1.Super-selective arterial embolization for the treatment of abdominal wall hematoma
Lele YAN ; Jie JI ; Yuan MA ; Zizhuo LIU ; Penghua LV
Journal of Interventional Radiology 2025;34(2):165-169
Objective To investigate the safety and efficacy of super-selective arterial embolization in the treatment of abdominal wall hematoma.Methods The clinical data of 11 patients with abdominal wall hematoma,who were admitted to the Northern Jiangsu People's Hospital of China from January 2018 to December 2023,were retrospectively analyzed.All patients received angiography together with super-selective arterial embolization.The effectiveness of embolization treatment was evaluated by the technical success rate and therapeutic effect,and the safety was evaluated by the incidence of complication.Results The median age of the 11 patients was 70 years,91%were female,with a body mass index(BMI)of 25.1 kg/m2,subcutaneous fat thickness of 2.8 cm,and international normalized ratio(INR)of 1.12.DSA showed that 8 patients(72%)had active bleeding signs,3 patients(28%)had no active bleeding signs.Under DSA,a total of 18 responsible vessels,including 6 lumbar arteries(33.3%),5 deep circumflex iliac arteries(27.7%),5 inferior epigastric arteries(27.7%)and 2 iliolumbar arteries(11.3%),were identified and were treated with embolization.The median time spent for operation was 80 minutes.The technical success rate was 100%and the clinical effective rate was 91%.No operation-related major complications occurred,and the median hospital stay was 6 days.Conclusion For the abdominal wall hematoma in aged,obesity patients with underlying diseases,super-selective arterial embolization is a therapeutic method with high technical success rate,high clinical effective rate and satisfactory clinical safety.
2.Microwave ablation or radiofrequency ablation combined with bone cement augmentation and simple bone cement augmentation for vertebral metastatic tumors
Fu'an WANG ; Jie JI ; Yuan MA ; Wenjie ZHOU ; Bo YAN ; Penghua LV
Journal of Interventional Radiology 2025;34(3):268-271
Objective To discuss the clinical efficacy of microwave ablation(MWA)combined with percutaneous vertebroplasty(PVP),radiofrequency ablation(RFA)combined with PVP,and simple PVP in the treatment of vertebral metastatic tumors.Methods A total of 65 patients with vertebral metastatic tumors,who were admitted to the Northern Jiangsu People's Hospital of China to receive treatment from January 2019 to June 2023,were enrolled in this study.The patients were divided into MWA plus PVP group(M+P group,n=25,27 diseased vertebral bodies in total),RFA plus PVP group(R+P group,n=20,23 diseased vertebral bodies in total),and simple PVP group(P group,n=20,24 diseased vertebral bodies in total).Visual analog scale(VAS)score was used to assess the preoperative pain degree and the postoperative relief degree.Bone cement distribution and leakage at one week after surgery were evaluated.Results Successful operation was accomplished in all of the patients.No serious procedure-related complications occurred in all the patients of three groups.In R+P group,P group and M+P group,the preoperative mean VAS scores were(8.48±0.80)points,(8.57±0.98)points and(8.20±1.00)points respectively;the differences among the three groups were not statistically significant(P>0.05).One week after operation,the pain was significantly relieved in all the patients of three groups;the mean VAS scores in R+P group,P group and M+P group were(4.10±0.85)points,(3.17±0.93)points and(2.44±1.23)points respectively,and the reduction in VAS score was most pronounced in M+P group(P<0.05).Six months after operation;the mean VAS scores in R+P group,P group and M+P group were(1.87±0.84)points,(4.60±1.09)points and(1.48±0.71)points respectively;and the reduction in VAS score was most pronounced in the M+P group(P<0.05).The used amount of bone cement in M+P group,R+P group and P group was(7.54±1.44)mL,(5.48±1.12)mL and(4.59±1.56)mL respectively,the difference among the three groups was statistically significant(P<0.05).The vascular leakage rate(34.8%)and non-vascular leakage rate(52.2%)in P group were remarkably higher than those in R+P group and in M+P group(P<0.05).No statistically significant difference in the rate of cement leakage existed between R+P group and M+P group(P>0.05).Conclusion For the treatment of vertebral metastases,MW A plus PVP is superior to RFA plus PVP in pain relief rate.
