1.Double profunda femoris artery: a unique anatomical variation with surgical significance
Punnapa RAVITEJA ; Mrudula CHANDRUPATLA ; Alka Vithalrao BHINGARDEO
Anatomy & Cell Biology 2026;59(1):193-197
The profunda femoris artery (PFA) originates from the femoral artery, supplying crucial blood flow to thigh muscles, hip joint, and femur. We report a rare unilateral anatomical variation involving an accessory profunda femoris artery (APFA) originating 0.5 cm from the mid-inguinal point (MIP) and a main PFA arising 3.6 cm from the MIP. The APFA supplies the pectineus, adductor longus, and adductor magnus muscles, and gives off the superficial circumflex iliac artery. The main PFA gives rise to circumflex and perforating branches. This variation highlights the complexity of human anatomy and has significant clinical implications, particularly in vascular surgery, plastic surgery, and interventional radiology. Understanding anatomical variations, such as dual PFAs, is crucial for preventing complications during vascular procedures like catheterization and SCIP flap reconstruction. Preoperative assessment and intraoperative adaptability are essential to mitigate risks of arterial injury, dissection, or inadequate perfusion.
2.A rare anatomical variation of the deep femoral vein with aneurysm: a case report with clinical significance
Punnapa RAVITEJA ; Mrudula CHANDRUPATLA ; Rohini MOTWANI ; Saravana Kumar MG
Anatomy & Cell Biology 2026;59(1):198-201
We present a rare anatomical variation of the deep femoral vein (DFV) originating from the popliteal vein (PV) with an associated aneurysm. The DFV arose from the PV at the adductor hiatus, exhibited an aneurysm, and coursed upward through the fourth osseo-aponeurotic opening of the adductor magnus muscle to enter the anterior thigh compartment before draining into the femoral vein. This unique variation likely resulted from developmental deviations during intrauterine life. The anomalous origin and aneurysm of the DFV may potentially cause venous hemodynamic disturbances, chronic venous insufficiency, increased risk of deep vein thrombosis, and potentially life-threatening pulmonary embolism. Anatomical variations of the DFV in terms of origin, course, or termination are rare but clinically relevant, especially in the context of vascular surgeries, imaging, and interventional procedures involving the femoral region.This case highlights the importance of recognizing venous anatomical variations and their clinical implications.
3.Cadaveric revelation of medial cutaneous nerve of the arm traversing the axillary vein
Punnapa RAVITEJA ; Mrudula CHANDRUPATLA ; Rohini MOTWANI
Anatomy & Cell Biology 2025;58(4):638-641
A rare unilateral anatomical variation was observed in the left arm of a 62-year-old female cadaver. The medial cutaneous nerve of the arm pierced the axillary vein, arising from the medial cord of the brachial plexus and coursing posterior to the axillary artery. The nerve traversed the vein over a short segment, entering at approximately 6.5 cm and exiting at approximately 7.5 cm from the coracoid process. This unusual relationship has significant clinical implications in medical procedures, particularly in axillary venous access. Failure to recognize these alterations during axillary lymph node dissections or brachial plexus procedures increases the probability of iatrogenic nerve damage or venous trauma. This case highlights the importance of preoperative imaging and vigilant dissection techniques to accommodate anatomical variability, ultimately enhancing procedural safety and patient outcomes. Recognizing such variations is crucial to prevent sensory deficits, chronic neuropathic pain, and other complications.
4.Tri-ramification of left external carotid artery associated with anatomical variation of its branches and aneurysm formation
Punnapa RAVITEJA ; Mrudula CHANDRUPATLA ; Rohini MOTWANI
Anatomy & Cell Biology 2024;57(2):324-327
Essential sources of arterial vascularisation in the head and neck region are the left and right common carotid arteries (CCA) and their branches. The left CCA (LCCA) originates from the arch of the aorta and the right CCA originates from the brachiocephalic trunk. In this case report, there was a bilateral higher division of CCA at the plane of the greater cornua of the hyoid bone, unilateral tri-ramification of the LCCA and the left external carotid artery (LECA), and the origin of the linguo-facial trunk and the pharyngo-occipital trunk from the LECA. An aneurysm formed in the distal part of LECA before its termination. In this case, we propose a novel categorization called the punnapatla classification for the anatomical variance branching forms of ECA. These kinds of variations are important to the surgeons, and anaesthetists, during the surgeries of the head and neck.

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