Objective To analyze the current situation of accidental injuries among the population in Garze Tibetan are-a,clarify the main causes and risk factors,and develop prevention and control strategies based on crisis management and system management theory to reduce the incidence and disability rate.Methods Collect data from 78 166 outpatient patients from 2018 to 2024 and 15 015 hospitalized patients from 2021 to 2024,and analyze the distribution characteristics and causes of injuries.Results The incidence rate of Han ethnicity is higher than that of Tibetan ethnicity,higher in males than females,and higher in adults than minors;The incidence rate of elderly Han people aged 60 and above is expected to reach nearly 9％in 2024,while the working age population of Tibetan people is expected to sharply increase in 2021.The incidence rate in southern and eastern counties is significantly higher than in other regions,and higher in rural areas than in urban areas.Falls account for 49.64％of the total,followed by labor injuries,falls from heights,and traffic accidents.There are differences in the causes and locations of injuries among different age groups.Conclusion Accidental injuries are closely related to ethnicity,age,gender,and regional distribution.Falls,falls,labor injuries,and car accidents are the four main causes.It is recommended to construct a full cycle emergency response mechanism based on crisis management theory,and integrate multidimensional resources such as medical,transportation,and community through system management theory to strengthen the construction of orthopedic sub specialties and targeted prevention and treatment.

Objective To analyze the current situation of accidental injuries among the population in Garze Tibetan are-a,clarify the main causes and risk factors,and develop prevention and control strategies based on crisis management and system management theory to reduce the incidence and disability rate.Methods Collect data from 78 166 outpatient patients from 2018 to 2024 and 15 015 hospitalized patients from 2021 to 2024,and analyze the distribution characteristics and causes of injuries.Results The incidence rate of Han ethnicity is higher than that of Tibetan ethnicity,higher in males than females,and higher in adults than minors;The incidence rate of elderly Han people aged 60 and above is expected to reach nearly 9％in 2024,while the working age population of Tibetan people is expected to sharply increase in 2021.The incidence rate in southern and eastern counties is significantly higher than in other regions,and higher in rural areas than in urban areas.Falls account for 49.64％of the total,followed by labor injuries,falls from heights,and traffic accidents.There are differences in the causes and locations of injuries among different age groups.Conclusion Accidental injuries are closely related to ethnicity,age,gender,and regional distribution.Falls,falls,labor injuries,and car accidents are the four main causes.It is recommended to construct a full cycle emergency response mechanism based on crisis management theory,and integrate multidimensional resources such as medical,transportation,and community through system management theory to strengthen the construction of orthopedic sub specialties and targeted prevention and treatment.

Objedctive To study the mechanism of GnRH agalogus(Alarelin)on[ Ca2 + ]; mobilization in stomach smooth muscle cells (SSMc)of rats. Methods Cells were cutured and loaded with Fluo-3-AM. [Ca2 + ]; was measured by nuomeent intensity(FL) in each cell with confocal micoopy. Results (1 ) In Hanks solution. l0-7, l0-6, l0 - 5mol L- 1 Alarelin can elevate[ Ca2 + ], its peak - resting values reached 6. 00 ?0. 50 .9. 23 ?0. 62. l8. 97 ?2. 42 respectively, which indicate that the level of [Ca2+ ]; act in an deede- pendent and time - dependent. (2) thntredly. when Alarelin was 10 4mol?Ｌ－１, its peak - resting value only reached 6. 32 ?0 .67, conpared with Alarelin l0 5m.l L－1 which was sigificantly lower(P 0. 05 ). (5 )When pertreatment with Lacidipine in Hanks solution, the effect of Alarelin l0 5mol L-1.as partly inhibited(P