1.External ocular manifestations among patients diagnosed with Coronavirus disease 2019 in a referral center in the Philippines.
Alyssa Louise B. Pejana-Paulino ; Aramis B. Torrefranca Jr. ; Nilo Vincent DG. Florcruz ; Ma. Dominga B. Padilla
Acta Medica Philippina 2026;60(1):69-77
BACKGROUND AND OBJECTIVES
The global pandemic caused by Coronavirus Disease 2019 (COVID-19) has affected millions, with growing evidence of the potential role of ocular tissues in viral transmission. At the time of writing, local data regarding the phenomenon was limited. This study investigated external ocular manifestations in patients with COVID-19 at a referral center in the Philippines, examined correlations between demographics, systemic manifestations, and laboratory results with ocular manifestations, and determined their timing relative to systemic symptoms.
METHODSThis single-center, descriptive cross-sectional study was carried out from December 8 to 18, 2020 at the adult COVID-19 wards of the Philippine General Hospital involving 72 participants. Data collection involved relevant clinical history taking and performing gross eye examination. The prevalence of ocular manifestations was described with 95% confidence intervals. Correlations between ocular manifestations and quantitative variables were analyzed with point-biserial correlation, and associations with qualitative variables were tested using chi-square or Fisher’s exact tests.
RESULTSAmong participants, 31.9% presented with ocular manifestations with foreign body sensation as the most prevalent ocular symptom (11.1%) and conjunctival hyperemia as the most prevalent ocular finding (19.4%). The median age of patients with ocular manifestations was 41 years old with a higher prevalence in the male population (73.9%, CI=95%, p=0.001). No significant correlation was observed between presence of external ocular manifestations and the different systemic and ocular co-morbidities as well as with COVID-19 clinical classification. Among those who experienced symptoms, majority (29.2%) of the patients experienced systemic symptoms prior to the onset of ocular symptoms. Ocular complaints may present as the sole manifestation (13.9%). Several laboratory parameters were measured and only temperature and AST levels showed a low positive correlation with the presence of ocular manifestations.
CONCLUSIONOcular manifestations occur in roughly one third of patients with COVID-19 based on this study population. With some individuals presenting with ocular signs or symptoms as the initial and sole manifestation, healthcare practitioners must exercise caution and remain vigilant in managing patients who present as such. At the time of writing, this is the first local study investigating the different external ocular manifestations in patients with COVID-19. There is a need to pursue more robust studies and conduct more local investigations which will guide both ophthalmologists and other practitioners in strengthening existing guidelines regarding precautionary practices, clinical diagnosis, and management of COVID-19 patients.
Human ; Sars-cov-2 ; Covid-19 ; Philippines ; Adult ; Association ; Classification ; Collection ; Confidence Intervals ; Coronavirus ; Cross-sectional Studies ; Data Collection ; Demography ; Diagnosis ; Disease ; Exercise ; Eye ; Foreign Bodies ; History ; Hospitals ; Hospitals, General ; Hyperemia ; Laboratories ; Male ; Morbidity ; Ophthalmologists ; Pandemics ; Patients ; Population ; Prevalence ; Referral And Consultation ; Role ; Sensation ; Temperature ; Time ; Tissues ; Volition ; World Health Organization ; Writing
2.ACTA at the crossroads.
Acta Medica Philippina 2026;60(1):5-6
Academic publishing is at a critical juncture. The challenges faced by the academics are mired in controversy. Among theseare three hotly debated concerns. First is the issue of whether technological innovations such as artificial intelligence (AI)improves research efficiency or if its use sacrifices research integrity.Another is the controversy between paywall publishingand open access. Lastly, adapting an appropriate business model for sustainability is a contentious issue and the choice betweena commercial or a university-based publishing platform is a difficult one.
