Background: Inflammatory bowel disease (IBD) is a chronic immune-related condition caused by interactions between genetics, immune dysfunction, gut microbiota changes, and environmental factors, often presenting as persistent or recurring diarrhea. Clinically, it commonly presents with chronic diarrhea and other gastrointestinal symptoms. The global prevalence of IBD is increasing, currently affecting approximately 0.5% of the population, with projections suggesting a rise to nearly 1% by 2030. Fecal calprotectin is a neutrophil-derived S100 calcium-binding protein that is elevated in intestinal mucosal inflammation and serves as a reliable noninvasive biomarker of inflammatory activity. Due to its high stability and close association with intestinal inflammatory activity, fecal calprotectin has been established as a dependable, non-invasive marker for identifying intestinal inflammation. In clinical practice, it is extensively used to distinguish IBD from functional gastrointestinal disorders, especially irritable bowel syndrome, among patients presenting with chronic diarrhea. However, its diagnostic utility in Mongolia remains underexplored, and this study aims to determine its sensitivity and specificity in inflammatory bowel disease and compare its diagnostic performance with other inflammatory markers. Aim: To determine the sensitivity and specificity of fecal calprotectin in inflammatory bowel disease and to compare it with other inflammatory markers. Materials and Methods: A total of 109 participants aged 18-87 years with chronic diarrhea, who attended the gastroenterology outpatient clinics of the Mongolia–Japan Hospital and Intermed Hospital between December 2024 and December 2025 and provided informed consent, were enrolled in this study. Data were collected using structured questionnaires, and laboratory investigations included complete blood count, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and measurement of fecal calprotectin levels from stool samples. Based on fecal calprotectin results, selected participants underwent colonoscopic examination as clinically indicated. Results: Among the 109 participants included in the study, 17.4% were diagnosed with inflammatory bowel disease (IBD), with a mean age of 47.41±15.52 years. Fecal calprotectin levels were significantly higher in the IBD group compared to the control group (p<0.001). Fecal calprotectin demonstrated a weak positive correlation with C-reactive protein (CRP) and leukocyte count (p=0.042, p=0.06), while no significant correlation was observed with erythrocyte sedimentation rate (ESR). At a cutoff value of 250 µg/g, fecal calprotectin showed a sensitivity of 94.4%, specificity of 69.2%, positive predictive value (PPV) of 37.8%, and negative predictive value (NPV) of 98.4%. Receiver operating characteristic (ROC) curve analysis identified an optimal cutoff value of approximately 400 µg/g (AUC=0.919, Youden index=0.724), at which the sensitivity remained 94.4% and specificity increased to 78.0%. In contrast, CRP and ESR demonstrated comparatively lower diagnostic performance, with AUC values of 0.640 and 0.644, respectively. Conclusion This study demonstrates that fecal calprotectin has superior diagnostic performance compared to conventional inflammatory markers in differentiating inflammatory bowel disease (IBD). An optimal cutoff value of approximately 400 µg/g yielded the highest sensitivity and specificity. Therefore, fecal calprotectin may serve as a valuable tool in clinical practice for both screening and diagnostic confirmation.

Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary disease of the myocardium characterized by fibro-adipocytic replacement of myocytes, mostly in the right ventricle. The prevalence of ARVC in the general adult population is estimated to be approximately 1 in 2000 to 1 in 5000. ARVC is an important cause of sudden cardiac death (SCD) in young adults, accounting for approximately 11 percent of cases overall. ARVC is caused by mutations in a variety of genes, most of which encode desmosomal proteins, with greater than 30 percent of cases being familial in origin. We present a rare autopsy case of pregnant woman diagnosed with Arrhythmogenic right ventricular cardiomyopathy. Case presentation: We report a case of a 24-year-old woman at 24-25 weeks of gestation who suddenly collapsed at work and was brought to the emergency department in cardiac arrest. Despite prolonged cardiopulmonary resuscitation, she was pronounced dead. Her medical history included recurrent renal surgeries for hydronephrosis. Autopsy revealed cardiomegaly (379.4 g) with marked right ventricular dilatation, thickened and fatty epicardium, and microscopic evidence of fibrofatty replacement of right ventricular myocardium with inflammatory cell infiltration (CD3+, CD68+). Associated findings included bilateral hydronephrosis, chronic pyelonephritis, accessory liver and spleen lobes, and thoracic scoliosis. The cause of death was determined to be heart failure and arrhythmia secondary to arrhythmogenic right ventricular cardiomyopathy. Conclusion This case highlights the rare occurrence of ARVC in pregnancy complicated by multiple congenital anomalies and chronic infection. Pregnancy-related hemodynamic stress may exacerbate underlying myocardial pathology, leading to fatal arrhythmia. Early detection of cardiovascular and systemic abnormalities during prenatal care is essential to identify high-risk pregnancies and prevent sudden maternal death.

: In our country, burnt occupies a high percentage among the unexpected injuries depending on the living conditions.
Children and adults who have recovered after treatment in the burn unit may need further treatment, such as surgery to release the burn scar especially, on the movable joint of the body. It requires a lot of money. Therefore, in order to accelerate healing and solve their economic difficulties, ingredients that have been used in traditional medicine but have been proven to be effective in the past century and not used in the field of health today, should be selected from ancient medical scriptures and books and confirmed by clinical trials and introduced into the clinic. I have chosen this topic for research work. Research materials and methodology: The experimental research work was carried out based on the laboratory of the Institute of Traditional Medicine Technology and the standard methodology of modern pharmaceutical science, and according to the standard methodology of pharmacology, 2.5*2.0*2.5cm sized burn wounds were administered to white Wistar rats weighing 180-200g.
On days 0, 7, 14, 21, and 28 after the formation of the pathological model, and histological analysis of the wound healing area was performed, and the healing rate of the wound area was evaluated by mathematical calculations, and the process was confirmed by photographs. Result: By planimetry, the size of the burn wound was reduced by 2 times in the X1 treatment group compared to the control group on the 28th day. According to the results of histological analysis, inflammatory cells and hyper proliferation of fibroblast cells in the dermis layer of the rats in the untreated control group were reduced, and the bundles of collagen fibers were relatively orderly. Conclusion According to the size of the wound healing area and the histological analysis results, it was found in our research that among the tested groups, the inflammatory, granulation, and regeneration stages of the wound healing in the Version 1 group were relatively active or in a short time, and they regenerated the skin tissue.