Objective To investigate the effects of the laparoscopic surgery and open surgery on the postoperative intestinal function recovery time in elderly patients with colorectal cancer(CRC).Methods 66 elderly patients with CRC and treated in the 2nd People's Hospital of Kunming from January 2021to July 2022 were chosen and divided into the control group(n = 33)and the study group(n = 33)according to different operation ways.And the postoperative bowel function recovery time,radical,complications and surgical index were compared between the two groups.Results The recovery time of intestinal function in the study group was significantly shorter than that in the control group(P<0.05),but there was no significant difference in radical indicators between the two groups(P>0.05).The incidence of complications in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).The operation time of the study group was longer than that of the control group and there was the statistically significant difference(P<0.05),while the bleeding was less than that of the control group and there was the statistically significant difference(P<0.05).Conclusion Compared with the open surgery,laparoscopic surgery can more effectively shorten the recovery time of postoperative intestinal function,reduce the incidence of complications and intraoperative blood loss in elderly patients with CRC.Although there is no significant difference between two kinds of operation mode in terms of radical,it should be considered when it is applied in the specific operation time and other factors.

Objective:To provide warning information for early renal injury in pilots by investigating the relationship between serum cystatin C (Cys-C) level and renal blood flow parameters in healthy pilots.Methods:A total of 347 military pilots who underwent annual physical examination in the Air Service Department of the 960th Hospital of Joint Logistics Support Force from July of 2019 to December of 2021 were selected as the pilot group, and 347 healthy subjects who were in same age span and examined at same period were selected as the control group. Color Doppler flow imaging was used to qualitatively analyze renal artery blood flow parameters, including the peak systolic velocity (PSV), end-diastolic blood flow velocity (EDV) and resistance index (RI) of the main renal artery, segmental artery and interlobar arteries. The serum urea nitrogen, serum creatinine and uric acid of subjects were measured. Both pilot group and the control group were divided into 21-30 years old, 31-40 years old and 41-50 years old groups. According to the median level of serum Cys-C, the pilots were divided into high Cys-C group and low Cys-C group. The Cys-C level and renal blood flow parameters of each group were compared, and the correlation between Cys-C level and renal blood flow parameters of pilots was analyzed.Results:There were no significant differences on serum Cys-C level between the pilot group and the control group at all ages (all P>0.05). There was a significant difference on Cys-C levels among the pilots of different ages ( H=8.24, P=0.045). There was no significant difference in Cys-C levels among control groups at different ages ( P>0.05). The levels of endogenous creatinine clearance and uric acid in the high Cys-C group were higher than those in the low Cys-C group, and the differences were significant ( Z=-4.17, -2.98, P<0.001, =0.003). The EDV of main renal artery in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( t=4.82, P=0.021). The EDV of interlobar arteries in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( Z=-5.48, P=0.030). Correlation analysis showed that the Cys-C level of pilots was positively correlated with age, flying hours and uric acid level ( r=0.381, 0.165, 0.359, P=0.001, 0.002, 0.003). Cys-C level was negatively correlated with EDV of main renal artery and interlobar arteries ( r=-0.306, -0.321, P=0.048, 0.024), and positively correlated with RI of main renal artery ( r=0.417, P=0.029). Conclusions:The serum Cys-C of pilots could reflect certain basic data of renal function and is hopeful to provide warning for early renal injury due it correlated to the EDV of main renal artery and interlobar arteries and the RI of main renal artery.

