1.The Impact of Qur’anic Reading and Listening Duration and Frequency on Cognitive Performance and Hippocampal Function: A Systematic Review
Upik Rahmi ; Suci Tuty Putri ; Lisna Anisa Fitriana ; Farida Murtiani
The International Medical Journal Malaysia 2026;25(No. 1):7-15
Engaging with the Qur'an, whether through reading or listening, necessitates complex
cognitive processing of the written or spoken Arabic language. This activity demands
concentration and attention, thereby engaging cognitive functions such as selective
attention, Arabic language processing, and auditory perception. The purpose of this
paper is to review the effects of reading and listening to the Qur'an on hippocampal
cognitive function. A literature search was conducted using online databases:
ScienceDirect, PubMed/ Medline, and Scopus. The keywords used in the literature
search were “cognitive”, “Qur'an”, and “hippocampus”. This approach included six
full-length articles. A manual search of the cited references was also used to find
additional considerations for the discursive analysis of each topic discussed in this
review. As a sacred text, the Qur'an engages both reading and listening skills and
involves cognitive processes that impact memory and comprehension. Regular
engagement with the Qur'anic text and its recitation can significantly improve brain
activity, memory, and cognitive development. Reading and listening are essential skills
for language comprehension and communication. When a person reads the Qur'an, he
or she engages in visual Arabic language processing, while when listening to its
recitation, the person is involved in auditory language processing. These activities
stimulate different parts of the brain, contributing to a more comprehensive
understanding of the Qur'an text.
2.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
3.Utilizing Local Food Sources in a Sustainable Healthy Diet System and Psychosocial Care to Reduce Malnutrition
Lestari OCTAVIA ; Nia Novita WIRAWAN ; Intan Ria NIRMALA ; Verawati SUDARMA ; Patricia Budihartanti LIMAN ; Fitrianingsih ; Wahyu RAHARDJO ; Rahmi NURDIANI ; Wiralis
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):135-140
The magnitude of the problem of stunting is high in low- to middle-income countries, including Indonesia. The government of Indonesia has implemented specific and sensitive intervention programs to reduce this problem. This public health problem requires multidisciplinary management with suitable approaches and programs. In the first 1000 days of life, the quality of life is determined by conception and delivery until two years old.The requirement and fulfillment of nutrients during this period would benefit the growth and development of children. Indonesia is an archipelago country with 100,000 km of coastline and 16,771 islands with great potential for fishing. In coastal areas, optimizing protein consumption from the sea and enhancing educational programs in psychosocial care are appropriate intervention programs that will benefit stunting eradication. The complexity of the stunting problem puts authorities and other stakeholders together to formulate and design appropriate comprehensive intervention programs to improve the quality of life of the next generation.
4.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
5.Utilizing Local Food Sources in a Sustainable Healthy Diet System and Psychosocial Care to Reduce Malnutrition
Lestari OCTAVIA ; Nia Novita WIRAWAN ; Intan Ria NIRMALA ; Verawati SUDARMA ; Patricia Budihartanti LIMAN ; Fitrianingsih ; Wahyu RAHARDJO ; Rahmi NURDIANI ; Wiralis
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):135-140
The magnitude of the problem of stunting is high in low- to middle-income countries, including Indonesia. The government of Indonesia has implemented specific and sensitive intervention programs to reduce this problem. This public health problem requires multidisciplinary management with suitable approaches and programs. In the first 1000 days of life, the quality of life is determined by conception and delivery until two years old.The requirement and fulfillment of nutrients during this period would benefit the growth and development of children. Indonesia is an archipelago country with 100,000 km of coastline and 16,771 islands with great potential for fishing. In coastal areas, optimizing protein consumption from the sea and enhancing educational programs in psychosocial care are appropriate intervention programs that will benefit stunting eradication. The complexity of the stunting problem puts authorities and other stakeholders together to formulate and design appropriate comprehensive intervention programs to improve the quality of life of the next generation.
6.Utilizing Local Food Sources in a Sustainable Healthy Diet System and Psychosocial Care to Reduce Malnutrition
Lestari OCTAVIA ; Nia Novita WIRAWAN ; Intan Ria NIRMALA ; Verawati SUDARMA ; Patricia Budihartanti LIMAN ; Fitrianingsih ; Wahyu RAHARDJO ; Rahmi NURDIANI ; Wiralis
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):135-140
The magnitude of the problem of stunting is high in low- to middle-income countries, including Indonesia. The government of Indonesia has implemented specific and sensitive intervention programs to reduce this problem. This public health problem requires multidisciplinary management with suitable approaches and programs. In the first 1000 days of life, the quality of life is determined by conception and delivery until two years old.The requirement and fulfillment of nutrients during this period would benefit the growth and development of children. Indonesia is an archipelago country with 100,000 km of coastline and 16,771 islands with great potential for fishing. In coastal areas, optimizing protein consumption from the sea and enhancing educational programs in psychosocial care are appropriate intervention programs that will benefit stunting eradication. The complexity of the stunting problem puts authorities and other stakeholders together to formulate and design appropriate comprehensive intervention programs to improve the quality of life of the next generation.
