Objective:To compare and analyze the clinical diagnostic values of five thyroid nodule malignant risk stratification guidelines.Methods:From October 2019 to October 2021, 926 cases of patients with 1 027 thyroid nodules were recruited in the Second Affiliated Hospital of Xi ′an Jiaotong University. All nodules were categorized individually according to 2015 American Thyroid Association for Ultrasound Malignancy Risk Stratification of Thyroid Nodules in Adults Guidelines(ATA guidelines), 2016 the Korean Society of Radiology and the Korean Society of Thyroid Radiology Thyroid Imaging Reporting and Data Systems(K-TIRADS), 2017 European Thyroid Association Thyroid Imaging Reporting and Data Systems(Eu-TIRADS), 2017 American College of Radiology Thyroid Imaging Reporting and Data Systems (ACR TI-RADS), and 2020 Chinese Thyroid Imaging Reporting and Data System (C-TIRADS). The pathological results were taken as the gold standard, the malignancy ratio of nodules of different categories in each system was calculated. ROC curves were plotted to evaluate the diagnostic efficiencies of different systems, and DeLong test was used to compare the areas under ROC curves. The sensitivity and specificity of different systems were calculated when the maximum point of the Youden index was the optimal cut-off value.Results:In the same stratified system, there were statistically significant differences in the malignant proportion of nodules of different grades ( P<0.05). The malignant proportion of nodules in the high-risk group showed no significant difference among different stratified systems ( P>0.05). Except for C-TIRADS, the malignant proportion of nodules was increased with the increase of diagnostic grade at each grade of the other four stratification systems. ROC curve showed that AUCs of ATA guidelines, K-TIRADS, EU-TIRADS, ACR TI-RADS and C-TIRADS were 0.814, 0.819, 0.814, 0.820 and 0.802, respectively, there was no statistical significance in AUC of different stratification systems (all P>0.05). The optimal truncation values in differentiating benign and malignant nodules were middle-risk malignant nodules, moderately suspicious malignant nodules, middle-risk malignant nodules, class 4 and class 4B. The diagnostic of five stratification systems showed that ATA guidelines had the highest sensitivity (0.784), C-TIRADS had the highest specificity (0.854). Conclusions:The five stratified systems have similar efficacy in differentiating benign and malignant thyroid nodules, and all of them have good diagnostic value.

Objective:To observe the effect of hyperbaric oxygen(HBO) in the treatment of sudden deafness for the patients with type 2 diabetes.Methods:A total of 80 patients with sudden deafness due to type 2 diabetes treated at the No.904 Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army from January 2010 to December 2019 were selected and divided into observation group (40 cases) and control group (40 cases) according to the random number table method. The control group received glucocorticoids, volume expansion, vascular dilation, and nerve nutrition therapies. The observation group was given HBO therapy on the basis of the treatment of the control group. The efficacy, hearing, blood glucose, inflammation factor, stress indicators, adverse reactions, and complications of the two groups after 3 courses of treatment were observed.Results:After 3 courses of treatment, the total effective rate of the observation group (80.0%) was higher than that of the control group (57.5%), and the difference was statistically significant ( P<0.05). After treatment, the pure tone hearing thresholds of both groups were lower than that before the treatment; the pure tone hearing threshold of the observation group was lower than that of the control group( P<0.05). After treatment, the hearing threshold gain of the observation group was significantly larger than that of the control group ( P<0.05). After 3 courses of treatment, within each group, C-reactive protein was obviously lower than before, while the levels of nitric oxide (NO) and nitric oxide synthesis rate-limiting enzyme (NOS) were all significantly higher than before ( P<0.05). After treatment, C-reactive protein of the observation group was remarkably lower than that of the control group, and the levels of NO and NOS in the observation group were significantly higher than those in the control group ( P<0.05). After each course of treatment, the levels of blood glucose in the observation group was lower than that in the control group ( P<0.05). In the observation group, the level of blood glucose after the third course of treatment was obviously lower than that after the first course of treatment, and the difference was statistically significant ( P<0.05). There was no significant difference in the incidence of adverse reaction, complications, total adverse reaction, and total complication between the two groups ( P>0.05). Conclusion:HBO as an auxiliary treatment for the sudden deafness patients due to type 2 diabetes can reduce the inflammatory response and stress response, reduce blood glucose level, improve the clinical efficacy and has high safety, which is worth of clinical application.

