapy.Methods:A retrospective analysis was performed on the clinical data of 33 female patients with post-radiotherapy VVF after cervical cancer treatment at Shanghai Sixth People’s Hospital between January 2020 and June 2024. The patients were categorized into three groups based on surgical approaches:Group A(11 patients):Underwent prone-position VVF repair. Mean age:(50.0±9.6)years;mean radiotherapy sessions:(22.6±2.2). All had simple VVF without concurrent intestinal or surrounding soft-tissue fistulas. Among them,1 patient previously received laparoscopic VVF repair,1 transvaginal VVF repair,and 2 gracilis muscle flap packing for VVF repair. One month prior to surgery,the average daily usage of urine pads was 16.7(12.8,25.7)pieces,and the quality of life(QOL)score stood at 4.0(4.0,5.0)points. Preoperative cystoscopy revealed that 8 cases had fistulas located in the trigonal region of the bladder,while 3 cases had fistulas on the posterior bladder wall. The diameter of the fistula openings,measured under a microscope,was 1.2(0.8,1.6)cm. Based on the Goh classification criteria for vesicovaginal fistulas,this group included 3 cases of type 1,4 cases of type 2,2 cases of type 3,and 2 cases of type 4;7 cases of type A and 4 cases of type B;as well as 3 cases of typeⅠ,7 cases of type Ⅱ,and 1 case of type Ⅲ.Group B(20 patients):Underwent gracilis muscle flap packing for VVF repair. Mean age:(58.6±8.8)years;mean radiotherapy sessions:(29.8±3.9). Three patients had concurrent rectovaginal fistulas and received colostomy for fecal diversion. History of previous interventions:3 had laparoscopic VVF repair,4 transvaginal VVF repair,and 1 both transvaginal and laparoscopic VVF repair. One month prior to surgery,the average daily usage of urine pads was 19.7(15.8,27.7)pieces,and the QOL score stood at 5.0(5.0,6.0)points. Preoperative cystoscopy revealed that 13 cases had fistulas located in the trigonal region of the bladder,while 7 cases had fistulas on the posterior bladder wall. The diameter of the fistula openings,measured under a microscope,was 1.8(1.0,3.2)cm. Based on the Goh classification criteria for vesicovaginal fistulas,this group included 4 cases of type 1,9 cases of type 2,3 cases of type 3,and 4 cases of type 4;6 cases of type A,11 cases of type B and 3 cases of type C;as well as 1 cases of type Ⅱ,and 19 case of type Ⅲ. Group C(2 patients):Underwent ureterocutaneous diversion. Ages:67 and 73 years;radiotherapy sessions:51 and 60,respectively. Both had concurrent rectovaginal fistulas and bladder soft-tissue fistulas. The patient presented with recurrent thigh abscesses accompanied by fever. One month prior to surgery,the daily usage of urine pads was 29 and 23 pieces,respectively,and the QOL score was 6 points. Cystoscopic examination revealed that the vesicovaginal fistulas were located in the trigone of the bladder,with diameters of 3 cm and 4 cm,respectively. Additionally,partial defects were noted in the ventral wall of the urethra,while no bladder soft tissue fistulas were detected. According to the Goh classification for vesicovaginal fistulas,both cases were categorized as type 4,type C,and type Ⅲ. For Groups A and B,urinary catheters were indwelled for 3 weeks postoperatively,then removed to assess spontaneous urination and incontinence. QOL was evaluated,with a minimum 6-month follow-up. For confirmed postoperative VVF recurrence,re-repair was performed 3?6 months later based on patient preference. For Group C,double-J stents were placed in the ureters,and stoma bags were applied 3 days postoperatively. Stents were replaced every 1?2 months,with QOL assessment. Successful fistula repair in Groups A and B was defined as the absence of vaginal leakage confirmed by cystoscopy after six months of the procedure with no vaginal leakage. For Group C,surgical success was determined by the resolution of perineal urinary leakage and improvement in QOL.Results:All 33 patients completed surgery successfully. Group A:Follow-up duration:16.3(9.6,24.6)months. Surgical repair succeeded in 7 patients,with unobstructed spontaneous urination and no vaginal incontinence. Four patients had VVF recurrence:2 refused further treatment,and 2 underwent repeat gracilis muscle flap