3.Predictive factors of poor prognosis in patients with acute basilar artery occlusion who got first-pass effect after mechanical thrombectomy
Yun DING ; Yuan MA ; Penghua LYU ; Peicheng LI ; Bo LI ; Chen YUAN ; Wanci LI ; Dianyi GU ; Long CHEN
Chinese Journal of Interventional Imaging and Therapy 2025;22(2):81-85
Objective To observe the predictive factors of poor prognosis in patients with acute basilar artery occlusion(BAO)who got first-pass effect(FPE)after mechanical thrombectomy(MT).Methods Eighty-two acute BAO patients who got FPE following MT were retrospectively collected and divided into good prognosis group(modified Rankin scale[mRS]score≤3,n=48)and poor prognosis group(mRS score>3,n=34)90 days after treatments.The data were compared between groups,and variables which showed P<0.1 were included in multivariate logistic regression analysis to identify independent predictors of poor prognosis in acute BAO patients who got FPE after MT.Results Higher age of patients,pre-treatment National Institute Health stroke scale(NIHSS)and neutrophil-to-lymphocyte ratio(NLR),also higher proportions of patients with diabetes mellitus,atrial fibrillation(AF)and cardioembolic stroke in trial of org 10 172 in acute stroke treatment(TOAST)classification were found in poor prognosis group than those in good prognosis group(all P<0.05).Conversely,patients in poor prognosis group had lower pre-treatment Glasgow coma scale(GCS)scores,lower posterior circulation-Alberta stroke program early CT score(pc-ASPECTS)and basilar artery on CT angiography(BATMAN)scores(all P<0.05).Multivariate logistic regression analysis revealed patients complicated with AF(OR[95%CI]=29.769[1.470,602.943])and elevated pre-treatment NLR(OR[95%CI]=1.212[1.016,1.446])had relatively poor prognosis(both P<0.05),whereas those with increased pre-treatment GCS score(OR[95%CI]=0.615[0.429,0.882]),elevated pc-ASPECTS(OR[95%CI]=0.263[0.092,0.748])and higher BATMAN score(OR[95%CI]=0.260[0.085,0.796])had relatively better prognosis(all P<0.05).Conclusion Complicated with AF,low pre-treatment GCS score,high NLR,low pc-ASPECTS and low BATMAN score were all predictive factors for poor prognosis in acute BAO patients who got FPE after MT.
4.Early- and mid-term outcomes of using porous-coated metaphyseal sleeves to reconstruct severe bone defects in revision total knee arthroplasty
Penghua MA ; Tingxian LING ; Fuxing PEI ; Jing YANG ; Pengde KANG ; Bin SHEN ; Zongke ZHOU
Chinese Journal of Orthopaedic Trauma 2025;27(6):479-484
Objective:To explore the early- to mid-term therapeutic efficacy of using porous-coated metaphyseal sleeves to reconstruct severe bone defects in revision total knee arthroplasty (rTKA).Methods:A retrospective analysis was conducted of the clinical data of the 39 patients (40 knees) who had undergone rTKA by porous-coated metaphyseal sleeve reconstruction at Department of Orthopaedics, West China Hospital, Sichuan University between May 2017 and September 2023. The cohort included 6 males (6 knees) and 33 females (34 knees), with an age of (67.0±9.7) years. The revision was to cure periprosthetic infection after TKA in 12 knees, to correct prosthesis loosening in 19 knees, to treat periprosthetic fracture in 4 knees, to stabilize postoperative joint instability in 4 knees, and to manage postoperative joint stiffness in 1 knee. All patients underwent standard revision procedures, including removal of the original prosthesis, management of bone defects, implantation of revision prosthesis, and adjustment of ligamentous balance and fixation. The patients' surgical time, intraoperative blood loss, incidence of complications, as well as visual analogue scale (VAS), knee range of motion, and Hospital for Special Surgery (HSS) knee joint scores at the last follow-up were recorded.Results:The surgical time was (2.7±0.8) hours, and intraoperative blood loss (337.5±165.4) mL for this cohort. All the 39 patients were followed up for (4.8±2.1) years after surgery. At the last follow-up, their VAS pain score was 2.0 (1.0, 2.0) points, their knee range of motion reached 116.3°±12.2°, and their total score, pain score, and function score of the HSS system were respectively 87.0 (82.8, 89.3) points, 25.0 (22.8, 29.0) points, and 61.0 (60.0, 62.0) points, all showing statistically significant improvements compared with their preoperative values [(6.8±1.7) points, 70.4°±15.2°, (43.1±9.6) points, (9.3±3.1) points, and (33.8±10.1) points] ( P<0.05). In all patients, incisions healed at one stage after surgery, and no complications such as deep vein thrombosis or neurovascular injury occurred. Complications included popliteal artery thrombosis in 1 patient (1 knee) immediately after surgery, acute infection in 1 patient (1 knee) at 3 years after surgery, and periprosthetic fracture due to a traffic accident in 1 patient (1 knee) at 4 years after surgery, and distal prosthesis-related pain in 3 patients (3 knees). Conclusion:Use of porous-coated metaphyseal sleeves in rTKA to reconstruct severe bone defects exhibits favorable early- to mid-term therapeutic outcomes.
