1.Research progress on prospective memory deficits in patients with traumatic brain injury and their application in the forensic evaluation of mental disability
Wen LI ; Xindi LING ; Chao LIU ; Huiyu FAN ; Xujie ZHANG ; Qinting ZHANG ; Tao TANG
Chinese Journal of Psychiatry 2024;57(8):525-530
In the current landscape of forensic psychiatric evaluation, the use of objective assessment techniques to gauge the extent of mental disability is a relatively unexplored territory. The development and enhancement of these techniques are at the forefront of our research. Daily life ability is a crucial factor in the forensic evaluation of mental disability. Given the profound influence of prospective memory on an individual′s daily life ability, its assessment could hold significant value in this context. This article presents a comprehensive review of studies on prospective memory assessment and the underlying neurophysiological and psychological mechanisms in patients with traumatic brain injuries. Our aim is to delve deeper into the potential application of prospective memory assessment in the forensic evaluation of mental disability, a novel and promising area of research.
2.Research progress on prospective memory deficits in patients with traumatic brain injury and their application in the forensic evaluation of mental disability
Wen LI ; Xindi LING ; Chao LIU ; Huiyu FAN ; Xujie ZHANG ; Qinting ZHANG ; Tao TANG
Chinese Journal of Psychiatry 2024;57(8):525-530
In the current landscape of forensic psychiatric evaluation, the use of objective assessment techniques to gauge the extent of mental disability is a relatively unexplored territory. The development and enhancement of these techniques are at the forefront of our research. Daily life ability is a crucial factor in the forensic evaluation of mental disability. Given the profound influence of prospective memory on an individual′s daily life ability, its assessment could hold significant value in this context. This article presents a comprehensive review of studies on prospective memory assessment and the underlying neurophysiological and psychological mechanisms in patients with traumatic brain injuries. Our aim is to delve deeper into the potential application of prospective memory assessment in the forensic evaluation of mental disability, a novel and promising area of research.
3.Personality Change due to Brain Trauma Caused by Traffic Accidents and Its Assess-ment of Psychiatric Impairment
Huiyu FAN ; Qinting ZHANG ; Tao TANG ; Weixiong CAI
Journal of Forensic Medicine 2016;32(2):100-104
Objective To explore the m ain perform ance of personality change in people w ith m ild psy-chiatric im pairm ents w hich due to the brain traum a caused by traffic accidents and its value in assess-m ent of psychiatric im pairm ent. Methods The condition of personality change of patients w ith traum atic brain injury caused by traffic accident w as evaluated by the Scale of Personality Change Post-traum atic Brain Injury (SPCPTBI). Furtherm ore, the correlation betw een the personality change and the degrees of traum atic brain injury and psychiatric im pairm ent w ere explored. Results In 271 sam ples, 239 (88.2% ) w ith personality changes. A m ong these 239 sam ples, 178 (65.7% ), 46 (17.0% ), 15 (5.5% ) w ith m ild, m oderate and severe personality changes, respectively. The ratio based on the extent of personality changes to the degree of brain traum a w as not significant (P>0.05), but the total score difference betw een the groups w as significant (P<0.05). There w as no statistical significance betw een the m edium and high severity brain traum a groups. The higher degree of personality changes, the higher rank of m ental disabilities. The total score difference of the scale of personality change am ong the different m ild psychiatric im pair-m ent group w as significant (P<0.05). The difference betw een other psychiatric im pairm ent levels had statistical significance (P<0.05) except level 7 and 8. Conclusion The occurrence of personality change due to traum atic brain injury caused by traffic accident w as high. Correlations exist betw een the personality change and the degree of psychiatric im pairm ent. Personality change due to brain traum a caused by traffic accident can be assessed effectively by m eans of SPCPTBI, and the correlation betw een the total score and the extent of traum atic brain injury can be found.
4.Progress on Association between COMT Gene and Violence Behavior in Patients with Schizophrenia
Qinting ZHANG ; Min ZHAO ; Bin XIE
Journal of Forensic Medicine 2014;(3):197-201
The prevalence of violence behavior in patients with schizophrenia is higher than that in common population. Data suggest that genetic factors may play a substantial role for the etiology of the behavior. Among the particular gene polymorphisms that have been considered to be involved in vio-lence behavior, the catechol-O-methyltransferase (COMT) gene had been the focus of recent research. This article reviews the association research between COMT gene and violence behavior in patients with schizophrenia in several aspects: SNP polymorphism of COMT Val158Met and COMT Ala72Ser, haplo-type of COMT gene and DNA methylation of promoter region of COMT gene. The genetic research di-rection is presented for patients with schizophrenia.

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