1.iPARTY study: Increasing pre-exposure prophylaxis access and reach via telehealth for young men who have sex with men in Singapore 2022-2023.
Pei Hua LEE ; Justin Y LIM ; P Arun KUMAR ; Zhi Hui TAN ; Rayen Bing Hui TAN ; Chiaw Yee CHOY ; Rayner Kay Jin TAN ; Martin Tw CHIO ; Chen Seong WONG
Annals of the Academy of Medicine, Singapore 2025;54(3):160-169
INTRODUCTION:
Although pre-exposure prophylaxis (PrEP) has been available in Singapore since 2016, its uptake among gay, bisexual and other men-who-have-sex-with-men (GBMSM) is low. The iPARTY study was established to evaluate the acceptability and feasibility of PrEP and a PrEP teleconsultation service for young GBMSM aged 18 to 29 years.
METHOD:
A total of 53 young GBMSM were enrolled in the iPARTY study. They had a total of 5 in-person consultations and teleconsultations, at 12-week intervals. Laboratory tests and quarterly baseline surveys were performed to assess PrEP adherence, sexual behaviour, and incidence of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs).
RESULTS:
Thirty-five participants completed the entire 12-month follow-up. Most participants had positive experiences with PrEP teleconsultations. There was a statistically significant fall in participants' aggregate Patient Health Questionnaire-9 scores throughout the study. Self-reported PrEP adherence decreased over the course of the study, denoting improved mental health. Although self-reported condom use for anal intercourse and participants' risk perception of HIV decreased after PrEP adoption, there was no statisti-cally significant increase in STI incidence.
CONCLUSION
This pilot project has shown that PrEP services provide an opportunity for YMSM to access sexual health testing, treatment and counselling, and may even have tangible benefits on the mental health of this population. Teleconsultation is shown to be a suitable platform for the delivery of such services. Collaborative initiatives are crucial to further enhance the affordability and accessibility of PrEP in Singapore, and to improve patient adherence.
Adolescent
;
Adult
;
Humans
;
Male
;
Young Adult
;
Anti-HIV Agents/administration & dosage*
;
Feasibility Studies
;
Health Risk Behaviors
;
HIV Infections/psychology*
;
Incidence
;
Medication Adherence
;
Mental Health/statistics & numerical data*
;
Pilot Projects
;
Pre-Exposure Prophylaxis/statistics & numerical data*
;
Sexual and Gender Minorities/statistics & numerical data*
;
Sexually Transmitted Diseases/prevention & control*
;
Singapore/epidemiology*
;
Telemedicine/statistics & numerical data*
;
Homosexuality, Male/statistics & numerical data*
2.Factors associated with medication compliance among hypertensive patients in Barangay Sambag II, Cebu City.
Katrina Isabel A. Abesta ; Stacy Gayle N. Auza ; Avinash Suram ; Francis Keith A. Oludin ; Jonathan P. Abrenilla ; Joy Ochoyafie Oche ; Maria Dawn F. Amante ; Millicent C. Abayan ; Pamela Kaye B. Pandili ; Rex Moller Q. Palmes ; Yanilen A. Noynay ; Anacleto Clent L. Banaay jr. ; Marvin C. Masalunga
Acta Medica Philippina 2025;59(Early Access 2025):1-7
BACKGROUND
Medication compliance contributes to preventing significant morbidities, such as stroke, among hypertensive patients.
OBJECTIVEThis study aimed to examine the factors affecting hypertensive patients' medication compliance in Sambag II, Cebu City.
METHODSThis study is an observational cross-sectional study. The study was conducted in Barangay Sambag II of Cebu City and involved 170 random, voluntary, self-reporting hypertensive patients. The Tao Yamane formula was used to determine the sample size. An interviewer-guided survey questionnaire was utilized to collect the data for the pilot study. The data were analyzed using Cronbach’s Alpha Test for internal consistency and reliability.
RESULTSThree factors were shown to influence compliance with antihypertensive medications. These are the source of medication, access to medication, and symptoms experienced before intake of anti-hypertensive medications. A factor that significantly affects compliance is the source of medication, wherein hypertensive patients prefer medications from retail pharmacies compared to the free medications supplied by the local health center.
CONCLUSIONResidents of Sambag II, Cebu City preferred medications from retail pharmacies over the free medications provided by the local health center. Local health units may use this information to implement information drugs regarding the efficacy of medications provided by government agencies. Further studies are recommended to use subgroup analysis on factors influencing compliance and non-compliance to anti-hypertensive medicines.
