Objective To analyze the characteristics in heart,lung and skeletal muscles of patients with post-stroke hemiplegia,and explore the main contributors to the cardiorespiratory fitness(CRF)after stroke with cardiopulmonary exercise testing(CPET).Methods From December,2021 to July,2023,79 eligible stroke patients with hemiplegia were recruited from Shanghai Jing'an District Central Hospital;meanwhile,twelve age-and gender-matched healthy subjects were recruited as controls.All the subjects received CPET.Paired-samples t test or Wilcoxon signed rank test was used to compare the differences of the CPET derived parameters between twelve stroke patients and healthy subjects.Multiple lin-ear regression was used to analyze the main contributors to the CRF of stroke patients with hemiplegia.Results The peak oxygen uptake(VO2peak),anaerobic threshold(AT)/VO2peak%pred(∣t∣>7.027,P<0.001),and O2 pulse peak(Z=-2.433,P<0.05)were lower,and the volume of dead space(VD)/tidal volume(VTpeak)was higher in the patients than in the controls(t=4.217,P<0.01).Multiple linear regression analysis indicated that O2 pulse peak(B=0.461)and AT/VO2peak%pred(B=19.340)were the main contributors to the VO2peak of stroke patients with hemiplegia(P<0.01)after the removal of the interference of age,and AT/VO2peak%pred was the largest contributor.Conclusion The CRF of hemiplegic patients after stroke has decreased,especially for the output volume,the efficiency of gas exchange and aerobic capacity of skeletal muscles.Skeletal muscle aerobic capacity and cardiac blood-pumping function are the main contributors to the CRF,especially the aerobic capacity of skeletal muscles.

Objective To analyze the characteristics in heart,lung and skeletal muscles of patients with post-stroke hemiplegia,and explore the main contributors to the cardiorespiratory fitness(CRF)after stroke with cardiopulmonary exercise testing(CPET).Methods From December,2021 to July,2023,79 eligible stroke patients with hemiplegia were recruited from Shanghai Jing'an District Central Hospital;meanwhile,twelve age-and gender-matched healthy subjects were recruited as controls.All the subjects received CPET.Paired-samples t test or Wilcoxon signed rank test was used to compare the differences of the CPET derived parameters between twelve stroke patients and healthy subjects.Multiple lin-ear regression was used to analyze the main contributors to the CRF of stroke patients with hemiplegia.Results The peak oxygen uptake(VO2peak),anaerobic threshold(AT)/VO2peak%pred(∣t∣>7.027,P<0.001),and O2 pulse peak(Z=-2.433,P<0.05)were lower,and the volume of dead space(VD)/tidal volume(VTpeak)was higher in the patients than in the controls(t=4.217,P<0.01).Multiple linear regression analysis indicated that O2 pulse peak(B=0.461)and AT/VO2peak%pred(B=19.340)were the main contributors to the VO2peak of stroke patients with hemiplegia(P<0.01)after the removal of the interference of age,and AT/VO2peak%pred was the largest contributor.Conclusion The CRF of hemiplegic patients after stroke has decreased,especially for the output volume,the efficiency of gas exchange and aerobic capacity of skeletal muscles.Skeletal muscle aerobic capacity and cardiac blood-pumping function are the main contributors to the CRF,especially the aerobic capacity of skeletal muscles.

Objective To identify one acid‐fasting bacteria isolated from wound secretion of breast abscess .Methods The acid‐fasting strain was identified by the morphological characteristics ,API 20A strips ,classical biochemical reaction ,and 16S rRNA gene sequencing .Results Cells of the strain was anaerobic ,non‐spore‐forming ,pleomorphic ,straight or curved rods ,which Gram and acid‐fast stain both were positive .After incubation for 5 days on sheep blood agar ,colonies were than 2 mm in diameter ,circular , smooth ,entire ,bump ,rice cream‐like withβ‐hemolysis .The 16S rRNA gene sequences were 100% identity to Propionibacterium av‐idum .The API 20A profile was 44365062 with positive Voges‐Proskauer test ,which was also consistent to Propionibacterium avi‐dum .Conclusion The pathogens of breast abscess is Proionibacterium avidum ,which is the first acid‐fasting Propionibacterium re‐ported in China .

Breast Neoplasms ; diagnosis ; Female ; Humans ; Image Processing, Computer-Assisted ; Immunohistochemistry ; Spectrum Analysis