Oral squamous cell carcinoma(OSCC)is a malignant lesion originating from the oral mucosal squamous epithelium,account-ing for over 80％of oral and maxillofacial malignancies.Key etiological factors include tobacco,alcohol abuse,and betel quid chewing.In China,its incidence has shown an overall upward trend,posing a significant threat to public health.OSCC exhibits high local invasive-ness,making early diagnosis critical for improving prognosis.Its clinical management requires close multidisciplinary collaboration among oral and maxillofacial surgery,head and neck surgery,radiation oncology,medical oncology,reconstructive surgery,radiology,patholo-gy,and nutritional support teams.Given the increasing disease burden of OSCC and rapid development of multidisciplinary collaborative models,an expert panel has formulated this integrated management consensus based on evidence-based medicine and extensive deliber-ation.Centered on the'Prevention-Screening-Diagnosis-Treatment-Rehabilitation'framework,the consensus provides comprehensive guidance for the entire disease course of OSCC patients,aiming to standardize clinical practice.

Periodontal trauma refers to the pathological damage or abnormal alterations of periodontal tissue caused by a variety of factors, involving a complex physical-chemical-biological coupling mechanism. Its accurate diagnosis, evaluation, and repair are essential for the recovery of oral function and long-term prognosis. The traditional single technique cannot accurately reflect the status of periodontal tissue due to limitations such as incomplete mechanical characterization or missing biological information. Finite element analysis improves the accuracy of physical simulation through the development of a finite element constitutive model, multi-physics coupling, finite element dynamic analysis, and multi-scale modeling. Based on the molecular chemical composition and microenvironment information of periodontal tissue obtained by inelastic light scattering molecular vibration “fingerprinting,” Raman spectroscopy can be used to detect the conformational changes of collagen, mineralization gradient, and inflammatory molecular markers after trauma. Raman spectroscopy can detect microscopic damage earlier than traditional detection methods. The application of finite element analysis or Raman spectroscopy alone can only be used in physical simulation, such as stress-strain analysis or molecular chemical detection of periodontal tissue trauma, and its function is relatively limited. However, the combination of the two modalities combined with AI (artificial intelligence) can analyze the biomechanical mechanism, molecular pathological changes, and dynamic repair process of periodontal tissue trauma, and it has clinical application advantages such as early accurate diagnosis of disease and personalized treatment optimization. The combined application of finite element analysis and Raman spectroscopy in the study of periodontal trauma is still in its infancy; studies have experienced issues with multimodal data fusion, clinical validation, and a lag in real-time feedback. In future work, it will be necessary to combine AI to optimize the efficiency of models, break through disciplinary barriers, and focus on multi-scale data fusion and clinical application, and expand interdisciplinary technology integration. This article focuses on the research progress of finite element analysis, Raman spectroscopy, and their combined multimodal techniques in the application of periodontal tissue trauma, and proposes a type of finite element analysis-Raman spectroscopy multimodal technology supplemented with AI.

Oropharyngeal squamous cell carcinoma(OPSCC)is a malignant tumor originating from the squamous epithelium of the oro-pharyngeal mucosa,accounting for more than 90％of oropharyngeal malignancies.In recent years,human papillomavirus(HPV)infec-tion has become one of the primary etiological factors of oropharyngeal squamous carcinoma.The incidence of HPV-associated oropharyn-geal squamous carcinoma has been rising annually,with a noticeable trend toward younger populations,posing a significant threat to hu-man health.Due to the distinct biological behavior and clinical characteristics of HPV-associated oropharyngeal squamous carcinoma com-pared to its non-HPV-related counterpart,the diagnostic and treatment strategies for oropharyngeal squamous carcinoma have undergone substantial changes.Prevention and screening for oropharyngeal squamous carcinoma are of critical importance.The diagnostic and treat-ment process involves multi-disciplinary collaboration,including oral and maxillofacial surgery,otolaryngology,head and neck surgery,oncology,radiology and pathology.Based on evidence from clinical practice,a comprehensive,integrated diagnostic and therapeutic ap-proach has been established,centered around the concept of"prevention,screening,diagnosis,treatment,and rehabilitation",covering the entire patient lifecycle and providing a valuable reference for clinical practice.

