1.Bronchial arterial chemoembolization combined with microwave ablation and immunotherapy for the treatment of advanced lung squamous cell carcinoma:a clinical study
Bo YAN ; Penghua LV ; Fuan WANG ; Shuxiang WANG ; Ling SUN
Journal of Interventional Radiology 2025;34(1):64-69
Objective To investigate the clinical effect and safety of bronchial arterial chemoembolization(BACE)combined with micro wave ablation(MW A)and immunotherapy in treating patients with advanced lung squamous cell carcinoma.Methods The clinical data of 68 patients with advanced lung squamous cell carcinoma,who were admitted to the North Jiangsu People's Hospital of China from June 2020 to June 2022 to receive treatment,were retrospectively analyzed.According to the therapeutic method,the patients were divided into control group(n=30,receiving BACE combined with immunotherapy)and observation group(n=38,receiving BACE followed by MW A,which was performed with CT-guided localization of the lung lesion,and immunotherapy in 3-5 days after BACE).Results The surgical success rate in both the 30 patients of the observation group and the 38 patients of the control group was 100%.After treatment,no surgery-related or chemoembolization-related serious complications occurred in both groups.In the control group and the observation group,the mean progression-free survival(PFS)was(5.70±1.61)months and(12.10±0.72)months respectively,the mean overall survival(OS)was(11.80±1.10)months and(13.00±1.13)months respectively.The PFS of the observation group was obviously longer than that of the control group(P<0.05),and no statistically significant difference in OS existed between the two groups(P=0.255).Conclusion BACE combined with MW A and immunotherapy can effectively control the advanced lung squamous cell carcinoma,it has reliable short-term efficacy when compared with BACE plus immunotherapy,and it can inhibit tumor growth and prolong the PFS of patients,with a trend of extending OS and a satisfactory clinical safety.
2.Super-selective arterial embolization for the treatment of abdominal wall hematoma
Lele YAN ; Jie JI ; Yuan MA ; Zizhuo LIU ; Penghua LV
Journal of Interventional Radiology 2025;34(2):165-169
Objective To investigate the safety and efficacy of super-selective arterial embolization in the treatment of abdominal wall hematoma.Methods The clinical data of 11 patients with abdominal wall hematoma,who were admitted to the Northern Jiangsu People's Hospital of China from January 2018 to December 2023,were retrospectively analyzed.All patients received angiography together with super-selective arterial embolization.The effectiveness of embolization treatment was evaluated by the technical success rate and therapeutic effect,and the safety was evaluated by the incidence of complication.Results The median age of the 11 patients was 70 years,91%were female,with a body mass index(BMI)of 25.1 kg/m2,subcutaneous fat thickness of 2.8 cm,and international normalized ratio(INR)of 1.12.DSA showed that 8 patients(72%)had active bleeding signs,3 patients(28%)had no active bleeding signs.Under DSA,a total of 18 responsible vessels,including 6 lumbar arteries(33.3%),5 deep circumflex iliac arteries(27.7%),5 inferior epigastric arteries(27.7%)and 2 iliolumbar arteries(11.3%),were identified and were treated with embolization.The median time spent for operation was 80 minutes.The technical success rate was 100%and the clinical effective rate was 91%.No operation-related major complications occurred,and the median hospital stay was 6 days.Conclusion For the abdominal wall hematoma in aged,obesity patients with underlying diseases,super-selective arterial embolization is a therapeutic method with high technical success rate,high clinical effective rate and satisfactory clinical safety.
3.Microwave ablation or radiofrequency ablation combined with bone cement augmentation and simple bone cement augmentation for vertebral metastatic tumors
Fu'an WANG ; Jie JI ; Yuan MA ; Wenjie ZHOU ; Bo YAN ; Penghua LV
Journal of Interventional Radiology 2025;34(3):268-271
Objective To discuss the clinical efficacy of microwave ablation(MWA)combined with percutaneous vertebroplasty(PVP),radiofrequency ablation(RFA)combined with PVP,and simple PVP in the treatment of vertebral metastatic tumors.Methods A total of 65 patients with vertebral metastatic tumors,who were admitted to the Northern Jiangsu People's Hospital of China to receive treatment from January 2019 to June 2023,were enrolled in this study.The patients were divided into MWA plus PVP group(M+P group,n=25,27 diseased vertebral bodies in total),RFA plus PVP group(R+P group,n=20,23 diseased vertebral bodies in total),and simple PVP group(P group,n=20,24 diseased vertebral bodies in total).Visual analog scale(VAS)score was used to assess the preoperative pain degree and the postoperative relief degree.Bone cement distribution and leakage at one week after surgery were evaluated.Results Successful operation was accomplished in all of the patients.No serious procedure-related complications occurred in all the patients of three groups.In R+P group,P group and M+P group,the preoperative mean VAS scores were(8.48±0.80)points,(8.57±0.98)points and(8.20±1.00)points respectively;the differences among the three groups were not statistically significant(P>0.05).One week after operation,the pain was significantly relieved in all the patients of three groups;the mean VAS scores in R+P group,P group and M+P group were(4.10±0.85)points,(3.17±0.93)points and(2.44±1.23)points respectively,and the reduction in VAS score was most pronounced in M+P group(P<0.05).Six months after operation;the mean VAS scores in R+P group,P group and M+P group were(1.87±0.84)points,(4.60±1.09)points and(1.48±0.71)points respectively;and the reduction in VAS score was most pronounced in the M+P group(P<0.05).The used amount of bone cement in M+P group,R+P group and P group was(7.54±1.44)mL,(5.48±1.12)mL and(4.59±1.56)mL respectively,the difference among the three groups was statistically significant(P<0.05).The vascular leakage rate(34.8%)and non-vascular leakage rate(52.2%)in P group were remarkably higher than those in R+P group and in M+P group(P<0.05).No statistically significant difference in the rate of cement leakage existed between R+P group and M+P group(P>0.05).Conclusion For the treatment of vertebral metastases,MW A plus PVP is superior to RFA plus PVP in pain relief rate.
4.Nursing of interventional therapy for isolated superior mesenteric artery dissection
Suping GENG ; Lifu WANG ; Wennuo HUANG ; Mingyu CAI ; Penghua LV
Journal of Clinical Medicine in Practice 2014;(10):68-70
Objective To explore the nursing experience of interventional therapy forisolat-ed superior mesenteric artery dissection(ISMAD).Methods The clinical material of 12 patients with ISMAD was retrospectively analyzed.Preoperative preparation,close coordination with doc-tors and strict postoperative nursing were the key to the operation.Results All patients were suc-cessfully implanted the stent without complication.Conclusion Percutaneous endovascular stent implantation is a reliable treatment for ISMAD and it provides security for patients in perioprative period.
5.Nursing of interventional therapy for isolated superior mesenteric artery dissection
Suping GENG ; Lifu WANG ; Wennuo HUANG ; Mingyu CAI ; Penghua LV
Journal of Clinical Medicine in Practice 2014;(10):68-70
Objective To explore the nursing experience of interventional therapy forisolat-ed superior mesenteric artery dissection(ISMAD).Methods The clinical material of 12 patients with ISMAD was retrospectively analyzed.Preoperative preparation,close coordination with doc-tors and strict postoperative nursing were the key to the operation.Results All patients were suc-cessfully implanted the stent without complication.Conclusion Percutaneous endovascular stent implantation is a reliable treatment for ISMAD and it provides security for patients in perioprative period.

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