Objective:To investigate the effect of lumbar sympathetic ganglion block (LSGB) on postoperative ileus (POI) in patients undergoing colonic surgery.Methods:Ninety patients scheduled for elective laparoscopic colonic surgery in the same treatment group at the Nanjing First Hospital from March 2022 to August 2023 were selected and randomly divided into a control group and an observation group using a random number table, with 45 patients in each group. The observation group received ultrasound-guided LSGB before anesthesia, while the control group received no intervention. Both groups received standardized anesthesia protocols and management after entering the operating room. The time to gastrointestinal motility recovery (first defecation time), first flatus time, first feeding time, number of cases requiring gastric tube decompression, postoperative hospital stay, number of cases with nausea and vomiting, intraoperative additional and titrated sufentanil dosage, remifentanil dosage, first patient-controlled intravenous analgesia (PCIA) press time, sufentanil dosage at 4, 8, 12, 16, and 24 hours postoperatively, and the number of analgesic pump presses were recorded.Results:Compared with the control group, the observation group had shorter first defecation and flatus times, earlier first feeding time, shorter postoperative hospital stay, and fewer cases of nausea (all P<0.05). The observation group also had less intraoperative sufentanil supplementation and titration, later first PCIA press time (all P<0.05), and significantly fewer sufentanil dosages and analgesic pump presses at 4, 8, 12, 16, and 24 hours postoperatively compared with the control group (all P<0.05). Conclusions:LSGB reduces the incidence of POI in colonic surgery patients, decreases opioid use, and shortens hospital stay.

Objective:To investigate the effect of lumbar sympathetic ganglion block (LSGB) on postoperative ileus (POI) in patients undergoing colonic surgery.Methods:Ninety patients scheduled for elective laparoscopic colonic surgery in the same treatment group at the Nanjing First Hospital from March 2022 to August 2023 were selected and randomly divided into a control group and an observation group using a random number table, with 45 patients in each group. The observation group received ultrasound-guided LSGB before anesthesia, while the control group received no intervention. Both groups received standardized anesthesia protocols and management after entering the operating room. The time to gastrointestinal motility recovery (first defecation time), first flatus time, first feeding time, number of cases requiring gastric tube decompression, postoperative hospital stay, number of cases with nausea and vomiting, intraoperative additional and titrated sufentanil dosage, remifentanil dosage, first patient-controlled intravenous analgesia (PCIA) press time, sufentanil dosage at 4, 8, 12, 16, and 24 hours postoperatively, and the number of analgesic pump presses were recorded.Results:Compared with the control group, the observation group had shorter first defecation and flatus times, earlier first feeding time, shorter postoperative hospital stay, and fewer cases of nausea (all P<0.05). The observation group also had less intraoperative sufentanil supplementation and titration, later first PCIA press time (all P<0.05), and significantly fewer sufentanil dosages and analgesic pump presses at 4, 8, 12, 16, and 24 hours postoperatively compared with the control group (all P<0.05). Conclusions:LSGB reduces the incidence of POI in colonic surgery patients, decreases opioid use, and shortens hospital stay.

