OBJECTIVE: To analyze the current status and trends of the disease burden of knee osteoarthritis (KOA) in China from 1990 to 2023, and to examine the epidemiological characteristics of age, gender differences, and attribution to high body mass index (BMI), in order to provide a basis for formulating prevention and treatment strategies to reduce the disease burden of KOA in China. METHODS: Based on the 2023 Global Burden of Disease Study (GBD) database, data on the number, rate, and age-standardized rate of incidence, prevalence, disability-adjusted life years (DALYs) for KOA, and DALYs for KOA attributable to high BMI in the Chinese population from 1990 to 2023 were integrated. The Joinpoint 5.4.0.0 software was used to analyze the age and gender differences in KOA and the epidemiological characteristics attributable to high BMI. RESULTS: The standardized incidence, prevalence, and DALYs rates of KOA in China in 2023 increased by 6.46%, 6.43%, and 6.93%, respectively, compared with 1990. In terms of age, the disease burden of KOA in China was lowest in the age group of 30-34 years, with the highest incidence rate in the age group of 50-54 years, whereas the prevalence rate and DALYs rate continued to increase with age, and both were highest in the age group of ≥70 years. In terms of gender, all disease burden standardized rate indicators were higher in females than in males, and the difference widened with age. The rate of BMI-attributable DALYs increased at an annual average rate of 1.57% (95% CI: 1.55, 1.59) from 1990 to 2023, again with significant age and gender differences. CONCLUSION The continued growth of the KOA disease burden and significant population differences characterizing China call for focused attention on the female middle-aged and elderly population, enhanced weight management, and implementation of targeted preventive and control measures.
Humans ; Osteoarthritis, Knee/epidemiology* ; China/epidemiology* ; Male ; Female ; Middle Aged ; Incidence ; Aged ; Adult ; Prevalence ; Body Mass Index ; Disability-Adjusted Life Years ; Cost of Illness ; Aged, 80 and over ; Sex Factors ; Global Burden of Disease ; Age Factors ; Young Adult ; Quality-Adjusted Life Years

Objective To analyze the hope level and correlative factors in hospitalized pneumoconiosis patients, and to provide suggestions of clinical nursing interventions. Methods The study assessed the hope level and social support of 103 hospitalized pneumoconiosis patients via Henh hope level scale ( Chinese version) and the social support revalued scale ( SSRS) . Results The average score of the hope level of 103 cases was (20. 79 ± 6. 32);45 cases (43. 7%) were at low level, 39 cases (37. 9%) were at average level, and 19 cases were at advanced level. The scores of social support, objective support, subjective support and the using-support degrees were significantly lower than the domestic normative scores (P<0. 01). Patient′s educational level, marital status, family income and social support had positive correlation to the hope levels. However, the disease stage, illness duration, hospitalization time and complications had negative correlation to the hope levels. Conclusions The average score of the hope level is at a low level and correlative to the patient′s educational level, marital status, family income, disease stage, illness duration, hospitalization time and complications.