Objective To explore the mediating effect of the burden on primary caregivers of patients with schizophrenia between affiliated stigma and quality of life.Methods A convenience sampling method was used to select 220 primary caregivers of patients with schizophrenia as study subjects.A general information questionnaire,the Zarit Burden Interview(ZBI),the Perceived De-valuation-Discrimination Scale(PDD),and the World Health Organization Quality of Life-BREF(WHOQOL-BREF)were employed for the survey.Pearson correlation analysis was used for correla-tion analysis,and Amos 26.0 software was used to construct a structural equation model.The media-ting effect was tested using the Bootstrap method.Results The score for the burden on primary care-givers of patients with schizophrenia was(38.68±14.80),indicating a moderate level.The score for affiliated stigma was(32.20±8.23),suggesting the presence of affiliated stigma.The score for quality of life was(76.92±20.72),also at a moderate level.Pearson correlation analysis revealed a positive correlation between caregiver burden and affiliated stigma(r=0.311,P＜0.01),a negative correlation between caregiver burden and quality of life(r=-0.349,P＜0.01),and a negative correlation between affiliated stigma and quality of life(r=-0.249,P＜0.01).Caregiver burden acted as a mediating variable between affiliated stigma and quality of life,with a total effect value of-0.317,a direct effect value of-0.269,and a mediating effect value of-0.048.The mediating effect accounted for 15.14％of the total effect.Conclusion The burden on primary caregivers of patients with schizophrenia plays a partial mediating role between affiliated stigma and quality of life.Medical staff should implement effective intervention measures to reduce caregivers' affiliated stigma and caregiving burden,thereby improving their quality of life.

Objective? To investigate the effect of Team collaboration management program on the metabolic syndrome in schizophrenic patients. Methods? From March 2017 to March 2018, the schizophrenic patients with metabolic syndrome who were admitted in Shanghai Mental Health Center Affiliated to Shanghai Jiao Tong University School of Medicine were selected as the participants of this study and divided into observation group (n=45) and control group (n=47) according to the time of admission. The two groups were both given routine treatment and nursing care in psychiatric department. Besides of that, the team collaboration management program was implemented in the observation group. Assessments were done before intervention and 16 weeks after intervention using related metabolic parameters, the Brief Scale of World Health Organization Quality of Life (WHOQOL-BREF) and the Positive and Negative Symptoms Scale (PANSS). Results? There was no significant difference in metabolic parameters, WHOQOL-BREF and PANSS scores between the two groups before intervention (P＞0.05). After 16 weeks of intervention, patients' fasting blood sugar level, body weight, waist circumference, triglyceride, high density lipoprotein and systolic pressure in the observation group were lower than those in the control group, and the difference was statistically significant (P＜0.05). The scores of"physical health" and "psychological function" in WHOQOL-BREF in the observation group were higher than those in the control group, meanwhile, the scores of "positive and general pathological symptoms" in PANSS in the observation group were lower than those in the control group, both with statistical significance (P＜0.05). Conclusions? Team collaboration management program can help controlling the related metabolic parameters of the schizophrenic patients with metabolic syndrome effectively, improve their quality of life and promote recovery from their mental symptoms.

Objective To explore the disease management experience of patients with depression and their caregivers.Methods In February to July 2017, qualitative research method was adopted, and depth interviews were conducted among 16 patients with depression and 12 caregivers.Results After analysis, 4 themes were extracted. Emotion management: the patients and their caregivers were void of knowledge of the disease which affects the identification of emotional symptoms,and they were also deficient in methods and skills of emotional regulation. Drug management: depression emotion affected the self-management of drugs. The comprehending deviation of drug effects and adverse reaction will affect the patients to continue take medicine. Role management: patients had misunderstood the maintenance of social role function, and their attitude towards the maintenance of a good social role function was also lack of continuity. Social resources and utilization: supporting social resources were insufficient, and social resources cannot be effectively utilized. Conclusions There are some difficulties in the disease management of patients with depression, so patients and their caregivers should learn disease-related knowledge and management skills. At the same time, social support and help in multiple ways are required.

OBJECTIVE To investigate the indication and applicability of participatory research in medical workers′ hospital infection education.METHODS The medical workers in our hospital were divided into two groups with 315 people each.One group was investigated with questionnaires anonymously and then arranged the key issue and the strategy with participatory research.The other group was with the same questionnaires anonymously 3 months later.RESULTS There was a statistics difference between two groups in the comprehension of hospital infection knowledge,hands hygiene,the ratio of wash hands with standard process(P

OBJECTIVE To investigate antibiotic resistance and antibiotics usage of meticillin-resistant Staphylococcus(MRS) and provide reference evidence in antibiotics using.METHODS Antibiotic susceptibility test was performed by biological assay system of VITEK-2.Design questionnaires to get the message of the categories,days,effects of antibacterial drug used.RESULTS Drug sensitive ratio to vancomycin,nitrofurantoin,quinupristin-dalfopristin,linezolid were all over 90.00%.The resistant ratios to some antibacterials in MRS were higher than in meticillin-sensitive Staphylococcus(MSS).The categories of antibacterials used after Staphylococcus species detection were more than before.63.01% patients′ medication was determined by antibiotic susceptibility test.Staphylococcus isolated ratio was 43.75% after antibacterial drug used.CONCLUSIONS The status of MRS is very serious.We should pay more attention to the identification and report of resistant strains and it is important to supervise Staphylococcus efficiently and medication by antibiotic susceptibility test.