Objective:To provide warning information for early renal injury in pilots by investigating the relationship between serum cystatin C (Cys-C) level and renal blood flow parameters in healthy pilots.Methods:A total of 347 military pilots who underwent annual physical examination in the Air Service Department of the 960th Hospital of Joint Logistics Support Force from July of 2019 to December of 2021 were selected as the pilot group, and 347 healthy subjects who were in same age span and examined at same period were selected as the control group. Color Doppler flow imaging was used to qualitatively analyze renal artery blood flow parameters, including the peak systolic velocity (PSV), end-diastolic blood flow velocity (EDV) and resistance index (RI) of the main renal artery, segmental artery and interlobar arteries. The serum urea nitrogen, serum creatinine and uric acid of subjects were measured. Both pilot group and the control group were divided into 21-30 years old, 31-40 years old and 41-50 years old groups. According to the median level of serum Cys-C, the pilots were divided into high Cys-C group and low Cys-C group. The Cys-C level and renal blood flow parameters of each group were compared, and the correlation between Cys-C level and renal blood flow parameters of pilots was analyzed.Results:There were no significant differences on serum Cys-C level between the pilot group and the control group at all ages (all P>0.05). There was a significant difference on Cys-C levels among the pilots of different ages ( H=8.24, P=0.045). There was no significant difference in Cys-C levels among control groups at different ages ( P>0.05). The levels of endogenous creatinine clearance and uric acid in the high Cys-C group were higher than those in the low Cys-C group, and the differences were significant ( Z=-4.17, -2.98, P<0.001, =0.003). The EDV of main renal artery in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( t=4.82, P=0.021). The EDV of interlobar arteries in high Cys-C group was lower than that in low Cys-C group, and the difference was significant ( Z=-5.48, P=0.030). Correlation analysis showed that the Cys-C level of pilots was positively correlated with age, flying hours and uric acid level ( r=0.381, 0.165, 0.359, P=0.001, 0.002, 0.003). Cys-C level was negatively correlated with EDV of main renal artery and interlobar arteries ( r=-0.306, -0.321, P=0.048, 0.024), and positively correlated with RI of main renal artery ( r=0.417, P=0.029). Conclusions:The serum Cys-C of pilots could reflect certain basic data of renal function and is hopeful to provide warning for early renal injury due it correlated to the EDV of main renal artery and interlobar arteries and the RI of main renal artery.

Objective:To evaluate the value of conventional ultrasound, shear wave elastography and thyroglobulin antibody in the differential diagnosis of benign and malignant thyroid nodules in pilots by Logistic regression model.Methods:The cohort study was used. The clinical data of pilots with thyroid nodules who were admitted to the 960th Hospital of the Joint Logistics Support Force from January of 2010 to May of 2022 were collected, including thyroglobulin antibody results and ultrasound images. The pathological results were used as the gold standard to establish a binary Logistic regression model and evaluate its ability to predict benign and malignant nodules.Results:Seventy-two pilots were included, all were male, with 22-55 years old and 75-5 600 h flying hours. A total of 85 nodules were detected. Among them, 48 nodules were benign nodules, including 34 nodular goiters, 10 adenomas, and 4 thyroid cystic nodules. There were 37 malignant nodules, all of which were papillary carcinomas. A total of 4 statistically significant characteristic variables were screened out, including thyroid nodule morphology, microcalcification, serum thyroglobulin antibody, and maximum elastic modulus. The sensitivity, specificity and accuracy of Logistic regression model in predicting benign and malignant thyroid nodules was 83.9%, 79.6% and 81.5%, respectively. The area under the receiver operating characteristic curve was 0.908 (95% CI: 0.850-0.966). Conclusions:The Logistic regression model established by shear wave elastography combined with thyroglobulin antibody has high diagnostic value. It is helpful to the differential diagnosis of benign and malignant thyroid nodules in pilots.

Objective:To evaluate the value of conventional ultrasound, shear wave elastography and thyroglobulin antibody in the differential diagnosis of benign and malignant thyroid nodules in pilots by Logistic regression model.Methods:The cohort study was used. The clinical data of pilots with thyroid nodules who were admitted to the 960th Hospital of the Joint Logistics Support Force from January of 2010 to May of 2022 were collected, including thyroglobulin antibody results and ultrasound images. The pathological results were used as the gold standard to establish a binary Logistic regression model and evaluate its ability to predict benign and malignant nodules.Results:Seventy-two pilots were included, all were male, with 22-55 years old and 75-5 600 h flying hours. A total of 85 nodules were detected. Among them, 48 nodules were benign nodules, including 34 nodular goiters, 10 adenomas, and 4 thyroid cystic nodules. There were 37 malignant nodules, all of which were papillary carcinomas. A total of 4 statistically significant characteristic variables were screened out, including thyroid nodule morphology, microcalcification, serum thyroglobulin antibody, and maximum elastic modulus. The sensitivity, specificity and accuracy of Logistic regression model in predicting benign and malignant thyroid nodules was 83.9%, 79.6% and 81.5%, respectively. The area under the receiver operating characteristic curve was 0.908 (95% CI: 0.850-0.966). Conclusions:The Logistic regression model established by shear wave elastography combined with thyroglobulin antibody has high diagnostic value. It is helpful to the differential diagnosis of benign and malignant thyroid nodules in pilots.

