1.Development and validation of a predictive model for acute respiratory distress syndrome in geriatric patients following gastrointestinal perforation surgery.
Ze ZHANG ; You FU ; Jing YUAN ; Quansheng DU
Chinese Critical Care Medicine 2025;37(8):749-754
OBJECTIVE:
To identify the risk factors for acute respiratory distress syndrome (ARDS) in geriatric patients following gastrointestinal perforation surgery, and constructed a model to validate its predictive value.
METHODS:
A retrospective analysis was conducted. The clinical data of geriatric patients (aged ≥ 60 years) after gastrointestinal perforation surgery admitted to the intensive care unit (ICU) of Hebei General Hospital from October 2017 to October 2024 were enrolled. Two groups were divided according to whether ARDS occurred postoperatively, and the differences in each index between the groups were compared. Lasso regression and multifactorial Logistic regression analyses were used to identify independent risk factors for the development of ARDS, and a prediction model was constructed based on these, which was presented using a nomogram. The receiver operator characteristic curve (ROC curve), calibration curve, and decision curve analysis (DCA) were plotted to evaluate the discrimination, accuracy, and clinical practicability of the model.
RESULTS:
A total of 155 geriatric patients following gastrointestinal perforation surgery were ultimately included in the analysis, among whom 43 developed ARDS, with an incidence rate of 27.7%. There were significantly differences in age, body mass index (BMI), acute kidney injury comorbidity, heart rate, onset time, the duration of surgery, the site of perforation, seroperitoneum, amount of bleeding, shock comorbidity, central venous pressure (CVP), C-reactive protein, and albumin between ARDS and non-ARDS groups. Lasso regression identified nine significant predictors: age, BMI, acute kidney injury comorbidity, onset time, seroperitoneum, shock comorbidity, CVP, hemoglobin, and albumin. Multivariate Logistic regression analysis identified BMI [odds ratio (OR) = 1.310, P < 0.001], hemoglobin (OR = 1.019, P = 0.045), seroperitoneum (OR = 1.001, P = 0.017), and albumin (OR = 0.871, P < 0.001) as independent risk factors for the occurrence of ARDS. A prediction model was constructed based on the above four independent risk factors, and the ROC curve showed that the area under the curve (AUC) of the model for predicting the occurrence of ARDS was 0.885 [95% confidence interval (95%CI) was 0.824-0.946], and internal validation was performed using bootstrap resampling (Bootstrap 500 times), which showed that the AUC value of the model was 0.886 (95%CI was 0.883-0.889). Calibration curves revealed excellent concordance between observed outcomes and model predictions. DCA indicated a high net benefit value for the model, which has good clinical utility.
CONCLUSIONS
BMI, hemoglobin, seroperitoneum, and albumin were identified as independent risk factors for ARDS in geriatric patients following gastrointestinal perforation surgery. The prediction model constructed using these four indicators facilitates early identification of high-risk individuals by clinicians.
Humans
;
Respiratory Distress Syndrome/etiology*
;
Retrospective Studies
;
Aged
;
Risk Factors
;
Logistic Models
;
Postoperative Complications
;
Intestinal Perforation/surgery*
;
Male
;
ROC Curve
;
Female
;
Middle Aged
;
Intensive Care Units
;
Nomograms
2.Conservative treatment of pathological fracture after multiple odontogenic keratocyst surgery: a case report and literature analysis.
Chen XU ; Hongguang CHANG ; Qiang SHAO ; Yonghai SONG
West China Journal of Stomatology 2025;43(1):144-150
Pathological fractures after jaw cyst surgery are rare clinically but are a serious complication. Once a pathological fracture occurs, treatment time and economic costs increase, and doctors face difficulty in handling it. This article reports a case of a patient with mandibular pathological fractures after multiple odontogenic keratocyst surgery of the jaw. Mandibular lesions were located in the bilateral mandibular angles and had macrocystic changes. We adopted a conservative treatment plan, and the treatment effect was good. We also discussed and analyzed relevant literature to provide a reference for clinicians.
Humans
;
Odontogenic Cysts/surgery*
;
Conservative Treatment
;
Postoperative Complications/therapy*
;
Mandibular Fractures/etiology*
;
Fractures, Spontaneous/etiology*
;
Male
;
Female
3.Management of accidental tooth root displacement into the mandibular canal during tooth extraction.
West China Journal of Stomatology 2025;43(6):789-796
The accidental displacement of tooth roots into the mandibular canal is a serious complication during tooth extractions in oral and maxillofacial surgery, often resulting in direct damage to the structural and functional integrity of the inferior alveolar neurovascular bundle (IANB). This article reviews the anatomical features of the mandibular canal, the IANB, and adjacent tooth roots; identifies high-risk factors and anatomically vulnerable sites for root displacement; and outlines the clinical manifestations and radiographic characteristics of intraoperative root intrusion into the mandibular canal. Furthermore, management principles, surgical approaches and techniques, inferior alveolar nerve injury treatment, and prognostic considerations are discussed. The aim of this review is to provide a comprehensive clinical reference for improving surgical outcomes, and reducing postoperative complications.
