1.Hepatitis virus seroconversion among patients on maintenance hemodialysis in North India: a prospective cohort study
Pooja YADAV ; Arpita PANDA ; Shilpee KUMAR ; Rajesh KUMAR ; Deepthi NAIR
Osong Public Health and Research Perspectives 2026;17(2):182-187
Objectives:
Patients receiving hemodialysis (HD) are at increased risk of acquiring hepatitis B virus (HBV) and hepatitis C virus (HCV) due to repeated blood exposure, vascular access procedures, and blood transfusions. The study aimed to determine the seroconversion rates of HBV and HCV among patients undergoing dialysis and to identify associated risk factors.
Methods:
A total of 220 adult patients receiving dialysis who were seronegative for hepatitis B surface antigen (HBsAg) and anti-HCV antibodies at baseline were enrolled. Serologic testing was repeated at 6 months.
Results:
Sixteen patients (7.3%) seroconverted to HBsAg positivity, and 23 (10.5%) seroconvertedto anti-HCV positivity. HBV seroconversion was significantly associated with multiple dialysis center visits. HCV seroconversion was significantly associated with dialyzer reuse, multiple dialysis center visits, and dialysis duration ≥2 years. Elevated liver enzyme levels were stronglycorrelated with seroconversion for both viruses.
Conclusion
HBV and HCV seroconversion remain concerns in HD units. Standardized infection control practices, minimization of patient transfers, and strict adherence to nationalguidelines are essential to reducing risk.
2.Retraction: Difference of Neck Shortening in Femoral Neck Fracture between Femoral Neck System and Multiple Cannulated Cancellous Screws: Single Center, Prospective Randomized Controlled Trial
Saurabh GUPTA ; Abhay ELHENCE ; Sumit BANERJEE ; Sandeep YADAV ; Prabodh KANTIWAL ; Rajesh Kumar RAJNISH ; Pushpinder KHERA ; Rajesh MALHOTRA
Hip & Pelvis 2025;37(1):85-85
3.Comparing the Effect of Oil Massage on Phototherapy Efficacy in Term Neonates with Hyperbilirubinemia:A Randomized Controlled Trial
Dinesh KUMAR ; Durgesh KUMAR ; Pankaj Kumar ARYA ; Muniba ALIM ; Indra Kumar SHARMA ; Rajesh Kumar YADAV ; Nishant SHARMA
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):93-100
Purpose:
This study aimed to evaluate the efficacy of oil massage as an adjunct therapy for neonatal jaundice during phototherapy.
Methods:
A total of 160 neonates with unconjugated hyperbilirubinemia were enrolled and randomly allocated into two study groups using a computer-generated random number table.Group 1 (Intervention Group) consisted of 84 patients who received both phototherapy and massage therapy, while Group 2 (Control Group) consisted of 76 patients who received only phototherapy. The intervention group underwent massage therapy three times daily for 20 minutes over two consecutive days. Transcutaneous bilirubin levels were measured every eight hours. Additionally, the total duration of phototherapy and the 24-hour stool and urine output frequency were recorded in both groups.
Results:
There were no significant differences in the demographic characteristics between the two groups. However, stool frequency and urine output were significantly higher in the intervention group. The average duration of phototherapy was 19.4±4.17 hours in the intervention group compared to 28.4±6.58 hours in the control group (p<0.001). The rate of Transcutaneous bilirubin reduction was significantly higher in the intervention group during the first 24 hours. A rebound increase in bilirubin levels was observed at 40 and 48 hours in both groups after phototherapy was discontinued.
Conclusion
Phototherapy combined with massage significantly reduced total bilirubin levels in newborns with neonatal hyperbilirubinemia, making it a valuable adjunct treatment for the rapid reduction of bilirubin in neonates.
4.Comparing the Effect of Oil Massage on Phototherapy Efficacy in Term Neonates with Hyperbilirubinemia:A Randomized Controlled Trial
Dinesh KUMAR ; Durgesh KUMAR ; Pankaj Kumar ARYA ; Muniba ALIM ; Indra Kumar SHARMA ; Rajesh Kumar YADAV ; Nishant SHARMA
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):93-100
Purpose:
This study aimed to evaluate the efficacy of oil massage as an adjunct therapy for neonatal jaundice during phototherapy.
