2.Analysis of the transcripts encoding for antigenic proteins of bovine gammaherpesvirus 4
Florencia ROMEO ; Maximiliano J SPETTER ; Pedro MORAN ; Susana PEREYRA ; Anselmo ODEON ; Sandra E PEREZ ; Andrea E VERNA
Journal of Veterinary Science 2020;21(1):5-
coding for the envelope glycoproteins occurred earlier in cells infected with isolate 10/154 than in cells infected with strain 07/435, demonstrating a distinct difference between the strains. Differences in serological response can be attributed to differences in the expression of antigenic proteins or to post-translational modifications that mask neutralizing epitopes. Strain 07/435 induced significantly high titers of neutralizing antibodies in several animal species in addition to bovines. The most relevant serological differences were observed in adult animals. This is the first comprehensive analysis of the expression kinetics of genes coding for BoHV-4 glycoproteins in 2 Argentine strains (genotypes 1 and 2). The results further elucidate the BoHV-4 life cycle and may also help determine the genetic variability of the strains circulating in Argentina.]]>
Adult
;
Animals
;
Antibodies
;
Antibodies, Neutralizing
;
Argentina
;
Cattle
;
Clinical Coding
;
Epitopes
;
Glycoproteins
;
Glycosylation
;
Humans
;
In Vitro Techniques
;
Kinetics
;
Life Cycle Stages
;
Masks
;
Protein Processing, Post-Translational
;
Transcriptome
;
Virion
3.Anaphylaxis diagnosis and management in the Emergency Department of a tertiary hospital in the Philippines
Michelle Joy DE VERA ; Iris Conela TAGARO
Asia Pacific Allergy 2020;10(1):1-
BACKGROUND: In the Emergency Department (ED), diagnosis and management of anaphylaxis are challenging with at least 50% of anaphylaxis episodes misdiagnosed when the diagnostic criteria of current guidelines are not used.OBJECTIVE: Objective of our study was to assess anaphylaxis diagnosis and management in patients presenting to the ED.METHODS: Retrospective chart review conducted on patients presenting to The Medical City Hospital ED, the Philippines from 2013–2015 was done. Cases were identified based on International Statistical Classification of Diseases, 10th revision coding for either anaphylaxis or other allergic related diagnosis. Cases fitting the definition of anaphylaxis as identified by the National Institute of Allergy and Infectious Disease and the Food Allergy and Anaphylaxis Network (NIAID/FAAN) were included. Data collected included demographics, signs and symptoms, triggers and management.RESULTS: A total of 105 cases were evaluated. Incidence of anaphylaxis for the 3-year study period was 0.03%. Of the 105 cases, 35 (33%) were diagnosed as “urticaria” or “hypersensitivity reaction” despite fulfilling the NIAID/FAAN anaphylaxis criteria. There was a significant difference in epinephrine administration between those given the diagnosis of anaphylaxis versus misdiagnosed cases (61 [87%] vs. 12 [34%], χ² = 30.77, p < 0.01); and a significant difference in time interval from arrival at the ED to epinephrine administration, with those diagnosed as anaphylaxis (48%) receiving epinephrine within 10 minutes, versus ≥ 60 minutes for most of the misdiagnosed group (χ² = 52.97, p < 0.01).CONCLUSION: Despite current guidelines, anaphylaxis is still misdiagnosed in the ED. Having an ED diagnosis of anaphylaxis significantly increases the likelihood of epinephrine administration, and at a shorter time interval.
Anaphylaxis
;
Classification
;
Clinical Coding
;
Communicable Diseases
;
Demography
;
Diagnosis
;
Emergencies
;
Emergency Service, Hospital
;
Epinephrine
;
Food Hypersensitivity
;
Hospitals, Urban
;
Humans
;
Hypersensitivity
;
Incidence
;
Philippines
;
Retrospective Studies
;
Tertiary Care Centers
4.Current situation and demands for diabetes knowledge in prediabetes patients at different self-management levels.
Hui ZENG ; Pingping YAN ; Guanxiu TANG ; Qian LIU ; Feifen LIU ; Hongmei ZHOU ; Miaojuan XIA
Journal of Central South University(Medical Sciences) 2019;44(6):679-684
To understand the current situation regarding the knowledge and demand for patients with prediabetes at different self-management levels, and to provide guide for improving their knowledge.
Methods: A total of 312 prediabetes patients from 3 hospitals in Changsha were enrolled in this survey. The questionnaires covered diabetes self-management behavior scale and prediabetes knowledge status and demand questionnaire. Diabetes knowledge acquisition and demand were analyzed among patients with different levels of self-management.
