1.Philippine clinical practice guidelines on the management of urolithiasis in adults.
Sylvia Karina L. Alip ; Daniel Guevarra ; Jason Arboleda ; Rowena Plumo ; Aldrich Ivan Burog ; Marie Carmela M. Lapitan
Philippine Journal of Urology 2026;36(1):1-14
INTRODUCTION
Urinary stone disease remains a significant global and national health concern. This underscores the need for measures to improve disease outcomes. The development and implementation of clinical practice guidelines for urolithiasis was deemed essential due to variations in practice, the evolving urologic field with its emerging interventions, which may have significant cost implications.
METHODSThe CPG was developed following the GRADE Adolopment method, the CORE GRADE Approach and the GRADE Evidence to Decision framework, and utilized the Technical Manual for Clinical Practice Guideline Development of the Department of Health (2nd edition). The guideline development group was organized after review and management of the members' conflict of interest declarations. Clinical questions were prioritized and a systematic search and synthesis of the relevant literature to answer the questions was done. Considering the balance of benefits and harms, certainty of the evidence, cost and cost effectiveness, accessibility, acceptability and feasibility of the interventions, the guideline panel developed recommendations by consensus.
RESULTSThe CPG addresses eleven priority clinical questions involving diagnosis and treatment of acute flank pain due to suspected urolithiasis among adults, minimally invasive treatment of nephrolithiasis measuring 1-2 cm and the use of alpha blockers after ESWL through twelve recommendations and one good practice statement.
CONCLUSIONThe Philippine CPG on the management of urolithiasis in adults provides actionable recommendations to address important clinical questions on the diagnosis and management of urinary stone disease. The full text of the clinical practice guideline may be viewed and downloaded from https://doh.gov.ph/dpcb/doh-approved-cpg/
Human ; Adult ; Urolithiasis
2.Training satisfaction among urology residents in the Philippines: Validation of a structured questionnaire and national cross-sectional survey.
Miguel Luis H. Bolong ; Genlinus D. Yusi ; Ronan C. Cuaresma ; Jose Rizalito C. Catipay ; Gavino N. Mercado Jr. ; Michael Francis V. Gaston ; Cristopher F. Perez ; Aristotle Bernard M. Roque ; Meliton D. Alpas III ; Rudolfo I. de Guzman
Philippine Journal of Urology 2026;36(1):15-20
BACKGROUND AND OBJECTIVE
Residency satisfaction is an important indicator of training quality and may influence physician well-being and performance. Surgical trainees are generally reported to have lower satisfaction compared to other specialties. This study assessed satisfaction among urology residents in the Philippines and evaluated a structured questionnaire for measuring training experience.
MATERIALS AND METHODSA cross-sectional survey was conducted among residents in accredited urology programs (2024-2024-5). A 12-domain Likert-scale questionnaire was developed and validated. Internal consistency and test-retest reliability were assessed. Satisfaction scores were analyzed overall and across subgroups.
RESULTSA total of 106 residents participated. The instrument demonstrated good internal consistency (Cronbach's α = 0.870) and strong test-retest reliability (r = 0.896). Overall satisfaction was high (52.41 5.4/60). Clinical exposure was the highest-rated domain, while work-life balance was the lowest. No significant differences were observed by gender, training year, or institution type. Key areas for improvement were case exposure and academic learning.
CONCLUSIONUrology residents in the Philippines report high overall satisfaction. The validated questionnaire is reliable and useful for assessing multidimensional aspects of residency training. Improvements in case exposure, academic support, and work-life balance may further enhance training quality.
Human ; Cross-sectional Studies ; Internship And Residency
3.Association between preoperative hydronephrosis and perioperative outcomes among patients undergoing percutaneous nephrolithotomy: A single-center prospective cohort study.
Dainiel Edgar A. Reyes ; Albert T. Aquino
Philippine Journal of Urology 2026;36(1):21-28
BACKGROUND
Staghorn calculi are complicated renal stones that are frequently linked to hydronephrosis, a parameter that can have a major impact on the results of surgery. Percutaneous nephrolithotomy (PCNL) is widely recognized as the gold standard for treating large kidney stones and staghorn calculi. Data on the effect of preoperative hydronephrosis on PCNL perioperative outcomes is still limited.
OBJECTIVEThis study aimed to investigate the association between preoperative hydronephrosis and perioperative outcomes among patients undergoing PCNL in a tertiary government hospital in Manila.
METHODSA single-center prospective cohort study was conducted, involving 90 patients diagnosed with staghorn calculi and scheduled for elective PCNL. Patients were categorized into two groups based on the presence or absence of moderate-to-severe hydronephrosis as determined by preoperative imaging. Perioperative outcomes, including total operative time, access time, lithotripsy time, and perioperative complications such as bleeding and sepsis, were evaluated. Data were analyzed using linear and logistic regression models to assess associations between hydronephrosis and perioperative outcomes.
