The prevalence of inflammatory bowel disease(IBD),a recurrent,non-specific disease characterized by persistent inflammation of the gastrointestinal system,is rising globally.As high-throughput sequencing,culturomics,and metabolomics have advanced,so has our understanding of the role of gut flora and its metabolites contributed in the development of disease and overall health.This study examined the latest advances in research as well as the mechanism of action of common metabolites of intestinal flora in inflammatory bowel disease.

The prevalence of inflammatory bowel disease(IBD),a recurrent,non-specific disease characterized by persistent inflammation of the gastrointestinal system,is rising globally.As high-throughput sequencing,culturomics,and metabolomics have advanced,so has our understanding of the role of gut flora and its metabolites contributed in the development of disease and overall health.This study examined the latest advances in research as well as the mechanism of action of common metabolites of intestinal flora in inflammatory bowel disease.