Humans
;
Tooth Extraction/adverse effects*
;
Mandible/surgery*
;
Tooth Root
;
Mandibular Nerve/anatomy & histology*
;
Postoperative Complications/prevention & control*
;
Intraoperative Complications
;
Mandibular Nerve Injuries/etiology*
4.Construction of risk prediction models of hypothermia after transurethral holmium laser enucleation of the prostate based on three machine learning algorithms.
Jun JIANG ; Shuo FENG ; Yingui SUN ; Yan AN
Journal of Southern Medical University 2025;45(9):2019-2025
OBJECTIVES:
To develop risk prediction models for postoperative hypothermia after transurethral holmium laser enucleation of the prostate (HoLEP) using machine learning algorithms.
METHODS:
We retrospectively analyzed the clinical data of 403 patients from our center (283 patients in the training set and 120in the internal validation set) and 120 patients from Weifang People's Hospital (as the external validation set). The risk prediction models were built using logistic regression, decision tree and support vector machine (SVM), and model performance was evaluated in terms of accuracy, recall, precision, F1 score and AUC.
RESULTS:
Operation duration, prostate weight, intraoperative irrigation volume, and being underweight were identified as the predictors of postoperative hypothermia following HoLEP. Among the 3 algorithms, SVM showed the best precision rate and accuracy in all the 3 data sets and the best area under the ROC (AUC) in the training set and validation set, followed by logistic regression, which had a similar AUC in the two data sets. SVM outperformed logistic regression and decision tree models in the validation set in precision, accuracy, recall, F1 score, and AUC, and performed well in the external validation set with better precision rate and accuracy than logistic regression and decision tree models but slightly lower recall rate, F1 index, and AUC value than the decision tree model. SVM outperformed logistic regression and decision tree models in precision, accuracy, F1 score, and AUC in the training set, but had slightly lower recall rate than the decision tree.
CONCLUSIONS
Among the 3 models, SVM has the best performance and generalizability for predicting post-HoLEP hypothermia risk to provide support for clinical decisions.
Humans
;
Male
;
Retrospective Studies
;
Machine Learning
;
Transurethral Resection of Prostate/adverse effects*
;
Hypothermia/etiology*
;
Prostatic Hyperplasia/surgery*
;
Algorithms
;
Lasers, Solid-State
;
Risk Assessment
;
Postoperative Complications
;
Decision Trees
;
Logistic Models
;
Aged
;
Middle Aged
;
Support Vector Machine
5.Expert consensus on the protection of pelvic organ function in rectal cancer surgery (version 2025).
Chinese Journal of Gastrointestinal Surgery 2025;28(6):575-586
With the development of surgical techniques, adjuvant therapy and neoadjuvant therapy, the survival time of rectal cancer patients after surgery has been significantly improved, but organ dysfunction is still an important problem affecting the quality of life of patients after surgery. With the continuous deepening of clinical research and practice and the updating of relevant theories, more detailed and reliable evidence-based medical evidence has been accumulated in the field of pelvic organ function protection in rectal cancer surgery, and has been continuously verified in the clinical real world at home and abroad. In order to further improve the awareness of domestic physicians on the protection of organ function during the treatment of rectal cancer, standardize the evaluation methods and surgical methods, reduce the incidence of organ dysfunction, and thus improve the quality of life of patients, Society of Colon & Rectal Surgeons of Chinese College of Surgeons of Chinese Medical Doctor Association, Section of Colorectal Surgery of Branch of Surgery of Chinese Medical Association, National Health Commission Capacity Building and Continuing Education Center Colorectal Surgery Committee, and Colorectal and Anal Function Surgeons Committee of China Sexology Association organized the discussion among relevant experts. On the basis of the 2021 edition of the Chinese Expert Consensus on the Protection of Pelvic Organ Function in Rectal Cancer Surgery, the recent evidence-based medical evidence was analyzed and summarized, and the definition, risk factors, evaluation methods, prevention and other issues of organ dysfunction after rectal cancer surgery were analyzed with reference to relevant domestic and foreign studies and combined with clinical practice. Proposed the diagnosis, evaluation and treatment of pelvic organ dysfunction in rectal cancer surgery, and finally formed the "Chinese expert Consensus on the protection of pelvic organ function in rectal cancer surgery (version 2025)".
Humans
;
Rectal Neoplasms/surgery*
;
Consensus
;
Pelvis/physiopathology*
;
Quality of Life
;
Postoperative Complications/prevention & control*
6.Standardized surgical procedure of proximally extended resection and sphincter-preserving surgery (Tianhe procedure®) for rectal cancer after radiotherapy (2025 version).
