Objective:To assess the current status of geriatrics department development in public general hospitals at or above the second grade in Shandong province.Methods:A cross-sectional survey was conducted from October 27 to November 3, 2023 using a web-based electronic questionnaire to investigate the current status of geriatrics department development in all public general hospitals at or above the second grade across 16 prefecture-level cities in Shandong province.The survey included participation from medical department staff and managers of geriatric medicine departments.Results:Shandong province has 355 public general hospitals at or above the second grade, of which 337 completed the questionnaire.Among these 337 hospitals, 92.28%(311/337)have established geriatric departments, 83.09%(280/337)have set up geriatric clinics, 69.14%(233/337)have independent geriatric wards, and 71.51%(241/337)have implemented comprehensive geriatric assessments(CGA).Regarding the configuration of geriatric departments, 60.24%(203/337)of hospitals met the requirement of having at least 20 ward beds, 34.42%(116/337)met the doctor-to-bed ratio requirement of at least 0.3, and 22.26%(75/337)met the nurse-to-bed ratio requirement of at least 0.6.Only 13 hospitals met all the requirements for geriatric wards, beds, doctors, and nurses, accounting for 3.86%(13/337)of the participating hospitals.Conclusions:The establishment of geriatrics departments in second-grade or higher public general hospitals in Shandong province has surpassed the national target in China ahead of schedule.Most hospitals have established geriatric clinics and wards and have implemented CGA.However, significant challenges remain, including a shortage of ward beds and a lack of medical staff.

Objective:To assess the current status of geriatrics department development in public general hospitals at or above the second grade in Shandong province.Methods:A cross-sectional survey was conducted from October 27 to November 3, 2023 using a web-based electronic questionnaire to investigate the current status of geriatrics department development in all public general hospitals at or above the second grade across 16 prefecture-level cities in Shandong province.The survey included participation from medical department staff and managers of geriatric medicine departments.Results:Shandong province has 355 public general hospitals at or above the second grade, of which 337 completed the questionnaire.Among these 337 hospitals, 92.28%(311/337)have established geriatric departments, 83.09%(280/337)have set up geriatric clinics, 69.14%(233/337)have independent geriatric wards, and 71.51%(241/337)have implemented comprehensive geriatric assessments(CGA).Regarding the configuration of geriatric departments, 60.24%(203/337)of hospitals met the requirement of having at least 20 ward beds, 34.42%(116/337)met the doctor-to-bed ratio requirement of at least 0.3, and 22.26%(75/337)met the nurse-to-bed ratio requirement of at least 0.6.Only 13 hospitals met all the requirements for geriatric wards, beds, doctors, and nurses, accounting for 3.86%(13/337)of the participating hospitals.Conclusions:The establishment of geriatrics departments in second-grade or higher public general hospitals in Shandong province has surpassed the national target in China ahead of schedule.Most hospitals have established geriatric clinics and wards and have implemented CGA.However, significant challenges remain, including a shortage of ward beds and a lack of medical staff.

Systemic light-chain(AL)amyloidosis has an insidious onset and diverse clinical manifestations with high early mortality and can be easily overlooked or misdiagnosed in the elderly.Early diagnosis and deep remission are critical for the long-term survival of AL amyloidosis patients.This article provides a systematic review of the current status of treatment and progress in new drugs for AL amyloidosis.

OBJECTIVE: To establish a digital subtraction angiography (DSA) information management and image analysis system to realize scientific management of DSA image information and efficient processing of image data. METHODS: Based on Java Web under Windows 7 environment, a dynamic Browser/Server mode system was constructed by JSP and Servlet on the network. Eclipse and MySQL were used as development tool and database development platform. Tomcat network information service was used as application server. Matlab codes were embedded to analyze DSA image. RESULTS: The system consists of five modules:image information management, image processing, image analysis, advanced retrieval and clinical data management. It may complete such process as storing, deleting, saving, analyzing of DSA image and basic information of patients. CONCLUSIONS The main interface of the system is user-friendly and easy to operate. The system will be helpful to the clinical, teaching and scientific research work related to DSA.
Angiography, Digital Subtraction ; statistics & numerical data ; Databases, Factual ; Humans ; Indonesia ; Information Management ; Internet ; Software ; User-Computer Interface

