1.A case of penetrating craniomaxillofacial injury in the time of COVID-19
Oliver Gabriel M. Baccay ; Jesusa M. Santos-Perez ; Jay Pee M. Amable
Philippine Journal of Otolaryngology Head and Neck Surgery 2025;40(Supplement):17-20
OBJECTIVE
To describe a case of a craniomaxillofacial penetrating injury focusing on the importance of a multidisciplinary approach with insights into the surgical planning for successful removal of the foreign body during the pandemic.
METHODSDesign: Case Report
Setting: Tertiary Government Training Hospital
Patient: One
RESULTSA 15-year-old boy presented with a work-related puncture wound in the right nasomaxillary area with accompanying soft-tissue swelling. Physical examination of his face showed no external foreign body. Craniofacial computed tomography scans revealed a rod-shaped opaque foreign body about 12 cm in length and 9 mm in diameter lodged in the right maxillary sinus extending to the right temporal lobe. The otolaryngology-head and neck surgeon and neurosurgeon planned the crucial extraction of the foreign body, but the requirement for a negative RT-PCR, blood products, and additional imaging delayed this emergent operation. The foreign body was eventually removed via combined trans-antral approach and right frontotemporal craniotomy, zygotomy, and craniectomy around the foreign body in the temporal floor with duraplasty and cranioplasty.
CONCLUSIONSuccessful treatment of penetrating craniomaxillofacial injuries involves diligent clinical assessment, radiologic diagnosis and a well-planned multidisciplinary surgical approach. Delays in treatment may be beneficial if they allow precise location of the foreign body and thorough evaluation of involved structures. Safeguarding the healthcare workers during the pandemic was as important as ensuring a successful and safe surgery for the patient.
Human ; Male ; Adolescent: 13-18 Yrs Old ; Foreign Bodies ; Temporal Lobe ; Maxillary Sinus ; Middle Cerebral Artery ; Infratemporal Fossa
2.A multimodal intervention program to improve sexual health and self-perceived quality of life in patients treated for cervical cancer:a randomized prospective study (PROVIDENCE trial)
Blanca GIL-IBAÑEZ ; Núria CARRERAS-DIEGUEZ ; Gregorio LÓPEZ ; Beatriz SÁNCHEZ-HOYO ; Beatrice Conti NUÑO ; Reyes OLIVER-PEREZ ; Camil CASTELO-BRANCO ; Tiermes MARINA ; Aureli TORNÉ ; Alvaro TEJERIZO ; Berta DIAZ-FEIJOO
Journal of Gynecologic Oncology 2025;36(4):e56-
Background:
Patients with cervical cancer treatment experience an impairment of sexual function and quality of life. This issue is usually underreported and undertreated, and evidence-based interventions are lacking. Prevention of sexual dysfunction is a crucial pillar in improving the quality of life of these patients. The primary objective of this trial is to evaluate the impact of a multimodal intervention, encompassing prevention of vaginal dysfunction and patient education, on sexual function and quality of life in cervical cancer survivors utilizing patient-reported outcome measurements.
Methods
Multi-institutional, randomized clinical trial where patients will be randomized 1:2 at diagnosis of initial or locally advanced cervical cancer to control arm or intervention arm. After treatment, control arm patients will undergo standard follow-up by their referring physician. The multimodal intervention for patients in the intervention group includes application of vaginal estrogens plus hyaluronic-acid cream along with use of vaginal vibrator, systematic evaluation of the need of systemic hormone replacement therapy and treatment if needed, and access to online content about sexuality, nutrition, sports and lifestyle habits.Through 4 appointments (at diagnosis, 1, 6, and 12 months after treatment), sexual health, vaginal trophism and self-perceived quality of life of patients in both arms will be assessed with validated questionnaires as female sexual function index (FSFI), European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30, and Cx-24, Cervantes Scale, vaginal health index and vaginal thickness assessed by ultrasound. The major inclusion criteria will be patients aged ≥18 years with the International Federation of Gynecology and Obstetrics stage I–III cervical cancer treated with surgery and/or radiotherapy. The primary endpoint will be FSFI score 12 months after treatment, which will be compared between groups. Uni- and multivariate analysis will be performed to identify factors influencing sexual function recovery after treatment. The sample size will be of 120 eligible patients, who will be randomized to detect an improvement of 5.2 points in FSFI score. Complete accrual is estimated in March 2026. To date, the present study has no external funding.


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