Methods:
A total of 160 neonates with unconjugated hyperbilirubinemia were enrolled and randomly allocated into two study groups using a computer-generated random number table.Group 1 (Intervention Group) consisted of 84 patients who received both phototherapy and massage therapy, while Group 2 (Control Group) consisted of 76 patients who received only phototherapy. The intervention group underwent massage therapy three times daily for 20 minutes over two consecutive days. Transcutaneous bilirubin levels were measured every eight hours. Additionally, the total duration of phototherapy and the 24-hour stool and urine output frequency were recorded in both groups.
Results:
There were no significant differences in the demographic characteristics between the two groups. However, stool frequency and urine output were significantly higher in the intervention group. The average duration of phototherapy was 19.4±4.17 hours in the intervention group compared to 28.4±6.58 hours in the control group (p<0.001). The rate of Transcutaneous bilirubin reduction was significantly higher in the intervention group during the first 24 hours. A rebound increase in bilirubin levels was observed at 40 and 48 hours in both groups after phototherapy was discontinued.
Conclusion
Phototherapy combined with massage significantly reduced total bilirubin levels in newborns with neonatal hyperbilirubinemia, making it a valuable adjunct treatment for the rapid reduction of bilirubin in neonates.
5.Retraction: Difference of Neck Shortening in Femoral Neck Fracture between Femoral Neck System and Multiple Cannulated Cancellous Screws: Single Center, Prospective Randomized Controlled Trial
Saurabh GUPTA ; Abhay ELHENCE ; Sumit BANERJEE ; Sandeep YADAV ; Prabodh KANTIWAL ; Rajesh Kumar RAJNISH ; Pushpinder KHERA ; Rajesh MALHOTRA
Hip & Pelvis 2025;37(1):85-85
6.Retraction: Difference of Neck Shortening in Femoral Neck Fracture between Femoral Neck System and Multiple Cannulated Cancellous Screws: Single Center, Prospective Randomized Controlled Trial
Saurabh GUPTA ; Abhay ELHENCE ; Sumit BANERJEE ; Sandeep YADAV ; Prabodh KANTIWAL ; Rajesh Kumar RAJNISH ; Pushpinder KHERA ; Rajesh MALHOTRA
Hip & Pelvis 2025;37(1):85-85
7.Comparing the Effect of Oil Massage on Phototherapy Efficacy in Term Neonates with Hyperbilirubinemia:A Randomized Controlled Trial
Dinesh KUMAR ; Durgesh KUMAR ; Pankaj Kumar ARYA ; Muniba ALIM ; Indra Kumar SHARMA ; Rajesh Kumar YADAV ; Nishant SHARMA
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):93-100
Purpose:
This study aimed to evaluate the efficacy of oil massage as an adjunct therapy for neonatal jaundice during phototherapy.
Methods:
A total of 160 neonates with unconjugated hyperbilirubinemia were enrolled and randomly allocated into two study groups using a computer-generated random number table.Group 1 (Intervention Group) consisted of 84 patients who received both phototherapy and massage therapy, while Group 2 (Control Group) consisted of 76 patients who received only phototherapy. The intervention group underwent massage therapy three times daily for 20 minutes over two consecutive days. Transcutaneous bilirubin levels were measured every eight hours. Additionally, the total duration of phototherapy and the 24-hour stool and urine output frequency were recorded in both groups.
Results:
There were no significant differences in the demographic characteristics between the two groups. However, stool frequency and urine output were significantly higher in the intervention group. The average duration of phototherapy was 19.4±4.17 hours in the intervention group compared to 28.4±6.58 hours in the control group (p<0.001). The rate of Transcutaneous bilirubin reduction was significantly higher in the intervention group during the first 24 hours. A rebound increase in bilirubin levels was observed at 40 and 48 hours in both groups after phototherapy was discontinued.
Conclusion
Phototherapy combined with massage significantly reduced total bilirubin levels in newborns with neonatal hyperbilirubinemia, making it a valuable adjunct treatment for the rapid reduction of bilirubin in neonates.
8.Comparing the Effect of Oil Massage on Phototherapy Efficacy in Term Neonates with Hyperbilirubinemia:A Randomized Controlled Trial
Dinesh KUMAR ; Durgesh KUMAR ; Pankaj Kumar ARYA ; Muniba ALIM ; Indra Kumar SHARMA ; Rajesh Kumar YADAV ; Nishant SHARMA
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):93-100
Purpose:
This study aimed to evaluate the efficacy of oil massage as an adjunct therapy for neonatal jaundice during phototherapy.
