1.Analysis of the Effectiveness of Medical Quality Improvement in Cosmetic Injection Procedures in Chengdu from 2022 to 2024
Medical Journal of Peking Union Medical College Hospital 2026;17(2):566-573
To evaluate the effectiveness of medical quality improvement in the cosmetic injection industry in Chengdu. Based on A total of 378 medical aesthetic institutions were surveyed, including 58 plastic surgery hospitals, 111 medical aesthetic outpatient departments, and 209 medical aesthetic clinics. Among them, 43 institutions were surveyed in 2022, 287 in 2023, and 48 in 2024. From 2022 to 2024, overall compliance regarding institutional and personnel qualifications was good, with low detection rates for related issues. Compared with 2022, the quality of cosmetic injection medical services significantly improved in 2023 and 2024. The detection rates of non-compliance or substandard practices significantly decreased in areas including quality and safety management of injectable fillers for aesthetic purposes, quality and safety management of injectable botulinum toxin type A, medical quality management of injection procedures, injection medical record management, and emergency management. The improvement in many indicators was more pronounced in 2024( Under the multi-departmental "comprehensive investigation-supervision-training" model adopted by the Chengdu Plastic and Aesthetic Medicine Quality Control Center, the medical quality of cosmetic injection procedures in the city showed continuous improvement from 2022 to 2024, with a significant downward trend in the detection rates of relevant non-compliant issues. The reported incidence of injection-related complications during the same period was lower than the national target. This model provides a reference for implementing effective quality control in the plastic and aesthetic medicine specialty.
2.Changes in the number and biological ability of endothelial progenitor cells from peripheral blood of patients with systemic lupus erythematosus (SLE)
Peimei ZHOU ; Yonghong LU ; Xia XIONG ; Xiaoyun CHENG ; Yanjun ZHU ; Shihua ZENG ; Tao CHEN ; Qingbiao WA ; Qi CAI ; Qianming CHEN ; Cunhuo JIANG
Chinese Journal of Dermatology 2010;43(10):698-701
Objective To analyze the changes in number and biological ability of endothelial progenitor cells (EPCs) from peripheral blood of SLE patients. Methods Mononuclear cells (MNCs) were isolated by Ficoll density gradient centrifugation from peripheral blood of 20 female SLE patients and 20 healthy female controls. EPCs were identified by double staining using antibodies to CD34 and CD133, or antibodies to CD133 and vascular endothelial growth factor receptor 2 (VEGFR2). Phycoerythrin (PE) conjugated antiCD34, fluorescein isothiocyanate (FITC) conjugated anti-CD133 and APC conjugated anti-VEGFR2 antibodies were used in a three color flow cytometric analysis to determine the percentage of EPCs in peripheral MNCs.The proliferation and migration ability of EPCs were measured by MTT assay and modified millicell chamber assay, respectively. The adhesion activity of EPCs was evaluated by counting the number of adherent cells.Results The percentage and proliferation rate of EPCs in peripheral MNCs from female SLE patients were significantly lower than those from the healthy controls(4.49% ± 1.66% vs 20.81% ± 4.14%, 23.11% ± 3.16%vs 35.65% ± 1.74%, both P ＜ 0.01 ). The migration and adhesion ability of EPCs from SLE patients was impaired compared with those from the healthy controls (12.00 ± 2.12 vs 23.60 ± 3.0 cells/field, 22.43 ± 4.43vs 36.43 ± 3.69 cells/filed, both P ＜ 0.01 ). Conclusion There is a decrease in the number and an impairment in biological ability of EPCs in SLE patients.
3.Frequencies of Mutations at Glycophorin-A Locus of Erythrocytes in Patients with High Arsenic Coal Poisoning
Haihuan XU ; Xinjiang ZHANG ; Ning FANG ; Hui DU ; Yunshu ZHOU ; Wei YUAN ; Ling JIANG ; He XIAO ; Qingbiao WA ; Mingliang ZHAO
Chinese Journal of Dermatology 2003;0(12):-
Objectives To observe the frequencies of mutations at glycophorin A(GPA)of erythro-cytes in patients with high arsenic coal poisoning(HACP)in comparison with normal controls.Methods The peripheral erythrocytes were isolated and immunolabelled,and were detected by flow cytometry in40patients and18normal adults.Results The mutation frequencies(MF)were(21.23?13.97)?10 -6 for type NN,(33.13?25.72)?10 -6 for type NO,(110.90?63.58)?10 -6 for type MM,and(20.35?21.26)?10 -6 for type MO of erythrocytes in patients with HACP,which were significantly higher than those in normal controls.The mutation frequencies were(31.50?16.13)?10 -6 for type NN,(54.50?38.13)?10 -6 for type NO,(159.33?66.22)?10 -6 for type MM,and(45.16?12.69)?10 -6 for type MO of erythrocytes in tumor group of HACP patients,which were significantly higher than those of non-tumor group of the patients.Conclusions Arsenic poisoning may induce the mutation at the glycophorin-A locus of erythrocytes,sug-gesting that arsenic may be one of potential mutagens.GPA-MF may serve as a parameter for the detection of patients with HACP.
4.Detection of Microsatellite Instability in Lesions from Patients with Coal Arsenic Poisoning
Wei YUAN ; Xinjiang ZHANG ; Qingbiao WA ; Tingming ZHENG ; He XIAO ; Hui DU ; Yunshu ZHOU
Chinese Journal of Dermatology 1994;0(02):-
0.05). Conclusions MSI and LOH may play a certain role in the carcinogenesis and progression of arsenic-induced skin lesions.
Result Analysis
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