packing. One was successfully repaired,while one recurrence case refused further treatment. Group B:Follow-up duration:17.0(9.5,24.8)months(8?32 months). Thirteen patients restored spontaneous urination without recurrence. Seven had recurrence:5 refused further surgery,and 2 underwent re-repair. One repair succeeded without incontinence,while one recurrence case refused treatment. Group C:Follow-up durations were 6 and 22 months. Perineum remained dry without incontinence(no urine pads needed),and no recurrence of thigh soft-tissue redness/infection occurred. QOL scores were 2 and 3,respectively.Conclusions:Post-radiotherapy VVF in women after cervical cancer presents complex and variable conditions. The primary goal of treatment should be to improve patients’ quality of life. Treatment approaches should be selected based on the complexity of urinary fistulas and local tissue conditions. In general,patients who are younger,have received lower doses of radiation therapy,present with smaller fistula diameters,have well-vascularized and elastic perifistular tissues,and have no concurrent tissue fistulas are candidates for prone-position VVF repair. Patients who do not meet the criteria for transvaginal repair,have a history of at least two previous repair attempts,or have concurrent vaginorectal fistulas require gracilis muscle flap packing for VVF repair. Patients with three or more types of concurrent tissue fistulas,extensive pale and inelastic perifistular tissues,and who are not amenable to repair surgery undergo ureterocutaneous diversion.
3.An anteromedial approach of the hip for Pipkin Ⅰ and Ⅱ femoral head fractures: an imaging and anatomical study
Junjie GUAN ; Chenjun LIU ; Zhiyuan FAN ; Xin QI ; Ning XU ; Weichao YANG ; Hui SUN ; Sa SONG ; Wei ZHANG
Chinese Journal of Orthopaedic Trauma 2025;27(3):210-215
Objective:To explore a new surgical approach [anteromedial approach of the hip (AMA)] for Pipkin Ⅰ and Ⅱ femoral head fractures through an imaging and anatomical study.Methods:The hip imaging data were collected of the 38 patients who had undergone lower limb CT angiography for open tibiofibular fractures at Department of Orthopaedics, The Sixth People’s Hospital, School of Medicine, Shanghai Jiao Tong University from June 2023 to January 2024. There were 20 males aged (40.9±3.5) years and 18 females aged (41.5±3.3) years. The origins and shapes of the femoral artery and its main branches were observed. The distances between the femoral head and the femoral artery, the medial femoral circumflex artery, and the lateral femoral circumflex artery were measured. Four fresh adult cadavers were collected, including 2 males and 2 females. Their ages of death were 56, 65, 72 and 78 years old, respectively. An incision was made along the axis of the limb at the midpoint of the inguinal ligament at the 4 fresh cadavers. After the femoral head was exposed through the gap between the femoral artery and the femoral nerve, the range of the femoral head exposed was marked.Results:The femoral artery ran along the anteromedial side of the femoral head. The shortest distance between the medial femoral circumflex artery and the femoral head was (13.1±5.7) mm, and the shortest distance between the origin of the lateral femoral circumflex artery and the femoral head (21.6±8.6) mm. On the lateral view of CT angiography, the distance between the femoral artery and the femoral head was (20.6±4.9) mm at the level of the apex of greater trochanter. Gross observation on the cadavers found only small branches of vessels between the femoral artery and the femoral nerve. After the femoral artery and femoral nerve were respectively pulled medially and laterally, the anterior-inferior part of the femoral head was exposed directly by pulling the muscles to open the joint capsule. The exposure range of the femoral head was further expanded through internal and external rotation of the hip joint under traction. The anatomical gap between the femoral artery and the femoral nerve was named the AMA.Conclusion:AMA utilizes the potential gap between the femoral artery and the femoral nerve, providing a new surgical approach for exposure and fixation of Pipkin type Ⅰ and Ⅱ femoral head fractures.
