Objective: To explore the intervention effects of different exercise modalities on executive function in school aged children, providing references for formulating exercise prescriptions to promote school aged children executive function. Methods: A systematic literature search was conducted using PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, VIP and CBM to identify studies on the effects of exercises on executive function in school aged children. The search period spanned from the database inception to August 2025. Two researchers independently screened the literature, extracted data, and evaluated the risk of bias of the included studies. Network Meta analysis was performed using Stata 16.0. Results: A total of 51 studies involving 5 710 school aged children and seven modalities of exercises(control group,small ball sports,large ball sports,aerobic exercise,combined exercise,sport game,gymnastic and dance sports) were finally included. Network Meta analysis showed that, in terms of inhibitory control development of school aged children, small ball sports ( SMD =-0.98,95% CI =-1.32 to -0.64 ), large ball sports ( SMD =-0.64,95% CI =-0.91 to -0.36), and mixed sports ( SMD =-0.26,95% CI =-0.50 to -0.02]) were more effective than the control group; in terms of working memory, largeball sports ( SMD =-1.26,95% CI =-1.88 to -0.65) and small ball sports ( SMD =-0.91,95% CI =-1.64 to -0.19) were superior to the control group; in terms of improving cognitive flexibility, large ball sports ( SMD =-1.02,95% CI =-1.28 to -0.76), gymnastics and dance sports ( SMD =-0.80,95% CI =-1.21 to -0.40), and small ball sports ( SMD =-0.75,95% CI =-1.15 to -0.36) were more effective than the control group (all P <0.05). Surface under cumulative ranking curve(SUCRA) showed that small ball sports had the highest value (SUCRA=98.9%) in improving inhibitory control, while large ball sports achieved the highest score(SUCRA=92.6%) in enhancing working memory, and large ball sports also had the highest value(SUCRA=94.7%) in promoting cognitive flexibility. Conclusions For developing inhibitory control in school aged children, small ball sports are recommended as a priority. For enhancing working memory and cognitive flexibility, large ball sports are recommended.

Objective To investigate the correlation between chemoradiotherapy sensitivity and serum microRNA(miR)levels in the patients with intermediate and advanced cervical cancer.Methods Totally 112 patients with intermediate and advanced cervical cancer admitted to Nanchong Central Hospital from January 2020 to March 2022 were included in the study.All the patients were treated with synchronous radiochemotherapy.The sensitivity of the patients to the treatment regimen was analyzed,and the patients were divided into high sensitivity group(n=68)and low sensitivity group(n=44)in accordance with the sensitivity of the patients.The expression levels of serum miR-136,miR-664 and miR-206 in all patients were detected by real-time fluorescent quantitative PCR,and their expression levels were compared between the high sensitivity group and the low sensitivity group.The value of assessing the sensitivity to radiochemotherapy was evaluated by analyzing the expression levels of miR-136,miR-664 and miR-206 by receiver operating characteristic(ROC)curve.The relationship between radiochemotherapy sensitivity and clinical pathological features was analyzed,and influencing factors affecting sensitivity were explored in the patients with intermediate and advanced cervical cancer.Results The expression levels of miR-136 and miR-664 in the high sensitivity group were significantly higher than those in the low sensitivity group(P<0.05),and the expression level of miR-206 was significantly lower than that in the low sensitivity group(P<0.05).ROC curve results showed that serum miR-136,miR-664 and miR-206 all displayed a certain evaluation value for sensitivity of the patients,and the areas under the curve were 0.834,0.910 and 0.855,respectively.There was statistical significance in International Federation of Gynecology and Obstetrics(FIGO)staging when comparisons were made between the two groups(P<0.05).Multivariate Logistic regression analysis revealed that miR-136,miR-664,miR-206 and FIGO staging were all independent influencing factors of radiochemotherapy sensitivity in the patients with intermediate and advanced cervical cancer(P<0.05).Conclusion The expression levels of miR-136,miR-664 and miR-206 were correlated with the radiochemotherapy sensitivity of the patients with cervical cancer.The down-regulation of miR-136,miR-664 and the up-regulation of miR-206 might indicate radiochemotherapy resistance of cervical cancer.