Portal hypertension is a major complication of cirrhosis. The current gold standard for diagnosis is the hepatic venous pressure gradient, but it possesses limitations such as invasiveness. In recent years, non-invasive tests have made significant progress in terms of evaluating and prognostication of portal hypertension. This article reviews the diagnostic value and related research advancements of different non-invasive tests in assessing portal hypertension in patients with cirrhosis.

Portal hypertension is a major complication of cirrhosis. The current gold standard for diagnosis is the hepatic venous pressure gradient, but it possesses limitations such as invasiveness. In recent years, non-invasive tests have made significant progress in terms of evaluating and prognostication of portal hypertension. This article reviews the diagnostic value and related research advancements of different non-invasive tests in assessing portal hypertension in patients with cirrhosis.

Recently, organ support therapy for liver failure has made rapid progress in the direction of clearing bile acids, blood ammonia, and inflammatory factors. However, there is still a lack of high-level evidence-based medicine, necessitating extensive research on the pathogenesis of major subtypes of liver failure so as to explore collaborative key points of clinical research design decisions for appropriate organ support therapy.

Recently, organ support therapy for liver failure has made rapid progress in the direction of clearing bile acids, blood ammonia, and inflammatory factors. However, there is still a lack of high-level evidence-based medicine, necessitating extensive research on the pathogenesis of major subtypes of liver failure so as to explore collaborative key points of clinical research design decisions for appropriate organ support therapy.