1.Construction of a Nomogram model of C5 nerve root palsy following posterior approach cervical single-door enlargement kyphoplasty.
Shi-Tou LI ; Jun CHEN ; Yan-Feng ZHANG
China Journal of Orthopaedics and Traumatology 2025;38(7):705-710
OBJECTIVE:
To analyze the factors influencing the occurrence of C5 nerve root palsy after posterior approach cervical single-door enlargement kyphoplasty and construct a Nomogram-related prediction model.
METHODS:
A total of 255 patients with cervical spondylotic myelopathy who underwent posterior cervical single-door laminoplasty between May 2019 and February 2023 were selected as the research subjects. They were divided into the occurrence group (45 patients) and the non-occurrence group (210 patients) based on whether C5 nerve root palsy occurred after the operation. The general data of patients in the two groups were compared. The predictive value of statistically significant continuous variables was analyzed using receiver operating characteristic (ROC) curve analysis. The factors influencing patients' postoperative C5 nerve root palsy were analyzed using Logistic regression analysis. And the clinical efficacy of Nomogram model was assessed using decision curve analysis.
RESULTS:
Compared with the non-occurrence group, the patients in the occurrence group had a shorter disease duration, higher preoperative cervical curvature and spinal cord posterior displacement distance, and higher percentage of positive pathological reflexes, foraminal stenosis, and ossification of the posterior longitudinal ligament.The difference was statistically significant P<0.05. The area under the curve (AUC) for cervical curvature and posterior displacement of the spinal cord prior to surgery were 0.699 and 0.697, respectively. The optimal cutoff values were determined to be 21° and 3 mm, with statistically significant differences (P<0.05). Logistic regression analysis showed that abnormal electromyography OR=6.693, 95%CI(2.754, 16.264), P<0.001;preoperative cervical curvature OR=2.254, 95%CI(1.215, 2.920), P=0.003;foraminal stenosis OR=3.049, 95%CI(1.234, 7.530), P=0.016;ossification of the posterior longitudinal ligament OR=2.646, 95% CI(1.015, 6.899), P=0.047;and the distance of spinal cord posterior displacement OR=0.298, 95% CI(0.173, 0.513), P<0.001;which were all related factors influencing postoperative C5 nerve root palsy in patients with this disease. The C-index of the Nomogram model for predicting the risk of postoperative C5 nerve root palsy in patients was 0.861, with a 95% confidence interval of (0.795, 0.927). The risk threshold of this model was determined to be greater than 0.17.
CONCLUSION
Abnormal electromyography, preoperative cervical curvature, intervertebral foramen stenosis, ossification of the posterior longitudinal ligament, and the degree of posterior displacement of the spinal cord are all significant contributing factors to C5 nerve root palsy following posterior cervical single-door laminoplasty. A prediction model developed based on these factors demonstrates enhanced accuracy and substantial clinical application value.
Humans
;
Female
;
Nomograms
;
Male
;
Middle Aged
;
Aged
;
Kyphoplasty/adverse effects*
;
Cervical Vertebrae/surgery*
;
Spinal Nerve Roots
;
Adult
;
Postoperative Complications/etiology*
;
Paralysis/etiology*
2.Analysis of factors affecting the incidence of osteoarthritis following arthroscopic surgery for degenerative posterior horn of medial meniscus injuries.
Bin WANG ; Qiang-Bing DOU ; Xing-Xing LI ; Liang-Ye SUN
China Journal of Orthopaedics and Traumatology 2025;38(7):722-728
OBJECTIVE:
To investigate the risk factors associated with the development of knee osteoarthritis (OA) following arthroscopic surgery for degenerative lesions of the posterior horn of the medial meniscus.
