5.Anesthesiological management in endovascular mechanical thrombectomy: a propensity score-matched retrospective analysis in Italy
Antonio ROMANELLI ; Aniello IOVINO ; Antonella LANGONE ; Rosa NAPOLETANO ; Giulia FRAUENFELDER ; Flora MINICHINO ; Liliana D’AMBROSIO ; Miriam CATERINO ; Raffaele TORTORA ; Renato GAMMALDI ; Paolo BARONE ; Renato SAPONIERO ; Daniele Giuseppe ROMANO
Acute and Critical Care 2025;40(2):252-263
Background:
Endovascular mechanical thrombectomy (EMT) can be performed with general anesthesia (GA) or using non-GA techniques. Several meta-analyses on the topic have reported discordant main outcomes. The aim of this retrospective single-center study was to analyze the relationship between clinical outcomes and anesthesiological management (GA vs. non-GA) in patients who underwent EMT for acute anterior ischemic stroke (AIS).
Methods:
We performed a propensity score-matched (PSM) analysis of patients who underwent EMT for acute AIS from January 2018 to December 2021. For PSM, we chose covariates influencing clinical decisions about anesthesiological management. Comparisons between groups were performed with the chi-square test for categorical variables and Student t-test or the Mann-Whitney U-test for continuous variables as appropriate. The relationships between anesthesiological management and clinical outcomes were analyzed using logistic regression, and results are reported as odds ratios with 95% confidence intervals. A two-sided P-value <0.05 was considered statistically significant.
Results:
From 194 observations (78 in the GA group, 116 in the non-GA group), after PSM, we obtained 70 data pairs. Both anesthesiological approaches resulted in similar rates of in-hospital mortality, 90-day functional independence, full recanalization, procedural complications, and intracerebral hemorrhage (ICH). Performing EMT with GA was unrelated to the in-hospital and 90-day death rates, 90-day functional independence, full recanalization rate, procedural complications, and ICH (P>0.05).
Conclusions
Anesthesiological management did not influence clinical outcomes of EMT for acute AIS. Physiological stability during EMT may impact outcomes more significantly than anesthesiological management. Further studies on this topic are needed.
8.Influence of implant mucosal thickness on early bone loss: a systematic review with meta-analysis
Riccardo Di GIANFILIPPO ; Nicola Alberto VALENTE ; Paolo TOTI ; Hom-Lay WANG ; Antonio BARONE
Journal of Periodontal & Implant Science 2020;50(4):209-225
Purpose:
Marginal bone loss (MBL) is an important clinical issue in implant therapy. One feature that has been cited as a contributing factor to this bone loss is peri-implant mucosal thickness. Therefore, in this report, we conducted a systematic review of the literature comparing bone remodeling around implants placed in areas with thick (≥2-mm) vs. thin (<2-mm) mucosa.
Methods:
A PICO question was defined. Manual and electronic searches were performed of the MEDLINE/PubMed and Cochrane Oral Health Group databases. The inclusion criteria were prospective studies that documented soft tissue thickness with direct intraoperative measurements and that included at least 1 year of follow-up. When possible, a meta-analysis was performed for both the overall and subgroup analyses.
Results:
Thirteen papers fulfilled the inclusion criteria. A meta-analysis of 7 randomized clinical trials was conducted. Significantly less bone loss was found around implants with thick mucosa than around those with thin mucosa (difference, −0.53 mm; P<0.0001).Subgroups were analyzed regarding the apico-coronal positioning, the use of platformmatched vs. platform-switched (PS) connections, and the use of cement-retained vs.screw-retained prostheses. In these analyses, thick mucosa was found to be associated with significantly less MBL than thin mucosa (P<0.0001). Among non-matching (PS) connections and screw-retained prostheses, bone levels were not affected by mucosal thickness.
Conclusions
Soft tissue thickness was found to be correlated with MBL except in cases of PS connections used on implants with thin tissues and screw-retained prostheses.Mucosal thickness did not affect implant survival or the occurrence of biological or aesthetic complications.Trial Registration: International Prospective Register of Systematic Reviews (PROSPERO):CRD42018084598
9.Ethics and Plastic Surgery/What is Plastic Surgery?.
Mauro BARONE ; Annalisa COGLIANDRO ; Paolo PERSICHETTI
Archives of Plastic Surgery 2017;44(1):90-92
No abstract available.
Ethics*
;
Plastics*
;
Surgery, Plastic*
10.Cognitive Investigation Study of Patients Admitted for Cosmetic Surgery: Information, Expectations, and Consent for Treatment.
Mauro BARONE ; Annalisa COGLIANDRO ; Giuseppe LA MONACA ; Vittoradolfo TAMBONE ; Paolo PERSICHETTI
Archives of Plastic Surgery 2015;42(1):46-51
BACKGROUND: In all branches of medicine, it is the surgeon's responsibility to provide the patient with accurate information before surgery. This is especially important in cosmetic surgery because the surgeon must focus on the aesthetic results desired by the patient. METHODS: An experimental protocol was developed based on an original questionnaire given to 72 patients. The nature of the responses, the patients' motivation and expectations, the degree of patient awareness regarding the planned operation, and the patients' perceptions of the purpose of the required consent for cosmetic surgery were all analyzed using Fisher's exact test. RESULTS: Candidates for abdominal wall surgery had significantly more preoperative psychological problems than their counterparts did (P=0.035). A significantly different percentage of patients under 40 years of age compared to those over 40 years of age searched for additional sources of information prior to the operation (P=0.046). Only 30% of patients with a lower educational background stated that the preoperative information had been adequate, whereas 92% of subjects with secondary schooling or a postsecondary degree felt that the information was sufficient (P=0.001). A statistically significant difference was also present between patients according to their educational background regarding expected improvements in their quality of life postoperatively (P=0.008). CONCLUSIONS: This study suggests that patients require more attention in presurgical consultations and that clear communication should be prioritized to ensure that the surgeon understands the patient's expectations.
Abdominal Wall
;
Humans
;
Informed Consent
;
Motivation
;
Quality of Life
;
Referral and Consultation
;
Surgery, Plastic*
;
Surveys and Questionnaires

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