Recurrent lumbar disc herniation occurs in 5%–15% of patients following discectomy, with 20%–30% of these patients also presenting lumbar spinal stenosis. Traditional treatments, such as rediscectomy or spinal fusion, are effective but invasive, often associated with higher complication rates and prolonged recovery periods. Recent advancements in endoscopic techniques—specifically unilateral biportal endoscopic (UBE) laminotomy with bilateral decompression (ULBD) and percutaneous endoscopic lumbar discectomy (PELD)—offer less invasive alternatives. In this technical report, 2 patients with multilevel lumbar pathologies underwent a hybrid surgical approach combining UBE-ULBD and PELD, achieving successful decompression and pain-free discharge. These endoscopic methods effectively remove disc fragments and calcifications with minimal tissue disruption, while continuous irrigation during surgery maintains clear visualization, reduces intraoperative bleeding, and lowers infection risk. This staged approach addresses adjacent-level pathologies in a single surgical session, significantly reducing recovery time and complications compared to open surgical methods. As endoscopic spine surgery continues to evolve, precise surgical planning and specialized training are essential for optimal patient outcomes, underscoring the potential of these techniques to expand minimally invasive treatment options for complex lumbar spine conditions.