RESULTSThe presence of hydronephrosis was associated with a statistically significant reduction in access time (p = 0.036), likely due to the dilation of renal structures facilitating easier entry. However, hydronephrosis was linked to a borderline significant reduction in lithotripsy rate (p = 0.051), indicating potential challenges in stone fragmentation. No significant association was found between hydronephrosis and total operative time or perioperative complications, such as bleeding and sepsis.
CONCLUSIONWhile hydronephrosis may make kidney access and other technical aspects of PCNL easier, it may also make stone fragmentation more difficult. Larger stone size and stone location were significant predictors of longer operative times and slower lithotripsy rates, underscoring their critical role in surgical outcomes.
Human ; Staghorn Calculi ; Nephrolithotomy, Percutaneous ; Kidney Calculi ; Hydronephrosis
4.Analysis of risk factors for developing sepsis in patients who underwent percutaneous nephrolithotomy at the National Kidney and Transplant Institute: A retrospective study.
Martin Joseph L. Alcaraz ; Arturo P. Castro Jr.
Philippine Journal of Urology 2026;36(1):29-39
OBJECTIVE
This study aimed to identify the different risk factors for developing sepsis in patients undergoing percutaneous nephrolithotomy
METHODSThis is a case-control study of all patients who underwent percutaneous nephrolithotomy in the National Kidney and Transplant Institute from 2017 to 2021. Demographic, stone characteristics, perioperative data and post-operative parameters were recorded. The association of clinical variables and sepsis was determined using logistic regression analysis.
RESULTSA total of 536 patients who underwent percutaneous nephrolithotomy were included in the study with 58 of them suffering from sepsis with a prevalence rate of 9.9%. The majority [392 (67.82%)] of the patients were 31-59 years old. Majority of patients suffering from sepsis also belonged to the same age group were predominantly male [33 (56.9%)], mostly diabetic [15 (26.32%)] and hypertensive [14 (24.56%)] and underwent previous PCNL [49 (8.45%)]. Imaging of patients who had sepsis showed staghorn calculi [30 (51.72%)] with mild [20 (34.48%)] and moderate [23 (39.66%)] seen on imaging. Patients who were requiring transfusion post operatively (Grade II Clavien-Dindo Classification) were seen to have sepsis.
CONCLUSIONThe following factors are contributory to the development of sepsis: a high Guy's stone score, high degree of obstruction or hydronephrosis, previous stone surgery and a higher volume of blood loss.
Human ; Nephrolithotomy, Percutaneous ; Sepsis ; Hydronephrosis
5.The battle within: Command hallucinations driving recurrent urethral foreign body insertion in schizophrenia – A case report.
Sherwin Chester R. Tape ; Christine Joy G. Castillo ; Aristotle Bernard M. Roque ; Ceasar Ballesteros
Philippine Journal of Urology 2026;36(1):40-44
OBJECTIVES
To present a rare case of recurrent urethral and intravesical foreign body insertion driven by command hallucinations in schizophrenia, to describe the surgical and psychiatric management strategies employed, and to emphasize the importance of interdisciplinary care and treatment adherence in preventing recurrence.
METHODSReported here is the case of a 37-year-old male with schizophrenia who presented with multiple episodes of urethral and intravesical foreign body insertion over a six-year period (2018–2025). Inserted objects included metallic wires, electrical cords, and a LED Christmas light rope, each requiring surgical removal via cystoscopy or open cystotomy. Psychiatric evaluation revealed poor adherence to antipsychotic medication, with recurrent episodes associated with command hallucinations. Psychiatric management was reinitiated with olanzapine and structured follow-up to improve treatment compliance.
RESULTSSix documented episodes of self-inflicted urethral and intravesical trauma required repeated urologic interventions. Despite recurrent instrumentation and foreign body insertion, serial cystoscopic evaluations demonstrated preserved urethral and bladder integrity without evidence of stricture formation. The most recent episode required open cystotomy for removal of a coiled LED light rope, which was successfully extracted without complications. Following coordinated psychiatric management and improved adherence to antipsychotic therapy, the patient remained asymptomatic and free of recurrence at three months follow-up.
CONCLUSIONThis case highlights the unusual preservation of urethral integrity despite recurrent traumatic self-insertion. Effective management requires sustained psychiatric stabilization, multidisciplinary collaboration, and strict treatment adherence. Integration of psychiatric and urologic care is essential to prevent recurrence and improve long-term outcomes in patients with schizophrenia-related self-inflicted genitourinary injury.
