Objective To explore the effect of Jianpi Liqi(JPLQ)on the survival time of postoperative patients with colorectal cancer(CRC),and screen the independent factors affecting the prognosis of these patients.Methods A retrospective study was conduc-ted on 254 postoperative CRC patients who were admitted to the Department of General surgery,Longhua Hospital Affiliated to Shanghai University of TCM from July 2015 to December 2022.According to the use of ttraditional Chinese medicine(TCM)or JPLQ after the op-eration,they were divided into three groups:JPLQ group(n=51),non-JPLQ group(n=126)and western medicine group(n=77).The overall survival time was taken as the main observation index,then the survival curve was drawn by Kaplan-Meier,and the differ-ence of survival rate was compared by Log-rank test.The COX proportional hazard model was introduced to screen the statistically signifi-cant factors,univariate COX regression analysis preliminarily screened out the factors affecting the postoperative prognosis of CRC pa-tients,then stepwise regression was used for multivariate analysis to screen out the independent related factors that ultimately affect the prognosis of postoperative CRC patients.Results There was no significant difference among the survival curves of JPLQ group,non-JPLQ group and western medicine group.The results of univariate COX regression analysis showed that pathological stage Ⅲ-Ⅳ,number of positive lymph nodes,nerve/vascular invasion,mode of operation and biliary diseases were significant factors that may affect postopera-tive prognosis of CRC patients(P＜0.05).The results of multivariate COX regression analysis showed that more positive lymph nodes were the independent risk factor affecting the prognosis of CRC,while receiving laparoscopic surgery and having biliary diseases were inde-pendent protective factors affecting the prognosis of CRC(P＜0.05).Conclusion Compared with single western medical treatment,combination with western medicine and TCM especially represented as JPLQ has a tendency to prolong the survival time of CRC patients.More positive lymph nodes are the independent risk factors affecting the prognosis of CRC,while receiving laparoscopic surgery and having biliary diseases are independent protective factors.

Objective To explore the effect of Jianpi Liqi(JPLQ)on the survival time of postoperative patients with colorectal cancer(CRC),and screen the independent factors affecting the prognosis of these patients.Methods A retrospective study was conduc-ted on 254 postoperative CRC patients who were admitted to the Department of General surgery,Longhua Hospital Affiliated to Shanghai University of TCM from July 2015 to December 2022.According to the use of ttraditional Chinese medicine(TCM)or JPLQ after the op-eration,they were divided into three groups:JPLQ group(n=51),non-JPLQ group(n=126)and western medicine group(n=77).The overall survival time was taken as the main observation index,then the survival curve was drawn by Kaplan-Meier,and the differ-ence of survival rate was compared by Log-rank test.The COX proportional hazard model was introduced to screen the statistically signifi-cant factors,univariate COX regression analysis preliminarily screened out the factors affecting the postoperative prognosis of CRC pa-tients,then stepwise regression was used for multivariate analysis to screen out the independent related factors that ultimately affect the prognosis of postoperative CRC patients.Results There was no significant difference among the survival curves of JPLQ group,non-JPLQ group and western medicine group.The results of univariate COX regression analysis showed that pathological stage Ⅲ-Ⅳ,number of positive lymph nodes,nerve/vascular invasion,mode of operation and biliary diseases were significant factors that may affect postopera-tive prognosis of CRC patients(P＜0.05).The results of multivariate COX regression analysis showed that more positive lymph nodes were the independent risk factor affecting the prognosis of CRC,while receiving laparoscopic surgery and having biliary diseases were inde-pendent protective factors affecting the prognosis of CRC(P＜0.05).Conclusion Compared with single western medical treatment,combination with western medicine and TCM especially represented as JPLQ has a tendency to prolong the survival time of CRC patients.More positive lymph nodes are the independent risk factors affecting the prognosis of CRC,while receiving laparoscopic surgery and having biliary diseases are independent protective factors.

ObjectiveTo explore the chnical application value of ultrafine electronic endoscopy on the diagnosis of pediatric diseases of upper digestive tract.MethodsSeventy-five cases suspected upper gastrointestinal diseases from January 2009 to June 2010 were selected and were divided by systematic sampling method into observation group(47 cases) which was diagnosed with ultrafine electronic endoscopy and control group(28 cases) which was diagnosed by normal endoscopy.The data of diagnosis and compliance of two groups were observed and compared.ResultsCompliance rate of observation group and control group had significant difference[ 100.0％(47/47) vs.67.9％(19/28),P ＜ 0.01 ].The incidence rates of nausea,salivation and restless of observation group [ 8.5％(4/47 ),6.4％(3/47),8.5％(4/47 ) ]were lower than those of control group [39.3％(11/28),28.6％(8/28),50.0％(14/28)](P＜ 0.01 or ＜ 0.05).Correct diagnosis rate of control group was 84.2％ (16/19),while that of observation group was 95.7％ (45/47),but comparison of diagnosis showed no significant difference(P ＞ 0.05).The incidence rates of diaphragmatic spasm,sore throat and slow heartbeat in successful examination cases of control group[21.1％ (4/19),31.6％ (6/19),21.1％ (4/19) ]significant higher than those of observation group [0,2.1％ ( 1/47),2.1％(1/47) ](P ＜ 0.01 or ＜ 0.05 ).ConclusionUltrafine electronic endoscopy can achieve the same accuracy as normal endoscopy,but compared with normal endoscopy,it can improve the compliance of children during the examination and reduce the incidence of postoperative complications.

Objective To evaluate the effect of phosphocreatine in the treatment of infant with Pneumonia complicated with myocardial injury.Methods Sixty-eight infants with Pneumonia complicated with myocardial injury were randomized into treatment group (n = 36)and control group (n = 32) .The two groups were both treated with combined anti-infection, antiasthmatic and supporting treatments while the treatment group was given additional phosphocreatine.The ECG,recovery of myocardial enzymes, recovery time of major clinical symptoms and syndromes and the period of hospitalization of the two groups were compared.Results Recovery of ECG and myocardial enzymes in the treatment group (94.44％ and 94.44％)were significantly higher than those in the control group(78.13％ and 75.00％ ,respectively) (x2 =3.93 and 5.11 ,respectively,P ＜0.05).Recovery of clinical presentations were more rapid in the treatment group than that in control group (time for cough recovery, [9.5 ± 2.4]d vs.[11.1 ± 2.6]d ;time for rale disappearance, [8.1 ± 1.9]d vs.[10.3 ± 2.4]d) (t =2.63 and t =4.16 respectively ;P ＜0.05 and ＜0.01 respectively).The period of hospitalization was decreased markedly in the treatment group compared with that in the control group([11.5 ±2.2]d vs.[14.3 ±2.8]d) (t = 4.55, P ＜ 0.01) .ConclusionPhosphocreatine has prominent efficacy in the treatment of infantile Pneumonia complicated with myocardial injury.