ObjectiveTo evaluate the public health governance capacity in Jiangsu Province and provide an optimized pathway for the construction of a “strong, rich, beautiful, and high-quality” new Jiangsu. MethodsA total of 806 policy documents, 658 public information reports, and 148 research literatures related to public health governance capacity in Jiangsu Province from January 1995 to December 2023 were collected. The status of current public health goverance was assessed based on the evaluation criteria suitable for public health systems, and the strengths and the weaknesses of the system were identified. ResultsThe public health governance capability of Jiangsu Province was scored at 738.3 points, ranking 3rd nationally. Maternal health care and emergency response capacities achieved leading positions nationwide, both ranking 2nd. Jiangsu had exhibited a standardized guidance in the strategic level, a well-established management mechanism, an extensive coverage in information collection, and a scientifically established health targets setting. However, bottlenecks remained, including an unclear division of responsibilities across organizational departments, an insufficient public-health workforce, the absence of a stable growth mechanism for government funding investment, and difficulties in promptly identifying public needs. ConclusionJiangsu’s public-health system demonstrates leading nationally, yet several components remain underdeveloped. Future efforts should consolidate advantages while addressing weaknesses, further diversify content and forms, establish a stable funding increase mechanism, and clarify departmental functions, thereby providing solid health support for realizing the developmental goals of a “strong, rich, beautiful and high-quality” new Jiangsu.

Objective:To observe the pregnancy outcomes of patients with unexplained recurrent spontaneous abortion (URSA) after interventional treatment or expectant treatment.Methods:This prospective study followed up 398 patients with recurrent spontaneous abortion from March 2017 to September 2022 in seven hospitals. Among them, 267 patients were diagnosed with URSA, including 124 patients who were initially diagnosed in the interventional treatment hospital and 143 patients who were initially diagnosed in the expectant treatment hospital. All URSA patients were followed up for 33 months. Ongoing pregnancy rates were observed as main outcome indicators.Results:A total of 127 patients became pregnant, and 107 of them had sustained pregnancies, the ongoing pregnancy rate was 84.25% (107/127). The ongoing pregnancy rate was 86.11% (31/36) in the interventional treatment group and 83.52% (76/91) in the expectant treatment group, with no significant difference ( P>0.05). During the follow-up, the ongoing pregnancy rates in the interventional treatment hospital and the expectant treatment hospital were 75.71% (53/70) and 94.74% (54/57), respectively, with a significant difference ( P<0.05). The ongoing pregnancy rate after interventional treatment in the interventional treatment hospital was 82.76% (24/29), which was similar to the 94.00% (47/50) after expectant treatment in the expectant treatment hospital ( P>0.05). Conclusion:The ongoing pregnancy rate of interventional treatment for URSA patients has not been significantly improved, suggesting that it may not be necessary to carry out this treatment.

Objective:To observe the pregnancy outcomes of patients with unexplained recurrent spontaneous abortion (URSA) after interventional treatment or expectant treatment.Methods:This prospective study followed up 398 patients with recurrent spontaneous abortion from March 2017 to September 2022 in seven hospitals. Among them, 267 patients were diagnosed with URSA, including 124 patients who were initially diagnosed in the interventional treatment hospital and 143 patients who were initially diagnosed in the expectant treatment hospital. All URSA patients were followed up for 33 months. Ongoing pregnancy rates were observed as main outcome indicators.Results:A total of 127 patients became pregnant, and 107 of them had sustained pregnancies, the ongoing pregnancy rate was 84.25% (107/127). The ongoing pregnancy rate was 86.11% (31/36) in the interventional treatment group and 83.52% (76/91) in the expectant treatment group, with no significant difference ( P>0.05). During the follow-up, the ongoing pregnancy rates in the interventional treatment hospital and the expectant treatment hospital were 75.71% (53/70) and 94.74% (54/57), respectively, with a significant difference ( P<0.05). The ongoing pregnancy rate after interventional treatment in the interventional treatment hospital was 82.76% (24/29), which was similar to the 94.00% (47/50) after expectant treatment in the expectant treatment hospital ( P>0.05). Conclusion:The ongoing pregnancy rate of interventional treatment for URSA patients has not been significantly improved, suggesting that it may not be necessary to carry out this treatment.

