Repetitive transcranial magnetic stimulation (rTMS) is a rapid and effective therapy for major depressive disorder; however, there is significant variability in therapeutic outcomes both within and across individuals, with approximately 50% of patients showing no response to rTMS treatment. Many studies have personalized the stimulation parameters of rTMS (e.g., location and intensity of stimulation) according to the anatomical and functional structure of the brain. In addition to these parameters, the internal states of the individual, such as circadian rhythm, behavior/cognition, neural oscillation, and neuroplasticity, also contribute to the variation in rTMS effects. In this review, we summarize the current literature on the interaction between rTMS and internal states. We propose two possible methods, multimodal treatment, and adaptive closed-loop treatment, to integrate patients' internal states to achieve better rTMS treatment for depression.
Humans ; Transcranial Magnetic Stimulation/methods* ; Depressive Disorder, Major/physiopathology* ; Neuronal Plasticity/physiology* ; Brain/physiopathology*

In recent years, ureteral repair and reconstruction techniques, such as appendiceal onlay flap, oral mucosal patch for repairing middle and upper ureteral stenosis, and Boari bladder muscle flap for repairing lower ureteral stenosis, have been continuously introduced and widely used to achieve satisfactory clinical results.In clinical practice, it is important to carefully select suitable patients and adequately prepare for the perioperative period. Factors to consider include the surgical approach, planning the sequence of left and right reconstruction, to ensure optimal results for ureteral repair. This paper provides a detailed account of our center’s experience, reviews relevant literature on robot-assisted appendix graft ureteroplasty combined with Boari flap ureteroplasty for one-stage repair of bilateral ureteral strictures, and discusses the current clinical progress.