Human ; Medication Compliance ; Medication Adherence ; Hypertension ; Stroke
3.Factors associated with medication compliance among hypertensive patients in Barangay Sambag II, Cebu City.
Katrina Isabel A. ABESTA ; Stacy Gayle N. AUZA ; Avinash SURAM ; Francis Keith A. OLUDIN ; Jonathan P. ABRENILLA ; Joy Ochoyafie OCHE ; Maria Dawn F. AMANTE ; Millicent C. ABAYAN ; Pamela Kaye B. PANDILI ; Rex Moller Q. PALMES ; Yanilen A. NOYNAY ; Anacleto Clent L. BANAAY JR. ; Marvin C. MASALUNGA
Acta Medica Philippina 2025;59(18):9-15
BACKGROUND
Medication compliance contributes to preventing significant morbidities, such as stroke, among hypertensive patients.
OBJECTIVEThis study aimed to examine the factors affecting hypertensive patients' medication compliance in Sambag II, Cebu City.
METHODSThis study is an observational cross-sectional study. The study was conducted in Barangay Sambag II of Cebu City and involved 170 random, voluntary, self-reporting hypertensive patients. The Tao Yamane formula was used to determine the sample size. An interviewer-guided survey questionnaire was utilized to collect the data for the pilot study. The data were analyzed using Cronbach’s Alpha Test for internal consistency and reliability.
RESULTSThree factors were shown to influence compliance with antihypertensive medications. These are the source of medication, access to medication, and symptoms experienced before intake of anti-hypertensive medications. A factor that significantly affects compliance is the source of medication, wherein hypertensive patients prefer medications from retail pharmacies compared to the free medications supplied by the local health center.
CONCLUSIONResidents of Sambag II, Cebu City preferred medications from retail pharmacies over the free medications provided by the local health center. Local health units may use this information to implement information drugs regarding the efficacy of medications provided by government agencies. Further studies are recommended to use subgroup analysis on factors influencing compliance and non-compliance to anti-hypertensive medicines.
Human ; Medication Compliance ; Medication Adherence ; Hypertension ; Stroke
4.Is satisfaction with the medication provisions of the Senior Citizens Act and frequency of senior identification card use associated with medication compliance among hypertensive patients in the Philippines?.
Nativity R. LABBAO ; Mary Kriznah S. HIDALGO ; Ram Joseph D. DOROLIAT ; Daisy-mae ALEGADO-BAGAOISAN ; Kevin Jace A. MIRANDA ; Rogie Royce Z. CARANDANG
Acta Medica Philippina 2025;59(17):16-23
BACKGROUND
Long-term treatment and medication compliance are critical for managing conditions like hypertension, yet only 20% of cases are well-controlled, mainly due to socioeconomic factors. The Expanded Senior Citizens Act of 2010 offers a 20% discount on medications to improve compliance, but many seniors need to be made aware of these benefits. Evaluating satisfaction with the Act, specifically regarding its medication-related provisions, is essential for enhancing compliance and health outcomes among senior citizens.
OBJECTIVEThis study examined the association between satisfaction with the medication provisions of the Senior Citizens Act, the frequency of senior identification card usage, and medication compliance among hypertensive patients.
METHODSWe conducted a community-based cross-sectional study with 458 hypertensive senior citizens in Dasmariñas City, Cavite, Philippines. Senior citizens were randomly selected and completed a survey using a validated, self-developed questionnaire and the Hill-Bone High Blood Pressure (HB-HBP) compliance scale. We performed linear regression analysis to examine the association between their satisfaction and the use of senior citizens’ benefits on their medication compliance.
RESULTSSenior citizens were 60-88 years old (mean 69; standard deviation [SD] 5.9). Thirty-eight percent were satisfied with the Senior Citizens Act and 49% regularly used their senior citizen card. Senior citizens scored an average of 46.82 (SD 4.96) on the HB-HBP compliance scale (possible range = 14-56), indicating high compliance. Those dissatisfied with the Senior Citizens Act were less compliant with their antihypertensive medications [B (unstandardized beta) = -1.65, 95% CI (Confidence Interval) = -2.70, -0.61]. Similarly, those who rarely or never used their senior identification cards (B = -1.54, 95% CI = -2.61, -0.48) and those who used them occasionally (B = -1.43, 95% CI = -2.57, -0.29) showed lower medication compliance compared to those who used them regularly.
CONCLUSIONSenior citizens who are satisfied with the medication provisions of the Act and regularly use their senior identification cards exhibit higher compliance with their antihypertensive medications than those with lower satisfaction and infrequent card usage. Interventions should prioritize educational sessions to inform senior citizens about the benefits of the Senior Citizens Act, including how to use their identification cards to access medication discounts effectively.