Chinese Journal of Gastrointestinal Surgery 2025;28(7):707-716
Tianhe procedure® is a functional sphincter-preserving surgical approach developed for rectal cancer patients following radiotherapy. This technique involves extended proximal resection of the colon beyond the pelvic cavity, followed by anastomosis of the non-irradiated proximal colon to the distal rectum or anal canal. This strategy aims to reduce the incidence of anastomotic complications and postoperative bowel dysfunction. However, there is currently a lack of standardized practice guideline for implementing Tianhe procedure® in China. Therefore, the Chinese Radiation Intestinal Injury Research Group, the Colorectal Surgery Group of Surgery Branch of the Chinese Medical Association, the Anorectal Branch of Chinese Medical Doctor Association, the Colorectal Cancer Committee of the Chinese Medical Doctor Association, and the Colorectal Cancer Committee of China Anti-cancer Association, and the Gastrointestinal Surgical Branch of Guangdong Medical Doctor Association, have jointly convened a panel of national experts to discuss and establish this standardized surgical procedure. This standard, based on the latest evidence from literature, research advancements, and expert experience, focuses on key aspects of the Tianhe procedure®, including its precise definition, indications, critical procedural steps, postoperative complications, and functional rehabilitation strategies. It aims to promote standardized implementation and broader clinical adoption of this innovative surgical technique.
Humans
;
Rectal Neoplasms/radiotherapy*
;
Anal Canal/surgery*
;
Anastomosis, Surgical/methods*
;
Organ Sparing Treatments/methods*
;
Rectum/surgery*
;
Postoperative Complications/prevention & control*
;
Digestive System Surgical Procedures/methods*
7.Expert consensus on the diagnosis and treatment of low anterior resection syndrome (2025 edition).
Chinese Journal of Gastrointestinal Surgery 2025;28(8):832-844
Low anterior resection syndrome (LARS) is a common bowel dysfunction syndrome following sphincter-preserving surgery for rectal cancer, characterized by stool storage dysfunction and evacuatory dysfunction. It has become a critical factor adversely affecting patients' quality of life and long-term clinical outcomes. Currently, the pathogenic mechanisms of LARS remain incompletely elucidated, and high-quality evidence to guide clinical practice is still lacking. However, emerging evidence suggests that strategic optimization across the clinical management pathway-including precision oncology planning, surgical technique selection, multidimensional symptom profiling, proactive prevention protocols, and comprehensive symptom management-may effectively reduce LARS severity and improve survivorship outcomes. Given the absence of consensus guidelines for LARS management among clinicians across China, the Chinese Society of Coloproctology (Chinese Medical Doctor Association) organized domestic experts in relevant fields. Through systematic review of global research findings, integration of international expertise and guidelines, and adaptation to domestic clinical realities, we developed the "Chinese Expert Consensus on the Diagnosis and Treatment of Low Anterior Resection Syndrome (2025 Edition)". This consensus elaborates on key aspects including the definition, clinical manifestations, risk factors, pathophysiological mechanisms, symptom assessment, treatment modalities, and prevention strategies for LARS, aiming to standardize the diagnosis and management of LARS in China.
Humans
;
Rectal Neoplasms/surgery*
;
Consensus
;
Postoperative Complications/therapy*
;
Quality of Life
;
Syndrome
;
China
;
Low Anterior Resection Syndrome
8.Key techniques of laparoscopic Roux-en-Y gastric bypass.
Zeyang WANG ; Zhi SONG ; Weizheng LI ; Pengzhou LI ; Shaihong ZHU ; Liyong ZHU
Journal of Central South University(Medical Sciences) 2025;50(2):251-258
Bariatric and metabolic surgery has become a primary treatment for decompensated obesity, with the number of procedures rapidly increasing in China in recent years. Various improved and novel surgical techniques have emerged. Given the characteristics of the Chinese obese population lower body mass index compared to Western populations and frequent pancreatic islet dysfunction laparoscopic Roux-en-Y gastric bypass remains one of the mainstream procedures in China. Although the Procedural Guideline for Laparoscopic Roux-en-Y Gastric Bypass (2019 Edition) has provided standardized surgical steps, mastering and routinely implementing the procedure in clinical practice continues to pose significant challenges. Compared to laparoscopic sleeve gastrectomy, laparoscopic Roux-en-Y gastric bypass is more technically demanding and requires a longer learning curve. To avoid suboptimal weight loss or severe postoperative complications resulting from non-standardized techniques, this article summarizes the authors' clinical experience, emphasizing key technical steps: creation of the gastric pouch, standardization of gastrojejunal and jejunojejunal anastomoses, hiatal closure, and full serosalization. These insights aim to improve procedural safety and therapeutic efficacy by offering a set of practical process optimization strategies.
