1.Impact of mitochondrial quality control imbalance on post-traumatic organ dysfunction: a review
Anjing LU ; Yuanlan LU ; Jing LIU ; Ruilie WANG ; Guang YANG ; Jin WU ; Shuhong WANG ; Changqiang LIANG
Chinese Journal of Trauma 2025;41(2):212-218
Trauma can disrupt the body′s internal environment, resulting in organ dysfunction. This may manifest as symptoms such as acute respiratory distress, liver and kidney dysfunction, circulatory disorders and neurological damage. Mitochondrial quality control (MQC), encompassing processes like autophagy, dynamic changes, and biogenesis, plays an essential role in maintaining mitochondrial function. Stress responses following trauma can cause mitochondrial dysfunction and MQC imbalance, thereby exacerbating organ injury. Correcting MQC imbalance can improve organ function. Current researches on MQC in post-traumatic organ dysfunction mainly focuses on imbalance in specific MQC mechanism, lacking a systemic understanding of its incidence and progression. To this end, the authors reviewed the progress in researches on the impact of MQC imbalance on post-traumatic organ dysfunction, aiming to provide insights for clinical treatment.
2.Impact of mitochondrial quality control imbalance on post-traumatic organ dysfunction: a review
Anjing LU ; Yuanlan LU ; Jing LIU ; Ruilie WANG ; Guang YANG ; Jin WU ; Shuhong WANG ; Changqiang LIANG
Chinese Journal of Trauma 2025;41(2):212-218
Trauma can disrupt the body′s internal environment, resulting in organ dysfunction. This may manifest as symptoms such as acute respiratory distress, liver and kidney dysfunction, circulatory disorders and neurological damage. Mitochondrial quality control (MQC), encompassing processes like autophagy, dynamic changes, and biogenesis, plays an essential role in maintaining mitochondrial function. Stress responses following trauma can cause mitochondrial dysfunction and MQC imbalance, thereby exacerbating organ injury. Correcting MQC imbalance can improve organ function. Current researches on MQC in post-traumatic organ dysfunction mainly focuses on imbalance in specific MQC mechanism, lacking a systemic understanding of its incidence and progression. To this end, the authors reviewed the progress in researches on the impact of MQC imbalance on post-traumatic organ dysfunction, aiming to provide insights for clinical treatment.
3.Study on 4 cases of mushroom poisoning with amanita and identification of poison
Jie HU ; Haijiao LI ; Qingfeng MENG ; Fuping LAI ; Ruilie WANG ; Yuanlan LU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2023;41(8):622-625
Different kinds of poisonous mushrooms contain different toxic components. Acute liver injury caused by amanita mushroom is the main cause of death from poisonous mushroom poisoning in China. Consumption of poisonous mushrooms has an incubation period, there is a false recovery period in the clinical process, and the early performance is slight and does not attract enough attention from doctors, and it is easy to miss the treatment opportunity. The clinical characteristics, treatment and identification of mushrooms containing amanita in 4 patients were analyzed in order to improve clinicians' understanding of the diagnosis and treatment of mushroom poisoning and early species identification.
4.Study on 4 cases of mushroom poisoning with amanita and identification of poison
Jie HU ; Haijiao LI ; Qingfeng MENG ; Fuping LAI ; Ruilie WANG ; Yuanlan LU
Chinese Journal of Industrial Hygiene and Occupational Diseases 2023;41(8):622-625
Different kinds of poisonous mushrooms contain different toxic components. Acute liver injury caused by amanita mushroom is the main cause of death from poisonous mushroom poisoning in China. Consumption of poisonous mushrooms has an incubation period, there is a false recovery period in the clinical process, and the early performance is slight and does not attract enough attention from doctors, and it is easy to miss the treatment opportunity. The clinical characteristics, treatment and identification of mushrooms containing amanita in 4 patients were analyzed in order to improve clinicians' understanding of the diagnosis and treatment of mushroom poisoning and early species identification.

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