Human ; Hypertension ; Medication Adherence ; Philippines ; Satisfaction ; Personal Satisfaction
5.Latent profile types and influencing factors of medication adherence mechanisms among rural older adults with multiple chronic conditions.
Zhige YAN ; Jun ZHOU ; Xing CHEN ; Yao WANG
Journal of Central South University(Medical Sciences) 2025;50(8):1443-1454
OBJECTIVES:
Older adults in rural areas with multiple chronic conditions (MCC) generally exhibit poorer medication adherence than the general elderly population. Considering individual heterogeneity helps to design precise subgroup-based interventions. This study aims to identify latent profile types of medication adherence mechanisms among rural older adults with MCC based on the capability-opportunity-motivation-behavior (COM-B) model, and to explore factors influencing medication adherence.
METHODS:
A multistage sampling method was used to recruit 349 rural older adults with MCC from 10 administrative villages in Jianghua County, Yongzhou City, Hunan Province, between July and September, 2024. Participants were surveyed using a general information questionnaire, the Health Literacy Scale for Chronic Patients, the Beliefs about Medicines Questionnaire-Specific, the Multidimensional Scale of Perceived Social Support, and the Morisky Medication Adherence Scale. Latent profile analysis based on the COM-B model was conducted to identify subgroups of medication adherence mechanisms. Univariate and Logistic regression analyses were used to identify influencing factors associated with different latent profiles and adherence levels.
RESULTS:
Among the participants, 33.5% demonstrated good medication adherence. The 5 most prevalent chronic diseases were hypertension (86.5%), diabetes (36.7%), arthritis or rheumatism (34.4%), stroke (21.8%), and heart disease (17.5%). Overall, rural older adults with MCC exhibited relatively good medication capability, opportunity, and motivation. Their medication adherence mechanisms were classified into 3 latent profiles: "family-support restrained type" (5.2%), "family-support driven type" (52.1%), and "comprehensive advantage type" (42.7%). Significant differences were observed among the three profiles in terms of education level, marital status, living arrangement, and per capita monthly household income (all P<0.05). Multivariate Logistic regression revealed that higher education level was a protective factor for belonging to the "comprehensive advantage type" rather than the "family-support driven type" [OR=0.277, 95% CI (PL) 0.126 to 0.614, P=0.002]. Furthermore, significant differences in education level, self-rated health status, and latent profile type were found between participants with good and poor adherence (P<0.05). Binary Logistic regression indicated that with each one-level increase in self-rated health status, the risk of poor adherence increased by 293.9% [OR=3.939, 95% CI (PL) 1.610 to 9.636, P=0.003]. Compared with the "family-support restrained type", individuals classified as the "comprehensive advantage type" had a 96.8% [OR=0.032, 95% CI (PL) 0.008 to 0.123, P<0.001] lower risk of poor medication adherence.
CONCLUSIONS
The mechanisms underlying medication adherence among rural older adults with MCC show clear heterogeneity. Primary healthcare providers should focus on the "family-support restrained type" subgroup, strengthen social support networks, and implement targeted interventions to improve medication adherence.
Humans
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Aged
;
Rural Population
;
Male
;
Female
;
China
;
Medication Adherence/psychology*
;
Surveys and Questionnaires
;
Chronic Disease/drug therapy*
;
Multiple Chronic Conditions/drug therapy*
;
Social Support
;
Motivation
;
Middle Aged
;
Health Literacy
;
Aged, 80 and over
6.Analysis of factors related to voice training compliance.
Caipeng LIU ; Jinshan YANG ; Wenjun CHEN ; Xin ZOU ; Yajing WANG ; Yiqing ZHENG ; Faya LIANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2025;39(7):610-623
Objective:To explore the factors influencing adherence to voice therapy among patients with voice disorders in China. Methods:Patients with voice disorders who visited the Voice Therapy Center at Sun Yat-sen Memorial Hospital, Sun Yat-sen University, from February to May 2022 were enrolled in the study. Adherence was assessed using the URICA-Voice scale, while influencing factors were assessed through the Voice Handicap Index(VHI) scale and a general information questionnaire. Correlation analysis was conducted using univariate and multivariate logistic regression analysis. Results:A total of 247 patients were included in the study, comprising 57 males(23.08%) and 190 females(76.92%). The results revealed that: ①Female patients demonstrated higher likelihood of being in the contemplation stage(OR=0.22) compared to males. ②Patients with a monthly family income per capita>6 000 yuan were more likely to be in the contemplation stage than those with<3 000 yuan with an OR = 13.94. ③High vocal-demand occupations increased contemplation stage probability(OR=7.70) compared to moderate-demand occupations. ④Residence within 30-minute commute predicted action/maintenance stages(OR=7.14) versus≥60-minute commute. ⑤Patients whose occupations had high voice demands were more likely to be in the action and maintenance stages than those with average voice demands, with an OR of 16.20. Conclusion:Gender, monthly family income per capita, occupational voice demands, and distance to the hospital significantly impact the URICA-Voice compliance stages of patients. Patients who are female, have higher family income, have occupations with high voice demands, and live closer to the hospital exhibit higher compliance with voice training.