Traditional models of scientific investigation relied on tedious intellectual calisthenics in all aspects of research —identifying research gaps, reviewing of published literature, devising valid methodology, collecting data, analysing results, and,finally, drawing conclusions. With the advent of powerful tools employing artificial intelligence, these heavy tasks are efficientlycarried out. The dilemma lies in determining which parts of the work can be attributed to the authors and which are ascribedto the output of large language models (LLMs) and other automated assistance employed.Despite requiring adequate vettingby experts of these AI-aided output, many in the scientific community still question these methods. Can research employingAI be considered honest work? Will full disclosure answer doubts as to the integrity of the scientific work?
Indeed, LLMs just gather information that is already out there, albeit more efficiently. After all, science progresses bystanding on the shoulder of giants. AI makes such work comprehensive and efficient. Standing on those proverbial shoulders,however, require access to prior work, hence our next challenge in academic publishing--open access versus paid access.Paywalls limit the benefits of valuable research to institutions and universities with the capacity to pay. Excluded from these arethose from low resourced countries, with nations from the global south being affected disproportionately. Additionally, whilenumerous authors appreciate the features of open access as it improves their impact and visibility, many feel unduly burdenedsince the cost of publishing in this format is passed on to them.
This brings us to our third issue: who bears the cost of academic publishing? Indeed, it is a lucrative industry, generatingan annual revenue of US$19 billion and an estimated 40 percent profit margin. Many, however, find fault in this businessmodel as concerns about the profit motives of the commercial publishers far overshadow their sustainability goals.
How do we navigate this landscape of controversies? We, at the ACTA, as part of the community of scholars, would needto clarify our mission. Our goals for this publication should be consistent with our values. These values, such as scientific rigor,integrity, and accountability, should be reflected in our policies. We should be cognizant of the role we play in national scientificdiscourse while we endeavor to make an impact in the global scene. We are accountable to our stakeholders — nurturingearly career scholars, supplying evidence to health policymakers, and being accountable to those who provide resources tosustain us. This stewardship is essential so that ACTA will stand shoulder to shoulder with the giants on which science buildsupon to benefit future generations.
Artificial Intelligence ; Commerce ; Costs And Cost Analysis ; Disclosure ; Drawing ; Efficiency ; Family Characteristics ; Forecasting ; Goals ; Gymnastics ; Health ; Health Resources ; Industry ; Intelligence ; Inventions ; Language ; Literature ; Methods ; Play And Playthings ; Policy ; Publications ; Publishing ; Research ; Residence Characteristics ; Role ; Science ; Shoulder ; Social Responsibility ; Universities ; Ursidae ; Volition ; Work ; World Health Organization
3.Perceived professional identity and role stress among midwifery students in South Central Mindanao: A cross-sectional study.
Elizabeth S. LIBA ; Charlie C. FALGUERA ; Mandy Roie A. ATENDIDO
Acta Medica Philippina 2026;60(8):69-76
BACKGROUND
Professional identity plays a significant role in alleviating role stress among healthcare professionals. However, these two factors are poorly explored in the midwifery profession.
OBJECTIVETo determine the perceived level of professional identity and role stress and the relationship between them among midwifery students.
METHODSA cross-sectional study design was employed involving 379 midwifery students from SOCCSKSARGEN Region, Mindanao. Participants were selected through purposive sampling. Macleod Clark Professional Identity Scale (MCPIS-9) and twelve-item Role Stress Scale (RSS) were used in gathering the data. Spearman rho, point-biserial correlation, and F-test were used for data analysis.
RESULTSThe students’ mean score in professional identity was high (4.07, SD=0.46) while the mean score of the overall role stress was low (2.47, SD=0.51). There was a positive and significant relationship between age (rs=0.207, P=CONCLUSION
Midwifery students’ perceived level of professional identity was high, while their level of role stress was quite low. Age, year level, and marital status were significantly correlated with their levels of professional identity and role stress. Moreover, students with a higher level of professional identity may report low levels of role ambiguity, role overload, role conflict, and overall role stress.
Midwifery ; Students ; Role ; Cross-sectional Studies
4.Role of caffeine and ethanol in modulating expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG) during orthodontic tooth movement: An in vivo study.