Human ; Male ; Adult: 25-44 Yrs Old ; Schizophrenia ; Cystoscopy ; Self-injurious Behavior ; Psychotic Disorders ; Antipsychotic Agents ; Olanzapine ; Constriction, Pathologic ; Hallucinations ; Urinary Bladder ; Foreign Bodies
6.Bilateral single-curvilinear inguinal incisions in advanced penile cancer: A novel approach to inguinal and pelvic lymphadenectomy.
Porferio P. Serrano III ; Michael Jonathan R. Latayan
Philippine Journal of Urology 2026;36(1):45-48
BACKGROUND
Penile squamous cell carcinoma (SCC) is rare in high-income regions but remains a significant oncologic burden worldwide. Nodal involvement is the most important prognostic factor, and early identification is critical.
THE CASEA 56-year-old circumcised male presented with a six-month history of a progressively enlarging, foul-smelling fungating penile mass and bilateral inguinal lymphadenopathy. Biopsy confirmed moderately differentiated SCC. Imaging showed large bilateral inguinal nodal disease without distant metastasis. Laboratory findings revealed leukocytosis, thrombocytosis, and mildly deranged coagulation parameters. The patient underwent total penectomy with perineali urethrostomy, followed by bilateral inguinal and pelvic lymph node dissection through single-curvilinear incisions. Frozen-section analysis confirmed extensive bilateral nodal metastasis. Postoperatively, a localized left inguinal surgical site infection was treated conservatively. He was discharged on postoperative day seven with drains in situ and was recommended adjuvant chemoradiotherapy in accordance with NCCN Guidelines.
CONCLUSIONThis case highlights the challenges of managing advanced penile SCC with bulky bilateral inguinal metastasis and demonstrates the utility of single-curvilinear inguinal incisions for comprehensive lymphadenectomy. Early recognition, accurate staging, and guideline-based multimodal treatment remain essential for optimizing outcomes.
Human ; Male ; Middle Aged: 45-64 Yrs Old ; Carcinoma, Squamous Cell ; Lymph Node Excision
7.Breaking barriers in robotic surgery: Efficiency and safety of a low-cost, single-port extraperitoneal robotic-assisted radical prostatectomy
Rajiv H. Kalbit ; Enrique Ian S. Lorenzo
Philippine Journal of Urology 2025;35(2):81-87
INTRODUCTION AND OBJECTIVE
The increasing demand for cost-effective surgical techniques has driven innovations in robotic-assisted radical prostatectomy (RARP). While single-port robotic surgery reduces invasiveness and improves cosmesis, its widespread use is limited by high costs and technical constraints. This study evaluates the safety, feasibility and cost-effectiveness of extraperitoneal single-port robotic-assisted radical prostatectomy (espRARP) using a modified Da Vinci Si HD system, employing a wound protector and surgical glove as a low-cost multi-channel laparoscopic port.
METHODSTen patients with localized prostate cancer underwent espRARP using a three-arm Da Vinci Si system and side docking to enhance instrument access. A homemade multi-channel port was constructed using an Alexis® wound protector and surgical gloves. Perioperative outcomes—including operative time, blood loss, complications and oncologic results were analyzed descriptively.
RESULTSAll cases were completed without conversion to open surgery. The mean operative time was 215.8 minutes with an estimated blood loss of 200 mL. No positive surgical margins were recorded, and 20% of patients exhibited pathological upgrading. The average hospital stay was 3.4 days. One patient developed a Clavien–Dindo II complication; no major complications occurred
LIMITATIONSThis pilot study is limited by its small sample size (n = 10), single-surgeon, single institution design, short follow-up period, and absence of functional outcome assessment. Only descriptive analysis was performed without statistical comparison.
CONCLUSIONThe modified espRARP technique using a low-cost glove-port and three-arm Da Vinci Si system is safe, feasible and cost-efficient. Comparable perioperative and oncologic outcomes to conventional multi-port and proprietary single-port systems were achieved at a fraction of the cost. This approach provides a practical and accessible alternative for robotic prostatectomy in resource-limited healthcare settings.
Human ; Prostatectomy ; General Surgery ; Prostatic Neoplasms
8.Diagnosis and treatment of urologic malignancies in the Philippines: A multi-center prospective cohort study (PUMA study)
Rudolfo I. De Guzman ; Bennie Dick C. Catangay ; Norwin T. Uy ; Hermenegildo Jose B. Zialcita ; Jose-vicente T. Prodigalidad
Philippine Journal of Urology 2025;35(2):88-96
OBJECTIVES
To create a pilot urologic malignancy registry using demographic and clinical data of a cohort of patients newly diagnosed to have urologic malignancies in the year 2021.
