1.Application of cell transplantation technology in the repair of spinal cord injury: a review
Chinese Journal of Trauma 2024;40(10):947-954
Spinal cord injury is a serious disease of the central nervous system characterized by high disability and mortality, and shows an increasing incidence over year. Traditional treatment methods include surgery, medication and rehabilitation therapy, but the therapeutic outcomes are generally unsatisfactory and the functional recovery of patients is very limited. In recent years, cell transplantation technology, with a role in promoting neuron regeneration and neural pathway reconstruction by transplanting exogenous cells to the injured site, has become a promising treatment strategy for spinal cord injury. However, at present, cell transplantation technology is still faced with problems such as the diversified transplanted cell types, poor survival rate of transplanted cells, and uncertainty in the timing and dosage of transplantation in the repair of spinal cord injury. To this end, the authors reviewed the research progress in the application of cell transplantation technology in the repair of spinal cord injury, aiming to provide a reference for the clinical treatment.
2.Evaluation of therapeutic efficacy of radiofrequency ablation on hepatic cancer: a preliminary study using superb microvascular imaging
Zipeng HE ; Hua TANG ; Pengcheng JIANG ; Hongyan ZHAO ; Shuying DONG
Chinese Journal of Hepatobiliary Surgery 2021;27(9):663-666
Objective:To study the predictive value of superb microvascular imaging(SMI) in evaluating therapeutic efficacy of hepatic cancer treated by percutaneous radiofrequency ablation(PRFA).Methods:From Feb 2017 to Feb 2018, 55 patients (male: 31, female: 24, age range: 37-68 years, mean age: 56years) with 72 hepatic carcinoma lesions (length: 21.3-45.6 mm, average: 31.2 mm) were detected by SMI and contrast-enhanced CT(CECT)before PRFA. One month after treatment, more than two imaging examinations (CECT, CEMR, ultrasonic imaging) were used as the "gold standard" to evaluate the complete ablation rates. Consistency between the SMI grading and the arterial phase enhancement of CECT was analyzed by the Kappa-test.Results:Before PRFA, SMI showed 12 lesions (16.7%) to be in grade Ⅰ, 28 lesions (38.9%) in grade Ⅱ and 32 lesions (44.4%) in grade Ⅲ. The arterial phase of CECT showed 37 lesions (51.4%) to have no obvious enhancement and 35 lesions (48.6%) to have obvious enhancement. Consistency analysis showed that there was a high consistency between SMI and CECT(Kappa=0.861, P<0.001). The higher the SMI grading, the more obvious the enhancement on CECT. The complete ablation rates of the grade Ⅰ, grade Ⅱ and grade Ⅲ lesions were 100%(12/12), 92.9%(26/28) and 71.9%(23/32), respectively. The complete ablation rate of the lesions in grade Ⅲ was significantly lower than that in grade Ⅰ and grade Ⅱ (both P<0.05). Conclusion:SMI showed a good consistency with CECT in evaluating the blood flow signals of hepatic cancer, SMI grading could be used in predicting the therapeutic efficacy of hepatic cancer treated by PRFA.
3.Smoking epidemiology among primary and middle school students in Beijing during 2005-2015
GUO Xin, ZHANG Pengcheng, XU Wenjie, XIA Zhiwei,HUA Chenxi,BAI Chengxu.
Chinese Journal of School Health 2019;40(1):65-68
Objective:
To understand the changes of smoking behavior among primary and middle school students in Beijing during 2005-2015.
Methods:
The primary and middle schools in Beijing were classified and then taken as a sampling frame. Twophase stratified random cluster sampling was conducted with school as primary sampling unit (PSU) and class as the minimum sampling unit, respectively. Beijing Schoolbased Smoking Monitoring Questionnaire was surveyed in 2005 and 2005, 2010, 2011, 2013 and 2015 anonymously.
Results:
In 2015, the smoking rate among primary and middle school students in Beijing was 9.41%. Among them, for primary, junior, high school and vocational high school students, the rates were 7.05%, 7.06%, 12.41% and 34.11%, respectively. The smoking rates were now 3.26%, with 1.99%, 1.80%, 3.48% and 20.22%, respectively, among primary, middle and high school and vocational high school students. male, vocational school students were more likely to report smoking across six waves of surveillance. Results from the surveillance in 2015 showed a decreasing trend in ever smoking rate and current smoking rate compared with previous survey. About half of the current student smokers were reported to take 1 cigarette/day, and about 10% smokers were reported to take 10 cigarettes/day. Students were most likely to smoke at home(24.02%), followed by smoking at schools(12.74%). The percentage of buying cigarettes by themselves was increased from 17.10% in 2008 to 66.09% in 2015.
Conclusion
From 2005 to 2015, both ever smoking and current smoking rate among middle school students in Beijing decreased in general, however smoking among vocational high school students warrants further attention.
5.Electrospinning technology in tissue engineering scaffolds.
Haoyi LI ; Yong LIU ; Xuetao HE ; Yumei DING ; Hua YAN ; Pengcheng XIE ; Weimin YANG
Chinese Journal of Biotechnology 2012;28(1):15-25
Tissue engineering technology provides a new method to repair ill tissue and worn-out organs. In tissue engineering, scaffolds play an important role in supporting cell growth, inducing tissue regeneration, controlling tissue structure and releasing active factor. In the last decade, electrospinning technology developed rapidly and opened vast application fields for scaffolds. In this review, we summarized the technological conditions of electrospinning for scaffolds, the study of electrospun fiber scaffolds applied in tissue cell cultivation, and some new directions of electrospinning technology for scaffolds. We also addressed development directions of electrospinning research for scaffolds.
Absorbable Implants
;
Biocompatible Materials
;
chemistry
;
Electrochemistry
;
methods
;
Guided Tissue Regeneration
;
Tissue Engineering
;
instrumentation
;
methods
;
Tissue Scaffolds
;
chemistry


Result Analysis
Print
Save
E-mail