Objective To explore the application of hydrogen-rich drinking water combined with hydrogen inhalation in marine personnel with hyperuricemia.Methods A total of 110 marine personnel with hyperuricemia who recuperated in the Lintong Rehabilitation and Recuperation Center of Joint Logistic support Force from July 2022 to September 2023 were randomly divided into intervention group and control group,with 55 cases in each group.All the participants were given health education,diet management and exercise management for one month.And the intervention group was additionally given hydrogen-rich drinking water and hydrogen inhalation.Clinical effective rate and the levels of blood uric acid,blood urea nitrogen and serum creatinine were compared between the two groups.Results The clinical effective rate of the intervention group was significantly higher than that in the control group after one month treatment(78.18%[43/55]vs.50.91%[28/55],P<0.05).The levels of blood uric acid,blood urea nitrogen and serum creatinine were significantly decreased after treatment in both groups,and the levels of blood uric acid and serum creatinine in the intervention group were significantly lower than those in the control group(P<0.05).However,there was no satistically significant difference in blood uren nitrogen between before and after intervention.Conclusion The hydrogen-rich drinking water combined with hydrogen inhalation can effectively reduce the level of blood uric acid in marine personnel with hyperuricemia,improving the therapeutic effect and renal function,so it is worthy of further promotion.