4.Scoping review of assessment tools of transition readiness in adolescents with chronic illnesses
Sa WANG ; Lina BAI ; Dandan ZHANG ; Yuwei LI ; Caicai QIAO ; Weiting SONG ; Huali MIAO
Chinese Journal of Practical Nursing 2025;41(3):234-241
Objective:To summarize domestic and foreign transitional readiness assessment tools for adolescents with chronic diseases and analyze the current status of their application in the clinic, so as to provide references for healthcare professionals to select appropriate tools.Methods:China National Knowledge Infrastructure, Wanfang Data, VIP and China Biomedical Literature Database, PubMed, Web of Science, Embase, Medline, CINAHL, Cochrane Library and scholar.google.com were searched for literature related to the assessment tools of transition readiness in adolescents with chronic illnesses from inception to March 29, 2024. Two researchers independently screened the literature and extracted the data.Results:A total of 491 articles were initially retrieved and 24 were included, involving a total of 8 transitional readiness assessment tools for adolescents with chronic diseases, including the Transition Readiness Assessment questionnaire, the University of North Carolina TRxANSITION Scale, Am I ON TRAC for adult care? Questionnaire, Transition Questionnaire, Self-Management and Transition to Adulthood with Rx=Treatment Questionnaire, Good 2 Go Questionnaire, State Assessment Questionnaire for Transition, and Self-assessment Scale of Transition Readiness for Adolescents. The Transition Readiness Assessment questionnaire and Self-Management and Transition to Adulthood with Rx=Treatment Questionnaire have good reliability and validity, comprehensive evaluation, wide applicability, simple use, and are suitable for clinical use.Conclusions:The quality of existing tools for assessing transitional readiness of adolescents with chronic diseases is mixed. The Transition Readiness Assessment questionnaire and Self-Management and Transition to Adulthood with Rx=Treatment Questionnaire are more appropriate options in the clinic, but they still need to be improved. Future studies need to continue to introduce tools to assess transitional readiness for chronic diseases in adolescents and develop localized assessment tools.
5.Complication profiles of different surgical repair techniques for donor sites following lingual mucosa graft harvesting: a comparative study
Song LI ; Jiemin SI ; Xuxiao XIE ; Wenxiong SONG ; Zuowei LI ; Fangmin CHEN ; Kai LI ; Yinglong SA
Chinese Journal of Urology 2025;46(8):611-616
Objective:To compare postoperative complications between acellular dermal matrix(ADM)and direct suture for tongue mucosa defect repair during lingual mucosa urethroplasty.Methods:A retrospective analysis was conducted on 106 patients with anterior urethral stricture who underwent lingual mucosal urethroplasty at the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from July 2022 to July 2024. According to the needs of urethral reconstruction,lingual mucosa was harvested(graft length 0.5 cm longer than the stricture length). Using an instrumental variable method based on the surgeon’s preference,the tongue wound was repaired either with ADM or direct suture. The ADM group included 56 patients,aged(46.2±18.7)years;diabetes in 8 cases(14.3%),hypertension in 15 cases(26.8%),cardiopulmonary dysfunction in 3 cases(5.3%);stricture location:penile segment in 44 cases(78.6%),penoscrotal junction in 12 cases(21.4%);etiology:lichen sclerosus in 8 cases(14.3%),urethritis in 8 cases(14.3%),trauma in 24 cases(42.9%),and re-stricture after hypospadias surgery in 16 cases(28.6%);maximum urinary flow rate(5.8±2.9)ml/s;graft length(4.02±1.72)cm. The direct suture group included 50 patients,aged(45.8±19.2)years;diabetes in 6 cases(12.0%),hypertension in 12 cases(24.0%),cardiopulmonary