Ardiansyah S. PAWINRU ; Eka ERWANSYAH ; Eddy Heriyanto HABAR ; Abul FAUZI ; AMINULLAH ; Gita GAYATRI ; Yustisia PUSPITASARI ; Ita Purnama ALWI ; Andi Husnul HASANAH
Acta Medica Philippina 2026;60(8):115-122
BACKGROUND AND OBJECTIVES
Orthodontic tooth movement is driven by bone remodeling influenced by systemic factors, including caffeine and ethanol. This study aimed to investigate the effects of caffeine and ethanol on the expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG), key bone remodeling biomarkers, during orthodontic tooth movement.
METHODSA laboratory experimental study was conducted on 30 male Wistar rats divided into three groups: K1 (orthodontic force only), K2 (force + caffeine), and K3 (force + ethanol). Orthodontic force was applied using Ni-Ti coil springs. Caffeine and ethanol were administered orally daily. On days 7 and 14, maxillary tissues were collected and analyzed via immunohistochemistry for RANK and OPG expression. Data were analyzed using One-Way ANOVA and Independent Sample T-tests with significance at pRESULTS
Caffeine and ethanol administration increased RANK and OPG expression compared to controls; however, only the ethanol group showed a significant increase in RANK expression on day 14 (p = 0.044). OPG expression was significantly higher in treatment groups at both time points (pCONCLUSION
Caffeine and ethanol modulate bone remodeling marker expression during orthodontic force application, with ethanol significantly increasing RANK expression at later stages. Further studies are needed to clarify the clinical implications for orthodontic treatment.
Animals ; Tooth Movement Techniques ; Tooth Movement ; Osteoprotegerin ; Role ; Movement ; Ethanol ; Bone Remodeling ; Caffeine ; Immunohistochemistry
5.Analysis of forensic and drowning death studies using VOSviewer: A bibliometric study.
Iwan AFLANIE ; Adelia Umi HABIBAH ; Naila Amirah RAHMADINA ; Pandji Winata NURIKHWAN
Acta Medica Philippina 2026;60(9):68-79
BACKGROUND
Drowning is a significant cause of accidental death worldwide, and forensic investigation plays an important role in determining the circumstances and causes of these deaths. Despite its importance, research in forensic investigations related to drowning remains fragmented and insufficiently characterized.
OBJECTIVEThis study aimed to examine trends and patterns in publications on forensic examinations related to drowning deaths. Specifically, it sought to identify research gaps, highlight key contributions, and determine major thematic areas in the field.
METHODSA total of 116 articles published between 2014 and 2023 were retrieved from the PubMed database using search terms related to forensic science and drowning deaths. Bibliometric analysis was performed using VOSviewer (version 1.6.20) to identify research clusters, patterns of author collaboration, and keyword co-occurrence. Filtered data were exported in .txt format to facilitate analysis and visualization.
RESULTSVisualization analysis identified seven thematic clusters. China had the highest number of publications on this topic. The Academy of Forensic Science in Shanghai was the most productive institution, while Fa Yi Xue Za Zhi had the highest number of publications. Lippmann J. was the most prolific author. The most frequently cited source received 180 citations. The three most commonly discussed topics were drowning, forensic pathology, and autopsy, while the most frequent terms overall were forensic pathology, autopsy, and people.
CONCLUSIONThe findings indicate substantial initial research interest in forensic investigations of drowning. However, publication output during the study period showed a downward trend, with a decrease of 16.4%. This decline suggests a notable gap in the literature and highlights the need for further research in this field.
Research ; Pathology ; Publications ; Science ; Role ; Forensic Pathology ; Forensic Sciences
6.Perceived professional identity and role stress among midwifery students in South Central Mindanao: A cross-sectional study.
Elizabeth S. LIBA ; Charlie C. FALGUERA ; Mandy Roie A. ATENDIDO
Acta Medica Philippina 2026;60(8):69-76
BACKGROUND
Professional identity plays a significant role in alleviating role stress among healthcare professionals. However, these two factors are poorly explored in the midwifery profession.
OBJECTIVETo determine the perceived level of professional identity and role stress and the relationship between them among midwifery students.