5.Predictive factors of poor prognosis in patients with acute basilar artery occlusion who got first-pass effect after mechanical thrombectomy
Yun DING ; Yuan MA ; Penghua LYU ; Peicheng LI ; Bo LI ; Chen YUAN ; Wanci LI ; Dianyi GU ; Long CHEN
Chinese Journal of Interventional Imaging and Therapy 2025;22(2):81-85
Objective To observe the predictive factors of poor prognosis in patients with acute basilar artery occlusion(BAO)who got first-pass effect(FPE)after mechanical thrombectomy(MT).Methods Eighty-two acute BAO patients who got FPE following MT were retrospectively collected and divided into good prognosis group(modified Rankin scale[mRS]score≤3,n=48)and poor prognosis group(mRS score>3,n=34)90 days after treatments.The data were compared between groups,and variables which showed P<0.1 were included in multivariate logistic regression analysis to identify independent predictors of poor prognosis in acute BAO patients who got FPE after MT.Results Higher age of patients,pre-treatment National Institute Health stroke scale(NIHSS)and neutrophil-to-lymphocyte ratio(NLR),also higher proportions of patients with diabetes mellitus,atrial fibrillation(AF)and cardioembolic stroke in trial of org 10 172 in acute stroke treatment(TOAST)classification were found in poor prognosis group than those in good prognosis group(all P<0.05).Conversely,patients in poor prognosis group had lower pre-treatment Glasgow coma scale(GCS)scores,lower posterior circulation-Alberta stroke program early CT score(pc-ASPECTS)and basilar artery on CT angiography(BATMAN)scores(all P<0.05).Multivariate logistic regression analysis revealed patients complicated with AF(OR[95%CI]=29.769[1.470,602.943])and elevated pre-treatment NLR(OR[95%CI]=1.212[1.016,1.446])had relatively poor prognosis(both P<0.05),whereas those with increased pre-treatment GCS score(OR[95%CI]=0.615[0.429,0.882]),elevated pc-ASPECTS(OR[95%CI]=0.263[0.092,0.748])and higher BATMAN score(OR[95%CI]=0.260[0.085,0.796])had relatively better prognosis(all P<0.05).Conclusion Complicated with AF,low pre-treatment GCS score,high NLR,low pc-ASPECTS and low BATMAN score were all predictive factors for poor prognosis in acute BAO patients who got FPE after MT.