dysfunction in 2 cases(4.0%);etiology:lichen sclerosus in 6 cases(12.0%),urethritis in 8 cases(16.0%),trauma in 25 cases(50.0%),and re-stricture after hypospadias surgery in 11 cases(22%);stricture location:penile segment in 36 cases(72.0%),penoscrotal junction in 14 cases(28.0%);maximum urinary flow rate(6.2±3.1)ml/s;graft length(4.18±1.68)cm. There were no statistically significant differences in the above baseline characteristics between the two groups( P>0.05).ADM group after electrocautery hemostasis,an ADM patch tailored to the wound size was used to cover the donor site. The edges of the ADM were overlapped with the wound margin and sutured to the submucosal layer using interrupted 4-0 polyglactin sutures. Direct suture group after electrocautery hemostasis,the wound was stretched into a diamond shape and closed in layers by suturing the mucosal layer down to the muscle layer using interrupted 4-0 polyglactin sutures. The primary outcome measures were postoperative tongue complications including hemorrhage,hematoma,and infection(Clavien-Dindo classification). Secondary outcomes included VAS pain scores,functional recovery(difficulty drinking,difficulty eating,speech impairment,limited mouth opening),and sensory recovery(sensory disturbance,taste disturbance). Results:The follow-up period ranged from 6 to 24 months,with a mean of 9.2 months. The 6-month follow-up rate was 100%. No Clavien-Dindo grade Ⅲ or higher complications(hemorrhage,hematoma,infection)occurred by the end of follow-up. Regarding secondary outcomes,the VAS pain score on postoperative day 1 was significantly better in the ADM group than in the suture group[0(0,3)vs. 2(0,3),P=0.013].Functional impact:The incidence of difficulty drinking[24 cases(42.9%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 21 cases(42.0%)],difficulty eating[20 cases(35.7%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 27 cases(54.0%)],and speech impairment[20 cases(35.7%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 27 cases(54.0%)]on postoperative day 1,day 7,and within the first month,respectively,was significantly lower in the ADM group(all P<0.05). On postoperative day 1 and day 7,the incidence of limited mouth opening was higher in the ADM group[0 cases vs. 6 cases(12.0%),0 cases vs. 6 cases(12.0%)]( P<0.05).Sensory recovery:The incidence of taste disturbance was higher in the ADM group at 7 days[8 cases(14.3%)vs. 0 cases],1 month[8 cases(14.3%)vs. 0 cases],and 3 months[8 cases(14.3%)vs. 0 cases]postoperatively( P<0.05). The incidence of sensory disturbance was higher in the ADM group at 1 day[20 cases(35.7%)vs. 6 cases(12.0%)],7 days[16 cases(28.6%)vs. 6 cases(12.0%)],and 1 month[16 cases(28.6%)vs. 6 cases(12.0%)]postoperatively( P<0.05). Pain scores and complication rates were zero in both groups after 6 months. Conclusions:ADM repair improves early recovery but may increase transient sensory complications. Both methods are safe for clinical application.
6.Efficacy of the transpubic access in the treatment of female urogenital tract injury
Weidong ZHU ; Jiemin SI ; Chongrui JIN ; Wenxiong SONG ; Xuxiao YE ; Lujie SONG ; Qiang FU ; Yinglong SA
Chinese Journal of Urology 2025;46(10):774-777
Objective:To explore the application value of transpubic access on female urogenital tract injury.Methods:A retrospective analysis was conducted on 15 female patients with urogenital tract injury caused by trauma admitted to our department from May 2020 to October 2024,all of whom were complicated urethral stricture or atresia,accompanied by urethrovaginal fistula or vaginorectal fistula. All patients underwent suprapubic vesicostomy before surgery,and 1 case underwent sigmoidostomy simultaneously. The mean age of the patients was(29.6 ± 3.2)years old,and the course of disease was 6-24 months. Preoperative urethrography and