THE INFLUENCE OF DENTAL BLEACHING TECHNIQUES ON MICROLEAKAGE OF COMPOSITE RESIN RESTORATION: A SYSTEMATIC REVIEW Dental bleaching is a popular and conservative aesthetic technique used to whiten discolored teeth. However, there are concerns about the adverse effects of bleaching on composite restorations, such as color change, decreased bond strength, and microleakage. This review aims to evaluate the influence of tooth bleaching on composite restoration microleakage and to investigate the suggested methods used to prevent microleakage in composite restorations. A comprehensive search was conducted using four databases - PubMed, Scopus, Web of Science, and EBSCOhost - using a list of core keywords that included: ((Bleaching OR Whitening) AND ("dental adhesives" OR bonding OR "total-etch" OR "Self-etch" OR "total etch" OR "Self etch”) AND (Dental OR Enamel OR Dentin)). The inclusion criteria were in-vitro experiments written in English that involved composite restoration microleakage as the primary outcome due to bleaching. Of 1524 articles from the initial search, 18 were eligible for this review. Among the two major groups included in the study, the post-restorative bleaching group demonstrates highly varied results on the occurrence of microleakage. Conversely, the pre-restorative bleaching group indicates that bleaching materials can adversely affect the marginal integrity of the composite restoration. It was suggested that the resulting microleakage can cause problems such as recurrent caries and postoperative hypersensitivity and may be due to the natural bleaching mechanism depending on the oxidation reaction to remove the stains on the tooth surface. This releases oxygen and free radicals, and the residual oxygen on the tooth surface may inhibit the resin polymerization and lead to microleakage but can be overcome by the help of antioxidant materials, such as sodium ascorbate. This review provides substantial evidence from the literature on the preventive mechanism of composite microleakage and precautionary techniques when bleaching on composite restorations.

OBJECTIVES: Breast cancer (BC) is the most common type of cancer worldwide. Globally, BC is rapidly becoming a major common health problem among women. This study aimed to evaluate the association between nutrient intake patterns and BC risk among Jordanian women.METHODS: A total of 400 Jordanian women 20-65 years of age were recruited in this case-control study. Two hundred women recently diagnosed with BC were matched in age, income, and marital status to 200 BC-free women. A food frequency questionnaire was used to assess nutrient intake patterns.RESULTS: In this study, 3 nutrient intake patterns were identified: a high vitamin C and β-carotene nutrient intake pattern; a high calcium, phosphorus, and vitamin D nutrient intake pattern; and a high-fat nutrient intake pattern. A significant increase in BC risk was associated with the high vitamin C and β-carotene nutrient pattern (the highest for the fourth quartile; odds ratio [OR], 5.42; 95% confidence interval [CI], 2.11 to 13.91; p(trend)=0.001). In the high calcium, phosphorus, and vitamin D nutrient pattern, a significant inverse trend was detected for the risk of BC. The high-fat nutrient pattern showed a significant direct association with BC risk in the third (OR, 3.88; 95% CI, 1.58 to 9.51) and fourth (OR, 3.87; 95% CI, 1.53 to 9.77) quartiles (p(trend)=0.001).CONCLUSIONS: A significant increase in BC risk was detected for the high vitamin C and β-carotene nutrient intake pattern and the high-fat nutrient intake pattern. However, for the high calcium, phosphorus, and vitamin D nutrient intake pattern, a significant inverse trend was observed.
Ascorbic Acid ; Breast Neoplasms ; Breast ; Calcium ; Case-Control Studies ; Diet ; Female ; Humans ; Jordan ; Marital Status ; Odds Ratio ; Phosphorus ; Vitamin D

OBJECTIVES: Breast cancer (BC) is the most common type of cancer worldwide. Globally, BC is rapidly becoming a major common health problem among women. This study aimed to evaluate the association between nutrient intake patterns and BC risk among Jordanian women. METHODS: A total of 400 Jordanian women 20-65 years of age were recruited in this case-control study. Two hundred women recently diagnosed with BC were matched in age, income, and marital status to 200 BC-free women. A food frequency questionnaire was used to assess nutrient intake patterns. RESULTS: In this study, 3 nutrient intake patterns were identified: a high vitamin C and β-carotene nutrient intake pattern; a high calcium, phosphorus, and vitamin D nutrient intake pattern; and a high-fat nutrient intake pattern. A significant increase in BC risk was associated with the high vitamin C and β-carotene nutrient pattern (the highest for the fourth quartile; odds ratio [OR], 5.42; 95% confidence interval [CI], 2.11 to 13.91; p(trend)=0.001). In the high calcium, phosphorus, and vitamin D nutrient pattern, a significant inverse trend was detected for the risk of BC. The high-fat nutrient pattern showed a significant direct association with BC risk in the third (OR, 3.88; 95% CI, 1.58 to 9.51) and fourth (OR, 3.87; 95% CI, 1.53 to 9.77) quartiles (p(trend)=0.001). CONCLUSIONS: A significant increase in BC risk was detected for the high vitamin C and β-carotene nutrient intake pattern and the high-fat nutrient intake pattern. However, for the high calcium, phosphorus, and vitamin D nutrient intake pattern, a significant inverse trend was observed.
Ascorbic Acid ; Breast Neoplasms ; Breast ; Calcium ; Case-Control Studies ; Diet ; Female ; Humans ; Jordan ; Marital Status ; Odds Ratio ; Phosphorus ; Vitamin D

OBJECTIVES: Breast cancer (BC) is the most common type of cancer worldwide. Globally, BC is rapidly becoming a major common health problem among women. This study aimed to evaluate the association between nutrient intake patterns and BC risk among Jordanian women. METHODS: A total of 400 Jordanian women 20-65 years of age were recruited in this case-control study. Two hundred women recently diagnosed with BC were matched in age, income, and marital status to 200 BC-free women. A food frequency questionnaire was used to assess nutrient intake patterns. RESULTS: In this study, 3 nutrient intake patterns were identified: a high vitamin C and β-carotene nutrient intake pattern; a high calcium, phosphorus, and vitamin D nutrient intake pattern; and a high-fat nutrient intake pattern. A significant increase in BC risk was associated with the high vitamin C and β-carotene nutrient pattern (the highest for the fourth quartile; odds ratio [OR], 5.42; 95% confidence interval [CI], 2.11 to 13.91; p(trend)=0.001). In the high calcium, phosphorus, and vitamin D nutrient pattern, a significant inverse trend was detected for the risk of BC. The high-fat nutrient pattern showed a significant direct association with BC risk in the third (OR, 3.88; 95% CI, 1.58 to 9.51) and fourth (OR, 3.87; 95% CI, 1.53 to 9.77) quartiles (p(trend)=0.001). CONCLUSIONS A significant increase in BC risk was detected for the high vitamin C and β-carotene nutrient intake pattern and the high-fat nutrient intake pattern. However, for the high calcium, phosphorus, and vitamin D nutrient intake pattern, a significant inverse trend was observed.