Objective This study was to explore factors related to early radial artery occlusion(RAO)associated transradial approach(TRA).Methods Patients who underwent the TRA from July 2021 to Jan 2024 were included in our study.Patients were divided into radial artery occlusion group and non-radial artery occlusion group.The data of general demography,the number of radial artery punctures attempts,and whether add heparin to the Antispasmodic Agents were recorded to assess the incidence and predictors of RAO.Results A total of 543 patients were included in the study.All patients underwent ultrasound evaluation 24h after DSA.Among them,32 cases experienced RAO,while 511 cases did not experienced RAO.The occurrence rate of RAO was significantly higher in patients without addition of heparin to the antispasmodic agents for the prevention of radial artery spasm,those with more than 3 radial artery puncture attempts and those using either an 11 cm short sheath,or Cordis puncture needles(all P<0.05).Multiple logistic analysis showed that addition of heparin to the Antispasmodic Agents(OR=0.076,95% CI:0.018～0.321,P<0.001),less than 3 radial artery puncture attempts(OR=0.245,95% CI:0.111～0.541,P<0.001),using an 16 cm longer sheath(OR=0.195,95% CI:0.067～0.564,P=0.003),using an Terumo puncture needles(OR=0.325,95% CI:0.148～0.717,P=0.005)could reduce the incidence of RAO.Conclusions Anticoagulation with intrathecal heparin,application of trocar to improve the success rate of puncture,and the use of a 16 cm long sheath can significantly reduce the incidence of early RAO after DSA.

Objective To investigate the safety and feasibility of repeated recanalization of radial artery occlusion(RAO)in neurointerventional therapy.Methods The clinical data,including general information,surgery,ultrasonography,and surgery-related complications,of 18 patients with cerebrovascular diseases,who developed RAO after receiving transradial access(TRA)intervention at the Xiamen Branch of Affiliated Zhongshan Hospital of Fudan University of China between June 2022 and July 2023,were retrospectively analyzed.Results Of 18 patients,7 received two consecutive same-side TRA procedures and 11 received three consecutive same-side TRA procedures.RAO occurred in all patients after the initial cerebrovascular angiography,and subsequent neurointerventional treatment was successfully accomplished after RAO recanalization.The cerebrovascular diseases included arteriovenous malformations(n=3),arterial aneurysm(n=13),and arterial occlusion(n=2).A total of 29 times of puncturing at the site of RAO thrombus were carried out,including 23 times of successful recanalization(success rate being 79.3％).At(8.8±8.7)days after the first-time RAO recanalization,ultrasonography indicated that successful recanalization was obtained in 14 patients and persistent occlusion was seen in 4 patients.Thirteen patients were followed up for(7.8±2.7)months after the initial RAO recanalization,and the ultrasonography revealed that successful recanalization was obtained in 4 patients and persistent occlusion was seen in 9 patients.No severe complications occurred during the follow-up period.Conclusion In situ puncture of the RAO site after its recanalization to perform neurointerventional treatments is clinically safe and feasible.

Objective To investigate the safety and feasibility of performing neurointerventional diagnosis and treatment via left distal transradial access(dTRA)or via left transradial access(TRA).Methods The clinical data of patients,who received selective cerebral angiography or neurointerventional treatment using right/left dTRA/TRA at the Fudan Zhongshan Xiamen Branch Hospital of China between January 2022 and December 2023,were retrospectively analyzed.The clinical data including the basic information(including age,gender,diseases,etc.)and the clinical records(including operation mode,operative approach,X-ray fluoroscopy time,puncture-related complications,etc.)were collected.Results A total of 32 patients,who underwent neurointerventional treatment by using left dTRA/TRA approach(left-side group),were enrolled in this study.Among them 11 patients received selective cerebral angiography and 21 patients(having left-sided vertebrobasilar artery disease)received neurointerventional treatment.Other 49 patients,who underwent neurointerventional treatment by using right dTRA/TRA approach(right-side group)during the same period were also included in this study.Among them 19 patients received selective cerebral angiography and 30 patients(having right-sided vertebrobasilar artery disease)received neurointerventional treatment.Angiography reexamination was performed in the patients who had previously received treatment and all of them suffered from endovascular diseases of the anterior circulation system.All angiography and neurointerventional procedures were successfully accomplished with no occurrence of serious complications.In left-side group,4 patients changed to adopt TRA approach to complete the neurointerventional treatment,2 patients changed to adopt TFA approach to complete the neurointerventional treatment,and one patient changed to adopt TFA approach to complete the procedure due to vascular tortuosity of left dTRA.In patients receiving angiography,4 patients changed to adopt left TRA approach and 3 patients failed to complete the elective right subclavian artery catheterization.In patients receiving neurointerventional treatment,2 patients developed postoperative local bruising at the distal radial artery puncture point.Postoperative color ultrasound reexamination showed that there was no radial artery occlusion in all patients receiving angiography or neurointerventional treatment.In right-side group,among the patients receiving neurointerventional treatment,4 patients changed to adopt right TRA approach and 2 patients changed to adopt right TFA;among the patients receiving angiography,4 patients changed to adopt right TRA approach,and bilateral common carotid arteries and bilateral subclavian arteries catheterization were successfully accomplished in all patients;3 patients developed postoperative local bruising at the distal radial artery puncture point.Postoperative color ultrasound reexamination showed that there was no radial artery occlusion in all patients receiving angiography or neurointerventional treatment.No statistically significant differences in the success rate of distal radial artery puncture,intraoperative X-ray fluoroscopy time,catheterization success rate of 4 main vessels(including right common carotid artery,left common carotid artery,right subclavian artery and left subclavian artery),and incidence of postoperative puncture point complications existed between the two groups(all P＞0.05).Conclusion It is clinically safe and feasible to adopt left dTRA/TRA approach for performing selective cerebral angiography and neurointerventional treatment.