As the significance of the doctor-patient relationship has become increasingly prominent,seeking effective communication methods to enhance the quality of interaction between the two sides has become an urgent need.This paper aimed to explore the application of multimodal communication and its role in promoting the doctor-patient relationship,as well as to analyze and improve the comprehensiveness and effectiveness of doctor-patient communication by integrating various communication modes such as language,non-verbal behavior,visual aids,and digital tools.Through interviews and investigations conducted at three tertiary A hospitals in M city,it was found that multimodal communication can significantly enhance the clarity of information transmission and patients'understanding,promote emotional expression,and encourage patients to actively participate in the treatment process,thereby effectively improving the harmony of doctor-patient interaction.Multimodal communication also played a crucial role in strengthening the doctor-patient relationship,mainly in terms of being conducive to building a mutually trusting doctor-patient relationship,facilitating various communication strategies for empathy,enhancing multi-channel information exchange approaches,mediating crises and conflicts in the doctor-patient relationship,and other aspects.Therefore,this paper proposed strategies for enhancing a harmonious doctor-patient relationship through multimodal communication.These strategies included building multimodal bridges for differential adaptation and improving the practical mechanism of doctor-patient communication strategies;training doctors'multimodal communication skills and enhancing the effective transmission of emotion and information;implementing a multimodal evaluation and feedback mechanism and establishing an immediate and long-term evaluation system;and motivating patients to participate in multimodal strategies to enhance their initiative in medical interactions.Future medical practice and policymaking should attach greater importance to the systematic training and implementation of multimodal communication strategies to fully realize their potential value in the doctor-patient relationship.

As the significance of the doctor-patient relationship has become increasingly prominent,seeking effective communication methods to enhance the quality of interaction between the two sides has become an urgent need.This paper aimed to explore the application of multimodal communication and its role in promoting the doctor-patient relationship,as well as to analyze and improve the comprehensiveness and effectiveness of doctor-patient communication by integrating various communication modes such as language,non-verbal behavior,visual aids,and digital tools.Through interviews and investigations conducted at three tertiary A hospitals in M city,it was found that multimodal communication can significantly enhance the clarity of information transmission and patients'understanding,promote emotional expression,and encourage patients to actively participate in the treatment process,thereby effectively improving the harmony of doctor-patient interaction.Multimodal communication also played a crucial role in strengthening the doctor-patient relationship,mainly in terms of being conducive to building a mutually trusting doctor-patient relationship,facilitating various communication strategies for empathy,enhancing multi-channel information exchange approaches,mediating crises and conflicts in the doctor-patient relationship,and other aspects.Therefore,this paper proposed strategies for enhancing a harmonious doctor-patient relationship through multimodal communication.These strategies included building multimodal bridges for differential adaptation and improving the practical mechanism of doctor-patient communication strategies;training doctors'multimodal communication skills and enhancing the effective transmission of emotion and information;implementing a multimodal evaluation and feedback mechanism and establishing an immediate and long-term evaluation system;and motivating patients to participate in multimodal strategies to enhance their initiative in medical interactions.Future medical practice and policymaking should attach greater importance to the systematic training and implementation of multimodal communication strategies to fully realize their potential value in the doctor-patient relationship.

Objective:To explore the effect of hip arthroscopy on improving the cross-sectional kinematics of the lower limbs in patients with femoral acetabular impingement (FAI).Methods:Eight FAI patients who underwent hip arthroscopy in the Department of Sports Medicine of Peking University Third Hospital from October 2021 to February 2022 were prospectively included, including 3 males and 5 females, with an age of 35.3±13.0 years (range 17-53 years), height of 168.0±12.8 cm (range 154-192 cm), weight of 61.1±8.5 kg (range 52-74 kg) and body mass index of 21.7±2.6 kg/m 2 (range 17.6-24.5 kg/m 2). There were 3 left hips and 5 right hips. FADIR (flexion, adduction and internal rotation test) was positive in all patients and FABER (flexion, abduction and external rotation test) was positive in 4 patients. Modified Harris hip score (mHHS) and visual analogue scale (VAS) of the affected hip joint were compared before the surgery and at the follow-up of 10 months. By using a markerless motion capture system, foot progression angles during normal gait, double-leg squat, forward lunge, single-leg standing and stepping in place were measured and compared before the surgery and at the follow-up of 10 months postoperative results. Results:All the 8 patients underwent the surgery successfully and were followed up for 11.0±1.2 months. The mHHS scores before the surgery and at the follow-up of 10 months were 60.9±20.5 vs. 82.9±7.3 with significant difference ( t=-3.07, P=0.018). The iHOT-12 scores before the surgery and at the follow-up of 10 months for the affected hips were 51.4±23.7 vs. 79.2±14.6 with significant difference ( t=-3.76, P=0.007). The VAS scores before the surgery and at the follow-up of 10 months were 4.6±2.3 vs. 1.5±0.9 with significant difference ( t=3.16, P=0.016). There was no significant difference in foot progression angle between the healthy side and the affected side for all movement trials before the surgery and at the follow-up of 10 months ( P>0.05). During normal gait, the postoperative and preoperative foot progression angles for the healthy side and the affected side were 26.52°±5.97 vs. 34.4°±7.20° and 24.41°±3.70° vs. 30.80°±6.43°with significant reduction ( t=2.83, P=0.013; t=3.05, P=0.041). While there was no significant difference in foot progression angles for double-leg squat, forward lunge, single-leg standing and stepping in place before the surgery and at the follow-up of 10 months ( P>0.05). Conclusion:Hip arthroscopy can change the cross-sectional kinematic characteristics of the lower limbs, potentially improving the progression angle in FAI patients.

Humans ; Arthroscopy ; Injections, Intra-Articular ; Hip Joint/surgery* ; Pain ; Ultrasonography, Interventional ; Treatment Outcome

Interferons (IFNs) are natural proteins produced by wide variety of cells in response to viral infection or other biological inducers, and they execute diversified functions as antiviral defense, immune activation and cell growth regulation. Four genes encoding porcine interferons (PoIFN), PoIFN-alpha, PoIFN-gamma, PoIFN-alphagamma or PolFN-omega, were cloned and sequenced. The four types of porcine interferon genes were subcloned into the pET-His vector, and expressed in Escherichia coli Rosetta (DE3). The recombinant products were purified and renaturalized from inclusion bodies to obtain a native state of well biological activity. Antiviral activity assays for porcine interferons were performed and evaluated by standard procedures in following cell/virus test systems: Marc-145/PRRSV, Marc-145/VSV, PK-15/VSV, Vero/VSV or MDBK/VSV. The data showed that both PoIFN-alpha and PoIFN-alpagamma demonstrated significant antiviral activities, and the titer of them against PRRSV was up to 10(8) U/mg. PoIFN-gamma had approximately half or one-thirds antiviral activity of PoIFN-alpha. PoIFN-omega showed inconspicuous antiviral activity.
Amino Acid Sequence ; Animals ; Antiviral Agents ; pharmacology ; Cloning, Molecular ; Escherichia coli ; genetics ; metabolism ; Interferon Type I ; biosynthesis ; genetics ; pharmacology ; Interferon-gamma ; biosynthesis ; genetics ; pharmacology ; Molecular Sequence Data ; Porcine respiratory and reproductive syndrome virus ; drug effects ; Recombinant Proteins ; biosynthesis ; genetics ; pharmacology ; Swine