urethroscope showed the location of urethral stenosis,with proximal urethra stricture in 7 cases and distal urethra stricture in 8 cases. The average length of strictures was(2.8±0.2)cm. The urethral ultrasonography,magnetic resonance and CTU examination showed 8 patients were complicated with urethrovaginal fistula,and 1 patient was complicated with vaginorectal fistula. All patients underwent transpubic access and resection of symphysis pubis. According to the specific conditions of urethral stricture,7 of them underwent end-to-end urethral anastomosis,5 cases underwent bladder wall flap urethroplasty,3 cases underwent vulva flap urethroplasty,8 cases underwent urethral vaginal fistula repair,1 case underwent vagino-rectal fistula repair,and 7 cases underwent vaginoplasty during the operation.Results:All the 15 patients underwent successful operation without complication. After the catheter being removed 4 weeks after surgery,2 patients had urgent urinary incontinence and 3 patients had stress urinary incontinence. The bladder neck was reconstructed 3 months after surgery,the symptoms of urinary incontinence improved in 1 case,urinary incontinence remained in 2 cases,and pharmaceutical or physical therapy were continued. Two patients could not urinate normally after the catheter was removed and still carried the vesicostomy tube,waiting for further treatment. The other 8 patients had unobtrusive voiding after extubating,and were followed up for an average of(22.5±3.2)months. There was no recurrence of urinary fistula,and the average maximum urinary flow rate was(22.8±3.2)ml/s.Conclusions:The transpubic approach is a safe and effective way to treat female genital tract injury by different surgical methods according to specific conditions,especially for patients with severe trauma,poor local tissue conditions,complicated urethrovaginal fistula or vagino-rectal fistula.
7.A systematic review of tools for assessing the readiness of patients with chronic diseases aged 10-19 to transition to adulthood
Sa WANG ; Huali MIAO ; Yuwei LI ; Hongwei WANG ; Caicai QIAO ; Weiting SONG
Chinese Journal of Nursing 2025;60(4):469-477
Objective To systematically evaluate the assessment tools of adolescent chronic disease patients'transition readiness to adults at home and abroad,and to provide references for medical personnel to choose appropriate tools.Methods CNKI,Wan Fang Data,CBM,PubMed,Web of Science,Embase and Cochrane were searched for literature related to the assessment tools of transition readiness in adolescents with chronic illnesses to adulthood from inception to August,2024.Literature screening and data extraction of the tools were extracted independently by 2 researchers.At the same time,the criteria for the selection of health measurement tools based on consensus(COSMIN)systematic evaluation guidelines were used to evaluate the inclusion assessment tools,and recommendations were finally formed.Results A total of 29 articles were included,involving 9 universal and 5 specific assessment tools of adolescent chronic illnesses transition readiness.The Transition Readiness Assessment Questionnaire has satisfactory content validity and internal consistency,and it is recommended as Grade A.The Grade C included the Am I ON TRAC for adult care?Questionnaire and the State Assessment Questionnaire for Transition,Epilepsy-specific Transition Readiness Assessment Questionnaire and the Readiness for Adult Care in Rheumatology,while the others are recommended as Grade B.Conclusion There are a variety of tools to assess the transition readiness of adolescents with chronic diseases to adults,and there are few tools suitable for adolescents with chronic diseases in China,with few specific tools.After comprehensive consideration,the Transition Readiness Assessment Questionnaire can be recommended temporarily.