Methods:
A total of 160 neonates with unconjugated hyperbilirubinemia were enrolled and randomly allocated into two study groups using a computer-generated random number table.Group 1 (Intervention Group) consisted of 84 patients who received both phototherapy and massage therapy, while Group 2 (Control Group) consisted of 76 patients who received only phototherapy. The intervention group underwent massage therapy three times daily for 20 minutes over two consecutive days. Transcutaneous bilirubin levels were measured every eight hours. Additionally, the total duration of phototherapy and the 24-hour stool and urine output frequency were recorded in both groups.
Results:
There were no significant differences in the demographic characteristics between the two groups. However, stool frequency and urine output were significantly higher in the intervention group. The average duration of phototherapy was 19.4±4.17 hours in the intervention group compared to 28.4±6.58 hours in the control group (p<0.001). The rate of Transcutaneous bilirubin reduction was significantly higher in the intervention group during the first 24 hours. A rebound increase in bilirubin levels was observed at 40 and 48 hours in both groups after phototherapy was discontinued.
Conclusion
Phototherapy combined with massage significantly reduced total bilirubin levels in newborns with neonatal hyperbilirubinemia, making it a valuable adjunct treatment for the rapid reduction of bilirubin in neonates.
9.Comparing the Effect of Oil Massage on Phototherapy Efficacy in Term Neonates with Hyperbilirubinemia:A Randomized Controlled Trial
Dinesh KUMAR ; Durgesh KUMAR ; Pankaj Kumar ARYA ; Muniba ALIM ; Indra Kumar SHARMA ; Rajesh Kumar YADAV ; Nishant SHARMA
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):93-100
Purpose:
This study aimed to evaluate the efficacy of oil massage as an adjunct therapy for neonatal jaundice during phototherapy.
Methods:
A total of 160 neonates with unconjugated hyperbilirubinemia were enrolled and randomly allocated into two study groups using a computer-generated random number table.Group 1 (Intervention Group) consisted of 84 patients who received both phototherapy and massage therapy, while Group 2 (Control Group) consisted of 76 patients who received only phototherapy. The intervention group underwent massage therapy three times daily for 20 minutes over two consecutive days. Transcutaneous bilirubin levels were measured every eight hours. Additionally, the total duration of phototherapy and the 24-hour stool and urine output frequency were recorded in both groups.
Results:
There were no significant differences in the demographic characteristics between the two groups. However, stool frequency and urine output were significantly higher in the intervention group. The average duration of phototherapy was 19.4±4.17 hours in the intervention group compared to 28.4±6.58 hours in the control group (p<0.001). The rate of Transcutaneous bilirubin reduction was significantly higher in the intervention group during the first 24 hours. A rebound increase in bilirubin levels was observed at 40 and 48 hours in both groups after phototherapy was discontinued.
Conclusion
Phototherapy combined with massage significantly reduced total bilirubin levels in newborns with neonatal hyperbilirubinemia, making it a valuable adjunct treatment for the rapid reduction of bilirubin in neonates.
10.Effectiveness of pre-injection use of cryoanesthesia as compared to topical anesthetic gel in reducing pain perception during palatal injections: a randomized controlled trial
Siddhartha RAI ; Mehul Rajesh JAISANI ; Ashok DONGOL ; Pradeep ACHARYA ; Anjani Kumar YADAV
Journal of Dental Anesthesia and Pain Medicine 2024;24(2):91-99
Background:
Palatal injections are often painful. We aimed to compare topical ice and 20% benzocaine gel for pre-injection anesthesia before greater palatine nerve block (GPNB) injections.
Methods:
A randomized split-mouth clinical trial was conducted among patients aged 15-60-years needing bilateral GPNB injections. A total of 120 palatal sites from 60 patients were randomly allocated to Group A (topical ice) or Group B (20% benzocaine gel). Pain was evaluated using sound, eye, motor (SEM), and the visual analog scale (VAS) in both groups. Inferential analysis was performed using the Mann-Whitney U test.
Results:
The mean age of the participants was 20.5 ± 3.9 years. The median VAS score for group A was 11 (Q1 - Q3: 5.25 - 21.75), which was slightly higher than the 10 (Q1 - Q3: 4.0 – 26.75) reported in group B. However, the difference was not statistically significant (P = 0.955). The median SEM score for group A and group B was 3.5 (Q1 - Q3: 3.0 – 4.0) and 4.0 (Q1 - Q3: 3.0 - 4.0), respectively, which was statistically insignificant (P = 0.869).
Conclusion
Using ice as a form of topical anesthetic for achieving pre-injection anesthesia before GPNB was as effective as 20% benzocaine gel.

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