1.Two cases of unicornuate uterus with ectopic ovary in IVF-ET and literature review
Yaqin WANG ; Qianrong QI ; Wangming XU ; Xiaoyan ZHOU ; Jing YANG
Chinese Journal of Reproduction and Contraception 2022;42(6):621-625
Objective:To summarize the management of unicornuate uterus with ectopic ovary during in vitro fertilization and embryo transfer (IVF-ET). Methods:The clinical data of 2 rare cases of uniangular uterus with ectopic ovary undergoing IVF-ET were retrospectively analyzed and the related literatures were reviewed.Results:Two patients were diagnosed as unicornuate uterus with unilateral ovary missing by vaginal ultrasound, subsequent abdominal ultrasound and magnetic resonance imaging (MRI) results indicated follicular structure in the peritoneal area, suggesting ectopic ovary. Case 1 showed flank pain as well as discrepancy between serum estradiol level and follicle numbers during ovarian hyperstimulation. The patient received trans-abdominal combined with trans-vaginal oocyte retrieval and successfully delivered a healthy baby at 36 weeks by transferring frozen blastocyst embryo. Case 2 was diagnosed as unicornuate uterus with lateral ectopic ovary by abdominal ultrasound before IVF treatment. We performed synchronized monitoring of bilateral ovarian follicular development and oocytes retrieval by transabdominal and transvaginal ultrasound, and then the two blastocysts were cryopreserved. However, the patient experienced spontaneous abortion following single frozen-thawed blastocyst transfer.Conclusion:Ectopic ovaries present no obvious clinical manifestation and is easy to be ignored in diagnosis. For patients with unicornuate uterus treated by assisted reproductive technology, if vaginal ultrasound fails to detect ovary, we should further perform abdominal ultrasound or MRI to screen for ectopic ovary. If diagnosed with ectopic ovary, the patients should simultaneously be monitored the follicullar development of bilateral ovaries during the process of ovarian hyperstimulation and adopt both transabdominal and transvaginal ultrasound-guided follicular aspiration to maximize the numbers of oocyte and pregnancy chance.
2.Two cases of unicornuate uterus with ectopic ovary in IVF-ET and literature review
Yaqin WANG ; Qianrong QI ; Wangming XU ; Xiaoyan ZHOU ; Jing YANG
Chinese Journal of Reproduction and Contraception 2022;42(6):621-625
Objective:To summarize the management of unicornuate uterus with ectopic ovary during in vitro fertilization and embryo transfer (IVF-ET). Methods:The clinical data of 2 rare cases of uniangular uterus with ectopic ovary undergoing IVF-ET were retrospectively analyzed and the related literatures were reviewed.Results:Two patients were diagnosed as unicornuate uterus with unilateral ovary missing by vaginal ultrasound, subsequent abdominal ultrasound and magnetic resonance imaging (MRI) results indicated follicular structure in the peritoneal area, suggesting ectopic ovary. Case 1 showed flank pain as well as discrepancy between serum estradiol level and follicle numbers during ovarian hyperstimulation. The patient received trans-abdominal combined with trans-vaginal oocyte retrieval and successfully delivered a healthy baby at 36 weeks by transferring frozen blastocyst embryo. Case 2 was diagnosed as unicornuate uterus with lateral ectopic ovary by abdominal ultrasound before IVF treatment. We performed synchronized monitoring of bilateral ovarian follicular development and oocytes retrieval by transabdominal and transvaginal ultrasound, and then the two blastocysts were cryopreserved. However, the patient experienced spontaneous abortion following single frozen-thawed blastocyst transfer.Conclusion:Ectopic ovaries present no obvious clinical manifestation and is easy to be ignored in diagnosis. For patients with unicornuate uterus treated by assisted reproductive technology, if vaginal ultrasound fails to detect ovary, we should further perform abdominal ultrasound or MRI to screen for ectopic ovary. If diagnosed with ectopic ovary, the patients should simultaneously be monitored the follicullar development of bilateral ovaries during the process of ovarian hyperstimulation and adopt both transabdominal and transvaginal ultrasound-guided follicular aspiration to maximize the numbers of oocyte and pregnancy chance.
3.Expert consensus on intensive care ultrasound
Lan CAO ; Lina ZHANG ; Xiaoting WANG ; Xin LI ; Qing ZHANG ; Jianhua SUN ; Meishan LU ; Na GUO ; Dun TIAN ; Yang SUN ; Tingting ZHANG ; Qianrong DING ; Qi LIU ; Weiqing ZHANG
Chinese Journal of Modern Nursing 2020;26(33):4577-4590
With the development of critical care ultrasound technology, clinics begins to pay attention to the role of critical care ultrasound in nursing of critically ill patients. The increasingly extensive application of ultrasound in the field of critical care provides a visual tool for clinical nursing work, which can qualitatively and quantitatively evaluate nursing indicators, help to solve the existing nursing problems and nursing difficulties and promote the improvement of critical care quality and the development of nursing academics. To this end, experts formulates this consensus based on years of experience and application of intensive care ultrasound practice.
4.Clinical Observation of Triptorelin Acetate in the Treatment of Endometriosis after Laparoscopy
Min WU ; Qianrong QI ; Yujie ZOU
China Pharmacy 2016;27(8):1094-1095,1096
OBJECTIVE:To observe clinical efficacy and safety of triptorelin acetate in the treatment of endometriosis after lap-aroscopy. METHODS:196 cases of endometriosis were randomly divided into experimental group and control group with 98 cases in each group according to admission sequence. Both groups received laparoscopic surgery. After surgery,experimental group was given triptorelin acetate by intramuscular injection,3.75 mg/time,every 4 weeks;control group was given gestrinone orally,2.5 mg/time,twice a week,for 5 months. The ovulation,menstrual recovery and the occurrence of ADR were observed in 2 groups. The endometriosis relapse of 2 groups were followed up for 1 year and observed. RESULTS:After treatment,the ovulation recov-ery time and menstrual recovery time of experimental group were all shorter than those of control group,with statistical signifi-cance(P<0.05). The incidence of ADR in experimental group(17.34%)was significantly lower than in control group(35.71%), with statistical significance(P<0.05). During follow-up period,the relapse rate of experimental group(7.14%)was significantly lower than that of control group(18.37%),with statistical significance(P<0.05). CONCLUSIONS:After laparoscopic surgery, triptorelin acetate can significantly improve therapeutic efficacy of endometriosis,reduce the occurrence of ADR.

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