1.The Role of Physical and Mental Exercise in the Association Between General Anesthesia and Mild Cognitive Impairment
Chenlu HU ; Lang XU ; Yiqing LI ; Zhaolan HUANG ; Qiuru ZHANG
Journal of Sun Yat-sen University(Medical Sciences) 2025;46(1):107-115
[Objective]To explore the correlation between general anesthesia and mild cognitive impairment in older adults so as to provide new ideas for early prevention and timely intervention of mild cognitive impairment(MCI).[Methods]Based on the baseline survey of the Hubei memory and aging cohort study(2018-2023),the participants completed a thorough neuropsychological assessment and physical examination,and self-reported a history of general anesthesia and surgery.The association of general anesthesia and MCI in the elderly was analyzed using the logistic regression model.In addition,the stratification and interaction analysis of anesthesia history,anesthesia number and physical intellectual exercise were conducted separately.[Results]A total of 5 069 older adults aged 65 and above were included in this study,including 3 692 city dwellers and 1 377 rural people,among whom were 2 584 women(51%).Out of the 1 472 participants with history of general anesthesia,249 people(17.4%)had MCI.After controlling for confounding factors,there was a 39.6%increased risk of MCI in older adults who underwent general anesthesia[OR=1.396,95%CI(1.169,1.668),P<0.001],suggesting that general anesthesia may be an independent influence on MCI.For the older adults who had one general anesthesia[OR=1.235,95%CI(1.001,1.523),P=0.049],two general anesthesia[OR=1.779,95%CI(1.292,2.450),P<0.001],and three OR more general anesthesia[OR=2.395,95%CI(1.589,3.610),P<0.001],their risks of MCI were increased by 23.5%,77.9%,and 139.5%,respectively.Compared with the older adults without a history of general anesthesia who did not exercise,the risk of developing MCI was significantly negatively correlated with the exercise group,cognitive exercise group,and combined exercise and cognitive exercise groups(all P<0.001).The risk of developing MCI in the exercise group was 60.2%of that in the no exercise group[OR=0.602,95%CI(0.456,0.795)],the risk in the cognitive exercise group was 42.4%of that in the no exercise group[OR=0.424,95%CI(0.294,0.613)],and the risk in the combined exercise and cognitive exercise group was 27.0%of that in the no exercise group[OR=0.270,95%CI(0.208,0.353)].In the older adults with a history of general anesthesia,compared with the no exercise group,the risk of developing MCI was significantly negatively correlated with the cognitive exercise group and the combined exercise and cognitive exercise group(all P<0.05).The risk of developing MCI in the cognitive exercise group was 47.7%of that in the no exercise group[OR=0.477,95%CI(0.256,0.892)],the risk in the combined exercise and cognitive exercise group was 34.5%of that in the no exercise group[OR=0.345,95%CI(0.220,0.540)],while the risk in the exercise-only group did not show a significant difference.[Conclusion]The risk of MCI increased significantly in older adults with a history of general anesthesia,and this risk increased with the times of anesthesia.Physical and mental exercise reduces the risk of MCI.it is recommended that older adults with a history of anesthesia incorporate physical and mental exercise into their daily lives to prevent mild cognitive impairment.
2.Problems and countermeasures for swift response to public complaints in health field from the perspective of mega-city governance
Lanting LYU ; Ruike YOU ; Qiuru HU ; Zhi WANG ; Yanan CHANG
Chinese Journal of Hospital Administration 2024;40(12):901-906
Swift response to public complaints is a mechanism reform and efficiency driven approach for grassroots social governance, which plays a pivotal role in urban management. This study took Beijing as an example to introduce the overall development process of swift response to public complaints and its development status in the medical and health service system. It was believed that the work of handling complaints is a reform and innovation to deepen grassroots governance in the capital and a vivid practice of implementing the patient-centered development concept in the medical and health service system. This study summarized the research progress related to swift response to public complaints. From the perspective of mega city governance, the existing problems in the work of handling complaints in health field were explored, including inconsistent implementation of policies, the need to improve supervision and evaluation mechanisms; The coexistence of obstacles to patient demands and ineffective complaints, and the impact on patient participation; Difficulties in cross institutional collaboration, and the need to improve the level of information construction. In response to these issues, it was proposed to further deepen institutional and mechanism reforms to ensure the effective implementation of policies; build a patient-centered healthcare service system that involves patient participation; promote cross institutional information sharing and improve the efficiency of handling appeals; standardize the classification and management of demands, promote the overall improvement of medical quality, so as to provide references for the continuous improvement of the work of handling complaints immediately and the enhancement of the medical and health service system in China′s mega cities.
3.Problems and countermeasures for swift response to public complaints in health field from the perspective of mega-city governance
Lanting LYU ; Ruike YOU ; Qiuru HU ; Zhi WANG ; Yanan CHANG
Chinese Journal of Hospital Administration 2024;40(12):901-906
Swift response to public complaints is a mechanism reform and efficiency driven approach for grassroots social governance, which plays a pivotal role in urban management. This study took Beijing as an example to introduce the overall development process of swift response to public complaints and its development status in the medical and health service system. It was believed that the work of handling complaints is a reform and innovation to deepen grassroots governance in the capital and a vivid practice of implementing the patient-centered development concept in the medical and health service system. This study summarized the research progress related to swift response to public complaints. From the perspective of mega city governance, the existing problems in the work of handling complaints in health field were explored, including inconsistent implementation of policies, the need to improve supervision and evaluation mechanisms; The coexistence of obstacles to patient demands and ineffective complaints, and the impact on patient participation; Difficulties in cross institutional collaboration, and the need to improve the level of information construction. In response to these issues, it was proposed to further deepen institutional and mechanism reforms to ensure the effective implementation of policies; build a patient-centered healthcare service system that involves patient participation; promote cross institutional information sharing and improve the efficiency of handling appeals; standardize the classification and management of demands, promote the overall improvement of medical quality, so as to provide references for the continuous improvement of the work of handling complaints immediately and the enhancement of the medical and health service system in China′s mega cities.
4.Status, problems and development advices on medical service price management
Lanting LYU ; Cangsong JIANG ; Qiuru HU ; Zhu LIN ; Lili WANG
Chinese Journal of Hospital Administration 2023;39(7):486-492
The reform of medical service prices in China has been launched, and the reasonable pricing and management of medical technology services are of great significance for improving patient well-being and advancing the reform of our medical system. The author provided a detailed review of the policy evolution, current management status, and main issues of medical service price management in China since 2000. The medical service price management policies in China since 2000 were divided into four evolutionary stages: initial exploration of decentralization, substantial development, continuous advancement, and deep promotion. The author also described the formation mechanism and pricing methods of international medical service prices, and compared the similarities and differences in medical service price management at home and abroad. Some suggestions were put forward for improving the macro reform of medical service price management in China.

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