METHODSA cross-sectional study design was employed involving 379 midwifery students from SOCCSKSARGEN Region, Mindanao. Participants were selected through purposive sampling. Macleod Clark Professional Identity Scale (MCPIS-9) and twelve-item Role Stress Scale (RSS) were used in gathering the data. Spearman rho, point-biserial correlation, and F-test were used for data analysis.
RESULTSThe students’ mean score in professional identity was high (4.07, SD=0.46) while the mean score of the overall role stress was low (2.47, SD=0.51). There was a positive and significant relationship between age (rs=0.207, P=CONCLUSION
Midwifery students’ perceived level of professional identity was high, while their level of role stress was quite low. Age, year level, and marital status were significantly correlated with their levels of professional identity and role stress. Moreover, students with a higher level of professional identity may report low levels of role ambiguity, role overload, role conflict, and overall role stress.
Midwifery ; Students ; Role ; Cross-sectional Studies
7.Role of caffeine and ethanol in modulating expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG) during orthodontic tooth movement: An in vivo study.
Ardiansyah S. PAWINRU ; Eka ERWANSYAH ; Eddy Heriyanto HABAR ; Abul FAUZI ; AMINULLAH ; Gita GAYATRI ; Yustisia PUSPITASARI ; Ita Purnama ALWI ; Andi Husnul HASANAH
Acta Medica Philippina 2026;60(8):115-122
BACKGROUND AND OBJECTIVES
Orthodontic tooth movement is driven by bone remodeling influenced by systemic factors, including caffeine and ethanol. This study aimed to investigate the effects of caffeine and ethanol on the expression of Receptor Activator of Nuclear Factor κβ (RANK) and Osteoprotegerin (OPG), key bone remodeling biomarkers, during orthodontic tooth movement.
METHODSA laboratory experimental study was conducted on 30 male Wistar rats divided into three groups: K1 (orthodontic force only), K2 (force + caffeine), and K3 (force + ethanol). Orthodontic force was applied using Ni-Ti coil springs. Caffeine and ethanol were administered orally daily. On days 7 and 14, maxillary tissues were collected and analyzed via immunohistochemistry for RANK and OPG expression. Data were analyzed using One-Way ANOVA and Independent Sample T-tests with significance at pRESULTS
Caffeine and ethanol administration increased RANK and OPG expression compared to controls; however, only the ethanol group showed a significant increase in RANK expression on day 14 (p = 0.044). OPG expression was significantly higher in treatment groups at both time points (pCONCLUSION
Caffeine and ethanol modulate bone remodeling marker expression during orthodontic force application, with ethanol significantly increasing RANK expression at later stages. Further studies are needed to clarify the clinical implications for orthodontic treatment.
Animals ; Tooth Movement Techniques ; Tooth Movement ; Osteoprotegerin ; Role ; Movement ; Ethanol ; Bone Remodeling ; Caffeine ; Immunohistochemistry
8.Beyond the bedside: Understanding nurses' transition into academic roles
Judith Odanee Magwilang ; Steven Pasayan ; Christian Gaerlan ; Alfredo Fomocao jr.
Philippine Journal of Nursing 2025;95(1):6-16
INTRODUCTION
While research has explored various aspects of nursing practice, there is a limited understanding of the specific challenges and experiences of nurses' transitioning into the academia. This knowledge gap hinders the development of effective support strategies to facilitate career transition. This study aimed to explore the lived experiences of nurses who transitioned from bedside to academic roles.
METHODSThis study employed an interpretive phenomenological approach guided by the Consolidated Criteria for Reporting Qualitative Research (COREQ). The participants of this study were 21 faculty members from the two Colleges of Nursing (University of Cordilleras and Mountain Province State University). Purposive sampling was used in the selection of participants. Data was collected between April and June 2024. NVIVO 15 was used to organize, analyze, and visualize the data.
RESULTSFive primary themes emerged, highlighting the complexities of transitioning from bedside to academia. These said themes included: Navigating the Transition, encompassing the integration of clinical identity with the faculty role and adapting to new responsibilities; Impact of Clinical Experience on teaching; Reconciling Professional Identities, involving adaptation to the academic environment and balancing clinical knowledge with academic expectations; Challenges and Support Systems encountered during the transition; and Motivations in Shaping Future Nurses, reflecting the desire to mentor and guide. These themes underscored the significant adjustments that nurses have to undergo and the interplay between their clinical background and academic responsibilities.