8.Complication profiles of different surgical repair techniques for donor sites following lingual mucosa graft harvesting: a comparative study
Song LI ; Jiemin SI ; Xuxiao XIE ; Wenxiong SONG ; Zuowei LI ; Fangmin CHEN ; Kai LI ; Yinglong SA
Chinese Journal of Urology 2025;46(8):611-616
Objective:To compare postoperative complications between acellular dermal matrix(ADM)and direct suture for tongue mucosa defect repair during lingual mucosa urethroplasty.Methods:A retrospective analysis was conducted on 106 patients with anterior urethral stricture who underwent lingual mucosal urethroplasty at the Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from July 2022 to July 2024. According to the needs of urethral reconstruction,lingual mucosa was harvested(graft length 0.5 cm longer than the stricture length). Using an instrumental variable method based on the surgeon’s preference,the tongue wound was repaired either with ADM or direct suture. The ADM group included 56 patients,aged(46.2±18.7)years;diabetes in 8 cases(14.3%),hypertension in 15 cases(26.8%),cardiopulmonary dysfunction in 3 cases(5.3%);stricture location:penile segment in 44 cases(78.6%),penoscrotal junction in 12 cases(21.4%);etiology:lichen sclerosus in 8 cases(14.3%),urethritis in 8 cases(14.3%),trauma in 24 cases(42.9%),and re-stricture after hypospadias surgery in 16 cases(28.6%);maximum urinary flow rate(5.8±2.9)ml/s;graft length(4.02±1.72)cm. The direct suture group included 50 patients,aged(45.8±19.2)years;diabetes in 6 cases(12.0%),hypertension in 12 cases(24.0%),cardiopulmonary dysfunction in 2 cases(4.0%);etiology:lichen sclerosus in 6 cases(12.0%),urethritis in 8 cases(16.0%),trauma in 25 cases(50.0%),and re-stricture after hypospadias surgery in 11 cases(22%);stricture location:penile segment in 36 cases(72.0%),penoscrotal junction in 14 cases(28.0%);maximum urinary flow rate(6.2±3.1)ml/s;graft length(4.18±1.68)cm. There were no statistically significant differences in the above baseline characteristics between the two groups( P>0.05).ADM group after electrocautery hemostasis,an ADM patch tailored to the wound size was used to cover the donor site. The edges of the ADM were overlapped with the wound margin and sutured to the submucosal layer using interrupted 4-0 polyglactin sutures. Direct suture group after electrocautery hemostasis,the wound was stretched into a diamond shape and closed in layers by suturing the mucosal layer down to the muscle layer using interrupted 4-0 polyglactin sutures. The primary outcome measures were postoperative tongue complications including hemorrhage,hematoma,and infection(Clavien-Dindo classification). Secondary outcomes included VAS pain scores,functional recovery(difficulty drinking,difficulty eating,speech impairment,limited mouth opening),and sensory recovery(sensory disturbance,taste disturbance). Results:The follow-up period ranged from 6 to 24 months,with a mean of 9.2 months. The 6-month follow-up rate was 100%. No Clavien-Dindo grade Ⅲ or higher complications(hemorrhage,hematoma,infection)occurred by the end of follow-up. Regarding secondary outcomes,the VAS pain score on postoperative day 1 was significantly better in the ADM group than in the suture group[0(0,3)vs. 2(0,3),P=0.013].Functional impact:The incidence of difficulty drinking[24 cases(42.9%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 21 cases(42.0%)],difficulty eating[20 cases(35.7%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 27 cases(54.0%)],and speech impairment[20 cases(35.7%)vs. 36 cases(72.0%),16 cases(28.6%)vs. 36 cases(72.0%),8 cases(14.3%)vs. 27 cases(54.0%)]on postoperative day 1,day 7,and within the first month,respectively,was significantly lower in the ADM group(all P<0.05). On postoperative day 1 and day 7,the incidence of limited mouth opening was higher in the ADM group[0 cases vs. 6 cases(12.0%),0 cases vs. 6 cases(12.0%)]( P<0.05).Sensory recovery:The incidence of taste disturbance was higher in the ADM group at 7 days[8 cases(14.3%)vs. 0 cases],1 month[8 cases(14.3%)vs. 0 cases],and 3 months[8 cases(14.3%)vs. 0 cases]postoperatively( P<0.05). The incidence of sensory disturbance was higher in the ADM group at 1 day[20 cases(35.7%)vs. 6 cases(12.0%)],7 days[16 cases(28.6%)vs. 6 cases(12.0%)],and 1 month[16 cases(28.6%)vs. 6 cases(12.0%)]postoperatively( P<0.05). Pain scores and complication rates were zero in both groups after 6 months. Conclusions:ADM repair improves early recovery but may increase transient sensory complications. Both methods are safe for clinical application.