As a non-atherosclerotic disease in the extracranial segment of the carotid artery, carotid web is a ridge-like intraluminal protrusion beyond the bifurcation of the posterior wall of the carotid artery bulb. Carotid web also has been referred to as an atypical variant of fibromuscular dysplasia. In recent years, more and more studies indicate that carotid web is a rare but important risk factor for ischemic stroke. In order to accurately diagnose carotid artery web, implement targeted intervention and treatment for ischemic stroke caused by carotid web, the authors summarized the recent advances in carotid web and ischemic stroke.

Objective To explore the effects of real-time shear wave elastography (SWE) on diagnosing benign and malignant thyroid nodules in pilots . Methods Fifty-two pilots were diagnosed as thyroid nodules (60 nodules) in 456th Hospital of People's Liberation Army from May 2014 to May 2017 .They were checked by real -time shear wave elastography and the Young＇s moduli of nodules and normal thyroid tissues were recorded .The Young＇s modulus of patients' normal thyroid tissues was taken as control value and was compared to that of thyroid nodules .By referring to the pathological examination result as the gold stand ,the receiver operating characteristic (ROC ) curve was plotted to determine if the thyroid nodules were benign or malignant in SWE diagnosis .The area under the ROC curve (AUC) was compared to determine the best diagnostic boundary . Results Out of 52 cases of thyroid nodules ,43 cases (48 nodules) were benign lesions .The pathological types included nodular goiter (n＝ 33) and adenomas (n＝ 15) .There were 9 cases of malignant lesions (12 nodules) including papillary carcinoma (n＝ 10) and small papillary carcinoma (n＝ 2) .The maximum ,average and minimum Young's modulus values showed significant difference between control group and those with thyroid adenoma ,nodular goiter and thyroid malignant tumor (F＝258 .19 ,268 .39 ,421 .84 ,P＜0 .01) .The mean ,maximum and minimum Young's modulus values of malignant nodules were (58 .68 ± 9 .27) kPa ,(78 .64 ± 11 .53) kPa and (38 .51 ± 5 .81) kPa respectively , and were higher than those of benign thyroid nodules (41 .48 ± 5 .69) kPa , (52 .23 ± 7 .71 ) kPa , (31 .51 ± 2 .47) kPa .The differences had statistical significance (t＝8 .16 ,9 .55 ,6 .44 , P＜0 .01) .The AUC corresponding to the maximum ,average and minimum Young's modulus value was 0 .929 , 0 .863 and 0 .798 respectively .The best diagnostic efficiency was at the maximum Young's modulus in the nodule and its diagnostic threshold was 54 .42 kPa . Conclusions The Young's modulus of benign thyroid nodules is smaller than that of malignant nodules in pilots .Applying the maximum value of the Young's modulus enables better diagnosis accuracy than using its average or minimum value in determining malignant thyroid nodules .The quantitative SWE is helpful for diagnosing benign and malignant thyroid nodules in pilots .