The advancement of surgical techniques enables effective treatment for many patients with oral and maxillofacial tumors.How-ever,post-surgery problems such as chewing,swallowing and speech difficulty may arise due to the defects in speech organs and inade-quate compensatory function of tissue flap repair.Speech disorders,in particular,isolate patients by making it difficult for them to com-municate with others,not only impact their quality of life but also potentially lead to psychological problems and social interaction disor-ders.Although the decline in life quality and other related issues caused by speech dysfunction due to surgery and radiotherapy or chemo-therapy have been widely recognized,there is currently no standardized and universally applicable assessment method and standardized re-habilitation treatment management guideline or consensus for speech disorders following oral and maxillofacial tumor surgery at home and abroad.Based on previous clinical practice,combined with the characteristics of speech disorders in patients after oral and maxillofacial tumor surgery,the clinical experience of the experts in maxillofacial tumor surgery and rehabilitation and the relevant domestic and foreign literature,relevant experts organized discussions and modifications,reach a consensus on core content such as the assessment of speech disorders and the implementation plan for early rehabilitation treatment management,providing a reference for clinical practice,in order to improve patients'speech-related life quality and enhance the assessment and rehabilitation treatment techniques for speech disorders after oral and maxillofacial tumor surgery.

Objective:To measure and analyse maxillofacial skeletal morphology based on the 3D model by Mimics and Matlab soft-ware.Methods:140 male volunteers aged 18-37 years,99 of Han,32 of Uygur and 9 of other natinalities were included.The values of maxillofacial skeletal morphology were measured by Mimics software combined with Matlab software after CT scanning.The data of skeletal morphologic features among skeletal classⅠ,Ⅱ and Ⅲ and among the ethnic groups were analysed with SPSS 26.0 software.Results:The distribution of skeletal class showed that there were 83 cases(59.3％)of class Ⅰ,41(29.3％)of class Ⅱ and 16(11％)of class Ⅲ.There were no significant differences on the age,height,nasal bone length,nasal bone depth,maxillary width,maxillary height,mandibular symphysis height,condylion distance and gonion distance among the 3 skeletal groups(P＞0.05).Skeletal class Ⅱshowed a significant shorter mandibular ramus,mandibular body and entire mandibular length compared with class Ⅰ and class Ⅲ,while class Ⅱ had a significant longer palatal length and larger Me angle compared with class Ⅲ(P＜0.05).Skeletal class Ⅲ showed no significance differences of all dimensions compared with class Ⅰ(P＞0.05).The nasal bone depth of Han subjects was smaller than that of Uygur,while the length of the mandibular symphysis and the entire mandible of Han group were greater than that of Uygur group(P＜0.05).No correlation was observed between age and all facial skeletal dimensions respectively(P＞0.05).The ANB an-gle is negatively correlated with the mandibular body(r=-0.327)and mandibular length(r=-0.322)respectively.Conclusion:There was no significant difference in nasal bone,facial bone width and facial bone height among the 3 skeletal patterns.Class Ⅱhas a significant shorter mandibular ramus,mandibular body and entire mandibular length.Uygur young males have significantly greater nasal bone depth than Han.

Oral squamous cell carcinoma(OSCC)is a malignant lesion originating from the oral mucosal squamous epithelium,account-ing for over 80％of oral and maxillofacial malignancies.Key etiological factors include tobacco,alcohol abuse,and betel quid chewing.In China,its incidence has shown an overall upward trend,posing a significant threat to public health.OSCC exhibits high local invasive-ness,making early diagnosis critical for improving prognosis.Its clinical management requires close multidisciplinary collaboration among oral and maxillofacial surgery,head and neck surgery,radiation oncology,medical oncology,reconstructive surgery,radiology,patholo-gy,and nutritional support teams.Given the increasing disease burden of OSCC and rapid development of multidisciplinary collaborative models,an expert panel has formulated this integrated management consensus based on evidence-based medicine and extensive deliber-ation.Centered on the'Prevention-Screening-Diagnosis-Treatment-Rehabilitation'framework,the consensus provides comprehensive guidance for the entire disease course of OSCC patients,aiming to standardize clinical practice.