METHODS:
Between January 2012 and January 2014, a retrospective analysis was conducted on 506 patients who underwent arthroscopic surgery for degenerative disease of the posterior horn of the medial meniscus. The cohort included 230 males and 276 females, aged from 32 to 58 years old with an average of (46.77±9.02) years old. According to the results of postoperative follow-up, patients were categorized into a knee osteoarthritis(OA) group and a non-OA group. The following parameters were recorded for each subject:gender, medial proximal tibial angle (MPTA), hip-knee-ankle angle (HKA), presence of bone edema on MRI, physical characteristics (including McMurray test results, locking symptoms, and medial knee tenderness points), meniscus protrusion, type of meniscus injury, and free body condition as observed via arthroscopy. Multivariate unconditional Logistic regression analysis was employed to investigate the associated factors influencing the 10-year postoperative incidence of knee osteoarthritis following surgery for degenerative injury of the posterior horn of the medial meniscus. Independent risk factors potentially influencing the development of postoperative OA were identified, and a nomogram-based predictive model for postoperative OA was established. The discriminatory ability and calibration accuracy of the model were assessed using the C-index and Hosmer-Lemeshow goodness-of-fit test, respectively. Furthermore, internal validation was performed using the bootstrap resampling method.
RESULTS:
Within a 10-year period following arthroscopic surgery, there were 123 patients in the OA group and 383 patients in the non-OA group. Significant differences were observed between two groups with respect to gender (χ2=5.156, P=0.023), MPTA<86.6° (χ2=21.671, P<0.001), varus lower limb alignment( χ2= 80.086, P<0.001). Additionally, meniscus extrusion (χ2=6.371, P=0.012), meniscus transverse tear (χ2=14.573, P<0.001), and bone edema detected on MRI(χ2=9.881, P=0.002) were identified as factors associated with the development of postoperative knee OA. The multifactorial Logistic regression analysis revealed that the lower limb line of force inversion OR=4.324, 95%CI (1.391, 13.443), P=0.011;MPTA <86.6°, OR=2.519, 95%CI (1.150, 5.519), P=0.021;transverse meniscus tear, OR=4.546, 95%CI (1.827, 11.310), P=0.001;meniscus ectropion, OR=5.401, 95%CI (1.992, 14.646), P=0.001;and bone edema manifestation on MRI OR=2.692, 95%CI (1.169, 6.200), P=0.020. They were independent risk factors associated with the development of postoperative OA. The area under the ROC curve predicted by the model was 0.927, 95%CI (0.903, 0.950). The Hosmer-Lemeshow goodness-of-fit test, used to evaluate the accuracy of the model, yielded P=0.689. Additionally, the internally sampled calibration curve demonstrated good consistency with the actual postoperative OA outcomes.
CONCLUSION
Varus alignment of the lower extremity, MPTA <86.6°, transverse meniscus tear, lateral meniscus injury, and bone marrow edema observed on MRI were independent risk factors for the development of knee osteoarthritis following arthroscopic surgery. Additionally, the prognostic model demonstrated excellent predictive performance.
Humans
;
Male
;
Female
;
Middle Aged
;
Arthroscopy/adverse effects*
;
Adult
;
Retrospective Studies
;
Tibial Meniscus Injuries/surgery*
;
Osteoarthritis, Knee/epidemiology*
;
Risk Factors
;
Menisci, Tibial/surgery*
;
Incidence
;
Postoperative Complications/epidemiology*
3.Sparing piriformis and internus repairing externus vs. other conventional approaches for hip hemiarthroplasty: A report of early outcomes from a single UK trauma unit.
Michael APOSTOLIDES ; William THOMAS ; Darren LEONG ; Bogdan ROBU ; Nimesh PATEL
Chinese Journal of Traumatology 2025;28(5):324-329
PURPOSE:
Over 30,000 hip hemiarthroplasties for neck of femur fractures are performed annually in the United Kingdom (UK). The national recommendation is via the lateral approach, to reduce the risk of dislocation, with the potential expense of reduced function and mobility post-operatively. Muscle-sparing approaches, such as SPAIRE (sparing piriformis and internus repairing externus), have been invented to address the issue of dislocation.
METHODS:
We performed a retrospective data collection at a single center with a high annual volume of hip hemiarthroplasties over 12 months. All patients who had hip hemiarthroplasty as their primary treatment were included. Patients who passed away and were non-ambulant before their surgery were excluded from the study. Our primary outcome was the dislocation rate and secondary outcomes were the time to mobilization after surgery and the duration of surgery. Statistical analysis was performed using XLSTAT software.