Objective To explore the entrainment effect of different light regimens on the circadian rhythms of peripheral blood immune cells in mice .Methods One hundred and forty-four male C57BL/6 mice were kept under the 12 h-light and 12 h-dark cycle for 4 weeks.Then, the animals were randomly divided into 3 groups.The 24 animals in group 1 were treated with the former light regimen , the 60 animals in group 2 were kept in the light regimen of phase advance 12 hours, simulating eastward flight, and another 60 animals in group 3 were kept in the light regimen of phase delay 12 hours, simulating westward flight.Peripheral blood samples of the animals in group 1 were collected respectively one day before and 21 days after changes of light regimens, and blood samples of the animals in group 2 and 3 were collected on different days (i.e.day 2, 4, 7, 14 and 21) after changes of light regimens .Peripheral blood samples were taken at 4 different timepoints in 24 hours ( i.e.9 :00, 15:00, 21 :00 and 3 :00).Detections were made in immune cells , including the numbers of leukocytes, the percentage of lymphocytes , the percentage of CD4 +lymphocytes, the percentage of CD8 +lymphocytes, as well as monocyte and granulocyte counts .Finally, the circadian rhythms of differentimmune cells were evaluated in the animals of different groups .Results The immune cells in the C57BL/6 mice displayed different circadian rhythms under the 12 h-light and 12 h-dark cycle for 4 weeks.Under the new light regimens, the circadian rhythms of immune cells were entrained .It took 2 weeks for the animals of the simulated westward flight phase delay group to entrain the circadian rhythm , while the rate of entrainment for the animals of the simulated eastward flight phase delay group was 3 weeks.Conclusions Under the 12 h-light and 12 h-dark cycle, immune cells in the peripheral blood displayed a rise and fall circadian rhythm , which might facilitate the balance of the immune system .However, under the new light regimens, the circadian rhythms of different immune cells in the peripheral blood were entrained , with the entrainment rate of immune cells in the phase delay group being faster than that of the phase advance group .

Objective To evaluate mental workload of the pilots in different phases of simulated carrier flight for enhancing flight performance and ensuring flight safety.Methods Ten male pilots participated in the study.The subjective mental workload of pilots was rated by modified multidimensional National Aeronautics and Space Administration task load index (NASA-TLX) questionnaire after the traffic pattern flights in simulator.Results The overall mental workload rating scores in the take-off,downwind leg cruising,base turn and the final approach landing phases were 54.22±16.74,40.68±17.76,61.08±17.80,86.64±6.37 respectively.The pilot's mental workload in landing phase was significant higher than that in other three phases (F=15.613,P＜ 0.01).So did the score of mental demand tested by six dimensions of the NASA-TLX questionnaire (F=34.944,P＜0.01).The scores of temporal demand and effort during the landing phase were significant higher than those during the take-off phase and downwind leg cruising phase (F=5.653,3.344,P＜0.01 or 0.05).The scores of physical demand,performance and frustration had no significant differences among 4 flight phases.Conclusions Analysis of the TLX scores reveals that the carrier pilots have the highest subjective mental workload in landing phase as compared with that in other phases,and such significance may relate to the extent of mental demand,temporal demand and effort.

Objective To study the dynamic response of the head and neck for the pilots during arrested deck landing for prevention,diagnosis and treatment of head and neck injuries.Methods The multi-rigid-body model of the pilot in driving posture was established by abstracting head and neck physiological anatomy,cervical vertebra stress characteristics and cervical muscle tension characteristics.The passive neck properties were modeled by spring-damper paralleling link.Results A head and neck dynamic response model was established by taking the arrested motion data as the input.Also,the simulation architecture,simulation process and validation methods were demonstrated.The double thread simulation process of dynamics and biomechanics were established,and the related factors that affect the dynamic response were included in the simulation process.The verification method of the simulation model was described and the factors affecting the accuracy of modeling were analyzed.Conclusions The factors affecting the reliability of simulation and the accuracy of the model are varied.Accelerating curve of head is affected not only by physiological structure of neck,initial velocity of aircraft landing,weight of plane and property of arrested device,but also by the position of arrested device and attitude of aircraft during arresting.The mathematical simulation could be a feasible tool of studying the dynamic response mechanism of head and neck in arrested deck landing.