Objective:To measure and analyse maxillofacial skeletal morphology based on the 3D model by Mimics and Matlab soft-ware.Methods:140 male volunteers aged 18-37 years,99 of Han,32 of Uygur and 9 of other natinalities were included.The values of maxillofacial skeletal morphology were measured by Mimics software combined with Matlab software after CT scanning.The data of skeletal morphologic features among skeletal classⅠ,Ⅱ and Ⅲ and among the ethnic groups were analysed with SPSS 26.0 software.Results:The distribution of skeletal class showed that there were 83 cases(59.3％)of class Ⅰ,41(29.3％)of class Ⅱ and 16(11％)of class Ⅲ.There were no significant differences on the age,height,nasal bone length,nasal bone depth,maxillary width,maxillary height,mandibular symphysis height,condylion distance and gonion distance among the 3 skeletal groups(P＞0.05).Skeletal class Ⅱshowed a significant shorter mandibular ramus,mandibular body and entire mandibular length compared with class Ⅰ and class Ⅲ,while class Ⅱ had a significant longer palatal length and larger Me angle compared with class Ⅲ(P＜0.05).Skeletal class Ⅲ showed no significance differences of all dimensions compared with class Ⅰ(P＞0.05).The nasal bone depth of Han subjects was smaller than that of Uygur,while the length of the mandibular symphysis and the entire mandible of Han group were greater than that of Uygur group(P＜0.05).No correlation was observed between age and all facial skeletal dimensions respectively(P＞0.05).The ANB an-gle is negatively correlated with the mandibular body(r=-0.327)and mandibular length(r=-0.322)respectively.Conclusion:There was no significant difference in nasal bone,facial bone width and facial bone height among the 3 skeletal patterns.Class Ⅱhas a significant shorter mandibular ramus,mandibular body and entire mandibular length.Uygur young males have significantly greater nasal bone depth than Han.

Oropharyngeal squamous cell carcinoma(OPSCC)is a malignant tumor originating from the squamous epithelium of the oro-pharyngeal mucosa,accounting for more than 90％of oropharyngeal malignancies.In recent years,human papillomavirus(HPV)infec-tion has become one of the primary etiological factors of oropharyngeal squamous carcinoma.The incidence of HPV-associated oropharyn-geal squamous carcinoma has been rising annually,with a noticeable trend toward younger populations,posing a significant threat to hu-man health.Due to the distinct biological behavior and clinical characteristics of HPV-associated oropharyngeal squamous carcinoma com-pared to its non-HPV-related counterpart,the diagnostic and treatment strategies for oropharyngeal squamous carcinoma have undergone substantial changes.Prevention and screening for oropharyngeal squamous carcinoma are of critical importance.The diagnostic and treat-ment process involves multi-disciplinary collaboration,including oral and maxillofacial surgery,otolaryngology,head and neck surgery,oncology,radiology and pathology.Based on evidence from clinical practice,a comprehensive,integrated diagnostic and therapeutic ap-proach has been established,centered around the concept of"prevention,screening,diagnosis,treatment,and rehabilitation",covering the entire patient lifecycle and providing a valuable reference for clinical practice.

The advancement of surgical techniques enables effective treatment for many patients with oral and maxillofacial tumors.How-ever,post-surgery problems such as chewing,swallowing and speech difficulty may arise due to the defects in speech organs and inade-quate compensatory function of tissue flap repair.Speech disorders,in particular,isolate patients by making it difficult for them to com-municate with others,not only impact their quality of life but also potentially lead to psychological problems and social interaction disor-ders.Although the decline in life quality and other related issues caused by speech dysfunction due to surgery and radiotherapy or chemo-therapy have been widely recognized,there is currently no standardized and universally applicable assessment method and standardized re-habilitation treatment management guideline or consensus for speech disorders following oral and maxillofacial tumor surgery at home and abroad.Based on previous clinical practice,combined with the characteristics of speech disorders in patients after oral and maxillofacial tumor surgery,the clinical experience of the experts in maxillofacial tumor surgery and rehabilitation and the relevant domestic and foreign literature,relevant experts organized discussions and modifications,reach a consensus on core content such as the assessment of speech disorders and the implementation plan for early rehabilitation treatment management,providing a reference for clinical practice,in order to improve patients'speech-related life quality and enhance the assessment and rehabilitation treatment techniques for speech disorders after oral and maxillofacial tumor surgery.

Oral and maxillofacial malignant tumors threaten the life and health of patients, and seriously affect their swallowing, language function and face. 125I seeds brachytherapy for oral and maxillofacial malignant tumors has been widely concerned and studied because of its advantages such as less surgical trauma, large and uniform dose distribution in the target tissue, little damage to the surrounding normal tissue, and reducing radiation exposure of medical staff. Low-dose brachytherapy with 125I seeds can effectively reduce the tumor volume and prolong the survival time of patients. This article reviews the clinical application of 125I seeds brachytherapy in oral and maxillofacial malignant tumors.