Objective:To observe the effect of hyperbaric oxygen(HBO) in the treatment of sudden deafness for the patients with type 2 diabetes.Methods:A total of 80 patients with sudden deafness due to type 2 diabetes treated at the No.904 Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army from January 2010 to December 2019 were selected and divided into observation group (40 cases) and control group (40 cases) according to the random number table method. The control group received glucocorticoids, volume expansion, vascular dilation, and nerve nutrition therapies. The observation group was given HBO therapy on the basis of the treatment of the control group. The efficacy, hearing, blood glucose, inflammation factor, stress indicators, adverse reactions, and complications of the two groups after 3 courses of treatment were observed.Results:After 3 courses of treatment, the total effective rate of the observation group (80.0%) was higher than that of the control group (57.5%), and the difference was statistically significant ( P<0.05). After treatment, the pure tone hearing thresholds of both groups were lower than that before the treatment; the pure tone hearing threshold of the observation group was lower than that of the control group( P<0.05). After treatment, the hearing threshold gain of the observation group was significantly larger than that of the control group ( P<0.05). After 3 courses of treatment, within each group, C-reactive protein was obviously lower than before, while the levels of nitric oxide (NO) and nitric oxide synthesis rate-limiting enzyme (NOS) were all significantly higher than before ( P<0.05). After treatment, C-reactive protein of the observation group was remarkably lower than that of the control group, and the levels of NO and NOS in the observation group were significantly higher than those in the control group ( P<0.05). After each course of treatment, the levels of blood glucose in the observation group was lower than that in the control group ( P<0.05). In the observation group, the level of blood glucose after the third course of treatment was obviously lower than that after the first course of treatment, and the difference was statistically significant ( P<0.05). There was no significant difference in the incidence of adverse reaction, complications, total adverse reaction, and total complication between the two groups ( P>0.05). Conclusion:HBO as an auxiliary treatment for the sudden deafness patients due to type 2 diabetes can reduce the inflammatory response and stress response, reduce blood glucose level, improve the clinical efficacy and has high safety, which is worth of clinical application.

Objective: To evaluate the application effect of the platform switching implants in maxillary anterior region, to explore the effect of platform switching technology on the surrounding tissues. Methods: 55 patients with 60 single maxillary anterior implants were divided into two groups: platform-switching implants group (Ankylos), 25 patients with 28 implants; butt-joint implants group (Nobel Replace), 30 patients with 32 implants. The patients received follow-up care more than 1 and 2 year after the final setting of the prosthesis, at which time periapical radiographs were taken. The marginal bone level around the implant and Pink Esthetic Score (PES) were measured for comparison. Results : The average marginal bone changes of platform-switching implants after 1 year and 2 year were (-0.41 ± 0.36) mm and (-0.55 ± 0.33) mm respectively; and the ones of butt-joint implants were (-1.77 ± 0.54) mm and (-1.82 ± 0.61) mm. The average PES of platform- switched implants after 1 year and 2 year were 10.43 ± 1.37 and 10.32 ± 1.21 respectively; the ones of butt-joint implants were 9.21 ± 0.97 and 9.16 ± 0.95. There were significantly differences of marginal bone changes and PES between both groups (P < 0.05). Conclusion Platform switching implant in the maxillary aesthetics area is more effective in preserving the surrounding bone tissue and aesthetic effect.

It had some advantages when microwave induced hyperthermia were used to treat inferior femora and superior shinbone tumor.The device of circulation water,which could induce hypothermia during the treatment procedure needed to be used.Large amount of normal saline at the room temperature was perfused through this device,so the temperature of surrounding normal tissues and organs was reducd and the functions of nerve,vessel and knee were protected.It is safe and convenient measure that keep the operation go on smoothly.Summarized 54 cases of superior shinbone tumor that were used this device in the operation and experienced that it provided an effectiveness support for the operation.

It had some advantages when microwave induced hyperthermia were used to treat inferior femora and superior shinbone tumor.The device of circulation water,which could induce hypothermia during the treatment procedure needed to be used.Large amount of normal saline at the room temperature was perfused through this device,so the temperature of surrounding normal tissues and organs was reducd and the functions of nerve,vessel and knee were protected.It is safe and convenient measure that keep the operation go on smoothly.Summarized 54 cases of superior shinbone tumor that were used this device in the operation and experienced that it provided an effectiveness support for the operation.