Objective:To explore the relationship between integrin ɑ3(ITGA3)expression and immune cell infiltration in colorectal cancer(CRC).Methods:Bioinformatic methods were used to analyze ITGA3 mRNA expression in pan-cancer and CRC tissues,as well as its associ-ation with CRC prognosis.The correlation between ITGA3 and tumor-infiltrating immune cells was also investigated.In total,233 cases of CRC diagnosed at Shanxi Provincial Cancer Hospital between January and December 2021 were included,and ITGA3,CD8,CD163,FOXP3,PD-L1,CTLA-4,and PD-1 expression in CRC tissues were determined by immunohistochemistry(IHC)to analyze the relationship between ITGA3 and infiltrating immune cells and immune checkpoints.Results:Bioinformatics analysis showed elevated ITGA3 mRNA levels in CRC.High ITGA3 expression was associated with PFS(P＜0.05).Univariate and multifactorial analyses showed that age and stage were significantly cor-related with prognosis(P＜0.05).In addition,ITGA3 upregulation was closely correlated with multiple immune cell infiltration levels in CRC.Furthermore,IHC results showed that ITGA3 expression in CRC tissues was significantly higher than that in adjacent normal tissues(P＜0.05).ITGA3 expression was associated with lymph node metastasis(P＜0.05)and correlated with the expression of immune markers,such as CD8+T-cells,PD-L1,and CTLA-4(P＜0.05).Conclusions:ITGA3 is highly expressed in CRC,which is closely related to immune cell infiltration and may regulate the tumor immune microenvironment,which provides a new idea for clinical treatment and a potential new independent predictive marker.

To summarize the reform measures of nursing vertical management in our hospital under the background of diagnosis related groups,including refined performance management,cancellation of nursing main pharmacy classes,implementation of attending nursing working group,establishment of DRGs nursing quality control coder position,head nurse responsible for bed allocation,deepening nursing quality management and other measures,so as to provide references for other hospitals to carry out the reform of nursing vertical management under the background of DRGs.

Objective: To investigate and analyze the drinking water quality among rural primary and secondary schools in Guanzhong area in 2018, and to provide a basis for the targeted improvement of water supply facilities. Methods: Develop a questionnaire on the basic situation of centralized water supply in rural schools, according to the Standard Test Method for Drinking Water (GB/T 5750—2006) and the Sanitary Standard for Drinking Water (GB 5749—2006) for the rural school network in Guanzhong area. The peripheral water collection and testing carried out single factor and multifactor statistical analysis on the relationship between water quality influencing factors and water quality pass rate. Results: The total qualified rate of drinking water quality in rural schools in Guanzhong area was 59.1%. Univariate analysis showed that water quality rate was affected by four factors including water source type, engineering type, sanitation permit and disinfection equipment use, and the difference was statistically significant(P<0.05). Unconditional two-class logistic regression analysis showed that disinfection (OR=3.14), engineering type (OR=2.05), and sanitation permit (OR=1.99)(P<0.05) affected the water quality pass rate. Conclusion It is recommended to further strengthen the investment in the renovation of water supply for rural schools in Guanzhong area, and specifically strengthen water supply treatment and standard disinfection.

Objective To understand the status and dynamic changes in the treatment of rural garbage and sewage in Shaanxi Province and provide the basis for relevant departments to formulate policies and measures. Methods Every year from 2016 to 2018, 600 administrative villages in 30 agricultural counties were randomly selected as monitoring points, and 3 000 households were selected as monitoring households. Monitoring data was obtained through data reading, interviews, and on-site observations. Results The three-year rural population coverage rate of the garbage treatment plant was 28.31%, 36.10%, 39.36%, respectively, and the sewage treatment plant coverage rate was 12.27%, 20.39%, 15.02%, respectively. The annual differences were statistically significant（χ²=23.24、22.42，P=0.00）. The proportion of monitoring points for the three-year unified collection of domestic garbage was 30.50%, 43.67%, 51.00%, respectively, and the percentage of monitoring points for incineration garbage was 16.67%, 15.00%, 8.33%, respectively, and the annual differences were statistically significant（χ²=53.25、20.19，P=0.00）. The proportion of domestic sewage discharge monitoring points through pipelines was 12.67%, 11.17%, 31.17%, respectively, and the proportion of monitoring points discharged into treatment plants was 4.33%, 6.00%, 15.17%, respectively, and the annual differences were both statistically significant（χ²=99.45、52.50，P=0.00）. Conclusion In recent years, the rural garbage and sewage treatment situation in Shaanxi Province had improved, but there was still much room for improvement. It is recommended to increase environmental protection publicity and government investment, strengthen daily supervision, pay equal attention to construction and management, control the random stacking and discharging of garbage and sewage, and enhance the disposal rate of garbage and sewage.