Humans
;
Male
;
Female
;
Voice Disorders/therapy*
;
Patient Compliance
;
Voice Training
;
Surveys and Questionnaires
;
China
;
Middle Aged
;
Adult
;
Voice Quality
;
Logistic Models
;
Aged
7.Clinical exploration and practice of a 16-step new model of comfortable supragingival scaling.
Yue CHEN ; Jinyang LI ; Yazheng WANG ; Jing LI ; Jin LIU ; Yumeng ZHOU ; Ang LI
West China Journal of Stomatology 2025;43(5):628-635
Comfortable supragingival scaling uses ultrasonic cleaning with sedation and minimally invasive techniques to minimize the negative emotions of patients and improve patient compliance. At present, there is still much room for optimization of the environment, equipment, and operation steps for the development of comfortable supragingival scaling. On this basis, the Department of Periodontology, College of Stomatology, Xi'an Jiaotong University proposed a 16-step new model of comfortable supragingival scaling. The new model incorporates adjustments to the previous model concerning the environment, equipment, operational procedures, process links and services, comprising 16 steps for optimization and innovation. Clinical practice has confirmed that the 16-step new model of comfortable supra-gingival scaling can significantly improve patient satisfaction and adherence to medical treatment, and it has good promotional value.
Humans
;
Dental Scaling/instrumentation*
;
Patient Satisfaction
;
Patient Compliance
;
Gingiva
8.Is satisfaction with the medication provisions of the Senior Citizens Act and frequency of senior identification card use associated with medication compliance among hypertensive patients in the Philippines?
Nativity R. Labbao ; Mary Kriznah S. Hidalgo ; Ram Joseph D. Doroliat ; Daisy-Mae Alegado-Bagaoisan ; Kevin Jace A. Miranda ; Royce Z. Carandang
Acta Medica Philippina 2024;58(Early Access 2024):1-8
Background:
Long-term treatment and medication compliance are critical for managing conditions like hypertension, yet only 20% of cases are well-controlled, mainly due to socioeconomic factors. The Expanded Senior Citizens Act of 2010 offers a 20% discount on medications to improve compliance, but many seniors need to be made aware of these benefits. Evaluating satisfaction with the Act, specifically regarding its medication-related provisions, is essential for enhancing compliance and health outcomes among senior citizens.
Objective:
This study examined the association between satisfaction with the medication provisions of the Senior Citizens Act, the frequency of senior identification card usage, and medication compliance among hypertensive patients.
Methods:
We conducted a community-based cross-sectional study with 458 hypertensive senior citizens in Dasmariñas City, Cavite, Philippines. Senior citizens were randomly selected and completed a survey using a validated, self-developed questionnaire and the Hill-Bone High Blood Pressure (HB-HBP) compliance scale. We performed linear regression analysis to examine the association between their satisfaction and the use of senior citizens’ benefits on their medication compliance.
Results:
Senior citizens were 60-88 years old (mean 69; standard deviation [SD] 5.9). Thirty-eight percent were satisfied with the Senior Citizens Act and 49% regularly used their senior citizen card. Senior citizens scored an average of 46.82 (SD 4.96) on the HB-HBP compliance scale (possible range = 14-56), indicating high compliance. Those dissatisfied with the Senior Citizens Act were less compliant with their antihypertensive medications [B (unstandardized beta) = -1.65, 95% CI (Confidence Interval) = -2.70, -0.61]. Similarly, those who rarely or never used their senior identification cards (B = -1.54, 95% CI = -2.61, -0.48) and those who used them occasionally (B = -1.43, 95% CI = -2.57, -0.29) showed lower medication compliance compared to those who used them regularly.
Conclusion
Senior citizens who are satisfied with the medication provisions of the Act and regularly use their senior identification cards exhibit higher compliance with their antihypertensive medications than those with lower satisfaction and infrequent card usage. Interventions should prioritize educational sessions to inform senior citizens about the benefits of the Senior Citizens Act, including how to use their identification cards to access medication discounts effectively.
