Objective To investigate the influence of metabolic associated fatty liver disease(MAFLD)on the severity of acute pan-creatitis(AP)by exploring the relationship between them.Methods The clinical data of 526 AP patients who were admitted to the Affil-iated Hospital of Xuzhou Medical University from January 2021 to March 2023 were retrospectively analyzed.The severity of AP was as-sessed by the revised Atlanta classification,bedside index for severity in acute pancreatitis(BISAP)score,and modified CT severity in-dex(MCTSI)score.The patients were divided into MAFLD group(n=294)and non-MAFLD group(n=232)according to the pres-ence or absence of MAFLD.The two groups were compared in terms of the the indices such as general data,laboratory indicators,severi-ty,complications,the length of hospital stay.Univariate and multivariate Logistic regression analysis were also used to screen the inde-pendent risk factors for the severity of AP.Results The incidence of moderately severe acute pancreatitis(MSAP)and severe acute pan-creatitis(SAP)in MAFLD group were higher than those in non-MAFLD group,the BISAP score,MCTSI score,the incidence of local and systemic complications and.the duration of hospitalization and hospital stay in ICU for patients in MAFLD were also higher than those in non-MAFLD.Multivariable Logistic regression analysis showed that MAFLD was an independent risk factor for MSAP and SAP.Conclusion MAFLD increases the risk of AP.The presence of MAFLD portends a higher risk of MSAP and SAP,as well as higher inci-dence of local and systemic complications.

Objective To investigate the influence of metabolic associated fatty liver disease(MAFLD)on the severity of acute pan-creatitis(AP)by exploring the relationship between them.Methods The clinical data of 526 AP patients who were admitted to the Affil-iated Hospital of Xuzhou Medical University from January 2021 to March 2023 were retrospectively analyzed.The severity of AP was as-sessed by the revised Atlanta classification,bedside index for severity in acute pancreatitis(BISAP)score,and modified CT severity in-dex(MCTSI)score.The patients were divided into MAFLD group(n=294)and non-MAFLD group(n=232)according to the pres-ence or absence of MAFLD.The two groups were compared in terms of the the indices such as general data,laboratory indicators,severi-ty,complications,the length of hospital stay.Univariate and multivariate Logistic regression analysis were also used to screen the inde-pendent risk factors for the severity of AP.Results The incidence of moderately severe acute pancreatitis(MSAP)and severe acute pan-creatitis(SAP)in MAFLD group were higher than those in non-MAFLD group,the BISAP score,MCTSI score,the incidence of local and systemic complications and.the duration of hospitalization and hospital stay in ICU for patients in MAFLD were also higher than those in non-MAFLD.Multivariable Logistic regression analysis showed that MAFLD was an independent risk factor for MSAP and SAP.Conclusion MAFLD increases the risk of AP.The presence of MAFLD portends a higher risk of MSAP and SAP,as well as higher inci-dence of local and systemic complications.

Large vessel occlusion (LVO) is a common vascular event in acute ischemic stroke. It is recommended to carry out endovascular therapy as soon as possible to save ischemic penumbra. Thus it is of great importance to identify the pre-hospital patients with LVO. At present, there are many LVO screening tools for prehospital settings, such as Los Angeles Motor Scale, Cincinnati Prehospital Stroke Severity Scale, the Rapid Arterial oCclusion Evaluation scale and so on. We will review the research advances on LVO screening tools to improve the clinical work.