RESULTS:
We identified 194 cases, and these were divided into 3 groups based on the surgical approach: SPAIRE (n = 43), lateral (n = 97), and posterior (n = 54). Groups had similar demographics and a minimum 3-month follow-up after surgery. There were no dislocations in the SPAIRE group, whereas the dislocation rate for the other 2 groups was 2.5% in the lateral and 9.1% in the posterior groups at 6 months post-surgery. There was an earlier return to mobility in the SPAIRE (1.4 day) compared to the 2 other groups ( 2 days and 2.6 days). Average surgical times were very similar among all 3 groups (74 min vs. 79 min vs. 71 min).
CONCLUSION
The SPAIRE approach seems to be safe and provides a low risk of dislocation and good post-operative function for patients undergoing hip hemiarthroplasties.
Humans
;
Hemiarthroplasty/methods*
;
Retrospective Studies
;
Female
;
Male
;
Aged
;
United Kingdom
;
Femoral Neck Fractures/surgery*
;
Middle Aged
;
Treatment Outcome
;
Aged, 80 and over
;
Arthroplasty, Replacement, Hip/methods*
;
Trauma Centers
;
Hip Dislocation/prevention & control*
;
Postoperative Complications/prevention & control*
4.Application of the modified Byars staged procedure for severe hypospadias repair.
Qi-Gen XIE ; Ting-Ting XUE ; Xu-Ren CHEN ; Zhao-Ying LI ; Zhe XU ; Zuo-Qing LI ; Peng LUO
Asian Journal of Andrology 2025;27(1):65-71
This study aimed to introduce a modified Byars staged procedure and investigate its application value in patients with severe hypospadias. We retrospectively analyzed the clinical data of patients with severe hypospadias admitted to the First Affiliated Hospital of Sun Yat-sen University (Guangzhou, China) between October 2012 and October 2022. In total, 31 patients underwent the conventional Byars procedure (conventional group), and 45 patients underwent the modified Byars staged procedure (modified group). Our modified strategy was built upon the standard Byars procedure by incorporating glansplasty during the first stage and employing a Y-shaped flap in conjunction with a glandular tunnel for urethroplasty during the second stage. Notably, there were no statistically significant differences in the preoperative baseline characteristics, duration of surgery, amount of blood loss, or occurrence of postoperative complications, including urethral fistula, stricture and diverticulum, or penile curvature, between the conventional and modified groups. However, there was a significantly lower incidence of coronal sulcus fistula (0 vs 16.1%, P = 0.02) and glans dehiscence (0 vs 12.9%, P = 0.02) in the surgical group than that in the conventional group. In addition, the modified group exhibited a notably greater rate of normotopic urethral opening (100.0% vs 83.9%, P = 0.01) and a higher mean score on the Hypospadias Objective Penile Evaluation (HOPE; mean ± standard error of mean: 8.6 ± 0.2 vs 7.9 ± 0.3, P = 0.02) than did the conventional group. In conclusion, the modified Byars staged procedure significantly reduced the risks of glans dehiscence and coronal sulcus fistula. Consequently, it offers a promising approach for achieving favorable penile esthetics, thereby providing a reliable therapeutic option for severe hypospadias.
Humans
;
Hypospadias/surgery*
;
Male
;
Retrospective Studies
;
Urologic Surgical Procedures, Male/methods*
;
Child, Preschool
;
Child
;
Postoperative Complications/etiology*
;
Urethra/surgery*
;
Plastic Surgery Procedures/methods*
;
Surgical Flaps
;
Penis/surgery*
;
Treatment Outcome
;
Infant
5.Association between maximal urethral length preservation and postoperative continence after robot-assisted radical prostatectomy: a meta-analysis and systematic review.
Tian-Yu XIONG ; Zhan-Liang LIU ; Hao-Yu WU ; Yun-Peng FAN ; Yi-Nong NIU
Asian Journal of Andrology 2025;27(2):225-230
Urinary incontinence is a common complication following robot-assisted radical prostatectomy (RARP). Urethral length has been identified as a factor affecting postoperative continence recovery. In this meta-analysis, we examined the association between use of the maximal urethral length preservation (MULP) technique and postoperative urinary continence in patients undergoing RARP. We conducted a comprehensive search of PubMed, Web of Science, Embase, and the Cochrane Library up to December 31, 2023. The quality of the literature was assessed using the Newcastle-Ottawa Scale. A random-effects meta-analysis was performed to synthesize data and calculate the odds ratio (OR) from eligible studies on continence and MULP. Six studies involving 1869 patients met the eligibility criteria. MULP was positively associated with both early continence (1 month after RARP; Z = 3.62, P = 0.003, OR = 3.10, 95% confidence interval [CI]: 1.68-5.73) and late continence (12 months after RARP; Z = 2.34, P = 0.019, OR = 2.10, 95% CI: 1.13-3.90). Oncological outcomes indicated that MULP did not increase the overall positive surgical margin rate or the positive surgical margin status at the prostate apex (both P > 0.05). In conclusion, the use of the MULP technique in RARP significantly improved both early and late postoperative continence outcomes without compromising oncological outcomes.