Objective To explore the entrainment effect of different light regimens on the circadian rhythms of peripheral blood immune cells in mice .Methods One hundred and forty-four male C57BL/6 mice were kept under the 12 h-light and 12 h-dark cycle for 4 weeks.Then, the animals were randomly divided into 3 groups.The 24 animals in group 1 were treated with the former light regimen , the 60 animals in group 2 were kept in the light regimen of phase advance 12 hours, simulating eastward flight, and another 60 animals in group 3 were kept in the light regimen of phase delay 12 hours, simulating westward flight.Peripheral blood samples of the animals in group 1 were collected respectively one day before and 21 days after changes of light regimens, and blood samples of the animals in group 2 and 3 were collected on different days (i.e.day 2, 4, 7, 14 and 21) after changes of light regimens .Peripheral blood samples were taken at 4 different timepoints in 24 hours ( i.e.9 :00, 15:00, 21 :00 and 3 :00).Detections were made in immune cells , including the numbers of leukocytes, the percentage of lymphocytes , the percentage of CD4 +lymphocytes, the percentage of CD8 +lymphocytes, as well as monocyte and granulocyte counts .Finally, the circadian rhythms of differentimmune cells were evaluated in the animals of different groups .Results The immune cells in the C57BL/6 mice displayed different circadian rhythms under the 12 h-light and 12 h-dark cycle for 4 weeks.Under the new light regimens, the circadian rhythms of immune cells were entrained .It took 2 weeks for the animals of the simulated westward flight phase delay group to entrain the circadian rhythm , while the rate of entrainment for the animals of the simulated eastward flight phase delay group was 3 weeks.Conclusions Under the 12 h-light and 12 h-dark cycle, immune cells in the peripheral blood displayed a rise and fall circadian rhythm , which might facilitate the balance of the immune system .However, under the new light regimens, the circadian rhythms of different immune cells in the peripheral blood were entrained , with the entrainment rate of immune cells in the phase delay group being faster than that of the phase advance group .

Objective To evaluate mental workload of the pilots in different phases of simulated carrier flight for enhancing flight performance and ensuring flight safety.Methods Ten male pilots participated in the study.The subjective mental workload of pilots was rated by modified multidimensional National Aeronautics and Space Administration task load index (NASA-TLX) questionnaire after the traffic pattern flights in simulator.Results The overall mental workload rating scores in the take-off,downwind leg cruising,base turn and the final approach landing phases were 54.22±16.74,40.68±17.76,61.08±17.80,86.64±6.37 respectively.The pilot's mental workload in landing phase was significant higher than that in other three phases (F=15.613,P＜ 0.01).So did the score of mental demand tested by six dimensions of the NASA-TLX questionnaire (F=34.944,P＜0.01).The scores of temporal demand and effort during the landing phase were significant higher than those during the take-off phase and downwind leg cruising phase (F=5.653,3.344,P＜0.01 or 0.05).The scores of physical demand,performance and frustration had no significant differences among 4 flight phases.Conclusions Analysis of the TLX scores reveals that the carrier pilots have the highest subjective mental workload in landing phase as compared with that in other phases,and such significance may relate to the extent of mental demand,temporal demand and effort.

Objective To study the dynamic response of the head and neck for the pilots during arrested deck landing for prevention,diagnosis and treatment of head and neck injuries.Methods The multi-rigid-body model of the pilot in driving posture was established by abstracting head and neck physiological anatomy,cervical vertebra stress characteristics and cervical muscle tension characteristics.The passive neck properties were modeled by spring-damper paralleling link.Results A head and neck dynamic response model was established by taking the arrested motion data as the input.Also,the simulation architecture,simulation process and validation methods were demonstrated.The double thread simulation process of dynamics and biomechanics were established,and the related factors that affect the dynamic response were included in the simulation process.The verification method of the simulation model was described and the factors affecting the accuracy of modeling were analyzed.Conclusions The factors affecting the reliability of simulation and the accuracy of the model are varied.Accelerating curve of head is affected not only by physiological structure of neck,initial velocity of aircraft landing,weight of plane and property of arrested device,but also by the position of arrested device and attitude of aircraft during arresting.The mathematical simulation could be a feasible tool of studying the dynamic response mechanism of head and neck in arrested deck landing.