Objective To analyze the occurrence status and characteristics of occupational needle-stick injuries among medical workers base on surveillance data and retrospective survey.Methods The data of occupational exposure reported by various depart-ments were collected and sorted out from January 1,2011 to March 31,2016.The self-designed occupational sharp instrument inju-ries questionnaire was adopted to collect the sharp instrument injuries situation from April 1-15,2016.Then the analysis was per-formed by adopting the SPSS20.0 software.Results The surveillance data analysis results showed that the incidence rate of occu-pational needle-stick injuries was 11.77%,the sex of medical staffs suffering from the needle-stick injuries was dominated by fe-males,the age was mainly under 25 years old,the type of work was mainly nurse and practicing nurse;the retrospective investigation found that 44.54% of medical staffs suffered from the stick injuries at the same time period.The occurrence risk of needle-stick in-jury had no statistical difference between the male and female medical staffs(χ2 =2.266,P=0.132),the occurrence risk was the highest in the 25-40 years old group,the occurrence rate of nurse stick-injury was 48.40%,which of doctors was 43.50%.Conclu-sion The report awareness after suffering from occupational needle-stick injury among medical staffs urgently needs to be strengthened,and doctors also are the high risk population of occupational needle-stick injury.