Humans
;
Prostatectomy/adverse effects*
;
Robotic Surgical Procedures/methods*
;
Male
;
Urethra/surgery*
;
Urinary Incontinence/prevention & control*
;
Postoperative Complications/etiology*
;
Prostatic Neoplasms/surgery*
;
Organ Sparing Treatments/methods*
6.Comparative analysis of isolated male epispadias: concealed versus nonconcealed cases in a Chinese tertiary hospital.
Jia-Yi LI ; Bo YU ; Meng-Cheng YANG ; Zong-Han LI ; Hong-Cheng SONG ; Wei-Ping ZHANG
Asian Journal of Andrology 2025;27(4):502-507
Isolated male epispadias typically presents with preputial defects and dorsal urethral dehiscence. A less common subtype, known as concealed epispadias, is distinguished by an intact prepuce. Despite its clinical relevance, there is limited literature on this variant. In this study, we retrospectively analyzed the clinical data of 86 pediatric patients with isolated male epispadias treated in Beijing Children's Hospital (Beijing, China) from May 2004 to July 2023, including 19 cases of concealed epispadias and 67 of nonconcealed epispadias. We compared clinical characteristics, preoperative diagnostics, surgical techniques, postoperative outcomes, and sexual function during follow-up between the concealed and nonconcealed groups. No significant differences were observed between the two groups regarding surgical methods, postoperative complications, or rates of urinary incontinence. However, notable distinctions were found in the age at initial diagnosis, timing of surgery, frequency of incontinence, location of the urethral meatus, and postoperative urinary incontinence scores (all P < 0.05). Given the absence of penopubic epispadias in concealed cases, we categorized glans and penile epispadias within nonconcealed epispadias as distal epispadias ( n = 40) and subsequently compared them with concealed epispadias cases. The postoperative urinary incontinence scores did not differ significantly between the concealed and distal epispadias groups. These findings suggest that concealed epispadias represents a relatively milder form of the condition, characterized by the absence of penopubic involvement, lower rates of urinary incontinence, and favorable surgical outcomes. However, the intact prepuce in concealed cases underscores the need for careful identification and early diagnosis.
Humans
;
Male
;
Retrospective Studies
;
Epispadias/classification*
;
China
;
Tertiary Care Centers
;
Child, Preschool
;
Child
;
Postoperative Complications/epidemiology*
;
Urinary Incontinence/epidemiology*
;
Urethra/surgery*
;
Infant
;
Penis/surgery*
;
Adolescent
;
Urologic Surgical Procedures, Male/methods*
;
East Asian People
7.Conservative treatment of pathological fracture after multiple odontogenic keratocyst surgery: a case report and literature analysis.
Chen XU ; Hongguang CHANG ; Qiang SHAO ; Yonghai SONG
West China Journal of Stomatology 2025;43(1):144-150
Pathological fractures after jaw cyst surgery are rare clinically but are a serious complication. Once a pathological fracture occurs, treatment time and economic costs increase, and doctors face difficulty in handling it. This article reports a case of a patient with mandibular pathological fractures after multiple odontogenic keratocyst surgery of the jaw. Mandibular lesions were located in the bilateral mandibular angles and had macrocystic changes. We adopted a conservative treatment plan, and the treatment effect was good. We also discussed and analyzed relevant literature to provide a reference for clinicians.
Humans
;
Odontogenic Cysts/surgery*
;
Conservative Treatment
;
Postoperative Complications/therapy*
;
Mandibular Fractures/etiology*
;
Fractures, Spontaneous/etiology*
;
Male
;
Female
8.Management of accidental tooth root displacement into the mandibular canal during tooth extraction.