6.Early- and mid-term outcomes of using porous-coated metaphyseal sleeves to reconstruct severe bone defects in revision total knee arthroplasty
Penghua MA ; Tingxian LING ; Fuxing PEI ; Jing YANG ; Pengde KANG ; Bin SHEN ; Zongke ZHOU
Chinese Journal of Orthopaedic Trauma 2025;27(6):479-484
Objective:To explore the early- to mid-term therapeutic efficacy of using porous-coated metaphyseal sleeves to reconstruct severe bone defects in revision total knee arthroplasty (rTKA).Methods:A retrospective analysis was conducted of the clinical data of the 39 patients (40 knees) who had undergone rTKA by porous-coated metaphyseal sleeve reconstruction at Department of Orthopaedics, West China Hospital, Sichuan University between May 2017 and September 2023. The cohort included 6 males (6 knees) and 33 females (34 knees), with an age of (67.0±9.7) years. The revision was to cure periprosthetic infection after TKA in 12 knees, to correct prosthesis loosening in 19 knees, to treat periprosthetic fracture in 4 knees, to stabilize postoperative joint instability in 4 knees, and to manage postoperative joint stiffness in 1 knee. All patients underwent standard revision procedures, including removal of the original prosthesis, management of bone defects, implantation of revision prosthesis, and adjustment of ligamentous balance and fixation. The patients' surgical time, intraoperative blood loss, incidence of complications, as well as visual analogue scale (VAS), knee range of motion, and Hospital for Special Surgery (HSS) knee joint scores at the last follow-up were recorded.Results:The surgical time was (2.7±0.8) hours, and intraoperative blood loss (337.5±165.4) mL for this cohort. All the 39 patients were followed up for (4.8±2.1) years after surgery. At the last follow-up, their VAS pain score was 2.0 (1.0, 2.0) points, their knee range of motion reached 116.3°±12.2°, and their total score, pain score, and function score of the HSS system were respectively 87.0 (82.8, 89.3) points, 25.0 (22.8, 29.0) points, and 61.0 (60.0, 62.0) points, all showing statistically significant improvements compared with their preoperative values [(6.8±1.7) points, 70.4°±15.2°, (43.1±9.6) points, (9.3±3.1) points, and (33.8±10.1) points] ( P<0.05). In all patients, incisions healed at one stage after surgery, and no complications such as deep vein thrombosis or neurovascular injury occurred. Complications included popliteal artery thrombosis in 1 patient (1 knee) immediately after surgery, acute infection in 1 patient (1 knee) at 3 years after surgery, and periprosthetic fracture due to a traffic accident in 1 patient (1 knee) at 4 years after surgery, and distal prosthesis-related pain in 3 patients (3 knees). Conclusion:Use of porous-coated metaphyseal sleeves in rTKA to reconstruct severe bone defects exhibits favorable early- to mid-term therapeutic outcomes.
7.Assessment of axillary lymph node metastasis in breast cancer by multimodal MRI
Jing XU ; Guanghui MA ; Penghua LIU
China Medical Equipment 2024;21(5):64-68
Objective:To analyze the assessment effect and reliable indicators of multimodal magnetic resonance imaging(MRI)for axillary lymph node metastasis(ALNM)of breast cancer.Methods:A total of 152 female patients with breast cancer who were diagnosed and received surgical treatment in Handan First Hospital from January 2020 to November 2021 were selected.According to the pathological results of postoperative axillary lymph node,45 cases with ALNM were selected as ALNM group,and 107 cases without ALNM were selected as non-ALNM group.Dynamic contrast enhanced-magnetic resonance imaging(DCE-MRI),T2weighted image(T2WI)and diffusion-weighted imaging(DWI)were used to determine breast cancer ALNM.Results:The diagnostic sensitivity,specificity,positive predictive value and negative predictive value and diagnostic consistent rate of multimodal MRI were respectively 82.22%,96.26%,90.24%,92.79%and 92.11%.Logistic regression analysis showed that the maximum tumor size and ADC value were closely correlated with lymph node metastasis.The receiver operating characteristic(ROC)curve analysis showed that the area under curve(AUC)of the maximum tumor diameter was 0.797(95%CI=0.694~0.842,P<0.01),and the diagnostic sensitivity and specificity were respectively 77.4%and 60.7%when the optimal cut-off value was 1.96cm.The AUC of ADC value was 0.844(95%CI=0.808-0.915,P<0.01),and the diagnostic sensitivity and specificity were respectively 82.1%and 71.2%when the optimal cutoff value was 1.122×10-3mm2/s.The AUC value of the combined diagnosis of maximum tumor diameter and AUC value was 0.952(95%CI:0.904-0.991,P<0.01),and the sensitivity and specificity were respectively 88.6%and 81.4%under the optimal cutoff value.The AUC value of the combined indicators was higher than that of the maximum tumor diameter(Z=3.982,P<0.05)and ADC value(Z=3.014,P<0.05),respectively.Conclusion:Multimodal MRI has a good diagnostic effect on breast cancer ALNM,in which the maximum tumor diameter and AUC value are important reference indicators,and the combination of them can improve the diagnostic efficiency.

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