CONCLUSIONThe findings of this study highlighted the struggles experienced by nurses as they shift from clinical roles to work in academic institutions. To enable this transition, such support measures should be designed to deal with specific problems not captured within more general support measures. Furthermore, the integration of the clinical and academic roles was equally important for not only quality nursing education but also for safe and quality patient care. Making use of the clinical perspective in positional environments can improve nursing education. Mentorship programmes may also be used to foster the transition and development of future nurses. Lastly, studies have shown the importance of developing policies and programs capable of encouraging this particular change in career and, more broadly, ensuring a healthy nursing education workforce.
Human ; Role
9.Continuing role of traditional birth attendants and home delivery determinants in Palawan, Philippines: A mixed-methods study.
Philippine Journal of Nursing 2025;95(2):71-82
BACKGROUND
Despite policies promoting facility births, home deliveries attended by traditional birth attendants (TBAs/hilot) persist in rural Philippines. We examined determinants of home delivery and the continuing role of TBAs in Palawan.
METHODSWe used a convergent mixed-methods design: a survey of 48 postpartum mothers and 48 in-depth interviews (45–90 minutes). The survey captured socio-demographics, delivery histories, and preferences; interviews explored decision-making, experiences with TBAs and facilities, and barriers to care. Descriptive statistics summarized quantitative patterns; inductive thematic analysis generated qualitative themes. Findings were integrated via a joint-display matrix to produce meta-inferences.
RESULTSRespondents reported 141 lifetime deliveries; 85.8% (121/141) occurred at home and 81.0% (98/121) of home births were TBA-attended. Three-quarters lived >1 km from the nearest facility, and 89.6% had monthly household income below the provincial poverty threshold. Over half (54.2%) planned their most recent birth at home and 81.3% intended to deliver at home again. Qualitatively, mothers valued TBAs' accessibility, flexible/low payment, and relational care. Facilities were associated with indirect costs, distance, scolding, invasive procedures, and loss of dignity; decisions were commonly joint with partners/elders, reflecting relational autonomy.
CONCLUSIONHome birth in Palawan represents a constrained preference shaped by structural barriers (poverty, distance), cultural trust in TBAs, and relational decision-making. Safety messaging alone is insufficient without respectful, affordable, and accessible facility care. Policy actions should: (1) reduce non-fee costs (transport/food; maternity waiting homes), (2) institutionalize Respectful Maternity Care, and (3) integrate TBAs as trained community referral partners within UHC.
Human ; Methods ; Parturition ; Role ; Philippines
10.Identifying the roles of occupational therapists among the LGBT community: An analysis of a panel discussion
Rod Charlie Delos Reyes ; Mark Andrè ; Blanco ; Roland Sardan
Philippine Journal of Allied Health Sciences 2024;7(2):63-69
Occupational therapists are known to be holistic practitioners who facilitate occupational performance and promote occupational justice. However,
limited literature explores the role of the profession for members of the society who identify themselves as lesbians, gays, bisexuals, and transgender
(LGBT). This paper analyzes a panel discussion at an international event hosted by a university in the Philippines regarding gender and sexuality.
This short report aims to identify the roles of occupational therapists among the LGBT community through the lens of professionals. Upon thematic
analysis of the transcription of the discussion, five roles of occupational therapists were identified. These are (1) navigators on the complexity of
gender and sexuality, (2) researchers on evidenced-based and practical practices toward the LGBT community, (3) enablers of gender expression
among the LGBT community, (4) allies of the LGBT community, and (5) advocates of inclusion in all spaces. It provides actionable approaches for
occupational therapists to facilitate gender-affirming healthcare for the LGBT community. Moreover, these findings hold the potential to influence
forthcoming policies and educational initiatives for both occupational therapists and allied professionals.
Role
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Occupational Therapy


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