West China Journal of Stomatology 2025;43(6):789-796
The accidental displacement of tooth roots into the mandibular canal is a serious complication during tooth extractions in oral and maxillofacial surgery, often resulting in direct damage to the structural and functional integrity of the inferior alveolar neurovascular bundle (IANB). This article reviews the anatomical features of the mandibular canal, the IANB, and adjacent tooth roots; identifies high-risk factors and anatomically vulnerable sites for root displacement; and outlines the clinical manifestations and radiographic characteristics of intraoperative root intrusion into the mandibular canal. Furthermore, management principles, surgical approaches and techniques, inferior alveolar nerve injury treatment, and prognostic considerations are discussed. The aim of this review is to provide a comprehensive clinical reference for improving surgical outcomes, and reducing postoperative complications.
Humans
;
Tooth Extraction/adverse effects*
;
Mandible/surgery*
;
Tooth Root
;
Mandibular Nerve/anatomy & histology*
;
Postoperative Complications/prevention & control*
;
Intraoperative Complications
;
Mandibular Nerve Injuries/etiology*
9.Risk factors for erectile dysfunction after penile fracture and surgical repair: 12 years of clinical experience.
Mehmet OZTURK ; Muharrem BATURU ; Ozlem BASGUT ; Omer TURGUT ; Yasin KURT ; Omer BAYRAK
Asian Journal of Andrology 2025;27(6):738-742
Penile fracture is a rare urological emergency that may cause erectile dysfunction (ED). We analyzed the factors affecting erectile function in patients who underwent surgical repair for the management of penile fractures. Eighty-two patients who underwent penile fracture surgery in the Department of Urology, University of Gaziantep (Gaziantep, Türkiye) between January 2012 and January 2023 were evaluated. Age, body mass index, time elapsed from the incident of penile fracture to surgery, size, laterality, level of the defect, causes of fracture, presenting signs and symptoms, and relevant complications were recorded. Erectile function of the patients was evaluated preoperatively and at postoperative 3 rd and 6 th months according to the International Index of Erectile Function-5 (IIEF-5) scoring system. The factors decreasing the erection quality of the patients after surgical repair of penile fractures were investigated using IIEF-5 scoring system. Only age, defect size, and time elapsed from fracture onset to surgery were found to be effective on the occurrence of ED ( P = 0.005, P < 0.001, and P < 0.001, respectively). In the receiver operating characteristic (ROC) analysis, the cut-off values were 12.5 mm for defect size ( P < 0.001), 8.5 h for the time elapsed from fracture onset to surgery ( P = 0.036), and 40.5 years for the age of the patients ( P = 0.005). Delayed surgery, defect size, and advanced age had significant and negative effects on erectile function in cases of penile fracture. Before repair of the defect, patients should be given appropriate counseling about the possibility of ED, and early penile rehabilitation should be initiated.
Humans
;
Male
;
Erectile Dysfunction/epidemiology*
;
Penis/surgery*
;
Adult
;
Middle Aged
;
Risk Factors
;
Postoperative Complications/etiology*
;
Young Adult
;
Rupture/surgery*
;
Age Factors
;
Aged
;
Penile Erection
;
Retrospective Studies
10.Left bundle branch pacing in a patient with decreased cardiac function after transcatheter aortic valve replacement.
Xinghong LI ; Jubo JIANG ; Sheng'an SU ; Fang ZHOU
Journal of Zhejiang University. Medical sciences 2025;54(2):149-153
A case of an elderly patient with severe aortic insufficiency who carried high risks for surgical valve replacement. After a detailed preoperative evaluation, the patient successfully received transapical transcatheter aortic valve replacement. Postoperatively, complete left bundle branch block developed, resulting in impaired left ventricular function. Despite guideline-directed medical therapy for heart failure, cardiac function showed no significant recovery. At 4.5 months post-surgery, left bundle branch pacing was performed, leading to a marked improvement in cardiac function.
Aged
;
Humans
;
Male
;
Aortic Valve Insufficiency/surgery*
;
Bundle-Branch Block/etiology*
;
Cardiac Pacing, Artificial
;
Postoperative Complications/therapy*
;
Transcatheter Aortic Valve Replacement/adverse effects*

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