9.Efficacy of the transpubic access in the treatment of female urogenital tract injury
Weidong ZHU ; Jiemin SI ; Chongrui JIN ; Wenxiong SONG ; Xuxiao YE ; Lujie SONG ; Qiang FU ; Yinglong SA
Chinese Journal of Urology 2025;46(10):774-777
Objective:To explore the application value of transpubic access on female urogenital tract injury.Methods:A retrospective analysis was conducted on 15 female patients with urogenital tract injury caused by trauma admitted to our department from May 2020 to October 2024,all of whom were complicated urethral stricture or atresia,accompanied by urethrovaginal fistula or vaginorectal fistula. All patients underwent suprapubic vesicostomy before surgery,and 1 case underwent sigmoidostomy simultaneously. The mean age of the patients was(29.6 ± 3.2)years old,and the course of disease was 6-24 months. Preoperative urethrography and urethroscope showed the location of urethral stenosis,with proximal urethra stricture in 7 cases and distal urethra stricture in 8 cases. The average length of strictures was(2.8±0.2)cm. The urethral ultrasonography,magnetic resonance and CTU examination showed 8 patients were complicated with urethrovaginal fistula,and 1 patient was complicated with vaginorectal fistula. All patients underwent transpubic access and resection of symphysis pubis. According to the specific conditions of urethral stricture,7 of them underwent end-to-end urethral anastomosis,5 cases underwent bladder wall flap urethroplasty,3 cases underwent vulva flap urethroplasty,8 cases underwent urethral vaginal fistula repair,1 case underwent vagino-rectal fistula repair,and 7 cases underwent vaginoplasty during the operation.Results:All the 15 patients underwent successful operation without complication. After the catheter being removed 4 weeks after surgery,2 patients had urgent urinary incontinence and 3 patients had stress urinary incontinence. The bladder neck was reconstructed 3 months after surgery,the symptoms of urinary incontinence improved in 1 case,urinary incontinence remained in 2 cases,and pharmaceutical or physical therapy were continued. Two patients could not urinate normally after the catheter was removed and still carried the vesicostomy tube,waiting for further treatment. The other 8 patients had unobtrusive voiding after extubating,and were followed up for an average of(22.5±3.2)months. There was no recurrence of urinary fistula,and the average maximum urinary flow rate was(22.8±3.2)ml/s.Conclusions:The transpubic approach is a safe and effective way to treat female genital tract injury by different surgical methods according to specific conditions,especially for patients with severe trauma,poor local tissue conditions,complicated urethrovaginal fistula or vagino-rectal fistula.
10.A systematic review of tools for assessing the readiness of patients with chronic diseases aged 10-19 to transition to adulthood
Sa WANG ; Huali MIAO ; Yuwei LI ; Hongwei WANG ; Caicai QIAO ; Weiting SONG
Chinese Journal of Nursing 2025;60(4):469-477
Objective To systematically evaluate the assessment tools of adolescent chronic disease patients'transition readiness to adults at home and abroad,and to provide references for medical personnel to choose appropriate tools.Methods CNKI,Wan Fang Data,CBM,PubMed,Web of Science,Embase and Cochrane were searched for literature related to the assessment tools of transition readiness in adolescents with chronic illnesses to adulthood from inception to August,2024.Literature screening and data extraction of the tools were extracted independently by 2 researchers.At the same time,the criteria for the selection of health measurement tools based on consensus(COSMIN)systematic evaluation guidelines were used to evaluate the inclusion assessment tools,and recommendations were finally formed.Results A total of 29 articles were included,involving 9 universal and 5 specific assessment tools of adolescent chronic illnesses transition readiness.The Transition Readiness Assessment Questionnaire has satisfactory content validity and internal consistency,and it is recommended as Grade A.The Grade C included the Am I ON TRAC for adult care?Questionnaire and the State Assessment Questionnaire for Transition,Epilepsy-specific Transition Readiness Assessment Questionnaire and the Readiness for Adult Care in Rheumatology,while the others are recommended as Grade B.Conclusion There are a variety of tools to assess the transition readiness of adolescents with chronic diseases to adults,and there are few tools suitable for adolescents with chronic diseases in China,with few specific tools.After comprehensive consideration,the Transition Readiness Assessment Questionnaire can be recommended temporarily.

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