Humans
;
Gastric Bypass/methods*
;
Laparoscopy/methods*
;
Obesity, Morbid/surgery*
;
Postoperative Complications/prevention & control*
;
China
;
Jejunum/surgery*
;
Gastrectomy/methods*
;
Anastomosis, Surgical/methods*
;
Weight Loss
9.Analyzing the reasons for and prevention of serious complications after general anesthesia in children with obstructive sleep apnea.
Lan CHEN ; Dabo LIU ; Jianwen ZHONG ; Shuyao QIU ; Yilong ZHOU
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(2):168-172
Objective:To explore the causes and preventive measures of respiratory arrest following general anesthesia in children with obstructive sleep apnea (OSA), in order to enhance the safety of OSA surgeries under general anesthesia. Methods:A retrospective analysis was conducted on the clinical and follow-up data of four pediatric cases that experienced respiratory arrest after general anesthesia for OSA at Shenzhen Hospital of Southern Medical University from March 2020 to March 2022. Results:All four children exhibited varying degrees of decreased blood oxygen saturation, cyanosis, and loss of consciousness after OSA surgery under general anesthesia, with one case experiencing respiratory and cardiac arrest. Through emergency rescue measures such as oxygen supplementation, suctioning, positive pressure ventilation, awakening, and cardiopulmonary resuscitation, all four children were stabilized. Follow-up after 2 to 6 months showed no complications. The main reasons for the occurrence are analyzed as: residual anesthetic drugs, characteristics of the OSA disease, and the unique aspects of the pediatric population. Conclusion:Children undergoing general anesthesia for OSA should be closely monitored for vital signs after surgery. If respiratory suppression occurs, active rescue measures should be taken to avoid serious consequences.
Humans
;
Sleep Apnea, Obstructive/surgery*
;
Anesthesia, General/adverse effects*
;
Retrospective Studies
;
Child
;
Postoperative Complications/prevention & control*
;
Male
;
Female
;
Child, Preschool
10.Perioperative safety assessment and complications follow-up of simultaneous bilateral cochlear implantation in young infants.
Xiaoge LI ; Pu DAI ; Yongyi YUAN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(5):413-424
Objective:To evaluate the perioperative safety and long-term complications of simultaneous bilateral cochlear implantation(BCI) in young infants, providing reference data for clinical BCI in young children. Methods:Seventy-four infants aged 6-23 months with congenital severe to profound sensorineural hearing loss who were candidates for cochlear implantation at the Department of Otolaryngology, Chinese PLA General Hospital between August 2018 and August 2019 were consecutively enrolled. Parents made the decision to implant either unilaterally or bilaterally. Participants were divided into unilateral cochlear implantation(UCI) group(before and after 12 months of age) and simultaneous BCI group(before and after 12 months of age). Safety indicators, including perioperative risk variables, complications, and other postoperative adverse events were monitored, with complications followed up for 5-6 years. Comparisons were made between the BCI and UCI, as well as between implantation before and after 12 months of age regarding perioperative safety and long-term complications. Results:A total of 40 BCI patients(23 before 12 months, 17 after 12 months) and 34 UCI patients(20 before 12 months, 14 after 12 months) were included in the study. Regarding perioperative risk variables, the BCI group showed significantly longer anesthesia duration, operative time, and greater blood loss compared to the UCI group, though less than twice that of the UCI group; no anesthetic complications occurred in either group; and there was no significant difference in postoperative hospital stay between the groups. Regarding surgical complications during the 5-year follow-up period, the BCI group experienced 7 complications(2 major, 5 minor), while the UCI group had 7 complications(1 major, 6 minor), with no statistical differences between groups. Regarding other postoperative adverse events, the BCI group demonstrated significantly higher total adverse event rates than the UCI group(80.0% vs 38.2%), with higher rates of moderate to severe anemia(60.0% vs 20.6%) and lower mean hemoglobin levels[(92.35±12.14) g/L vs(102.39±13.09) g/L]. No significant differences were found in postoperative fever rates(50.0% vs 52.9%) or C-reactive protein levels between groups. Within the BCI group, patients implanted before 12 months indicated notably higher rates of total adverse events(91.3% vs 64.7%), high fever(26.1% vs 0), and moderate to severe anemia(78.3% vs 35.3%) compared to those implanted after 12 months. Conclusion:Simultaneous BCI in young children under 2 years of age demonstrates controllable overall risks. Compared to UCI, while it shows no increase in anesthetic or surgical complications, it presents higher perioperative risks and adverse event rates, especially in patients implanted before 12 months of age, warranting special attention from medical staff.
Humans
;
Cochlear Implantation/methods*
;
Infant
;
Postoperative Complications
;
Hearing Loss, Sensorineural/surgery*
;
Follow-Up Studies
;
Male
;
Perioperative Period
;
Female
;
Cochlear Implants

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