7.Utilizing Local Food Sources in a Sustainable Healthy Diet System and Psychosocial Care to Reduce Malnutrition
Lestari OCTAVIA ; Nia Novita WIRAWAN ; Intan Ria NIRMALA ; Verawati SUDARMA ; Patricia Budihartanti LIMAN ; Fitrianingsih ; Wahyu RAHARDJO ; Rahmi NURDIANI ; Wiralis
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):135-140
The magnitude of the problem of stunting is high in low- to middle-income countries, including Indonesia. The government of Indonesia has implemented specific and sensitive intervention programs to reduce this problem. This public health problem requires multidisciplinary management with suitable approaches and programs. In the first 1000 days of life, the quality of life is determined by conception and delivery until two years old.The requirement and fulfillment of nutrients during this period would benefit the growth and development of children. Indonesia is an archipelago country with 100,000 km of coastline and 16,771 islands with great potential for fishing. In coastal areas, optimizing protein consumption from the sea and enhancing educational programs in psychosocial care are appropriate intervention programs that will benefit stunting eradication. The complexity of the stunting problem puts authorities and other stakeholders together to formulate and design appropriate comprehensive intervention programs to improve the quality of life of the next generation.
8.Co-occurrence of Frailty, Possible Sarcopenia, and Malnutrition in Community-Dwelling Older Outpatients: A Multicentre Observational Study
Siti SETIATI ; Kuntjoro HARIMURTI ; Ika FITRIANA ; Noto DWIMARTUTIE ; Rahmi ISTANTI ; Muhammad Khifzhon AZWAR ; I Gusti Putu Suka ARYANA ; Sri SUNARTI ; Agus SUDARSO ; Dina Aprillia ARIESTINE ; Lazuardhi DWIPA ; Novira WIDAJANTI ; Nur RIVIATI ; Roza MULYANA ; Rensa RENSA ; Yudo Murti MUPANGATI ; Fatichati BUDININGSIH ; Nina Kemala SARI
Annals of Geriatric Medicine and Research 2025;29(1):91-101
Background:
The co-occurrence of frailty, sarcopenia, and malnutrition was well studied in inpatient and nursing home settings, which was associated with higher risk of all-cause mortality. Multicentre data in community-dwelling outpatient setting were lacking. We aimed to find the prevalence of frailty, possible sarcopenia and malnutrition, their overlap and the associated factors in community-dwelling older outpatients.
Methods:
We collected data from community-dwelling outpatients aged ≥60 years in Indonesian geriatric care centres to conduct this cross-sectional study with bivariate and multivariable analyses. Frailty, possible sarcopenia, and malnutrition diagnoses were based on FRAIL scale, Asian Working Group for Sarcopenia 2019 consensus, and Mini Nutritional Assessment Short Form, respectively.
Results:
The prevalence of frailty, possible sarcopenia, and malnutrition in community-dwelling older outpatients were 13.6%, 45.5%, and 5.3%, respectively. The prevalence of co-occurrence of frailty, possible sarcopenia and malnutrition was 3.3%. It was associated with transient ischemic attack (TIA) and cerebrovascular accident (odds ratio [OR]=5.53, 95% confidence interval [CI] 1.48–20.61), cognitive impairment (OR=3.70, 95% CI 1.21–11.31), and dependent functional capacity (OR=11.62, 95% CI 3.38–39.99). Overlap of three evaluated syndromes was found in 24.1%, 7.2%, and 61.3% of subjects with frailty, possible sarcopenia, and malnutrition, respectively. It was characterized by a substantial proportion of female sex, older adults with low educational attainment, diabetes mellitus, hypertension, cognitive impairment, multimorbidity, and dependent functional status.
Conclusion
Approximately 1 in 30 community-dwelling older outpatients had overlapping frailty, possible sarcopenia, and malnutrition. The condition is associated with TIA and cerebrovascular accident, cognitive impairment, and dependent functional capacity. Standardized screening in community-dwelling older population is necessary.
9.Utilizing Local Food Sources in a Sustainable Healthy Diet System and Psychosocial Care to Reduce Malnutrition
Lestari OCTAVIA ; Nia Novita WIRAWAN ; Intan Ria NIRMALA ; Verawati SUDARMA ; Patricia Budihartanti LIMAN ; Fitrianingsih ; Wahyu RAHARDJO ; Rahmi NURDIANI ; Wiralis
Pediatric Gastroenterology, Hepatology & Nutrition 2025;28(2):135-140
The magnitude of the problem of stunting is high in low- to middle-income countries, including Indonesia. The government of Indonesia has implemented specific and sensitive intervention programs to reduce this problem. This public health problem requires multidisciplinary management with suitable approaches and programs. In the first 1000 days of life, the quality of life is determined by conception and delivery until two years old.The requirement and fulfillment of nutrients during this period would benefit the growth and development of children. Indonesia is an archipelago country with 100,000 km of coastline and 16,771 islands with great potential for fishing. In coastal areas, optimizing protein consumption from the sea and enhancing educational programs in psychosocial care are appropriate intervention programs that will benefit stunting eradication. The complexity of the stunting problem puts authorities and other stakeholders together to formulate and design appropriate comprehensive intervention programs to improve the quality of life of the next generation.
10.Development of mucosal vaccine delivery: an overview on the mucosal vaccines and their adjuvants
Rahmi ANGGRAENI ; Ika Dewi ANA ; Hevi WIHADMADYATAMI
Clinical and Experimental Vaccine Research 2022;11(3):235-248
Currently, mucosal infectious diseases are still a very high global health burden, but there are few effective vaccines to prevent mucosal-borne diseases. The development of mucosal vaccines requires the selection of appropriate antigens, delivery system strategies, and adjuvants to increase vaccine efficacy but limited studies have been conducted. The aim of this review is to describe the mucosal immune system, as well as the potential for the development of vaccines and mucosal adjuvants, and their challenges. The study was conducted by applying inclusion criteria for the articles, and a review was conducted by two readers with the agreement. It was known that mucosal vaccination is a potential route to be applied in future preventive efforts through vaccination. However, limited studies have been conducted so far and limited mucosal vaccination has been approved. New technological approaches such as material development involving nano- and micro-patterning are important to intensively open and investigate the potential area of development to provide better vaccination methods.


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