Objective To explore the effects of real-time shear wave elastography (SWE) on diagnosing benign and malignant thyroid nodules in pilots . Methods Fifty-two pilots were diagnosed as thyroid nodules (60 nodules) in 456th Hospital of People's Liberation Army from May 2014 to May 2017 .They were checked by real -time shear wave elastography and the Young＇s moduli of nodules and normal thyroid tissues were recorded .The Young＇s modulus of patients' normal thyroid tissues was taken as control value and was compared to that of thyroid nodules .By referring to the pathological examination result as the gold stand ,the receiver operating characteristic (ROC ) curve was plotted to determine if the thyroid nodules were benign or malignant in SWE diagnosis .The area under the ROC curve (AUC) was compared to determine the best diagnostic boundary . Results Out of 52 cases of thyroid nodules ,43 cases (48 nodules) were benign lesions .The pathological types included nodular goiter (n＝ 33) and adenomas (n＝ 15) .There were 9 cases of malignant lesions (12 nodules) including papillary carcinoma (n＝ 10) and small papillary carcinoma (n＝ 2) .The maximum ,average and minimum Young's modulus values showed significant difference between control group and those with thyroid adenoma ,nodular goiter and thyroid malignant tumor (F＝258 .19 ,268 .39 ,421 .84 ,P＜0 .01) .The mean ,maximum and minimum Young's modulus values of malignant nodules were (58 .68 ± 9 .27) kPa ,(78 .64 ± 11 .53) kPa and (38 .51 ± 5 .81) kPa respectively , and were higher than those of benign thyroid nodules (41 .48 ± 5 .69) kPa , (52 .23 ± 7 .71 ) kPa , (31 .51 ± 2 .47) kPa .The differences had statistical significance (t＝8 .16 ,9 .55 ,6 .44 , P＜0 .01) .The AUC corresponding to the maximum ,average and minimum Young's modulus value was 0 .929 , 0 .863 and 0 .798 respectively .The best diagnostic efficiency was at the maximum Young's modulus in the nodule and its diagnostic threshold was 54 .42 kPa . Conclusions The Young's modulus of benign thyroid nodules is smaller than that of malignant nodules in pilots .Applying the maximum value of the Young's modulus enables better diagnosis accuracy than using its average or minimum value in determining malignant thyroid nodules .The quantitative SWE is helpful for diagnosing benign and malignant thyroid nodules in pilots .

Objective To establish the optimum syndrome classification method by using the technology of modern TCM diagnosis and artificial intelligence analysis method for menopausal syndrome differentiation of TCM. Methods Diagnostic information of menopausal syndrome patients was collected and syndromes were classified according to TCM syndrome differentiation standard. Three kinds of common data mining classification algorithm, Bayesian network, K-nearest neighbors and support vector machine, were used for analysis on information data of the four methods of diagnosis of menopausal syndrome.Results The time, classification accuracy, coverage rate and margin curve of establishing TCM syndrome model by the three kinds of algorithm methods under the circumstances of same training and data. The influence of the number of training samples of 3 kinds of algorithm methods was analyzed, and the model established by the three kinds of algorithms was evaluated.Conclusion Bayesian network algorithm is better than the other two methods in the menopausal syndrome classification effect.

Objective To analyze the relationship between the level of serum homocysteine and cerebral artery stenosis in cerebral infarction patients.Methods Clinical data from 165 cerebral infarction patients who had been done cerebral angiography examination were analyzed.According to the level of serum homocysteine,the patients were divided into 5.0-15.0 μmol/L group,15.1-20.0 μmol/L group and above 20.1 μmol/L group.Other risk fac-tors including age,gender,blood pressure,blood lipid and blood glucose were recorded.The number of cerebral vascu-lar stenosis in different parts of brain were analyzed,and then make a decision of the relationship between the level of serum homocysteine and cerebral artery stenosis,as well as the other risk factors.Results Among 165 cases,74 cases (48.15%)came from 5.0-15.0 μmol/L group and the number of stenosal cerebral vascular was 36strips,50 cases (30.12%)came from 15.0-20.0 μmol/L group and the number of stenosal cerebral vascular was 66 strips,41 cases (24.70%)came from above 20.1 μmol/L group and the number of stenosal cerebral vascular was 67.Analysis of variance was conducted between the numbers of stenosal cerebral vascular of each group,the differences were significant (F =4.12,P <0.05).Conclusion In cerebral infarction patients,the incidence of Hcy(hyperhomocysteinemia) was higher than that of normal hcy.2.shows more serious damage of intracranial and extracranial arterial sclerosis occur in patients with the increase of homocysteine levels.