Results: The score of self-management behavior for patients with prediabetes was 39.1±13.9. The rate of knowledge acquisition was low and the rate of demand was high. The knowledge acquisition rate was high and the knowledge demand rate was low in patients with high levels of self-management. As for the contents of health education, the dietary collocation and method for glucose detection were highly needed by all self-management levels of patients.
Conclusion: Prediabetes patients' self-management level are low. Health education to patients with prediabetes should be based on individualized demands.
Diabetes Mellitus
;
Health Knowledge, Attitudes, Practice
;
Humans
;
Prediabetic State
;
Self-Management
;
Surveys and Questionnaires
6.Effects Of Inappropriate Waste Management On Health: Knowledge, Attitude And Practice Among Malaysian Population
Redhwan Ahmed Al-Naggar ; Mahfoudh A.M Abdulghani ; Mahmoud Abdullah Al-Areefi
Malaysian Journal of Public Health Medicine 2019;19(1):101-109
Numerous health issues can arise from improper domestic waste management. Uncollected wastes provide food and breeding sites for insect, bird and rodent which can expose the community to vector borne disease. Therefore, this study aims to investigate the community awareness towards domestic waste management. This study is a cross-sectional study conducted at Bandar Baru Sungai Buloh, Selangor, Malaysia. The questionnaire consists of five sections with a total of 57 questions. The questionnaire consists of four parts: Socio-demographic, knowledge, attitude and practice. The data were analysed using SPSS version 22.0. T-test, ANOVA test, Chi-squared test were used according to the type of variables and significance level will be taken at 95% or p-value of less than 0.05. A total of 355 respondents participated in this study. The mean age was 40.52 ±14.94. The majority of them were male (52.1%), Malay (71.0%), married (71.3%), with secondary educational (81%) and employed (41.1%). The majority of respondents mentioned that inappropriate waste management can cause dengue fever and leptospirosis (98.0%, 97.2%; respectively). Property type, education, occupation, ethnicity, religions and household income were significant influenced the knowledge of the participants towards domestic waste management. For attitude, gender, education, ethnicity, religion and income significantly influenced the attitude of the participants towards domestic waste management. For practice, ethnicity, religion and occupation were significantly influenced the practice of the participants towards domestic waste management. In conclusion, the community has moderate awareness of domestic waste management. Awareness of waste management should also be taught in school so that the next generation of people will have a better understanding and eventually have better practice in domestic waste management. It is also hoped that a carefully thought-out strategy can be developed to further improve the community awareness towards domestic waste management which will shed a new light on tackling this issue.
Waste Management
;
Health
;
Knowledge
;
Attitude
;
Practice
;
general population
7.Computer-based clinical coding activity analysis for neurosurgical terms
Jong Hyuk LEE ; Jung Hwan LEE ; Wooseok RYU ; Byung Kwan CHOI ; In Ho HAN ; Chang Min LEE
Yeungnam University Journal of Medicine 2019;36(3):225-230
BACKGROUND: It is not possible to measure how much activity is required to understand and code a medical data. We introduce an assessment method in clinical coding, and applied this method to neurosurgical terms.METHODS: Coding activity consists of two stages. At first, the coders need to understand a presented medical term (informational activity). The second coding stage is about a navigating terminology browser to find a code that matches the concept (code-matching activity). Systematized Nomenclature of Medicine – Clinical Terms (SNOMED CT) was used for the coding system. A new computer application to record the trajectory of the computer mouse and record the usage time was programmed. Using this application, we measured the time that was spent. A senior neurosurgeon who has studied SNOMED CT has analyzed the accuracy of the input coding. This method was tested by five neurosurgical residents (NSRs) and five medical record administrators (MRAs), and 20 neurosurgical terms were used.RESULTS: The mean accuracy of the NSR group was 89.33%, and the mean accuracy of the MRA group was 80% (p=0.024). The mean duration for total coding of the NSR group was 158.47 seconds, and the mean duration for total coding of the MRA group was 271.75 seconds (p=0.003).CONCLUSION: We proposed a method to analyze the clinical coding process. Through this method, it was possible to accurately calculate the time required for the coding. In neurosurgical terms, NSRs had shorter time to complete the coding and higher accuracy than MRAs.