Objective:To analyze the efficacy of endoscopic laryngeal mask in obese patients undergoing upper gastrointestinal endoscopic mucosal resection (EMR).Methods:Adopting a prospective research approach, 90 obese patients who underwent upper gastrointestinal EMR from July 2020 to May 2022 in Nanjing First Hospital, Nanjing Medical University were selected. The patients were divided into endoscopic laryngeal mask group (using general anesthesia with endoscopic laryngeal mask ventilation) and nasal catheter group (using conventional non intubated intravenous anesthesia) by random digits table method with 45 cases in each. The EMR time; minimum pulse oxygen saturation (SpO 2) during perioperative period; changes of SpO 2, mean arterial pressure (MAP) and heart rate during perioperative period; palinesthesia time; postoperative postanesthesia care unit (PACU) residence time; adverse reactions; satisfaction levels of doctor and patient satisfaction were recorded. Results:There were no statistical difference in EMR time and postoperative PACU residence time between two groups ( P>0.05). There were no statistical difference in minimum SpO 2 preoperative and anesthesia induction period between two groups ( P>0.05); the minimum SpO 2 EMR period in endoscopic laryngeal mask group was significantly higher than those in nasal catheter group (0.990 ± 0.010 vs. 0.951 ± 0.037), and there was statistical difference ( P<0.01). There were no statistical difference in heart rate and MAP during perioperative period between two groups ( P>0.05). There were no statistical difference in SpO 2 entering the operating room and leaving the PACU between two groups ( P>0.05), SpO 2 immediately after endoscopic insertion and at the end of surgery in endoscopic laryngeal mask group was significantly higher than that in nasal catheter group (0.989 ± 0.009 vs. 0.976 ± 0.011 and 0.987 ± 0.010 vs. 0.981 ± 0.009), and there was statistical difference ( P<0.01). The palinesthesia time in endoscopic laryngeal mask group was significantly longer than that in nasal catheter group: (6.7 ± 1.1) min vs. (4.6 ± 1.2) min, and there was statistical difference ( P<0.01). Both groups did not experience aspiration, hoarseness or airway spasm. There were no statistical difference in the incidences of pharyngalgia, bradycardia, hypotension, abdominal pain and bloating, postoperative nausea and vomiting between two groups ( P>0.05). The incidence of bucking and body movement in endoscopic laryngeal mask group was significantly lower than that in nasal catheter group: 2.2% (1/45) vs. 24.4% (11/45), and there was statistical difference ( P<0.01). There were no statistical difference in the satisfaction level of patient between two groups ( P>0.05); the satisfaction levels of anesthesiologists and endoscopists in endoscopic laryngeal mask group were significantly higher than those in nasal catheter group: 95.6% (43/45) vs. 66.7% (30/45) and 88.9% (40/45) vs. 71.1% (32/45), and there were statistical differences ( P<0.01 or <0.05). Conclusions:The application of endoscopic laryngeal mask in upper gastrointestinal EMR in obese patients can effectively improve the hypoxia caused by insufficient ventilation. At the same time, it will not cause drastic fluctuations in hemodynamics, and it does not increase the incidence of throat discomfort, but it slightly extends the awakening time.

Objective To evaluate the effect of endoscopic laryngeal mask on perioperative airway management and postoperative recovery in patients undergoing gastric endoscopic submucosal dissection(ESD).Methods Ninety patients,aged 18-64 years,BMI 18-25 kg/m2,ASA physical statusⅠorⅡ,who underwent elective gastric ESD were randomly divided into two groups:the endoscopic laryngeal mask group(group E)and the endotracheal tube group(group C),45 patients in each group.After induction of general anesthesia,group E received endoscopic laryngeal mask airway ventilation,and the endoscope was inserted through the endoscopic channel of the laryngeal mask,group C received tracheal intubation,and the endoscopy was inserted through the mouth.The successful time and one-time success rate of intubation,and the insertion time and withdrawal rate of endoscopy were recorded.The operative time,extubation time and PACU residence time were recorded.HR,MAP were recorded when the patient entered the room(T0),at the time of intubating(T1),inserting gastroscopy(T2),exiting gastroscopy(T3),extubation(T4),and leaving PACU(T5).The average airway pressure and peak airway pressure at T1-T3 were recorded.The airway sealing pressure and endoscopic view grading system(EVGS)grading of group E were recorded before and after changing the position,and at the end of surgery.The adverse reactions and the satisfaction of anesthesiologists and gastroenterologists were recorded.Results Compared with T0,HR and MAP were significantly increased at T1 and T4 between the two groups(P＜0.05).Compared with group C,the suc-cessful time of intubation,the extubation time,and PACU residence time were significantly shortened,HR and MAP were significantly decreased at T1 and T4,the incidence of choking cough during extubation,post-operative pharyngeal pain,and hoarseness were significantly decreased(P＜0.05).There were no signifi-cant differences in the one-time success rate of intubation,the insertion time and withdrawal rate of endosco-py between the two groups.Endoscopic laryngeal mask showed good sealing and alignment in group E.Conclusion Endoscopic laryngeal mask could shorten the success time of establishment of artificial airway in patients with gastric ESD,without interfering with digestive endoscopy operations,shorten extubation time and PACU retention time,maintain intraoperative hemodynamic stability,and reduce adverse reactions.