Human
;
hypertension
;
medication adherence
;
Philippines
;
satisfaction
;
personal satisfaction
9.Socioeconomic disparities in hypertension medication adherence in Quezon City: A cross-sectional study
Jamee G. Lanag ; Carolyn A. Lavadia ; Daniel Royce Lee ; Richelle Anne L. Matias ; Johanna Arndriella M. Mendoza ; Marianne Claire M. Morales ; Ina Mulingbayan ; Jose Ronilo Juangco ; Norbert Lingling D. Uy
Health Sciences Journal 2024;13(2):63-68
INTRODUCTION:
Hypertension is a major risk factor for cardiovascular diseases, with adherence to treatment often influenced by socioeconomic status. This study assessed adherence to hypertension medication among patients in Quezon City across economic classes from August to October 2023.
METHODS:
An analytical cross-sectional design was employed, surveying 116 hypertensive Filipinos aged 18-64 years using the Brief Medication Questionnaire-1 (BMQ-1) and socioeconomic classifications based on multiples of the poverty line.
RESULTS:
Findings revealed that 50.9% of respondents were adherent or probably adherent to treatment, while 49.1% exhibited low or probable low adherence. Those who are low adherent and probable low adherent are 1.399 times more likely to belong to the “Low Income and Below.”, though this association was not statistically significant.
CONCLUSION
Adherence to hypertension treatment among the respondents was suboptimal, particularly among the lower-income groups. While the association between socioeconomic status and adherence was not statistically significant, the findings underscore the need for interventions targeting financial barriers and improving healthcare accessibility. Addressing these challenges can enhance adherence levels and reduce the burden of hypertension and cardiovascular risks across socioeconomic strata.
Cardiovascular diseases
;
hypertension
;
prescription drugs
;
medication adherence
;
developing countries
10.Effect of SMS reminders to medication adherence among hypertensives in an outpatient clinic: A 12-week two-arm, parallel group randomized clinical trial.
Penny Joy H. Barbadillo ; Yahya-Mar M. Alip ; Hans Mathew Lua
The Filipino Family Physician 2024;62(1):67-78
BACKGROUND
There has been a growing prevalence of hypertension and its associated diseases. Medication adherence is one of the primary factors of uncontrolled blood pressure in patients and non-adherence to medication can result in morbidity and mortality for the patient and increased financial strain on the healthcare system. With the wide availability of mobile phones, using short messaging system (SMS) reminders as an intervention has shown promising results in improving medication adherence. The present study aims to see if SMS reminders can help improve medication adherence among hypertensive patients seen in the out-patient department.
OBJECTIVETo determine the effect of short messaging system reminders on the medication adherence among hypertensive patients seen in the outpatient department of Cebu South Medical Center (CSMC) in a 12-week trial period.
METHODSThis was a two-arm parallel group, double blind, randomized clinical trial using short text messaging reminder to hypertensive patients conducted last October 4, 2023 to December 27, 2023 at CSMC Outpatient Clinic under Family Medicine Service. A two-part questionnaire composed of baseline clinical variables and the Hill-bone Medication Adherence Scale (HBMAS) (Kim, et al 2000) was utilized pre- and post-intervention. STATA Software was used to analyze the date with intention to treat analysis. Descriptive statistics was computed for dichotomous variables while continuous variables were expressed as means and measured before and after intervention. The mean HB-MAS scores pre intervention and post-intervention per group were compared using the Wilcoxon signed rank test, while scores between intervention and control groups pre- and post-intervention were analyzed using the Wilcoxon rank-sum test with 95% confidence intervals (CIs), with two-sided p values reported and statistical significance set up at p < 0.05.
RESULTSA total of 102 patients were enrolled in the study (51 in intervention group and 51 in control group) with no dropouts. There was no significant difference between the baseline and post intervention medication adherence scores in both the intervention and control groups, however, there was a significant difference of the scores between the intervention and control groups post intervention (p = 0.001). There was also noted improvement of the blood pressure among participants in the intervention group, with lower blood pressures post-intervention on average (120/80 mmHg) compared to baseline (130/90 mmHg), while participants in the control group still exhibited high blood pressure (130/90 mmHg) post-intervention.
CONCLUSIONGiven the widespread availability of mobile devices and the increased awareness generated by social media, it may be easier to put interventions in place that improve drug adherence. Through the use of easily accessible technology, this study helps patients remember to take their prescription by offering straightforward reminders that can help them overcome these obstacles to medication adherence.
Medication Adherence


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