Objective:To establish silicone cartilage models of donor-sites for the microtia patients by using digital technology, and to explore the application of surgical simulation in auricular reconstruction.Methods:From June 2018 to October 2019, 19 congenital microtia patients underwent thoracic CT scans and following three-dimensional costal cartilage imaging with Mimics software at the Nanfang Hospital, Southern Medical University. Among these patients, 16 were males and 3 were females. The mean age of patients was 16 years (range 8 to 35 years). Silicon cartilage models were produced by 3D printing and used for surgical planning and preoperative simulation in ear framework fabrication. Cartilaginous framework was sculptured according to the simulation during operation. Patients were followed up for a minimum of six months to evaluate the size, outline, height and auriculocephalic angle of the reconstructed ear. The satisfactory outcomes of the patients were scored according to a 5-point Likert scale.Results:All the patients received the surgical simulation and sculpture training with silicone cartilage models before operation. Auricular reconstruction was completed successfully according to the simulation. The duration of sculpture was shortened to 1-1.5 hours. There were no serious complications, such as hematoma, inflammation, skin necrosis and framework exposure. The contour of reconstructed ear was natural and clear over a 6 months follow-up, and all the patients were satisfied with their surgical outcomes.Conclusions:With the application of digital technology and silicone cartilage models by 3D printing to the surgical planning and training in microtia patients, patient-specific framework is fabricated with precisely assembling, which not only shortens the operation time, but also provides the unexperienced surgeons with a safe and effective training of ear framework fabrication.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.

The hair cycle is effected by various components in the microenvironment of hair follicle niche. The dermal adipocytes, as an important part, has been shown to be relevant to epidermal homoeostasis during hair follicle regeneration, and the periodic change of hair also affects the dermal adipocytes. This article reviewed the relationship between dermal adipocytes and hair follicle, and tried to find a new sight in the field of hair regenerations.