METHODSThis was a prospective cohort study conducted in four study sites: National Kidney and Transplant Institute, East Avenue Medical Center, UP-Philippine General Hospital and Batangas Medical Center
RESULTSA total of 243 patients with newly diagnosed urologic cancers were enrolled. The median age was 61 years, with a wide range of 1 to 87 years. Most of the patients (81.47%) were male, while there were 45 females (18.52%) who had either urinary bladder, kidney or upper urothelial cancer. The most common type of malignancy was prostate cancer (34.57%), followed by kidney cancer (30.04%) and urinary bladder cancer (24.69%), consistent with the currently observed worldwide incidence. There were also 3 patients (1.23%) noted with multiple primaries. More than half of the patients (63.37%) received surgery as active treatment. After the two-year follow-up period, thirteen patients (5.35%) developed progressive disease, and 14 patients (5.76%) died.
CONCLUSIONThis urologic cancer registry represents the first multi-center, investigator-initiated epidemiologic study of its kind in the Philippines. As a proof-of-concept (POC) project, it demonstrates the feasibility of establishing a national database capturing baseline data on the country’s most common urologic malignancies.
Cohort Studies ; Multiple Chronic Conditions ; Prostatic Neoplasms ; General Surgery ; Epidemiology
9.The use of artificial intelligence machine learning models to predict stone-free status after percutaneous nephrolithotomy: A meta-analysis
Rajiv H. Kalbit ; Enrique Ian S. Lorenzo ; Karl Marvin M. Tan
Philippine Journal of Urology 2025;35(2):97-106
OBJECTIVE
This meta-analysis aimed to evaluate the diagnostic capability of machine learning (ML) models in predicting stone-free status following percutaneous nephrolithotomy (PCNL).
METHODSA comprehensive literature search was conducted across MEDLINE, Embase, Scopus, Cochrane, Google Scholar and supplementary databases was undertaken until June 2023. Inclusion criteria were English publications assessing the sensitivity and specificity of ML in predicting post PCNL stone-free status. Studies on non-human subjects or with incomplete data sets were excluded. Quality assessment utilized the Cochrane Risk of Bias Tool. Pooled sensitivity, specificity, and other diagnostic metrics were calculated using Meta-Disc 1.4 software.
RESULTSOf the 65 initial articles, 5 met the inclusion criteria, representing a total of 1,773 participants. The accuracy of ML models ranged from 44% to 94.8%. The pooled sensitivity and specificity were 0.60 (95% CI [0.57, 0.63]) and 0.87 (95% CI [0.84, 0.89]), respectively. The pooled positive likelihood ratio was 4.69 (95% CI [3.82, 5.77]) and the negative likelihood ratio was 0.45 (95% CI [0.41, 0.48]). The diagnostic odds ratio was 10.93 (95% CI [8.35, 14.33]). The area under the curve (AUC) stood at 0.9372, signifying an excellent diagnostic performance.
CONCLUSIONMachine learning models demonstrate significant potential in accurately predicting stone-free status post-PCNL. However, the small number of included studies, retrospective designs, and heterogeneity in ML approaches limit generalizability. Standardized definitions, larger multicenter datasets, and prospective validation are required before routine clinical adoption.
Human ; Male ; Female ; Meta-analysis ; Artificial Intelligence ; Machine Learning ; Nephrolithotomy, Percutaneous
10.Concomitant bilateral nephrolithiases, high-grade muscle invasive urothelial cancer, and renal mass: What would you do?
Kristine Antonette Po ; Rudolfo I. De Guzman
Philippine Journal of Urology 2025;35(2):107-111
This paper discusses the diagnostic and therapeutic approach to a patient with concomittant serious clinical conditions such as bilateral nephrolithiasis, and possible dual primary malignancies of the kidney and the urinary bladder.
A 62-year-old male presented with gross hematuria. Radiographic imaging revealed a large urinary bladder mass, bilateral hydronephrosis due to obstructive nephrolithiases, and a left solid renal mass. After appropriate cardiopulmonary optimization, the authors opted to do a preliminary transurethral resection of the bladder tumor. This was followed by staged therapies with right ultrasound-guided PCNL; a left partial nephrectomy with nephrolithotomy, and radical cystectomy with ileal conduit. Unfortunately, the patient did not survive the multiple surgeries and expired. The chronology of the various therapeutic procedures in cases of synchronous serious clinical conditions of the urinary tract such as nephrolithiasis, renal and bladder neoplasms need to be individualized and will dictate the outcome of the entire therapy.
Human ; Male ; Nephrolithiasis ; Xanthogranulomatous ; Pyelonephritis ; Muscle-invasive Urothelial ; Carcinoma

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