Objective:To explore the current research status and development trend of burn nursing in China so as to provide a reference for improving nursing quality for burn patients.Methods:Retrieve the burn nursing related literatures included in China National Knowledge Infrastructure (CNKI) and Wanfang Database. The search period was from January 1, 2009 to September 30, 2019, and the retrieval time was October 5, 2019. CiteSpace information visualization software and bibliometrics methods were used to analyze knowledge maps of keywords, institutions, and authors in burn nursing literatures.Results:A total of 3 611 literatures were screened. From 2009 to 2018, domestic research literatures of burn nursing presented a stable trend on the whole. The year with the largest number of articles was 2012 with 343 articles, the least was 2015 with 270 articles, and the number of articles in most years was 270 to 330. The author with the highest volume of articles published a total of 16 articles and 22 institutions published more than or equal to 10 articles. From January 2009 to September 2019, high-frequency keywords in the field of burn nursing appeared in the following order: large-area burn, severe burn, psychological care, pediatric burn, nursing intervention, quality of life, rehabilitation nursing, inhalation injury, health education, first aid, complications, head and face burn.Conclusions:The published year, literature quantities, authors and research institutions present a scattered and unbalanced distribution, and the quality of life of burn patients has gradually developed into a research hotspot. However, there is little scientific research cooperation between the authors and institutions. It is suggested that scholars and institutions strengthen collaboration between regions and teams so as to promote the development of burn nursing research and improve the quality of burn nursing.

Objective: To understand the disinfection status and microbial pollution of water supply project in rural schools in Shaanxi Province in 2018, and to provide basis for improving drinking water quality in rural schools. Methods: Data of water quality of water supply project in rural schools of Shaanxi Province in 2018 was collected, and the disinfectant surplus and microbial index compliance rate were analyzed according to "Sanitary Standard for Drinking Water" (GB 5749-2006). Results: The overall compliance rate of microbial indicators of water supply projects in rural schools in Shaanxi Province was 68.09%, and that of groundwater microbial indicators(71.97%) was higher than that of surface water(61.42%)(χ2=15.68, P<0.01); The overall compliance rate of microbial indicators in flood season(71.85%) was higher than that in dry season(64.34%)(χ2=7.44, P<0.01); The rate of reaching the standard of disinfectant residue was 77.27%. The rate of reaching the standard of microbial index of water samples with disinfection measures was higher than that of water samples without disinfection measures (χ2=31.88, P<0.01), The rate of reaching the standard of microbial index of water samples with disinfectant residue(88.89%) was higher than that of water samples with disinfectant residue(44.44%)(χ2=12.28, P<0. 01). Conclusion The main cause of microbial contamination of drinking water in rural schools in Shaanxi Province is inadequate equipment of disinfection equipment in water supply projects or not being used as required. It is suggested that schools, education and health departments should take measures to strengthen supervision and management of water plants to ensure the normal use of disinfection equipment.

Objective: To understand the environmental sanitation situation of rural schools in different geographical areas of Shaanxi, and to provide scientific basis for improving hygiene and sanitation in Chinese rural schools. Methods: Each year during 2016 to 2018, 150 townships in 30 counties of rural areas were randomly selected in various districts and cities throughout the province. In each township one junior high school and one elementary school were randomly selected, and the data was obtained through resource access, interviews, and on-site observations. The data was statistically analyzed and evaluated according to the northern, central and southern regions. Results: The differences of drinking ways among students in the schools were of statistical significance(χ2=25.89,P<0.01). The major drinking water method of students in the monitoring schools of the three regions all was providing boiled water, accounting for 56.16%, 65.88%, 50.39%, all of which have direct drinking unboiled water phenomenon; The water supply method of the self-provided centralized water supply school is mainly precipitation filtration in the central and southern regions, accounting for 38.46%, 53.21%, and untreated in the northern region(60.61%); The differences of the proportions of having sanitary toilets, detached toilets in schools, having toilets in teaching buildings, and having toilets in dormitory buildings in three regions were of statistical significance(χ2=32.04, 12.73, 20.78, 33.11, P<0.01) The proportion of schools with squat toilets in men’s toilets was greater than that of women’s(χ2=86.53, 44.77, 21.88, P<0.01). The differences of the proportion of schools with faucets available in toilets and within 5 meters around toilets, with sinks in or around the toilets, with sinks equipped with soap in or around the toilets were of statistical significance(χ2=90.02, 10.40, 41.96, P<0.01). Conclusion During 2016 to 2018, the environment sanitation of the three major rural primary and middle schools in Shaanxi Province needs to improve corresponding supporting facilities, and increase publicity to improve teachers and students’ awareness of health and safety.