Animals
;
Clinical Coding
;
Humans
;
Medical Informatics
;
Medical Record Administrators
;
Methods
;
Mice
;
Neurosurgeons
;
Systematized Nomenclature of Medicine
8.Steatocystoma multiplex: A case report of a rare entity
Nan Young SHIN ; Ju Hee KANG ; Jo Eun KIM ; Khantaly SYMKHAMPA ; Kyung Hoe HUH ; Won Jin YI ; Min Suk HEO ; Sam Sun LEE ; Soon Chul CHOI
Imaging Science in Dentistry 2019;49(4):317-321
Steatocystoma multiplex is an uncommon benign skin disease, which typically manifests as numerous intradermal cysts that can be scattered anywhere on the body. Although usually asymptomatic, it can be significantly disfiguring. One type of steatocystoma multiplex is known to be associated with the autosomal dominant inheritance of a mutation in the gene coding for keratin 17 (KRT17). In such cases, it is often concurrent with other developmental abnormalities of the ectoderm-derived tissues, such as the nails, hair, and teeth. To the best of our knowledge, few cases have been reported of steatocystoma multiplex of the oral and maxillofacial region. This report describes a case of steatocystoma multiplex of both sides of the neck and multiple dental anomalies, with a focus on its clinical, radiological, and histopathological characteristics, as well as the possibility that the patient exhibited the familial type of this condition.
Clinical Coding
;
Hair
;
Humans
;
Keratin-17
;
Neck
;
Skin Diseases
;
Steatocystoma Multiplex
;
Tooth
;
Wills
9.Factors Influencing Intentional Rounding Performance of Tertiary General Hospital Nurses
Journal of Korean Academy of Nursing Administration 2019;25(5):437-447
PURPOSE: The purpose of this study was to examine the effects of perceptions of patient rounding, self-leadership and nursing organization culture on intentional rounding performance.METHODS: The participants for this study were 210 nurses who had the experience of patient rounding care in general hospitals in B and Y cities. Data were collected from February 5th to 22nd, 2018. Collected data were analyzed using descriptive statistics, χ² test, and independent t-test. Logistic regression analysis was performed to identify factors influencing intentional rounding performance.RESULTS: It was found that intentional rounding performance was carried out by 20.0% of the day shift nurses, 18.1% of the evening shift nurses, and 19.5% of the night shift nurses. The significant factors influencing intentional rounding performance were the recommended rounding time interval in wards and the use of rounding protocol in the wards (p < .050).CONCLUSION: It is expected that nurses will be able to provide more advanced and efficient patient rounding by promising a systematic patient rounding time for intentional rounding and developing appropriate protocols for each ward.
Hospitals, General
;
Humans
;
Logistic Models
;
Nursing
;
Practice Management
;
Teaching Rounds
10.Adaptation to Motherhood in Central Asian-Korean Immigrants to Korea: A Grounded Theory Study
Su Hyun KIM ; Hyang In CHO CHUNG
Journal of Korean Academy of Nursing 2019;49(6):677-689
PURPOSE: This qualitative study aimed to develop a substantive theory of the process of adaptation to motherhood in Central Asian-Korean immigrants to Korea.METHODS: Individual, in-depth interviews were conducted from July to September 2017, with 18 women who emigrated of Korean ethnicity from Central Asia to Korea, and took care of their baby for at least a year after their first delivery in Korea. The interviews were audio-recorded and transcribed verbatim. Data from the transcriptions were analyzed through Strauss and Corbin's grounded theory method, and data analysis was conducted simultaneously with data collection.RESULTS: As a result of categorizing the interview data through the process of open coding, 10 categories, with 31 subcategories and 102 concepts were drawn, and “growth as a Central Asian-Korean mother in an unfamiliar, historical hometown” was found to be the core category of the process of adaptation to motherhood in Central Asian-Korean immigrants to Korea.CONCLUSION: A characteristic of the process of adaptation to motherhood in Central Asian-Korean immigrants to Korea, drawn from this study, is that it differs according to the level of initiative to carry out interaction strategies, and the use of various supportive social resources. The findings indicate the need for Medicare eligibility adjustment for antenatal care, the extension of the visa renewal period during childbirth, the development of web- or mobile application-based educational programs in Russian language, and the establishment of integrated visiting healthcare services, community service resources, and policy support to enable these women to utilize various supportive social resources.
Adaptation, Psychological
;
Asia
;
Clinical Coding
;
Data Collection
;
Delivery of Health Care
;
Emigrants and Immigrants
;
Female
;
Grounded Theory
;
Humans
;
Korea
;
Medicare
;
Methods
;
Mothers
;
Parturition
;
Qualitative Research
;
Social Welfare
;
Statistics as Topic


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